Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAPK1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217079 15225643
MAPK1 BCL2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217079 15225643
GABBR1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
KCNQ1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
F2RL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 TPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
GRB2 ACTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NR1H4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 TPM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
DRD3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11384839
SNTA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11551227 11278583
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
ELF4 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19454702 20802152
PARP1 MAPK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
MTNR1A MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18930812
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
MAPK14 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18253836
FOS MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
MAPK3 SOS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK3 PARP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
PIK3R1 GABBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 GABRA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 GNAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
PIK3R1 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PRKCA ATP1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17570479 14976217
CALM1 ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16258073 10075700
CALM1 ATP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6455424 1332771
OPRM1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082510 31160049
ADRA2A GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 1849000
SSTR2 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 1374909
OPRD1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082510 31160049
SSTR1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8145728 31160049
DRD3 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15102843 31160049
OPRK1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082510 31160049
GNAI3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8327893 19703466
OPRD1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259487 31160049
TNNC1 TNNI3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SOS1 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9544989 6547749
SHC1 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
PRKCA SHC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7929214 12052829
SHC1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7537361
SOS1 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9516477 6730883
PLCG1 F2RL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ERBB3 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
PIK3CA FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21239258 1918021
FOS EDN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9588211 16716598
FOS CGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15961508
MAPK11 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA GLRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8294452 17570479
CREB1 ADRA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10520459
CREB1 AGTR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11108142 24244341
CREB1 NTS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7791794
CREB1 AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15089973 9389510
CREB1 ADCYAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16006741 24018543
MAPK11 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11532940 11335727
DRD3 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10978845 31160049
HRH4 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 10973974
OPRM1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12068084 31160049
PTGER3 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 12038972
ADRA2A GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 11732925
CNR1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11168387 31160049
GNAI1 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15922020 19703466
PPP2R5A PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
NTS NLN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 3525564 27496565
ADRA1A ATP6AP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
PIK3CA GNAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
ERBB3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
GNAQ AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219925 17498700
ADRA1B GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9481484 31160049
ADRA1A GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 1334487
GALR2 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 9685625
MTNR1A GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10598579
PTGER1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 17251915
HTR6 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12650852 31160049
HTR2B GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11916537 31160049
GNAQ PLCB2 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
MAPK11 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9776729 11604491
ACTC1 TPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AGT ANPEP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 15687497 17803194
DRD4 ADRA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22723743 1001347
DRD4 ADRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22723743 1001347
DRD4 ADRA1B â—¼   PROXIMITY 2.0 0.8 intact 22723743 1001347
DRD4 ADRB1 â—¼   PROXIMITY 2.0 0.8 intact 22723743 1001347
GABBR2 GABBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218685 16724110
BDKRB2 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CMA1 EDN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9257865
MTNR1A MTNR1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20859254 8087006
TNNC1 TPM1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
AGT AGTR2 â—¼   UP_REGULATES ✅ + 0.81 0.81 Signor 16597412
TPM1 TPM4 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
SHC1 PIK3R1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16219545 5217992
P2RY8 GNAQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
TPM2 TPM4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33961781
EDNRB EDN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16713569 12972292 23597562
GRIA3 GRIA4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACE AGT â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
FPR2 GNAI1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
PPP2R1A PPP2R3A â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
GCGR GNAI1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
