GART
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA5
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SMC2
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TNF
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21887257
19287455
|
NFKB1
|
GSTP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15013838
|
RELA
|
GSTP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15013838
|
PPIB
|
PDIA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TXN
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19737086
|
CHUK
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
CHUK
|
IKBKB
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
RELA
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11114294
|
RELA
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
12842894
5216511
|
PNP
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ESR1
|
RAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21118977
11060289
|
NFKB1
|
SERPINA3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11027208
|
NFKB1
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11114294
|
NFKB1
|
TAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18694960
|
HSPA5
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CFTR
|
RHOQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15546864
11162552
|
ESR1
|
ABCC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15456840
23747343
|
ESR1
|
HSP90B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16511840
23038705
|
ESR1
|
ADA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11357058
18414489
|
H1-5
|
HSP90B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HYOU1
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ABCG8
|
ABCG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16870176
5218866
|
H1-5
|
PDIA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H1-1
|
ABCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H1-5
|
ABCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H1-1
|
ABCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H1-1
|
H1-5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ADSL
|
GART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CFTR
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31324722
17110338
|
RAC1
|
RAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
HYOU1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
25604459
|
RAC2
|
RAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SCN3B
|
ABCD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
PDIA6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33731348
25604459
31527615
|
ABCD2
|
ABCD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24658140
10551832
|
ADSL
|
ATIC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
IKBKB
|
NFKB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
11158290
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CFTR
|
PDIA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
31324722
29924966
|
CHUK
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
10521409
|
ABCD1
|
ABCD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22939629
10551832
|
IKBKG
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
15489227
|
SULT1A1
|
SULT1A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
AHR
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CHUK
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
RAC3
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16331275
21217774
|
IKBKB
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
GART
|
PAICS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
AHR
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15837795
19460354
12612060
27420286
17392787
10620335
9611253
|
DNAJB11
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
IKBKG
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
IKBKG
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
8209688
506093200
16126728
|
IKBKG
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15489227
|
TAP2
|
TAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
11133832
12213826
19297616
11381133
17055437
26789246
33961781
16828748
18802093
30833792
19201886
|
PDIA4
|
PPIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
34079125
24981860
22665516
30021884
|
NFKB1
|
ABCB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18234965
12527911
19763573
|
ESR1
|
CYP3A4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15358113
15499176
18299335
|
ESR1
|
ABCB10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ESR1
|
ITPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ESR1
|
TYMS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10875244
|
ESR1
|
APRT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ABCG8
|
ABCG5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12208867
16870176
27144356
|
NFKB1
|
TXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
HSPA5
|
HYOU1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
ABCG5
|
ABCG8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
IKBKB
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
CHUK
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
RRM1
|
RRM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
TAP1
|
TAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
IKBKG
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219009
16938294
|
IKBKB
|
IKBKG
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.98
|
0.98
|
mint
|
8209688
16126728
506093200
|
CHUK
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IKBKB
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IKBKG
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
IKBKG
|
CHUK
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
RELA
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
NFKB1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
TNF
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
IKBKG
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
38.0
|
1.0
|
ACSN
|
11280761
11438547
11460167
12133805
12811837
14660645
15145317
15199157
15485931
15536066
15573129
16818229
16970925
