PECAM1
|
FANCG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TNF
|
ICAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21474822
22846676
|
HBB
|
HBA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HBB
|
HBA2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
ITGB2
|
ITGAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19161977
21270398
|
ITGB2
|
ITGAL
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19161977
21270398
|
CXCL8
|
ACKR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8248172
12956774
|
TLR4
|
CD36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20037584
7685021
|
GATA1
|
PECAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8955189
9028949
|
SDC2
|
SDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
SDC1
|
SDC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18093920
0708909105
|
MYD88
|
TLR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
MYD88
|
TLR9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15107846
21911421
|
ICAM1
|
ITGB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
TGFB2
|
TGFB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27684187
11483955
33961781
11157754
|
HBA2
|
HBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
ITGAL
|
ITGB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
MYD88
|
TLR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17126326
15107846
16482509
16293622
29990310
|
GATA1
|
KLF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20564185
8195185
18487511
|
MET
|
HGF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17804794
18593464
15167892
1846706
28628118
1655405
19433454
20624990
18495663
16537482
22897854
28205554
17981115
8380735
|
IL1B
|
MYD88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17507369
17890055
9430229
|
EIF2B1
|
EIF2B3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
17353931
|
EIF2B1
|
EIF2B2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10805739
21795329
9446619
|
THBS1
|
TGFB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22943793
8349738
21900405
|
THBS1
|
TGFB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22943793
8349738
21900405
|
GATA1
|
GYPB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1396593
8634425
|
MYD88
|
TLR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
CD40
|
CD40LG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
TLR4
|
MYD88
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17126326
15107846
10952994
17258210
18221795
20048342
15728506
33052227
12646618
11743586
21911421
21829704
|
ICAM1
|
ITGAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
EIF2B2
|
EIF2B5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
EIF2B2
|
EIF2B3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ATR
|
FANCG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
70.0
|
1.0
|
ACSN
|
11438669
11877377
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
15459660
15485915
15798197
15867354
16332722
16337602
16540648
16697054
16713580
16731533
16885023
17035102
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18157158
18448394
18469862
18472307
18511906
18543256
18550849
18677104
18716619
18756267
18931676
18995830
19004803
19217833
19225445
19258535
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
19847258
20019063
20051983
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
9488723
9858600
|
ATR
|
FANCG
|
â—¼ UP_REGULATES
|
✅
|
+
|
70.0
|
1.0
|
ACSN
|
11438669
11877377
12239151
12466554
12535671
12972610
14657033
14988723
15136767
15189446
15459660
15485915
15798197
15867354
16332722
16337602
16540648
16697054
16713580
16731533
16885023
17035102
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18157158
18448394
18469862
18472307
18511906
18543256
18550849
18677104
18716619
18756267
18931676
18995830
19004803
19217833
19225445
19258535
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
19847258
20019063
20051983
20832754
21948210
22266823
22615860
22657828
23253856
23444773
24089143
24095737
8020957
9488723
9858600
|
ATR
|
FANCG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
22615860
18677104
19622404
15798197
19793801
12972610
23253856
15136767
19327579
19282663
17116885
17582221
14988723
17384638
24095737
18931676
8020957
22266823
24089143
20832754
15459660
23444773
19772495
19847258
17296725
11877377
17102137
18550849
21948210
22657828
16697054
19686080
12535671
|
IFNG
|
ICAM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IL18
|
ICAM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
ICAM1
|
TUBGCP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10591186
11592085
12413632
12616499
14662834
15356110
1673988
19454690
19965656
20231889
2150484
23364881
23886063
24343663
24440149
25384214
7512027
9712030
9738502
|
IL10
|
ICAM1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
31.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
10925299
11207245
11438547
11875494
12193690
12811837
12818165
14607900
15282297
15579430
15749903
15833879
16200688
16424049
16713974
17404308
17485448
20184663
