Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 HEXA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17893873
H2BC9 CDC25A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KRT20 EIF4E2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CAV1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
HRAS RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTG1 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKACA PLN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 22707725 21108950
HSPA1L TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HRAS FOSL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
ABCB1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 15498565 5217256
IRS1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15003536
CAV1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15976327
FOSL1 ITGB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23319049
CDK5 HTR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 30712943
TUBB4A TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MVD GNB5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GNAI1 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15922020 19703466
PRKACA ACADVL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19889959
H2BC9 PDE5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 PRKACB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRKACG PPP1R1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28553197 7826384
ACTC1 PLCZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ABCG8 ABCG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16870176 5218866
F2RL1 ABCC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
H2BC9 EDN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
F2RL1 ADCY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
H2BC9 ACSL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC14 H2BC9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IRS1 RPTOR â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16354680 19561084 30240640
BRAF RPTOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
PDE5A AIPL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 27173435
HEXA DHRS4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACOT2 ACOT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HSP90AA1 STK11 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
ACTB CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17502619 28734243
CSF1R SOS1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10025673 7520523
EDN1 EDNRA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 10770212 16713569 7509919 23597562
ABL1 JAK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9774693 12130510
PDE5A PRKACA â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
PDE5A PRKACB â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
PDE5A PRKACG â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
NDUFB9 UQCR10 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PKIA PRKACB â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
CAV1 INSR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10598578 31217420
ACTB ACTL6A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
HRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 34591642
HRAS BRAF â—¼   PROXIMITY ✅ 0.87 0.87 mint 30194290
HRAS NF1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ABL1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26603102 25219501
ASH2L RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 31544921 17925232 12482968 16253997 21124902 20305087 21516116 21285357 32296183 21220120 15199122 17178841 16892064 15960974 23870121 23508102 26886794 16878130 31076518 17500065 19556245 19131338 33961781 24981860 16603732 23414517 34079125
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
PRKACG PLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25278000 10198180 26347652
PRKACA KCNK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21357689
ABCG8 ABCG5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12208867 16870176 27144356
SOS1 HRAS â—¼   GTPASE_REACTION ✅ + 0.9 0.9 Signor 23132018
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
INSR IRS1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 7651388
ACTA2 ACTC1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
INSR IRS1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ACSL3 ACSL4 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 22939629 26496610
PKIA PRKACG â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
SOS1 HRAS â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17084389 5219305
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
JAK1 IRS1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11162588 7499365 9492017
ANAPC11 CDC23 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
BRAF HRAS â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
NDUFB9 UQCRFS1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
ABCG5 ABCG8 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
UQCR10 UQCRFS1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
HRAS SOS1 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
INSR IRS1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11781100 25667086 16582879 17167487 7935368 10455177 11606564 7499194 15629149 8662806 8626379
PKIA PRKACA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMA7 PSMD7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
IDH3A IDH3G â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ABL1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12560071 20841568
ABL1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22553782 24974292 29066624 15657060 20841568 28177918
ABL1 CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 19901323 26944284 15689152 19690332 16497976 24975575 19413330 20841568 18083107 19534553 20068231 19700222 9038181 14757045 23348931 11113134 10896159 18691976 28646794 29063113 24600352 12372285 19369195 18794154 15212693
ABL1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15039778 20841568 8112292
ABL1 PSMA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16678104 25620702 20841568
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MAP2K2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12792650 18669648
PRKACA CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 29352269 15703181
ACP1 EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 21538645 12167657
RPTOR PPARGC1A â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RPTOR PPARGC1A â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RPTOR IDH3A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RPTOR PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PRKACA STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11853558 17482548 11297520 17482549 10642527
PRKACA PLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 2544595 12134142 3759968 10988285 12692124 9468536 33897445
JAK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15001544 11591769 8756628 7544789 9305869 11162588 9233603 15592455 7499365 12220227
IDH3A IDH3G â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 10677231 14681455 28098230 33961781 26186194 14555658 26344197
PPARGC1A IDH3A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
HRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NF1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8628317 19777070 26635368 24431436 19718661
SOS1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12628188 10208427 16713569 10913276 23331499 18454158 15507210 10592173 17673906 17496910 26721396 20133692 19141281 23132018 11560935 9447984 9690470 17084389
HRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 7706312 14970219 18567582 12932319 8073291 1386920 23331499 8601312 9154803 18988627 8668348 21779497 19541618 19933846 17563371 18098337 16803888 26165597 24441586 16135787 12917261 15710605 10545207
NGF IRS1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 15099563 16931767 17604717 17764704 19030972 21540285 22421439 22465479 24036369 25071162 28645028 8621421
NGF IRS1 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 15099563 16931767 17604717 17764704 19030972 21540285 22421439 22465479 24036369 25071162 28645028 8621421
INSR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9756945 10598578 12036959 17699617
IRS1 SOS1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8316835 8810325 9832424 8621421 8530377 9852124 9003010
PRKACA IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17360977 12624099
INSR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 10655627 7651388 25472611 1385403 18083107 12220227 23331499 28328746 7504175 19534553 7499194 7537849 7935368 11572799 11781100 10592173 17570479 17575262 18988627 12446583 15629149 10455177 15870194 11416002 12101187 17167487 8530377 8626379 8662806 11606564 2159922 8626723 16020478 16582879
CDK5 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11823425
CDK5 PPP1R1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11013232 16353915 24560149 10604473 21848865 25196634 29082320 21904525 21811441 16040813 24555476 12237154 19465087 29354053 26979514 17194217 11050161 20169176 17535922 14744247 12065642 22820052 18808062 19580849 15464122
GNAI1 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9748257 23109003 15539636 7935349 16460834 11376933
PKIA PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1770951 8027074 7905001
PRKACA ACLY â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19415658 17081983 10653665 17924679 18767875 18088087 18452278 18669648 15302935
PRKACA BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11510412 10931830
PRKACA SNAPIN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15269257 21356520 11283605
PRKACA GSK3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 18691976 8524413 12054501 19413330 11749387 11884598 11035810
PRKACA PPP1R1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11717349 1494946 10604473 15726118 15536496 6319628 6296685 3339428 17194217
PRKACA AANAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11336675 15644438
PRKACA ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7907095 2900138
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
EDN1 EDNRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 90829707 6479761 9082970 7509919 16597412 16713569 23597562 15629009 8440682 7647976 10770212