Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
NFYC NFYB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215853 12401788
IKKA P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 11805286 16713569 17434128
MYC TDG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 26496610
SKP2 P73 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NFYC P73 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15454570 12167641
LMBL1 P73 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CF141 P73 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NFYB EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10075648 9799238 15454570
EP300 P63 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30986748 25911675 23589370 15965232
IER2 P73 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TDG P73 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10961991 18951877
TDG P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10961991 18951877
P73 NFYB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15454570 12167641
P53 NFYB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23734815 15831478 16959611
P63 DAXX â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15339933 12954772
P73 KAT2B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14614455 18663001
MDM4 P73 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 29523541 21088494 30603043 33961781 11223036
DAXX P73 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15339933 12954772
P53 ABL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10713716 16713569 10629029
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
IKKA MYC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33461590 21575199
P53 ITCH â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21474069 32807901 16908849 18559494
P73 P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9802988 25417702 21508668 9891077 11238924
MYC SKP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SKP2 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22770219 18243116 26593157
P63 YAP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27780825 11278685
WWOX P73 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15070730 24550385
IKKA P73 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17452332 21482671
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
NFYC MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
P73 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12080043 11844794
MYC SKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23277542 12769844 12963825 26038816 17157259 24259667
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
P63 P73 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 11238924 19815500 17446929 33961781 22252508 10373484
ABL1 P73 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11278685 10391250 10391251 25893286 19442657
ABL1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16702947 25624478 12110584
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9809062 15295102 21471221 26229107 15337767 23010591 18485870 15558054 22266186 15509808 26625199 9194564 23402884 23870121 17438265 16959611 12690203 17906639 24821727 15664194 21187340 33196849 17977830 11804596 25288747 15186775 18612383 23796514 19234109 27818144 19339993 24157709 9652736 28757384 12499368 17452980 9891054 23880760 31167125 15542844 22013068 16713569 9288740 17189186 11782467 16543236 23329847 10942770 26302407 23307557 22074660 19218448 19217391 10601022 16024799 16782091 12501250 11433299 22731250 23728348 10518217 9194565 25651062 12724314 14612423 16611888 19805293 18243116 32807901 29706626 20234175 16678111 14759370 25867071 25156994 11907332 16438982 16135789 11070080 11359905 25753752 16537920 9744860 18391200 15965232 10490106 16928824 12162806
EP300 P73 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10648616 11804596 15175157 19218448 18663001 15893728 15454570 25675294
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
MYC KAT2B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572685 35140242 12660246
KAT2B P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19680552 17977830 16678111 15965232 20589832 10891493 12068014 17189186 9891054 10490106 16537920 9744860 12501250 14614455 16959611
KAT2B MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21209460 21060154 32404984 14769800 12068014 28286521
MDM4 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 32300648 25512388 21988832 25384516 25809483 17616658 25105592 12874296 31796886 29295817 32075226 20705607 17301054 22493164 25703327 27777309 29523541 27617579 23028042 20473904 22120712 22333590 22902369 22745160 12860999 19432880 21925390 28205554 25659040 19838211 33985974 16055726 25961923 32427989 18566590 22266850 18219319 29057323 10608892 30598450 29524278 25825738 17159902 24813712 31024344 27621617 15604276 29262653 19619542 10218570 28628118 16227609 10827196 12393902 24755078 20724842 34551723 27215386 11606419 20484049 12370303 23671280 26001071 26720344 33961781 12483531 23946421 19683495 26359458
P73 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20588255 10435614 25417702 21261729 19218448 21088494 10321734 26025930 10469568 30603043 25301064 18499675 11223036 10207051
MDM4 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 29023092 30672125 31152661 17110929 19521340 10075736 30832340 22807444 12874296 25609649 11528400 24445145 17080083 18677113 20705607 27249653 9226370 17301054 18485870 26148237 27114532 16024788 22374672 24127580 18316739 26876197 29523541 21088494 23028042 24667498 30045945 20515689 25464845 22745160 19432880 21925390 28205554 20174603 21965653 25961923 21075307 22266850 8895579 28487147 32511789 10608892 30598450 25825738 19305137 19255450 11223036 15604276 16713569 28628118 16227609 10827196 12393902 20724842 24659749 12370303 23671280 17875722 33961781 31462704 26186194 23946421 31066983 19075013 15916963 19153082
YAP1 P73 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18640976 31496812 11278685 15893728 27292796 18280240 19111660 25283809 17110958
P73 ITCH â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30603043 17592138 15678106 17110958 32513985
