Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AP1B1 CLTA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8909539 11050117
IGF2R GGA3 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
M6PR GGA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11387475 5214102
ESR1 CTSD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6771293
CTSL ACE2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 22816037 19321428
AGT CPA3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2443571 2708524
AGT ANPEP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 15687497 17803194
LTB4R2 CTSA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AGT AGTR2 â—¼   UP_REGULATES ✅ + 0.81 0.81 Signor 16597412
IDS AP3M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
AP3M1 AP3B2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M1 AP3M2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M2 AP3B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M2 AP3D1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP4S1 AP4B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
AP1G2 AP1S1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16713569 9733768
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 VAPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
NPC1 LAMP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33144569
AP3S1 AP3M2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M2 AP3S2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SFXN5 LAMP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARSG SUMF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GNS SUMF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACE AGT â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ATP6V0B ATP6V1H â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
IGF2R GGA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5214130 11390366
RHOC RHOA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781 31980649
ARSA SUMF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ARSA GALNS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IDS PPT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IDS SUMF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 15962010 33961781 26186194
IDS GALNS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AP1B1 AP1G2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
AP1G1 CLTC â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ATP6AP1 ATP6V0A2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ATP6V0D1 ATP6V1H â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
GGA2 GGA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14638859 31076515
AP3B2 AP3D1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
AP3B2 AP3S1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 9118953 33961781
ARSA GALNS â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
AP1M2 AP1S1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ATP6V0D1 TCIRG1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ACE2 AGT â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
AGT AGTR2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
NCOA7 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11971969 9259327
AP1M2 AP1S2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ATP6V0A2 ATP6V0C â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
GGA1 GGA2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ATP6V0D2 TCIRG1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
ATP6AP1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
AP4M1 AP4B1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10436028 33961781
ATP6AP2 TCIRG1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
AP3S1 AP3M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781
AP3B1 AP3M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781 26344197
AP3S2 AP3M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 9182526
AP3M1 AP3D1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23144738 22863883 33961781 26344197
AP3B1 AP3S2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 9182526
AP3D1 AP3S2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15469849 9182526
AP4E1 AP4S1 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
AP4M1 AP4E1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10436028 33961781 26496610
AP4E1 AP4S1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10436028 33961781 26496610
NPC1 NPC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20674861 27238017
ATP6V0A2 ATP6V0D2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AP1G2 AP1S2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ATP6V0A1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AP3B2 AP3M1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AP3B1 AP3M2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
AP4B1 AP4E1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CLTB CLTCL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ATP6AP2 ATP6V0C â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
AP1B1 AP1G2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 33961781
ATP6V0C ATP6V0D1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ATP6AP2 ATP6V0A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AP3D1 AP3S2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
AP3B2 AP3S1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
GGA1 GGA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14638859 33961781 28514442
AP4B1 AP4E1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10436028 26496610 11409905 32073997 33961781
AP1M2 AP1G2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
AP1M2 AP1S2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
AP1M2 AP1S3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
HEXA HEXB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16698036 33961781
CLTC GGA1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
REN AGT â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 22193701 12045255 12927775
AGT MME â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15283675 17704566 14747736
AGT CTSG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6807977 9570564 20889553
CTSG AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11747312 10899625
AP1B1 AP1M2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ATP6AP2 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CLTA CLTCL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
AP1M2 AP1S1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 28514442 10535737 16189514 33961781 26186194
ATP6AP2 ATP6V0A1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
AP3D1 AP3M2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ATP6AP2 ATP6V0D2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
AP3B1 AP3D1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 22863883 15469849 22939629 26344197
ATP6AP1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V0A1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V0D2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
AP1B1 AP1S3 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 23415225 33961781
GGA3 M6PR â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ACE RHOC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NPC1 NPC2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ATP6V0B ATP6V0C â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
AGT REN â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ATP6V0C ATP6V1H â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
AP1B1 AP1S2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 26496610 33961781 22939629 26344197
AP3B1 AP3S1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22863883 33961781 22939629 26344197
AP1M1 AP1S2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 26496610 33961781 22939629 26344197
HEXA HEXB â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
AP1G1 IGF2R â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ACE RHOA â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
AP1M1 AP1S2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AP1M1 AP1S1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AP1B1 AP1M1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
GGA1 SORT1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
AP1B1 AP1S2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP1B1 AP1S1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP3B1 AP3S1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
AP1G1 AP1B1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10535737 10747088 9733768 7593184 23415225 11409905 33961781 22939629 26344197
AP1B1 AP1M1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7593184 22939629 33961781 26344197
AP1B1 AP1S1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 33961781 24843023 26344197
AP3S1 AP3D1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 15469849 23144738 22863883 33961781 26344197
AP1M2 AP1G1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 10535737 16189514 33961781 26186194 26344197
AP1G1 AP1M1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10535737 10747088 7593184 22939629 26344197
AP1G2 AP1S2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16713569 9733768 26496610 33961781
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
AP1B1 AP1G1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
AP1M2 AP1B1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 10535737 33961781 26186194 26344197
ATP6AP1 ATP6AP2 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
AP1G1 AP1M2 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3D1 AP3S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
AP1G1 AP1S1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
AP1G1 AP1M1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
AP1G1 AP1S2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
AP1G1 AP1S1 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 10535737 16189514 10747088 9733768 7593184 15758025 22939629 26344197
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
AP1G1 AP1S2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 29892012 16189514 25416956 9733768 26496610 33961781 22939629 26344197
GGA2 IGF2R â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GGA3 IGF2R â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GGA1 IGF2R â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
AP1S1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1S2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
ESR1 CTSD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7786196 19383337 19569049 16219765 8524236 9731700 11165043 18414489 2350335 10037443 8195246
AGT ACE â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 6269175 2846041 1848554 10536878 2558510 12540854 3017438 6270633 1668266 1851160
ACE AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11076943 10969042 23056909 15283675
REN ATP6AP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1204525512045250 12045255
AP1G1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15283675 10969042 10924499 11815627
ACE2 AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969042 11815627
HEXA GM2A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2970528 1720305 527942 16698036 2971395
AGT CMA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11502696 10899625 6807977 2266130
REN AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16816138 12045255 20927107
AGT REN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32201502 12045255 20927107
AGT MAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1282979212829790 12829792
AGT AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12006574 21464395 10193788 10993080 16189514 15930094 9797979 16597412 17346243
AGT AGTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 2775266 21464395 8315512 21542804 17138938 8185599 15930094 9797979 8242249 7850406
HEXB GM2A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2970528 1720305 527942 16698036 2971395