H3-4
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MAP2K6
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11460167
10882101
|
MYH10
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PSMD4
|
PSMA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
ACTB
|
TRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
BDKRB1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11713280
31160049
|
OPRD1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15082510
31160049
|
DRD3
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15102843
31160049
|
GNAI3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8327893
19703466
|
ACTG1
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
OPRD1
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11259487
31160049
|
UBA52
|
CD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
UBA52
|
H3-4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
UBA52
|
H2BC21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
UBB
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RRAS
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PLCG1
|
FGFR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16844695
10652257
|
TUBB
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SLC25A5
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PRKD1
|
MAP3K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
17496911
17703233
|
MAP2K7
|
MAP3K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11306453
9639556
|
NAMPT
|
ADORA2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6538693
18486613
|
PRKCE
|
PRKD1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0809661105
19011111
|
PSMD4
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
UBE2J2
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GNA14
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
GNAQ
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
GNA11
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
GNA15
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
BDKRB1
|
GNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1645526
11713280
|
CNR1
|
GNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15082510
2165569
|
GNB2
|
ADCY2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1962211
1312225
|
DRD3
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10978845
31160049
|
CNR1
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11168387
31160049
|
GNAI1
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15922020
19703466
|
PRKCE
|
ADCY7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17185372
|
PRKCE
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17185372
|
GNA11
|
GNAQ
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
GNA15
|
GNAQ
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
GNA14
|
GNAQ
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
ADRA1B
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9481484
31160049
|
NMBR
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8026589
31160049
|
EDNRA
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15475516
31160049
|
S1PR3
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10488065
31160049
|
GNA14
|
GNA11
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
GNA11
|
GNA15
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
CNR1
|
GNAO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15082510
31160049
|
DRD2
|
GNAO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1445393
31160049
|
DRD3
|
GNAO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15102843
31160049
|
ERBB4
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
17496910
|
CAMK2D
|
ITPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23019322
|
GPR37
|
WLS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
HRH1
|
WLS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
EPAS1
|
ADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18508787
12099714
|
DPP4
|
NPY
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
21314817
8090457
|
HTR4
|
GPR37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GPR37
|
SLC8A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
HTR4
|
GPR37
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
HTR4
|
GPR37
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GNA14
|
GNA15
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
H3-4
|
ARHGEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
BDKRB1
|
SLC39A14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
H3-4
|
H2AC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC21
|
H3-4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2BC15
|
H3-4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GNAI3
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
P2RY8
|
GNAQ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
RAC2
|
RAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GNA11
|
EDNRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
10789830
|
P2RY8
|
GNAZ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
SLC25A4
|
SLC25A5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
NGFR
|
NTRK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
PSMA3
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
PSMD12
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
ID1
|
PSMD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9235903
17891176
|
GNAI1
|
CNR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28734930
11168387
|
GNAI1
|
GNAI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PSMA3
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
PSMD3
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
PSMD12
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
KLC1
|
KLC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ADM
|
RAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CD4
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10816381
15660419
14592831
|
DPP4
|
ADA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
26209915
34709727
8568233
11772392
|
NTRK1
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
LAT
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
MAP3K1
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
EPAS1
|
ARNT
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
24981860
|
CNR1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15082510
11168387
31160049
|
OPRD1
|
GNAO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15082510
11259487
8393523
|
MAPK8
|
LAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15192708
|
NTRK1
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25921289
9856458
1715690
8384556
10092678
1400471
10708759
|
FGFR2
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15629145
24440983
25241761
7999363
|
NR3C1
|
GZMA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17180578
|
PRKCE
|
PRKD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10092595
12407104
|
GNB2
|
CACNA1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9009193
10692440
11086994
|
S1PR3
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10488065
31160049
|
GRM1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1847995
1320017
12351712
|
NR3C1
|
NPPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1835978
8780246
9171949
|
EDNRA
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
7882989
10789830
|
ADORA1
|
GNAO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16713569
31160049
10521440
|
ADORA1
|
GNAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9166747
16713569
31160049
|
DRD2
|
GNAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9166747
31160049
10384262
|
MAP2K7
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
ERN1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18471544
27009865
|
PDGFA
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
2466336
1374684
9739761
|
EPAS1
|
ARNT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23434853
15192019
16181639
9079689
19845609
23275444
33591636
26160453
19129502
32461361
14668441
24981860
11018023
23796364
|
KLC2
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MRAS
|
AFDN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10446149
|
PSMD3
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
PSMD14
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
ACTB
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
NPPA
|
NPR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
ADCY9
|
GNAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
CNR1
|
GNAI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
GNAI1
|
GNAI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
22939629
33961781
26186194
|
NDUFA11
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
NDUFA11
|
NDUFB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ACTG1
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
8153045
21516116
|
PSMD14
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
UBA52
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CASP9
|
APAF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5221774
9390557
|
PLCG1
|
NTRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12419535
26253177
12074588
10092678
|
FGFR2
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