17237376
17254973
17301840
17363905
17485448
17693255
18264787
18716620
19833085
20138012
20300203
21133840
21217011
21232017
21807870
22435554
23086447
23422957
23430059
24378531
24699077
24766893
24958845
2649237
28462531
|
TNF
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
IKBKG
|
IL6
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
38.0
|
1.0
|
ACSN
|
10542212
10754326
10952726
11875494
12133805
12907458
14660645
15199157
15465827
15485931
15536066
15644117
15749903
16243976
16413922
16818229
16878026
16970925
17237376
17254973
17363905
17404308
17485448
17693255
18716620
20138012
20300203
21217011
21807870
22435554
23086447
23390297
23422957
23430059
2649237
28462531
7594497
9743347
|
NFKB1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
IKBKG
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
150.0
|
1.0
|
Omnipath
|
17145710
16938294
20932476
35339487
18266324
16260493
27929056
25979343
19666608
26496610
12133833
12192055
9751060
21423167
19706536
15836773
17561400
22099304
23986494
19959994
15327770
25400026
24266532
18450452
12657630
20434986
11583588
20200955
20300203
21903422
22990857
14743216
20167598
20098747
16126728
19656241
25852190
16906147
10195894
17000764
18329793
16186825
16547522
16611882
18037881
10968790
16497931
25286246
18462684
18207244
16603398
17965022
17977820
24240172
17568778
15084594
16129692
23506214
16319058
23123196
18949366
15218526
22605335
20368414
10837071
19820708
10980203
23131831
17363973
15214841
25304104
16493424
15184390
15691841
11864612
15802604
17693255
21455180
11865184
20211142
11971985
16970925
24469399
24618592
12486103
11057907
24369075
19365808
18583959
27426725
12612076
19422324
10094049
23109003
21803029
12459277
21640763
16285893
18266467
12709429
15620648
17072322
19815509
15749833
|
IKBKG
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17145710
17485448
16938294
11865184
11877453
16970925
22435554
17244613
17568778
17363905
16818229
15084594
15485931
24369075
20300203
21217011
12799363
23180781
14743216
16319058
21703539
19666608
20098747
12612076
16126728
15218526
23430059
9751060
20138012
18716620
20368414
10837071
25355947
15836773
23109003
20531300
17702576
17363973
15214841
12459277
17561400
21640763
16285893
28462531
12709429
10968790
15199157
26192618
12133805
16497931
11864612
17693255
17072322
11340079
|
IKBKG
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
TXN
|
RRM1
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
8.0
|
1.0
|
Reactome
|
18997010
10884394
2668278
11796141
16756507
9677297
16373698
19176520
|
TAP2
|
TAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
10973281
11717192
14508489
16181333
17204652
22076556
22790179
|
TAP2
|
TAP1
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
10973281
11717192
14508489
16181333
17204652
22076556
22790179
|
IL6
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
ESR1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23733894
15334655
16483936
12237295
20664923
|
NFKB1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17513725
12058956
24337575
12657243
17704137
12471036
17707233
7624137
11259437
12686724
16433741
26114754
20237317
7876168
16707469
12117498
14976218
10485496
15465827
8622636
15812247
21138578
18990758
10748079
15013838
15749903
16916598
17646159
10754326
16040075
10837498
18285351
11675405
11739517
15743782
20066113
20617556
17085785
8530146
8805669
10919279
14960579
1740105
10963848
16055086
9742085
17292554
10553096
11312646
15543947
17442180
16285952
10079106
11297551
10551799
10201927
12907458
8679226
9281604
22782967
8219230
11749970
9916895
11094063
11490006
7895918
1618817
16483936
18057724
20722069
16569682
9452482
17407192
17082635
|
AHR
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11470802
17588258
25690886
19703987
15627257
20181658
|
RELA
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
136.0
|
1.0
|
Omnipath
|
26596471
17707233
20817730
12686724
27075886
21765477
21537341
19530226
17390058
18077329
15064230
20617556
8805669
17351769
23335080
21573233
17292554
16285952
9916895
11749970
7895918
17496784
12628924
23857586
12657243
15857826
12471036
11259437
16433741
9831247
20237317
15465827
26023919
22661093
10748079
15013838
17350185
10754326
15470505
11827962
20139176
26408955
22901690
18772140
21108432
22742857
23195252
18362169
24012417
11312646
17442180
9281604
10079106
11297551
15081318
22718766
24908318
8219230
26004152
11094063
11490006
9916692
16483936
18057724
16569682
22138107
18467438
20547752
22723832
19846753
17407192
20221401
19854828
20534538
7876168
16707469
12117498
20544543
23178569
15812247
21138578
12610112
25888873
16916598
16040075
28039105
14749357
20066113
19285436
25161822
22388040
14960579
20195282
16199883
15543947
23971673
10551799
11290773
22798670
22021035
20722069
20221720
27338466
19385047
12058956
26997758
25690886
7624137
20686703
26114754
14976218
10485496
17607667
8622636
11007957
18285351
10837498
11739517
18719026
17268554
17085785
17142966
10963848
9742085
23042817
27534992
10553096
26516703
20696864
10201927
16850160
8679226
21098092
20097764
9129150
17082635
|
TNF
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
15192014
27329558
22240205
15833743
19351843
28187781
15841081
28107185
28373828
26999213
24386331
24957606
26179215
21572963
18258304
28317833
29441018
10722927
19596989
28423685
12881425
25118327
24036851
28089769
21904602
24141032
10938077
30201812
20691659
24166907
19789307
19393267
22768286
26310932
19411070
23789107
28790310
29708974
20507904
|
RELA
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
114.0
|
1.0
|
Omnipath
|
26596471
19124729
10373597
9523851
23595969
28270510
21537341
17982049
15226358
18243142
12200447
20371366
24664372
23874122
14532843
18942706
10975857
21278793
10469356
22547075
17490702
11459775
23335080
10569191
19707556
19687301
7499267
8290595
23857586
24676671
18061164
11058167
12887736
15013753
15158360
22661093
20935672
20511231
17350185
10903137
16112536
27413250
21810609
16984731
16166627
18469854
12881425
24012417
23386688
22105366
