Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
MIR149 PTGER2 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 21209948 22025564 25916550
MIR149 PTGER2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 21209948 22025564 25916550
MIR149 PTGER2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 21209948 22025564 25916550
PTGER2 IL6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21209948 22025564 25916550
MIR149 CDKN1A â—¼   DOWN_REGULATES ✅ - 9.0 1.0 ACSN 21145728 22902544 23377965 23453900 23550650 23665507 24206455 24272429 25916550
E2F1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9748148 9191053 16923815 17008321 10030670 10702805 15048076 17167174
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
CDKN1A E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
MIR149 E2F1 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 15944709 21145728 22902544 23377965 23453900 23550650 23665507 24206455 24272429 25916550
MIR149 AKT1 â—¼   DOWN_REGULATES ✅ - 9.0 1.0 ACSN 21145728 22902544 23377965 23453900 23550650 23665507 24206455 24272429 25916550