Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CENPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ESR1 ACKR3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23352615 18414489
AGTR1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
USF1 APC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11241666
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ATP5PO ATP5F1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATP5PD ATP5F1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APH1A APH1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 16252010 16630834
APH1A APH1B â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 16252010 16630834
AP2B1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
ALYREF AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18562279 0802533105
AKT1 ACOT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33148467
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
ESR1 SLC38A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056967 18414489
ACTL6B COQ9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ATP5PF ATP5PD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATP5F1E ATP5F1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APC AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20936779
ESR1 ACAD9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
VDAC1 AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 29128334
ESR1 STOM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26487511 31527615
AP2M1 APC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ACAD9 PDK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 29568061 32877691
ATG14 ULK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ADSL ATIC â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
AKT1 ARNT â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15833858 28628118 28205554
ESR1 DNM1L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19805454 21217774
AP2A1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26344197
AKR1C1 AKR1C3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AKR1C3 AKR1C4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AP2A2 AP2B1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12086608 16189514 33961781 34079125 26344197
AKT1 PDK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27166089 27505672 34278744
PDHA1 PDK1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ACTR1A ACTR1B â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ALDOA ALDOC â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
ULK1 ATG13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27617292 32543267 32668203 23524951 25686248 33450483 20562859 25126726 29196462 18936157 19597335 21460634 23392225 26018823 33499712 32707033 27203176 33422265 30853401 21460630
AP2S1 AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12086608 16189514 33961781 34079125 26344197
AHR ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15837795 19460354 12612060 27420286 17392787 10620335 9611253
BLK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787943 11847100 16076903
AP2B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12086608 16189514 16713569 24189400 33961781 19380743 26186194 30021884 34079125 26344197
APAF1 APIP â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 15262985 16977332 19788417
APAF1 APIP â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 15262985 16977332 19788417
RPS6KA5 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15192015 9873047
RPS6KA5 ACTG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ACTG1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PDK1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9512493
ESR1 AGL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 APRT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ACTR1B MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 ATP5PF â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ULK1 ATG13 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 19211835
ALDOA ALDOB â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 33961781 21988832
ULK1 ATG13 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 8428476 23392225
TOMM20 TOMM22 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
ATG13 ULK1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
AP2S1 AP2A2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 26344197
ACTR10 ACTR1B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ALDOA ALDOC â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 25416956 31536960 25910212 26496610 22863883 33961781 26186194 22939629 26344197
AHR ARNT â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
AP2A2 AP2B1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARNT AHR â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8065341 28514442 11768231 9704006 11259609 7488247 19380484 20006590 22138065 11025203 10617682 23477502 9887096 31675361 12024042 12139968 11551916 17392787 18096572 8384309 10619402 7628454 19390533 26350169 8631989 8621524 10671489 33961781 10395741 8619634
ACTR10 ACTR1A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ACAD9 NDUFS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
APIP APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15262985
ULK1 ATG13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15197469 19225151 21460630 18936157 27932573 19287211 19597335 27390127 27387056 27203176 25686248 26018823 20562859 23524951 33450483 26687599 19211835 23392225 26138443 25126726
AIFM1 NDUFA4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
NDUFA4 NDUFS3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
AIFM1 NDUFA4 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
NDUFA4 NDUFS3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
ACAD9 NDUFA4 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
AIFM1 NDUFA4 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFS3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFS3 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFS3 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
ACAD9 NDUFS3 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
MT-ATP6 MT-ATP8 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 10838049 11410595 11744738 12110673 14701807 14757859 18953340 22841746
MT-ATP6 MT-ATP8 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 10838049 11410595 11744738 12110673 14701807 14757859 18953340 22841746
ULK1 ATG14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27938392 29371398 30397185 23685627 29313410
AKT1 SLC38A9 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17517883 17277771 18372248 12524439 17386266
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 ALYREF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18562279
PDHA1 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 22195962 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
ESR1 CAV2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12711000 12138116 18414489
AKT2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11139588 11432835 11507039 9528769 7838153
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
ARNT AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8621524 8384309 9887096 20006590 10395741 18096572 12024042 7628454 9704006 19380484 17823304 11259609 19390533 22138065 8631989 8619634 8065341 11768231 7488247