Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HDAC1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17980157 18319725
E2F1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9368006
E2F1 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15867357
E2F1 DIRAS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16158053 18319725
ING2 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218757 16782091
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20339243 21467818
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
ING2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20574448
KDM1A MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RELA KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19208907 23423566
SNAI1 KDM1A â—¼   COLOCALIZATION 2.0 0.8 intact 7903691 20389281
RIF1 BRMS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SINHCAF NMI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HDAC1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20609221 22422937
KLF16 SIN3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438660 12036432
RELA BRMS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21765477 19165610
RELA DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23457487 24025864
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
NFKB1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19027835
YWHAE HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10737771 5212359
YWHAE ING1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8007401 16581770
DNMT1 EEF1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
EEF1A1 BRMS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GOLGB1 BRMS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HDAC3 KDM1A â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
ZN704 ING2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FA60A ING2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAD3 ING2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ING2 SIN3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ING2 BRMS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BRMS1 HDAC2 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
FA60A HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FA60A SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SIN3B SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
ZN704 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAD3 NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 7694229 8255759
YWHAE HDAC4 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 8005698 11504882
FA60A BRMS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN704 BRMS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAD3 BRMS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAD1 BRMS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ZN704 SAP30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAD3 SAP30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FA60A ING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FA60A SIN3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FA60A SDS3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAD3 SDS3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN704 SDS3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FA60A ARI4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN704 ARI4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ING2 SAP30 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EP300 ING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 12015309
KDM1A NMI â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23455924 21516116 25416956
ARI4A RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11283269 28514442 26186194 33961781
RBBP7 SDS3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HDAC4 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17011572 10220385 17210713
PRPS1 BRMS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RBBP4 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
SAP30 SDS3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 24981860
SAP30 FA60A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
PRPS1 ELF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MAD1 SDS3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MAD1 ARI4A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BRMS1 SUDS3 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
HDAC2 SNAI1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SNAI1 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28296173 25314079 32494626
EP300 ING2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16024799 16782091
HDAC1 ARI4A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11283269 10490602 23752268 28514442 26496610 33961781
ARI4A SIN3A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11283269 21148318 26344197 33961781
SIN3A BRMS1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15451426 21258344 23390556 14581478
SIN3A ING1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11118440 15451426 33961781 11784859
ARI4A BRMS1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18211900 33961781 16919237 14581478
RBBP4 ING1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 33961781 11118440 15451426 11784859
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SNAI1 HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25314079 21685935
ELF1 NFKB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9094628 7862168
SAP30 ARI4A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11283269 21148318 26496610 33961781
HDAC1 SAP130 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ING1 RBBP7 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ING2 RBBP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16387653 33961781
HDAC4 RBBP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31040226 10220385
BRMS1 SDS3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16919237 14581478
SAP30 MAD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11101889 7889570
ING2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16387653 33961781
ING2 SDS3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16387653 33961781
ING2 ARI4A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16387653 33961781
ING2 SAP30 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16387653 33961781 26496610
RBBP7 SIN3B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194
RBBP7 FA60A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 27705803
HDAC3 RBBP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11777905 16189514 11470869
KLF9 SIN3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 11438660
SIN3A MAD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9184233 33961781 28514442
FA60A RBBP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
KDM1A SNAI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARID4A HDAC1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RBBP7 SAP30 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC1 SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC3 RELA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RBBP4 SAP30 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
E2F1 SKP2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
E2F1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10734134 9468140 17980157 26468294 9468139
SKP2 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22770219 18243116 26593157
HDAC3 KDM1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23752268 21258344 21670149
BRMS1 RBBP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27705803 33961781 26186194 14581478 15451426
RBBP7 ING1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 26186194 15451426 11784859
SNAI1 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21685935 25314079 20534591 14673164 34026424
BRMS1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23752268 17000776 16919237 26496610 21258344 33961781 14581478 15451426
HDAC1 FA60A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23752268 33961781 26496610
BRMS1 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23752268 16919237 21258344 14581478 15451426
HDAC2 MAD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9150134 11101889
HDAC2 ING1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26949739 33961781 11118440 15451426 11784859
HDAC5 HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10869435 10220385 11466315 11931768 11804585 21081666
BRMS1 SMCE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25416956 16919237
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC2 SAP30 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ARID4A SIN3A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC4 YWHAE â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CSNK2A1 HDAC2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ING2 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 18193082 16728974 16387653 33961781