PSMD4
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
PSMD4
|
PSMD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16990800
22863883
33961781
30479383
22939629
26344197
|
PSMD4
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
LAT
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7544353
9489702
16713569
16467851
16938345
10811803
27221712
24642916
9729044
11368773
|
KLC1
|
KLC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
26496610
22863883
33961781
17332754
22939629
|
MAP2K7
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
APAF1
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
PSMA3
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PSMD13
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD3
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
ARNT
|
EPAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD12
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
APAF1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
17145710
15829969
15024710
9390557
19494828
11113115
10617566
9539746
10364241
10722681
27476169
21060833
19118655
20829884
16977332
10329646
15210107
10393175
16352606
11242052
14555243
10376594
12773388
10206961
19337385
10428850
9488720
19788417
15262985
9922454
21827945
10749135
9651578
19698783
12792650
9837928
11227497
|
MAP2K1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12792650
18669648
|
MAP3K1
|
MAP2K6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17143273
9639556
19369195
9712898
16728640
|
PPP1R12A
|
MYH10
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
CXCR4
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
|
DRD2
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
2898118
1445393
10978845
10384262
31160049
|
ADORA1
|
GNAI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3805010
6305455
6162091
31160049
|
GNAI3
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
8327893
|
GNAI3
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
PLCG1
|
LAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
PLCG1
|
LAT
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
PLCG1
|
LAT
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
LAT
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
27221712
11368773
9489702
12941616
15286727
10811803
23109003
24642916
16938345
11709089
16713569
15219999
16467851
9729044
|
FGFR2
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12601080
17081983
7999363
16038803
1689310
1708307
7682059
15144186
8885868
16126727
15592455
8657103
16153436
24440983
|
NTRK2
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12601080
12419535
17081983
16038803
1689310
1708307
10092678
7682059
15144186
8885868
16126727
15592455
8657103
12074588
16153436
|
NTRK1
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10708759
23331499
1400471
8552402
9856458
21071413
8384556
10092678
25921289
18988627
1715690
|
PRKD1
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19651622
8885868
20068231
1370476
|
NDUFA1
|
NDUFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFB1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFB3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
GZMA
|
NDUFA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11413196
14499263
15607806
16106370
18485875
8432729
|
NDUFS6
|
NDUFA11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB3
|
NDUFA11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB1
|
NDUFA11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB1
|
NDUFA11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB3
|
NDUFA11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS6
|
NDUFA11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
GZMA
|
NDUFA11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11413196
14499263
15607806
16106370
18485875
8432729
|
NDUFB1
|
NDUFB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB1
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB1
|
NDUFB3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB1
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
GZMA
|
NDUFB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11413196
14499263
15607806
16106370
18485875
8432729
|
NDUFB3
|
NDUFS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB3
|
NDUFS6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
GZMA
|
NDUFB3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11413196
14499263
15607806
16106370
18485875
8432729
|
GZMA
|
NDUFS6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11413196
14499263
15607806
16106370
18485875
8432729
|
MAP3K1
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12738796
15170913
15592525
17462996
17496911
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
9379049
9582321
|
MAP3K1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8385802
12048245
8131746
17110930
8034665
8019005
10969079
12456688
|
MAP3K1
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
10713157
19392652
18855897
9379049
26696630
17462996
12947395
18641653
23331499
23850759
12048245
11668179
21133840
21614932
21232017
12738796
9582321
24378531
22903704
11242034
10465784
15592525
17110930
26192618
9312068
17496911
11274345
15170913
|
MAP3K1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12228228
9405400
25241761
10465784
15757900
15299005
14500727
21152872
26538579
|
GLI1
|
ACTA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11001584
17638910
18754008
19081070
22354771
23031257
|
GLI3
|
GLI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12435627
14723851
10075717
16571352
19667090
|
CXCR4
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508237
23109003
17084806
18538863
10644702
16183910
15337520
10506573
|
FGF5
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
838682811876253
16597617
8386828
11876253
25772309
|
PRKCE
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11447289
19615955
16488589
6321473
8321321
12845332
11313945
23564461
12040186
19568798
15567848
14585353
|
FGF22
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
16597617
12591959
8663044
25772309
|
PRKG1
|
IRAG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11309393
10724174
16990611
|
PRKG1
|
PPP1R12A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
19120700
10579722
15194681
10567269
|
PRKG1
|
HRH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
15107581
10101032
|
NGFR
|
NTRK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
8155326
10985348
9099755
8382740
11238898
1850821
7510697
11425862
8356095
25708205
10235685
10490030
1850549
9927421
7616616
1849459
7836442
1280261
|
ADCYAP1
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
8703026
16930633
12488235
10583729
11931347
21350482
10100920
17470806
8253796
|
GRM1
|
GNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1656524
12351712
1320017
1847995
|
GNAI1
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
GNAI1
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9748257
23109003
15539636
7935349
16460834
11376933
|
ADM
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10781016
12565884
15692146
|
ADM2
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21658025
15692146
|
CALCB
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
14722252
9487987
7588285
11033437
2158663
11023820
10342886
15692146
12565884
|
PRKCE
|
GRM5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15894802
|
BDKRB1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12130679
11379050
31160049
11713280
|
NPPA
|
NPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
12547834
29934640
12488235
16713569
8700153
15911069
|
ADA
|
ADORA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9247966
12150791
16713569
18680557
|
MAP2K7
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
12821118
10713157
11489946
17145710
9362518
13130464
18855897
19690332
95141073
24975362
23331499
7839144
21071413
18362184
11062067
21614932
15911620
12738796
18436711
11389443
10506143
11242024
11847100
18669648
16153436
15725726
25241761
18691976
14523011
25284480
16076903
17192257
11390361
15755722
16533805
19369195
9312068
9207092
9733513
12758252
12624093
15212693
11274345
|
MAPK8
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12351702
18337589
9482836
9199329
18669648
|
PIK3R3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8596638
22402981
11733063
25814554
|
RAMP2
|
ADM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8387282
11693189
10217420
9620797
14615490
|
ADM
|
RAMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11693189
30139742
12565884
9620797
|
PRKCG
|
GRM5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15894802
|
VIP
|
SCTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1646711
8390245
|
VIP
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
16930633
12488235
10583729
11931347
|
PRKCG
|
CYTH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10531036
|
RAMP2
|
ADM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8387282
11693189
10217420
9620797
14615490
|
CALCB
|
RAMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11693189
26423127
16531504
9620797
|
ADM2
|
RAMP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21658025
30139743
20596793
32196115
|