CEBPG
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8175747
15109267
|
CEBPG
|
CETP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10487481
1429586
|
PPM1G
|
LRPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
POLA2
|
LRPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
NUMA1
|
LRPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RTN4
|
LRPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
LRPAP1
|
AGTPBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
LRPAP1
|
RAPGEFL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
LRPAP1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MTOR
|
EIF4EBP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12150926
15809305
|
APP
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RALGDS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0808110105
19075231
|
CD36
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
LRP1B
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SCARB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SORL1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
ROCK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
VLDLR
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19116273
0807594106
|
ABCG8
|
ABCG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16870176
5218866
|
VDAC2
|
LRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VDAC3
|
VDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VDAC3
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
APOC2
|
LPL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10727238
11579204
|
CD81
|
APOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32900848
30024968
|
CD81
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32900848
30024968
|
VDAC3
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VDAC1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
VDAC1
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31536960
22939629
29128334
|
APOA1
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28183703
7592581
19164805
|
APOA1
|
APOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10722751
24981860
3104518
|
LDLR
|
MYLIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
APOA1
|
APOC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15174051
11991719
|
LRP2
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11421580
7768901
16713569
|
VAPA
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26344197
26496610
|
LRP2
|
APOH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9727058
16713569
|
VAPA
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22939629
26344197
26496610
|
NPC1
|
NPC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20674861
27238017
|
VDAC2
|
VDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
22939629
30021884
|
APOE
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
LRPAP1
|
SORT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
VAPA
|
VAPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
APOA1
|
LCAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
SMAD2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CEBPB
|
CEBPG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12177065
20102225
|
PLTP
|
APOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
9469594
|
LDLR
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24447298
12031600
|
APOA1
|
PLTP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11854286
9469594
|
LRPAP1
|
SORL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
RELN
|
VLDLR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
LRP8
|
RELN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
LRP1
|
LRPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
APP
|
SORL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
LRP8
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12950167
8626535
12167620
32814053
|
LDLR
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24447298
12036962
20030366
|
LRP8
|
RELN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21844191
17548821
12670700
23951306
12899622
12167620
10571240
28446613
28123028
|
APOA1
|
ABCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12084722
30458687
27017521
|
VDAC1
|
VDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31536960
22939629
29128334
30021884
|
LRPAP1
|
VLDLR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CEBPG
|
LRPAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12477864
12915572
15722556
|
LRP1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
2779654
11421580
20030366
15182176
|
TP53
|
SUMO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
24782567
25218447
21900752
|
VAPA
|
VAPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
19515777
16227268
9920726
26496610
33961781
26186194
34079125
|
PCSK9
|
LDLR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18250299
22081141
25613181
18753623
17435765
23085658
|
MYLIP
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
30896554
26666640
23382078
|
RELN
|
VLDLR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21844191
10571241
12670700
12899622
14724251
10571240
28123028
|
ABCG8
|
ABCG5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12208867
16870176
27144356
|
LCAT
|
APOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
4335615
15654758
16189514
1644835
10026251
10222237
1587806
17676061
3104518
|
NPC1
|
NPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
LDLRAP1
|
LRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
ABCG5
|
ABCG8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
LDLR
|
PCSK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
EIF4EBP1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
CEBPG
|
APOB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8557677
1545795
2161847
2258060
|
LRPAP1
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
10747918
1718973
1374383
14596620
20030366
|
LRPAP1
|
VLDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
7592875
8083232
10571241
20223215
|
MTOR
|
EIF4EBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
132.0
|
1.0
|
Omnipath
|
17510057
17081983
11691836
22873724
18767875
16824195
19147279
23077579
24303063
28272965
19690332
11438723
12665511
17043358
19413330
10405182
20670887
19209957
19664995
15070431
9826548
12747827
10942774
16242075
9092573
12604610
20068231
9465032
21190521
23360111
17991864
25686248
9204908
11777913
18669648
12150926
8083223
20537536
12105188
17386266
24205284
17517883
26985829
19291795
23972597
16288292
17487921
8895571
17287340
9405468
20227039
12588975
12370290
17717968
23486913
19651622
10779345
26255626
18220336
16404421
18283322
10364159
15066126
12912989
17693255
15767663
|
CEBPB
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19135161
23564453
19075931
24333671
|
APOC1
|
VLDLR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22461740
17339654
26129832
8294473
12700345
|
LRP2
|
LDLRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
14528014
23836931
7768901
8710919
8706697
|
CEBPB
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10473624
11111087
19150388
10364248
10319323
18583320
15059951
|
CEBPB
|
LDLR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12235180
16563127
19804198
12947119
|
APOE
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9202294
10559559
10428074
10842709
17116874
|
APOE
|
LRP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8626535
12167620
12950167
16504486
|
APOE
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
12036960
24447298
31677479
20030366
12036962
15840700
11327878
|
APOE
|
SORL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11294867
11557679
|
APOE
|
VLDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
19116273
11278667
12167620
12870663
16504486
|
PCSK9
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
22081141
29209441
17435765
25613181
23085658
18753623
18250299
|
APOB
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12031600
24447298
11986215
15840700
1132787812031600
11327878
|
RELN
|
LRP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
12670700
12899622
10571240
23951306
12167620
28446613
16504486
|
RELN
|
VLDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10571240
10571241
14724251
11278667
16504486
|
APOA1
|
ABCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
30458687
12084722
12869555
22271762
27100352
|
APOA1
|
LCAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
1587806
10222237
10026251
19860440
16189514
15654758
4335615
17676061
1644835
|