ING2 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16387653 33961781 26186194
HDAC1 KDM1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16079794 19703393 21258344 34050636 11102443 27183383 16140033 21937684 12032298 26496610 22143567 19497860 11171972 17634443 12493763 20856864 20585571 31130994 21670149 26344197 23752268 32882276 17687328 33961781 24981860 28667074
SNAI1 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21685935 26794444 25314079 20562920 23011797 14673164 34026424
BRMS1 NMI â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25416956 30217970 16919237
SDS3 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 11909966 26949739 26496610 33961781 26186194 12724404
ING1 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 18193082 16713569 26496610 33961781 12015309 11118440 15451426 11784859
SDS3 HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 12724404 26949739 24981860
HDAC2 DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23708667 17967891 21670149 10888872
HDAC2 SIN3B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15935060 26949739 21258344 24981860 16464847
HDAC5 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
METTL3 WTAP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
SKP2 E2F1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12097298 17471231 23868976 27720894 16170383 10559858
E2F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24502362 17575144 15867357
E2F1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24755270
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19276347 21625432
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
ING2 SIN3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20676127 16728974 16387653 33961781
SNAI1 KDM1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25639869 20562920 23011797 33961781 26186194 20389281 21300290
KDM1A HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 32882276 19703393 9804427 12032298 20164337 28667074 26949739 34031383 21258344 26344197 34050636 21670149 24981860 11102443 12493763 16079794 21937684
RBBP4 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17255935 27705803 22863883 33961781 24981860 26186194 15451426 22939629 26344197
SAP30 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11283269 28514442 9651585 9790534 10444591 26496610 27705803 33961781 26186194 15451426 11784859
SIN3A RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9651585 17255935 27705803 33961781 24981860 26186194 12453419 15451426 11784859
RELA SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18477483 19538137 17665043
CSNK2A1 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19923321
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
HDAC1 SIN3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 11959842 20585571 10357820 15935060 10444591 26496610 33961781 11102443 24951594 26344197
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
HDAC3 HDAC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 10220385 10869435 11466315 11804585 17956988 27684187 18558095
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
HDAC3 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16528103 18241676
RBBP4 SIN3A â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
KLF16 SIN3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12036432 11438660 22203677 35140242
SIN3A RBBP4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9651585 11118440 9150133 27705803 21258344 33961781 24981860 12943729 12453419 11602581 15451426 9150135
SIN3A MAD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15235594 20547842 28514442 11106735 33961781 26186194 29028833 7889570
SPOP CUL3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22911784 21577200 21988832 19256485 28216678 29160310 25011449 30244836 16524876 22013077 22632832 33961781 25278611 19261606 31559706
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
CSNK2A1 BRMS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 26980766
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
SAP30 ING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 26496610 33961781 11118440 15451426 11784859
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP7 SIN3A â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
BRMS1 HDAC1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HDAC2 ING1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HDAC1 SUDS3 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 SAP30 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC1 ING2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ARID4B SIN3A â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
RBBP7 SIN3B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
SAP30 SIN3A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
ING2 SIN3A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HDAC3 HDAC4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HDAC3 HDAC5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ING1 SIN3A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
BRMS1 SIN3A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
SAP30 SIN3B â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 26496610 10444591 24981860
SIN3B SUDS3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
HDAC1 ING1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
SAP30 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11390640 16820529 10444591 21258344 9651585 9885572 15235594 26496610 11283269 18193082 11784859 23752268 16713569 9790534 33961781 12788099 11118440 15451426
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
RBBP4 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 9520398 19703393 31435636 9150133 10444591 21258344 12943729 11102443 9885572 27068747 10471499 26496610 34518534 20127688 11171972 10734134 11470869 20585571 10220385 12091390 17643391 21670149 11602581 17827154 22939629 9150135 23752268 16713569 9790534 27705803 19686092 24981860 33961781 11302704 11118440 15451426 12920132 26344197
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
HDAC2 SAP30 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11283269 9651585 16713569 9790534 20388487 16820529 10444591 26496610 21258344 33961781 24981860 15451426 9885572 11784859
SIN3A SAP30 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11283269 11390640 9651585 9790534 16820529 9702189 10444591 21676866 26496610 21258344 33961781 24981860 12453419 11118440 15451426 12724404 11784859
SIN3A SDS3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11909966 33961781 24981860 26186194 12724404
SAP30 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11283269 16713569 15451426 9790534 10444591 27705803 33961781 24981860 9651585 11784859
SDS3 SIN3B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11909966 33961781 24981860 26186194
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MXD1 SIN3A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HDAC2 RBBP4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31435636 21258344 12943729 9885572 34518534 12493763 12091390 21670149 17827154 22939629 16713569 9804427 20388487 27705803 33961781 24981860 11302704 15451426 26344197
SIN3A SUDS3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL3 SPOP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
E2F1 SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16331253 23352642 22372491 24574749 20424123 17471231 23348237 17483325
E2F1 DIRAS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16158053 17230502 16757345 16638845
CREBBP E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10753885 15126619 12748276 15123636 8932363
ING2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16782091 16024799
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
NFKB1 HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17724475 21725609 23178297 23572150
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
SNAI1 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
SNAI1 HDAC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
SNAI1 HDAC1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
ING1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 15451426 20574448
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
CSNK2A1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 19007248 16565220 20166139 17081983 20230923 25609639 19413330 19415658 20388487 20068231 18452278 18669648 18691976 17287340 12176973 19651622 12082111 19691289 24526703 18510355 18212344
HDAC3 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
CSNK2A1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17081983 15805470 26663086 27798112 18452278 26356530
HDAC3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11533489 16189514 12419806
SPOP CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21988832 23331499 19256485 28216678 21577200 25011449 34599168 22911784 15897469 22013077 16524876 19261606 25278611
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163