Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 ATAD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22771493
ATAD2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17998543
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
E2F2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
E2F3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ATAD2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19843847
E2F4 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799066
E2F4 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
ATAD2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19318566
NCOA3 ATAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0705814104 17998543
NCOA3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
NCOA3 E2F1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16938873 15169882 16648476
E2F1 E2F3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 35140242 24981860 20106982
DOT1L HIST2H4B â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4C â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4D â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4B â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4I â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST2H4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4F â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4L â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4J â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4K â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4E â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST4H4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DOT1L HIST1H4H â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ATAD2 HIST2H4B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4H â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4E â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4L â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4I â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4F â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4D â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4K â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST1H4J â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATAD2 HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4J HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4K HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4E HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4D HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H4B HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H4A HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4H HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4I HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4L HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4B HIST3H3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4F HIST2H4B â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HIST1H4F HIST3H3 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
ATAD2 HIST1H4C â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST3H3 HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ATAD2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25640309 17998543 31527615
E2F4 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14576826 10208422
E2F1 NCOA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16916939 23660594
E2F3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
E2F1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15240700 12389032 18319725
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
E2F4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11564866 12150994 18319725
E2F4 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 12789259 20946668
NCOA3 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26153859 20392877 15383283 14766010 25728767 21182203 15145444 18484708 11376110 14966289 9346901 20181721 26166704 16331275 28844863 11389589 11050174 12630920 19491275 17158759 23403292 12714702 17646391 9192892 11353774 16923966 18645020 16713569 30418174 10490106 9765300 12554772 26487511
NCOA3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10965917 17108143 19305643
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
HIST1H4C HIST3H3 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
AR NCOA3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
E2F3 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576826 7958836 12063292
E2F1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21966451 17178887 22508987 21099110 21099103
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24573694 17132729 17699159 11689553 12757710
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15367674 12695333
E2F4 E2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 21247883 9149906 15718499
TRIM25 CASP8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
CASP8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17170703 9535906 16713569
ATAD2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17998543 25640309
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
NCOA3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14966121 11747336 15563469 16713569 10965917 21047772
H3C2 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799