IL2RG
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
8643566
|
JAK1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
9670964
|
IL4
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12223527
23124025
|
STAT6
|
JAK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22254182
17433443
|
TYK2
|
STAT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15261459
23124025
|
IL13
|
STAT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15261459
23124025
|
IL4RA
|
IL13
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
11709756
11313257
22952195
7721786
33961781
|
IL4RA
|
TYK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
UTP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
PMYT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
ARHG8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
ANKL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
GOGA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
KCNT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
PKHH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
TR19L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
PRR11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
RHDF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
ZDHC9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IL4RA
|
RHBT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SHC1
|
IL2RG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
8643566
|
I13R1
|
TYK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10409622
16189514
|
JAK1
|
TYK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8702790
7589562
|
SHC1
|
IL4RA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11714803
10652211
|
TYK2
|
PTN6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
8780698
7629131
|
I13R1
|
IL4RA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8910586
18243101
|
IL4RA
|
STAT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11313257
9651359
8609418
8816495
15661890
9392697
|
PTN6
|
IL4RA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9392697
11714803
27742835
|
JAK1
|
IL4RA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
12242343
12133952
|
IL2RG
|
IL4RA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8266076
12242343
18243101
8266078
|
IL4RA
|
IL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7721786
9874253
11786020
10219247
18243101
8266078
23597562
|
I13R1
|
IL13
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11313257
11278629
8910586
33961781
18243101
20223216
|
IL13
|
STAT6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18852293
26208975
29771943
|
IL2RG
|
IL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
18243101
8266078
|
JAK1
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
70.0
|
1.0
|
ACSN
|
10358772
10426994
10485906
10807786
10820393
10849428
10856136
11160275
11371360
11867689
11870632
11907067
12095053
12223527
12244150
12401408
12496409
12811837
12818165
14607946
14610620
15289500
15536084
15563472
16081783
16212621
16243976
16413922
16713974
16785506
16799562
16815076
17371980
17398124
17404308
17459805
17485448
18250477
1825141
18758473
19528259
19833085
19913445
20007590
20184663
20406969
20510870
20856220
21307131
21469115
21840487
22224781
23124025
23390297
23650441
24030977
24091328
24751819
24829413
25582338
26755705
27216177
2965306
6164929
7512720
7521688
7523571
8683106
9625766
9834059
|
JAK1
|
IL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
JAK1
|
IL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21115385
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
JAK1
|
TYK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
85.0
|
1.0
|
ACSN
|
10433356
10485906
10542212
10623821
11160275
11207245
11306493
11371360
11698286
11867689
11870632
11875494
11964292
12223527
12401408
12496409
12754507
12811837
12818165
1439146
14607900
14610620
14657224
14764699
15099563
15282297
15356132
15573129
15579430
15864272
16200688
16243976
16413922
16424049
16713974
17404308
17485448
17513775
18209571
18250477
1825141
18451175
18555777
18555778
19581928
19833085
20138012
20184663
20406969
20510870
20856220
21097505
21115385
21191065
21220452
21469115
21840487
21930765
21930769
22595692
23034983
23124025
23390297
23567181
24011634
24030977
24091328
24346288
24418198
25002027
25582338
26201938
26268945
26755705
27216177
27557510
2965306
7512720
7521688
7543512
7590867
8837607
9535722
9834059
9845545
|
JAK1
|
TYK2
|
â—¼ SHARES_COMPLEX
|
|
|
85.0
|
1.0
|
ACSN
|
10433356
10485906
10542212
10623821
11160275
11207245
11306493
11371360
11698286
11867689
11870632
11875494
11964292
12223527
12401408
12496409
12754507
12811837
12818165
1439146
14607900
14610620
14657224
14764699
15099563
15282297
15356132
15573129
15579430
15864272
16200688
16243976
16413922
16424049
16713974
17404308
17485448
17513775
18209571
18250477
1825141
18451175
18555777
18555778
19581928
19833085
20138012
20184663
20406969
20510870
20856220
21097505
21115385
21191065
21220452
21469115
21840487
21930765
21930769
22595692
23034983
23124025
23390297
23567181
24011634
24030977
24091328
24346288
24418198
25002027
25582338
26201938
26268945
26755705
27216177
27557510
2965306
7512720
7521688
7543512
7590867
8837607
9535722
9834059
9845545
|
JAK1
|
IL2RG
|
â—¼ SHARES_COMPLEX
|
|
|
70.0
|
1.0
|
ACSN
|
10358772
10426994
10485906
10807786
10820393
10849428
10856136
11160275
11371360
11867689
11870632
11907067
12095053
12223527
12244150
12401408
12496409
12811837
12818165
14607946
14610620
15289500
15536084
15563472
16081783
16212621
16243976
16413922
16713974
16785506
16799562
16815076
17371980
17398124
17404308
17459805
17485448
18250477
1825141
18758473
19528259
19833085
19913445
20007590
20184663
20406969
20510870
20856220
21307131
21469115
21840487
22224781
23124025
23390297
23650441
24030977
24091328
24751819
24829413
25582338
26755705
27216177
2965306
6164929
7512720
7521688
7523571
8683106
9625766
9834059
|
JAK1
|
IL4
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21115385
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
JAK1
|
IL13
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
JAK1
|
STAT6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
JAK1
|
IL4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
34.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21115385
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
JAK1
|
IL2RG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
70.0
|
1.0
|
ACSN
|
10358772
10426994
10485906
10807786
10820393
10849428
10856136
11160275
11371360
11867689
11870632
11907067
12095053
12223527
12244150
12401408
12496409
12811837
12818165
14607946
14610620
15289500
15536084
15563472
16081783
16212621
16243976
16413922
16713974
16785506
16799562
16815076
17371980
17398124
17404308
17459805
17485448
18250477
1825141
18758473
19528259
19833085
19913445
20007590
20184663
20406969
20510870
20856220
21307131
21469115
21840487
22224781
23124025
23390297
23650441
24030977
24091328
24751819
24829413
25582338
26755705
27216177
2965306
6164929
7512720
7521688
7523571
8683106
9625766
9834059
|
IL2RG
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
7973658
7721895
8580378
|
JAK1
|
TYK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8702790
19901323
7504784
7589562
15659558
30029643
|
JAK1
|
STAT6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
9852261
23331499
9045682
22661199
22000020
10856136
23124025
|
TYK2
|
IL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20856220
21115385
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
TYK2
|
IL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
TYK2
|
IL4
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20856220
21115385
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
TYK2
|
IL13
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
TYK2
|
STAT6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
TYK2
|
IL13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
IL2RG
|
IL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL2RG
|
STAT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9651359
7796300
23124025
15805299
8085155
|
IL2RG
|
IL4
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL2RG
|
STAT6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
18243101
79183788266078
11418623
8266078
7918378
|
IL4
|
STAT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9651359
7796300
23124025
15805299
8085155
|
IL4
|
STAT6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4
|
IL13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
STAT6
|
IL4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
9317131
10369418
9647237
12605697
11687571
20980261
10528163
23913966
12244176
10373589
9786931
12138096
22226123
16647686
17878383
8816495
20620946
21081493
23727894
17041005
9295035
12778491
14993689
9199300
21949021
12218118
8760793
19419769
10820389
16914450
15695802
11150515
20225206
15922518
12082548
8624821
20214667
10364072
9110977
11544308
17433443
17645498
25037220
19604304
15728480
9845517
18400747
12776189
10982806
16084752
20828825
21751242
|
IL4
|
STAT6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24508458
18852293
22142941
29925830
17306571
25428220
|
IL13
|
STAT6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|