8752656
12176740
27371733
22578249
18057724
20351184
10329846
19164127
10542237
11564778
20221401
15517885
19122653
20534538
7876168
27211851
9516466
18996370
8824277
18310089
21104991
25888873
12359431
11327783
20066113
20100571
19703987
19469019
21106671
16960103
18502099
16043358
21996739
20650996
22021035
11120852
12672795
12058956
18483242
22189669
14976218
17495236
11007957
21131967
11975924
27337441
9182853
10963848
17040605
11504280
15756023
10823821
17932106
19966855
20696864
12177065
8679226
9199307
17196927
20457835
21098092
17532054
|
NFKB1
|
IL6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
71.0
|
1.0
|
Omnipath
|
17513725
18061164
12058956
24337575
19124729
15611045
11058167
9523851
15517885
12887736
15158360
7876168
17495236
25549935
17982049
15241416
18243142
9516466
2405250
18996370
8824277
18310089
24664372
15749903
10903137
16112536
14532843
11327783
18942706
11975924
20066113
16984731
10975857
11160296
19703987
22895549
10963848
10469356
22547075
17040605
11459775
17490702
19469019
8247545
11504280
15756023
10569191
10823821
20696864
12907458
19707556
16043358
11035101
12176740
11302724
8679226
8725624
22578249
8752656
17196927
17532054
12727841
18057724
7499267
10329846
9199307
9502421
19164127
11120852
24676671
11098847
|
TXN
|
RRM2
|
â—¼ OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER
|
✅
|
|
8.0
|
1.0
|
Reactome
|
18997010
10884394
2668278
11796141
16756507
9677297
16373698
19176520
|
TXN
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18786561
25609649
7788295
|
CHUK
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
CHUK
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
CHUK
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
17145710
15611276
22110409
19609947
10521409
20863851
20051109
20363318
12767944
26999213
12842894
21903422
19110719
15858576
16382138
22155370
23894194
16046471
15128824
21569639
16846590
8246997
15485852
25341660
15494311
11983155
15980040
15489227
15849198
14636585
23343355
|
CHUK
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
9346484
24911653
20932476
28514442
11971985
16970925
12210728
9346485
17965022
16713569
12486103
9891086
15456791
11057907
20434986
16129692
16260493
21903422
21724995
16286467
14743216
16319058
18949366
10779355
25748427
25852190
12244103
11585904
9751060
15218526
10094049
10837071
9914500
21575199
9721103
25241761
10195894
9689078
15214841
21784860
17561400
21640763
16285893
10733566
16186825
16493424
10022904
12709429
12351658
10968790
12547194
15691841
15620648
15327770
11864612
11460167
14636585
17693255
17072322
9346241
|
CHUK
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
39.0
|
1.0
|
Omnipath
|
12482991
19442713
14743216
15494311
11976329
15489227
16382138
16713569
10022904
10469655
27554194
11158290
11297557
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
IKBKB
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
RELA
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
26596471
27338466
11114294
8413223
20975042
17707233
23383347
11058167
12686724
16433741
23667107
15382119
19122653
24009751
27211851
18566416
15292915
20617571
23056550
12517972
18285351
19843519
22267743
15812237
25161822
22388040
8021507
9878621
14960579
10963848
23195252
11395507
27534992
9058643
15543947
19846753
20696864
8679226
24908318
28389361
27371733
15972680
20336759
10080875
17082635
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
RELA
|
ABCB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18234965
21054339
19763573
12527911
22927901
10026303
|
RELA
|
CYP3A4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19002106
16608838
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
IKBKB
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
135.0
|
1.0
|
Omnipath
|
15280197
17785205
27329558
22110409
22753932
22205033
21765477
15611068
18519641
15858576
25241761
33579825
23536830
28122346
19393267
34556881
24442433
14560022
15192014
21242976
16840782
19609947
33789981
10521409
26826124
21492457
19110719
23303310
16105840
22212641
26587973
34219129
15210811
16046471
11359840
27626700
15128824
28416608
17178723
21674813
17362989
28737909
19377466
15980040
16407239
15849198
20507904
26082493
15557193
34082140
21798539
26267322
29363544
12767944
20224721
26307684
12842894
17108032
26170389
24336331
27315556
31980577
11259436
34380537
20872791
21674474
15465828
15994321
17548605
26603838
16148147
25136068
33914760
26569329
22234699
17012367
14636585
22039465
32123095
15212693
27466442
33883226
15611276
22081069
19197368
17070014
20051109
26693062
14963024
33971703
28381553
33459422
27244888
18544167
18922932
20188669
15485852
20696864
22689577
17982102
20410276
15489227
|
IL1B
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25606026
26999213
22240205
23666959
19197368
25306394
24009751
|
NFKB1
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8413223
17707233
11058167
12686724
16433741
18285351
8021507
9878621
14960579
10963848
9058643
15543947
20696864
8679226
11035101
15972680
20336759
18772363
10080875
17082635
|
IKBKB
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
IKBKB
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
57.0
|
1.0
|
Omnipath
|
31598684
11976329
16713569
10469655
29485707
26999213
12842894
10835356
27187478
27402796
18782567
27554194
12482991
25241761
10022904
15199157
19519322
15489227
19250910
15212693
11158290
11297557
|
ESR1
|
UGT1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10854430
23714156
9773976
12114525
|
ESR1
|
ABCG2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20705611
10342828
23592396
22098950
14973083
15695404
19967559
17878748
24103091
|
AHR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12612060
17392787
10620335
|
AHR
|
UGT1A6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9466822
9762354
19525444
8068691
11368516
19831498
|
AHR
|
CYP1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
15664428
21357676
9783729
17959153
11064004
17785579
19022236
11043581
20595379
19525444
8120057
20705892
16636061
15028720
18989830
18360687
|