GRIA1 GRIK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8288598 10358037
TNNI3 TPM1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
NLN NTS â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF4 FOS â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
GNAQ VIPR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11981043 11812005
GRIK5 GRIK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 8288598 15583001 9466455
CALM3 RYR2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CALM1 CAMK2B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ACE2 AGT â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
AGT AGTR2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ATF2 MAPK11 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PLCG1 SHC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8662733 8155326 10652211
CREM CREB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7809053 16189514 22531917 25609649
TBP CREM â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10409662 16713569
CALM3 SLC9A1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CALM1 KCNQ1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
ADRA1D SNTA1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
SSRP1 PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
TNNI3 TNNT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11904166 12840750 9560191 18986304 9219516
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
TNNT2 TPM1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
TAC1 TACR1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
GNAI1 CNR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28734930 11168387
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIK3R1 SHC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TPM1 TPM2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FOS ATF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 25241761 23661758 1827203 20102225
TNNC1 TNNT2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12840750 9219516 9560191 15542288
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SNTA1 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11551227 11278583
ERBB3 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9756944 24189400 24658140 16729043 11173924
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CALM1 SLC9A1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
GNAQ TBXA2R â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
FOS ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 1828107 25416956 32296183 16511568 23661758 20195357 33961781 1827203 26186194 25609649 20102225
MAPK1 ATP1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15069082 14976217
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
CREM CRH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16451219 15843609 19543827
CALM3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2022671 7685187 8417150
CALM1 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2022671 7685187 8417150
CNR1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15082510 11168387 31160049
MTNR1B GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17215244 31160049
TNNI3 TNNC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11904166 12122471 12840750 15049709 16302972 29997244 12939162 9346285 7957210 33961781 15134451 18986304 12060657
SHC1 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
SHC1 ERBB3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9019162 9756944 24189400 22973453 24658140 16273093 16729043 11546794 8665853 9694850
TBP FOS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8065335 7685215 16055710 16713569
PRKCA ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8206971 7759492
PRKCA GRM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10488094 11007882 12021391
CREB1 LEP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20484458 18787032 23056265
CREB1 GNRH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18599546
CREB1 HCRTR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20156195
MTNR1A GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17215244 31160049
SSTR2 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7914078 16189514 31160049
MTNR1B GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17215244 31160049
PIK3CA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
AGTR1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17498700 31160049 11313903
TSHR GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17891229 32698392 8188646
REN AGT â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 22193701 12045255 12927775
AGT CTSG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6807977 9570564 20889553
CTSG AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11747312 10899625
TPM2 TPM1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 7568216 33961781 26186194 3857586 30021884 22939629
CREM FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21659477 10209256 20008557
CGA LHB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11445554 18431515 10988300
CGA TSHR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8188646 2558651 12045258
CGA TSHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15571461 20181794 12045258
TSHB TSHR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8188646 2558651 12045258
PMCH MCHR2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10421368 11562423 10421367
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
FOS ATF2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 25609649
ERBB3 PIK3R1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
SHC1 SOS1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CALM3 CAMK2B â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
ERBB3 SHC1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CALM1 RYR2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PIK3R1 ERBB3 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
GRIK2 GRIK5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CNR1 GNAI1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
AGT REN â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
GNAI1 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
SNTA1 SCN5A â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 9412493 18591664
CACNA2D1 CACNB1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATF2 MAPK14 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PPP2R1A PPP2R2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
TNNI3 TNNT2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ATP1A1 FXYD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PLCG1 GRB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16713569 7629168 7516467 9020117 21706016 10940929 16038803 9281317
SHC1 SOS1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8631299 10570290 10025673 8235613 8626525 9544989 10675333 10783152 8950973 7559490 19380743 16371368 9344843 7520523 8621459
SOS1 PLCG1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16713569 17474147 9020117 10940929 10913276
