Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EHMT1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19010785
DOLK CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ATP6V1G1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPARGC1A CPT1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19233164 15199055
COX5A COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX5A COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LEF1 FHIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0703664105 18077326
IPPK CERS6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IPPK CERS5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DGUOK ATP4A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GSK3B MAP2K7 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
COX4I1 COX6A1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ATP6V1B1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
C1QB C1QA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14681455 21054788 12960167
FOXO1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22266855 12391153
FOXO1 GK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17317782 18805788 19740748
C1QA C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
C1QB C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6019133 12396008 10925294
GSK3B GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GOT2 GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22778263
ATP6AP1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1B2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
COQ6 COQ3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 27499296 26344197
ATP6V1B2 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ATP6V0C ATP6V1E1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
COX5A COX6A1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
C1QA C1QB â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
MCCC1 MCCC2 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
ATP6V1B1 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ATP6V1E1 ATP6V1G1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MAT2A MAT2B â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATP6V1B2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COX4I1 COX5A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
LEF1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17360796 10318916 17666529 19620402 19653274 12748295 15798764 17885813
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
GSK3B CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 26907733 16944320 27546592 11967263 14663202 8524413 16504004 29969496 19767775 21347341 25142862 11311237 30736789 14597415 25591548 19645770 10385618 20548028 10766840 10929713 23565238 16039586 17570479 18818515 18167338 12615961 12413951 17046823 19071090 18598945 15465828 19374252 26121043 26432751 18319725 12969793 23733133 22922870 24134204 10486203 12459251 15020233 18769147 10910956 11152665 21317297 20537194 22099186 18328826 11124803 17070615 19757160 22470469 23552696 16732330 27695879 29554905 16103118 15075324 14536078 9832503 28090171
LEF1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
FOXO1 PPARGC1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 10364186 15668399 16122419 19449109 25464856
FOXO1 PPARGC1A â—¼   PROTEIN_INTERACTION 5.0 1.0 ACSN 10364186 15668399 16122419 19449109 25464856
HLCS MCCC1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22123817 16134170 20153287 9630604
HLCS MCCC2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22123817 16134170 20153287 9630604
CD14 FADD â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21737330 15814722 19278658 12620240 20308068 12181749
GALNT14 FADD â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10894161 17767167 19090789 20531300 28258062
MAP2K7 FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11034606 10640736 16061179 15001534
PPARGC1A COX5A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
CREB1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20359506 17451429 17018277 21156859 11557984 22980225 15653680 19583954
COX5A COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX4I1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
CD14 IRAK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
CD14 CXCL2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CREB1 CYP11B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21249615 11196473 20097716
CREB1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11160720 20857405 8641461 17325033 12869629 19343785
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
LEF1 DCT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22427932 1999537 12753399 12032083