Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAVS TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16360132
SMO NDFIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
NEDD4L SLC11A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0904880106 19706893
SNCA WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCR2 NDFIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
SLC11A2 NDFIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0904880106 19706893
BDKRB1 NDFIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
NEDD4 NTRK1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25921289 19953087 16701206 27445338 21332718
PTEN WWP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 33470109 21532586 25547115
PTEN WWP2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21532586 22427670 30016585 30849479 27295432 24063548 27852060 31592114 28475870 15717329 33039560
NEDD4 EGFR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR NTRK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
PTEN WWP2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NEDD4 PTEN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19345329 33712741 31469661 29593330 21986318 31578285 25047839 27295432 18498243 24063548 28437168 24141722 18307411 25547115 30594392
TGFBR2 SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
TGFBR2 NEDD4L â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
NEDD4 PTEN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NDFIP2 NEDD4 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
NEDD4L UBE2L3 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
SMURF1 UBE2L3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
NEDD4 UBE2L3 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
UBE2L3 WWP2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
UBE2L3 WWP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ITCH UBE2L3 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PTEN EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
NEDD4 PTEN â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17218260 17218261 17996703 18562292 19652529 22679284
NDFIP2 NEDD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12050153 12796489 26363003 15252135
NDFIP1 NEDD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11042109 11748237 26363003 27173227
NEDD4 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17218261 23331499 21071413 18307411 17218260 18562292 18498243 19345329 19652529 30594392
SMURF1 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11278251 15221015 22298955 15761148 21572392 27048878 22949611
ITCH MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19881509 27736772