TPM1 TPM4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25416956 33961781 26186194 22939629
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8940013 6169950
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5220480 7642581
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
CGA FSHB â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
TNNC1 TNNT2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CALM3 KCNQ1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CALM1 SCN5A â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CALM3 SCN5A â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
TNNC1 TNNI3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12485888 21725358 31980649 9126968 7514169 7744881 8235613 11453982 8662733 8491186 7629070 8940013 10570290 8112292 12213123 11302736 8662998 8195171 7597091 8810340 32062451 9129019 16371368 12149229 10049786 8626525 7650032 8950973 9488479 24189400 15812354 12441060 19380743 26551075 22057045 10477741 28690151 16713569 7516467 9733714 11827484 11964172 7537740 16520382 9019162 8663178 9797459 9032244 12577067 9927207 7524086 8995379 9886492 8294403 7559490 9434624 11792427 7798267 8621719 9541596 15688026 12898421 33961781 11370743 25416956 9544989 22974441 8939605 21706016 9083103 7535773 11505033 9175774 24430869 10080542 9020193 9045692 10356320 15888547 9254595 8561895 11707405 8647288
GABBR1 GABBR2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PPP2R1A PPP2R3B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A PPP2R2D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATF2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
MAPK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10777545 17081983 21098032 9430721 12110590 20068231 19690332 15304344 19413330 10878576 15192015 7737129 18669648 19647037
MAPK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10777545 12110590 20068231 15304344 15192015 19647037
MAPK12 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 15140942 20506250 9029150 21614932 11238375 16393692 10085140 11274345
PRKCA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1661585 9436983 19176525 92095966
MAPK14 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 17081983 18767875 21098032 20506250 26359454 19690332 11060298 19413330 12788955 10085140 22037767 11566021 17079470 19647037 10581204 10777545 7535770 23331499 7839144 19324872 21071413 21614932 20068231 16393692 15304344 17570479 17380123 18988627 7737130 18669648 15187187 9305639 7737129 15140942 602896 11896587 17548358 12110590 7824938 8663524 33893075 12024021 11078583 11971971 9707433 17258390 10821277 19651622 19436832 11259586 27726305 11781825 9430721 27142525 10909971 12118074 15569672 15212693 9753474 11274345 10903740 26987986
MAPK11 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17145710 17081983 20506250 19690332 19413330 17079470 11566021 10085140 17254968 10777545 7535770 7839144 21614932 16393692 15304344 17380123 7737130 15192015 18669648 15187187 15140942 9235954 12110590 17258390 19436832 9155018 9430721 9029150 14734562 11274345
PRKCA BCL2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10677502 10679481 10871288 11323415 16492141 20027184 9115213 9738012
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
PRKCA BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 12039060 9115213 12213578 11323415 17610064 9738012 19117992 24212628 10677502
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
MAPK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9115213 10567572 12039864 10669763 15225643 11323415 21785723 9738012 11337027 10677502 23272207
MAPK14 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 29050237 16714293 19336399 11495898
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
SOS1 GRB2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 16520382 31980649 32062451 8493579 21988832 14679214 7510700 7514169 21706016 10319320 32203420 9872323 9797459 34407391 16906159 10716926 12577067 8810325 7629168 11960376 7664271 8626525 15192046 7629138 11997436 8943292 10207103 8695800 10570290 10025673 8112292 11726515 8816480 20473329 7559490 7773779 9447984 19380743 7642581 7527391 9716598 9344843 10477741 16713569 19323566 7516467 17474147 9569023 8188688 16893902 11964172 9478994 33961781 8479541 28166272 9009162
GRB2 SHC1 â—¼   PROTEIN_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20058876 15253667 25162926 27049728 18669648 17209041 18088087 20068231 11604491 23602949 18701649 23678047 28554535 19415658
MAPK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10197981 8816480 9922370 8626428
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
MAPK1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23597856 26637332 16627622
MAPK12 SNTA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17081983 18669648 20068231 19413330 10212242
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11175347 12356771 15733869 11160957 11532940 7958915 9829964 12235136 16189514 11335727 9687510 8887554 11698596 23532963 8688081 9528766 11018520 11969286 11377386 11909979
MAPK14 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9776729 20068231 11604491 18701649 18669648
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK3 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17018293 12134156 20506250 15547943 7816602 15084594 12697810 8226933 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 26725323 21098038 9604935 11274345
MAPK3 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 7478566 23331499 8816480 7739560 17570479 9922370
NBN PARP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SHC1 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
ERBB3 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 17145710 18803287 16273093 23331499 21278786 21071413 11694521 18988627 10383151 9130710 17496910 11546794 20227043 20007781 24189400 10572067 22439932 9756944 21075308
SHC1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19531499 8662998 7537361 19380743 8621719 16135792 9541596 16219545 16713569 23397142 19889638
PIK3R1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17474147 19531499 25241761
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
CSH1 PRLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 10966654
FOS CRH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8793851 1663213 17895291 7894465
CRH CRHR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8536644 8243338 23504413 11123370
CALM3 GRM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10488094 11953448 12021391 32196115
CALM1 GRM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15494036 10488094 11953448 12021391
MTNR1A GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10598579 17145710 17215244 31160049
ADORA1 GNAI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3805010 6305455 6162091 31160049
GNAI3 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933 8327893