20435894
20547845
21115385
21191065
21220452
23124025
23508573
24378531
26755705
9834059
|
ICAM1
|
ITGAL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11786177
16595626
16354667
12526797
23602662
11279101
16189514
14507735
|
ICAM1
|
ITGB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
4062888
12208882
11279101
16189514
10352278
20187292
14507735
7642561
|
IL6
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
MYD88
|
CCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
MYD88
|
IL10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
IFNG
|
IL10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IL10
|
THBS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
10925299
11207245
11438547
11875494
12193690
12811837
12818165
14607900
15282297
15579430
15749903
15833879
16200688
16424049
16713974
17404308
17485448
20184663
20435894
20547845
21115385
21191065
21220452
23124025
23508573
24378531
26755705
9834059
|
VCAM1
|
ITGB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10438935
|
KLF1
|
HBB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
12556498
9418858
10575545
20676097
10468560
11287616
10535918
19220418
9668528
8195185
21610079
10706605
8916973
14764531
21539536
8924208
8918890
9207479
7753194
11259590
10652365
7829533
8901569
7682653
10990462
15833715
21220744
19251649
9545245
11238130
9603943
9707565
9778250
15384985
9422764
16705186
|
HGF
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11290563
12649206
15059978
16212809
17145802
18633355
19631971
20303741
22763439
23402812
23667593
26366398
26819959
27474009
28475121
9242465
|
HGF
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11290563
12649206
15059978
16212809
17145802
18633355
19631971
20303741
22763439
23402812
23667593
26366398
26819959
27474009
28475121
9242465
|
HGF
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
17145710
22897854
15167892
1655405
20624990
19433454
23331499
17804794
1846706
28475121
22001117
16537482
15218027
27147579
24362531
17667909
16397249
20178463
17981115
28534512
8380735
18495663
14685170
|
CD40LG
|
CD40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD40
|
â—¼ PROTEIN_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD40
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
1280226
1374165
19426221
7516405
11163401
7543281
12324477
10647992
17183360
|
MYD88
|
IL18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
MYD88
|
IL18
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IFNG
|
MYD88
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
MYD88
|
IL6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
TLR4
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22664090
19717524
20048342
21911421
9625770
17228323
17258210
11743586
15107846
15728506
12888566
21829704
18221795
10952994
17635639
17126326
12646618
|
TLR9
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
22664090
16410796
21911421
12791976
17417641
15107846
|
TLR2
|
MYD88
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
22673208
19717524
22664090
20348427
16893894
15107846
29990310
16798732
16482509
16293622
17126326
|
IFNG
|
TLR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11672593
11777960
11870632
11964313
12032143
12413632
12811837
12818165
14607900
15634932
15644117
15778339
15811952
15814715
16286920
16306937
16424049
16713974
16917499
17016554
17114424
17559085
1825141
18272812
19833085
20038811
20154735
20547845
20819927
21149606
21411734
23508573
24658051
26755705
2965306
6425450
9834059
9864217
|
IFNG
|
TLR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11672593
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16267105
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
THBS1
|
TGFB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10657674
11982756
14568985
14996710
21900405
22943793
8349738
|
THBS1
|
TGFB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22943793
8349738
21900405
1550960
|
EIF2B1
|
EIF2B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
12601012
12667446
16246152
23850759
|
EIF2B1
|
EIF2B2
|
â—¼ SHARES_COMPLEX
|
|
|
4.0
|
1.0
|
ACSN
|
12601012
12667446
16246152
23850759
|
THBS1
|
CD36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
10657674
11982756
14568985
14996710
17101731
20150200015
21378271
22943793
8349738
9295024
9763615
|
THBS1
|
CD36
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
10657674
11982756
14568985
14996710
17101731
20150200015
21378271
22943793
8349738
9295024
9763615
|
THBS1
|
SDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11257118
1969657
|
THBS1
|
CD36
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10487979
10772961
1379600
23640500
|
TLR2
|
CD36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
10549626
22028855
10426996
10364168
16880211
10490993
14977973
11123271
11431423
18178856
|
GATA1
|
HBB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
18586828
22164220
12556498
15358512
20564185
12556492
1559609
3243278
15833715
12379744
14695898
21220744
2461328
2911469
12193659
17196618
|