Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 TPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
SH3GLB1 CIDEB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APOA4 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ANXA2 PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10077593
ESR1 SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21820658 23192982
HNF1A ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11522780
ABCG8 ABCG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16870176 5218866
APOA1 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNF1A CYP27A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11406622 10528998
VDAC2 LRP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VDAC3 VDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SH3GLB1 APOH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VDAC3 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APOC2 LPL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10727238 11579204
ESR1 RBBP6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20184719 31527615
CDC42 VAPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
VDAC3 APOE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 TPM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
ESR1 VDAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
ESR1 VAPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
APOH P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32807901 18624398
LIPC ATP4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VDAC1 APOE â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
VDAC1 VDAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 22939629 29128334
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
APOA1 APOB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28183703 7592581 19164805
APOA1 APOA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10722751 24981860 3104518
LDLR MYLIP â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
GRB2 RBBP6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20936779 21706016
APOA1 APOC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15174051 11991719
LRP2 APOE â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11421580 7768901 16713569
VAPA VDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26344197 26496610
LRP2 APOH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9727058 16713569
VAPA VDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 26344197 26496610
NPC1 NPC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20674861 27238017
VDAC2 VDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31536960 22939629 30021884
LRPAP1 SORT1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
APOA1 LCAT â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PLTP APOA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 9469594
LDLR APOB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24447298 12031600
APOA1 PLTP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11854286 9469594
LRP1 LRPAP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ANXA2 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 12577067 7510700 9565634 19380743
LRP8 APOE â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12950167 8626535 12167620 32814053
LDLR APOE â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24447298 12036962 20030366
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
APOA1 ABCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12084722 30458687 27017521
VDAC1 VDAC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31536960 22939629 29128334 30021884
GEM ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LRP1 APOE â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 2779654 11421580 20030366 15182176
F10 APOH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9058203 8460120 9596664
PLG APOH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8460120 9596664
VAPA VAPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19515777 16227268 9920726 26496610 33961781 26186194 34079125
PCSK9 LDLR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18250299 22081141 25613181 18753623 17435765 23085658
MYLIP LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30896554 26666640 23382078
ABCG8 ABCG5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12208867 16870176 27144356
LCAT APOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 4335615 15654758 16189514 1644835 10026251 10222237 1587806 17676061 3104518
HNF1A APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15933209 1545795
HNF1A APOH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17854747 14984368
NPC1 NPC2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
LDLRAP1 LRP2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
ABCG5 ABCG8 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
LDLR PCSK9 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
LRPAP1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 10747918 1718973 1374383 14596620 20030366
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
LRP2 LDLRAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 14528014 23836931 7768901 8710919 8706697
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
APOE LRP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626535 12167620 12950167 16504486
APOE LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12036960 24447298 31677479 20030366 12036962 15840700 11327878
ESR1 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11013347 18005483 9535920 17532863 23293065
PF4 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1198621511986210 11986215
PCSK9 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22081141 29209441 17435765 25613181 23085658 18753623 18250299
APOB LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12031600 24447298 11986215 15840700 1132787812031600 11327878
APOA1 ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 30458687 12084722 12869555 22271762 27100352
APOA1 LCAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 1587806 10222237 10026251 19860440 16189514 15654758 4335615 17676061 1644835
HNF1A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15933209 10403849