GNAI3 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
SHC1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
ERBB3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9694850 9756944 16273093 24189400 8026468 24658140 9590694 16189514 16729043
PRKCA SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12052829 19651622 18669648 17924679
SHC1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 9544989 8631299 8621483 8950973 10891441 10783152 9278309 17673906 9344843 8294403 8021500 10025673 7520523 12955078 12577067 9199344 19531499 7760801 10570290 19380743 8235613 10675333 8114695
PRKCA PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 2820980 8885868 10592173 1370476
PLCG1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15953601 12084069 7629168 9020117 16713569 10913276 17474147 10940929
CREM FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17056544 21757709 17185632 15322221
FOS NTS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7675173 7791794 8182549 7914659 7804603
FOS FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23178797 18653705 23770611 21659477 23275456 21292826
PRKCA ADRA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9353340 17570479
PRKCA NR1H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18755856 27571290
PRKCA GRIA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12609872 14973229 28377502 12805550 25533481 23374940 18305116 27669991 24367106 9407043 8663994 19503082
PRKCA TNNI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11904166 12551921 21927813 9346285 7592712 11121119 24466001 12044157 25771144 2584239 14596793 15769444 15134451 8543035 8798526
PRKCA ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8383119 8900209 9366262 7938004 9268695
PRKCA TBXA2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 16956790 18578522 10827090 24490858 11516166 7961988 9054415 9915793 17466390 11015313 9560198 15100160 11504827 12370102 14530262
PRKCA GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12147342 11306676 8940188
PRKCA ATP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9824678 11779484 1827443
PRKCA GRIA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10366608 12536214
CREB1 CGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11518798 10341006 15637148 11014230 21986493
CREB1 GRIN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15774772 16313514 23012887 22364833
CREB1 TRH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18427988 20136691 9827656 11134186 12113951
CREB1 FSHB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18550775 8592521 21986493 23393127 20008557
CREB1 REN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22645148 15857826 8914017 8999953 9247737 8645191 22628303 8408633 11116131
CAMK2B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CREM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22531917 16189514 7809053 1847666
ADCYAP1 VIPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 8791009 16930633 11897681 12429744 12488235 11931347 9928018
ADCYAP1 ADCYAP1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 8703026 16930633 12488235 10583729 11931347 21350482 10100920 17470806 8253796
AGT ACE â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 6269175 2846041 1848554 10536878 2558510 12540854 3017438 6270633 1668266 1851160
ACE AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11076943 10969042 23056909 15283675
GNAI1 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI1 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9748257 23109003 15539636 7935349 16460834 11376933
REN ATP6AP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1204525512045250 12045255
PIK3CA TPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16094730
OPRM1 GNAQ â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
CHRM1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3110621 1341877 8576109 31160049
TBXA2R GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23962128 20590159 15134434 12726995 12193606 9152406 15782186 21940795 31160049 12399457
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15283675 10969042 10924499 11815627
ACE2 AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969042 11815627
AGT CMA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11502696 10899625 6807977 2266130
REN AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16816138 12045255 20927107
AGT REN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32201502 12045255 20927107
AGT MAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1282979212829790 12829792
AGT AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12006574 21464395 10193788 10993080 16189514 15930094 9797979 16597412 17346243
AGT AGTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 2775266 21464395 8315512 21542804 17138938 8185599 15930094 9797979 8242249 7850406
TAC1 TACR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 7557266 9190866 1311270 8985159 11786503 12548712 8702757 15265501 23597562
CAMK2B GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12147342 11306676 16436603 8940188
PTH1R PTH2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 12559132 3616618 6950381 12098667 8732687 8386612 8397094 8770894 8082781 7797535
PTH2 PTH1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 10854439 11159842
TSHB TSHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 2558651 20181794 12045258 15571461
KNG1 BDKRB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18127230 3366244 8063797 1314587
KNG1 PRCP â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 14996700 12123826 11830581 8344943
KNG1 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9203620 8063797 8302267 28966616
EDN1 EDNRB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 1710450 1719979 8440682 2649896
EDN1 EDNRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12972292 16597412 16713569 15629009 8440682
RLN3 RXFP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17606621 25761609 18582868 14522967 27888281 15367576 15525639 31780677
RLN3 RXFP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17351017 25761609 24615237 20159943 24641548 15367576 27245781 18434306 14522968 22257012
TAC4 TACR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11786503 11062498 15224188
UCN3 CRHR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11416224 11329063 15450949
SPX GALR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31730796 30305242 24517231
SPX GALR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30305242 24517231
PMCH MCHR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 11416225 10471841 11478907 11404457 11274220 11839762
TRH TRHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 27515033 2175902 15117874 9794253
GALP GALR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9832121 983212115944009 15944009
GALP GALR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9832121 20880399 10601261 15944009 23233848