Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABCA1 CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 583591 25170080
CANX ABCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 583591 25170080
SOAT1 CANX â—¼   COLOCALIZATION 2.0 0.8 intact 8372609 22045338
HNF4A LDLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21123766
HNF4A SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12763030 22190905
HNF4A ABCG5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21123766
HNF4A PCSK9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21123766
HNF4A LIPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16603721
NR1H4 APOC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12454263 11579204
NR1H4 APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12891557 15047603
ABCG8 ABCG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16870176 5218866
VDAC2 LRP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VDAC3 VDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VDAC3 VDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APOC2 LPL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10727238 11579204
VDAC3 APOE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VDAC1 APOE â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
VDAC1 VDAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 22939629 29128334
APOA1 APOB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28183703 7592581 19164805
APOA1 APOA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10722751 24981860 3104518
LDLR MYLIP â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
APOA1 APOC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15174051 11991719
LRP2 APOE â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11421580 7768901 16713569
VAPA VDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26344197 26496610
LRP2 APOH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9727058 16713569
VAPA VDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 26344197 26496610
NPC1 NPC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20674861 27238017
VDAC2 VDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31536960 22939629 30021884
LRPAP1 SORT1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
APOA1 LCAT â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PLTP APOA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 9469594
LDLR APOB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24447298 12031600
APOA1 PLTP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11854286 9469594
LRP1 LRPAP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
LDLR APOE â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24447298 12036962 20030366
APOA1 ABCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12084722 30458687 27017521
VDAC1 VDAC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31536960 22939629 29128334 30021884
LRP1 APOE â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 2779654 11421580 20030366 15182176
VAPA VAPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19515777 16227268 9920726 26496610 33961781 26186194 34079125
PCSK9 LDLR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18250299 22081141 25613181 18753623 17435765 23085658
MYLIP LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30896554 26666640 23382078
HNF4A ABCG8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21123766 17403900
HNF4A APOC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9651383 9461615 19252740
HNF4A CYP27A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12957378 11867220
ABCG8 ABCG5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12208867 16870176 27144356
LCAT APOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 4335615 15654758 16189514 1644835 10026251 10222237 1587806 17676061 3104518
NPC1 NPC2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
LDLRAP1 LRP2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
ABCG5 ABCG8 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
LDLR PCSK9 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
LRPAP1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 10747918 1718973 1374383 14596620 20030366
HNF4A APOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8369280 1639815 9880489
HNF4A APOA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17556588 9366246 15928313 16338932 7984419 8257717 15583007
LRP2 LDLRAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 14528014 23836931 7768901 8710919 8706697
APOE LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12036960 24447298 31677479 20030366 12036962 15840700 11327878
PCSK9 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22081141 29209441 17435765 25613181 23085658 18753623 18250299
APOB LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12031600 24447298 11986215 15840700 1132787812031600 11327878
HNF4A APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7838720 9003181 7961760 8464705 22282358 8626539 9357782 7615825
HNF4A APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 1312668 11229886 12631740 22197810 8760876 9012660 16584384 9366246 20516075 11802721 11839757 16771709 2279702 12454280 7640286 7984419 1639815 9760243
HNF4A APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11244563 11229886 9921275 15933209 10859308 8344962 1639815
HNF4A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 23626788 23038264 17920062 10627496 17603092 21963511 15933209 9013589 16488887 16492670 9799805 15331348 17660447 16049268 11402042 17636037 15322103 16323215
HNF4A APOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8626539 8464705
NR1H4 ABCB11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18270374 15471871 16819395 17135343 12135489 16371446 23546875 22345554 11387316 18668687 19833092 12052824 11870371
APOA1 ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 30458687 12084722 12869555 22271762 27100352
APOA1 LCAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 1587806 10222237 10026251 19860440 16189514 15654758 4335615 17676061 1644835