ITCH P63 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20855944 33619536 16908849 22935697 25485500 23370280
WWOX P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12514174 31315632 16713569 14965474 16219768 15580310 11058590
P63 P53 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 16713569 25417702 19345189 11238924 23687300 21741598 24554706 22575646
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 15604276 5217417
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
DAXX MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23405218 18566590 18583933 16845383 15364927 20195357 28875283 23038753 21134643
P53 MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19303885 25417702 34408321 17268548 23252402 23880345 22807444 15094782 20962272 12529318 21726810 22124327 18981217 16173922 23318437 15558054 22524527 30584071 31626714 22301280 32516735 20174603 22912717 21075307 15848166 18566590 23483203 26882543 23402884 14671306 15001357 10889512 17908790 19411846 10640350 21561866 14499615 33503543 21986495 24998844 15908921 26673821 17098746 25362358 32066565 25739118 29295817 34362424 16595680 20591429 27336364 22745160 24462112 32427887 18467333 26578655 23261415 9271120 16055726 19357310 31591476 23169665 16338390 10608892 30464405 15542844 12612087 22266868 15550400 22331460 22914926 19071110 7686617 14559824 20959462 19941302 14596917 25512388 27129163 19597489 25609649 32904724 11351297 29121928 22487680 11709713 24127580 10562557 15358376 21584881 25312347 27826076 19098711 24980433 24413661 21887275 17116689 14612427 30948704 26001071 19857530 33061576 31138778 23802716 20234175 25313037 21988832 17616658 11744695 17666403 22525275 12897156 25156994 33020477 11925449 16152627 29876924 30244831 1614537 17363365 22474335 11112690 23443559 17297477 27905468 19085961 20479273 31940492 21261729 14517261 26908445 16866370 27893708 22653443 17470788 10488081 23370271 19223463 16751805 26556313 10734067 19411066 11223036 27856536 14704432 20124408 24240685 24842904 32901886 22948151 19234109 35140242 21084285 32894144 17848574 22737255 10561590 25168242 10435614 11697899 25543083 21572037 22920093 18604177 32874188 22659184 17591690 16845383 22444248 31239268 25283148 26186194 24200963 23826318 7689721 20047188 24314634 12167711 15308643 17318220 21857681 11431470 18815136 15950904 20705607 17525743 26876197 31177307 9529249 22374672 12915590 33650658 10601022 20837658 18223694 30097011 28205554 32334023 15247280 23776465 21268072 27308622 11713288 18234963 9582019 18784078 29487367 23776060 11713287 20484049 26720344 9131587 30109812 33961781 24361594 32807901 31066983 15824742 11562347 21454483 22157679 21088494 11070080 22575647 22083959 26540344 15210108 18332869 32528731 18172499 11094089 21132010 16414131 10827196 27031960 10892746 15280377 16023600 18665269 10202144 15058298 29549180 16212962 16905769 11278372 20657550 9809062 15295102 26238070 22391559 18061646 17310983 18485870 9278461 21925390 20659896 9824166 23150668 25637791 30598450 19160491 28605833 12690203 22467867 31594538 11572869 11384992 11486026 27807478 17936559 30679555 16678796 30252118 31652301 15144954 22411991 22084066 30175854 21478269 27543608 16624812 17290220 32097779 17301054 20694676 11714701 24667498 20395212 16547496 12381304 8058315 22266850 29755129 22085928 17159902 10196247 21316347 27886165 27215386 25384516 7926727 16964247 19081178 32198344 11046142 28549433 26350565 31533005 12867035 10321734 19590512 22991965 25277184 24207125 18541670 19166840 25103245 30320919 26883110 20235143 17139261 11597128 21071676 19568783 18813780 19805293 17056014 17989425 21317885 17234751 20588255 21170087 10347217 11839577 25954860 21060154 24926618 21750659 16331255 29269425 27811966 19305137 24659749 9450543 23201157 30879903 16870621 28362432 21149449 20570896 23609977 33765973 27106262 33355139 34040386 22588298 22389628 19033382 18264029 27462439 31092600 12208736 17369817 28082682 16579792 23246961 20708156 15013777 21465263 28542145 23572512 19483087 31665549 22975381 17438265 15604276 11178989 24488098 16432196 22227409 28628118 30005830 20639885 20847049 9363941 31406141 19816404 26475964 29899406 16861890 30320499 20660730 19332559 14702041 11284721 18316739 19837670 25464845 12426395 10681559 17302414 16107876 22510990 15154850 21098709 19106616 10722742 19188367 22366412 29524278 21084564 23134341 25624478 30455251 20173098 12620407 9223638 16713569 17426254 31647545 10766163 30454706 21471462 24621507 23652204 19153082 8875929 31152661 18309296 31968249 31796886 15122315 30532073 10980696 17080083 15064742 11285227 29547122 21965653 33495326 23728348 15242646 17347673 12842086 12944468 19255450 23671280 22916255 17875722 30355102 14741215 23946421 20591651 15053879 28514442 25241761 24567357 16215989 19656744 30832340 22262183 27249653 26203195 16857591 15313915 15933712 28223335 20542919 12552135 24643130 27282385 20080206 28553961 22819825 33579943 16159876 9724739 17380154 22318540 29997244 29670376 22103682 22032989 28394340 31903119
NFYC NFYB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 21988832 26496610 35140242 33961781 20936779 9388234 12401788 26344197
DAXX P53 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 25241761 16713569 14557665 12954772 15364927 16845383 32545337 21482821 23038753 27626385 28875283 12482984 15339933 21134643
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 YAP1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10837221 11804596 11971963 12628935 12709442 15459660 18835194 19788416 21051857 21199784 21435002 9168117
ABL1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20651945 29262653 26148237 19075013 20841568 28690977 29348869
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 25361080 19788416 21199784 29449692 18955976 21051857 18280240 21435002 18701449 27807512 20841568 21214929 21945154 29179447 15459660
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11864601
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
MYC SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24259667 12963825 12769844 23792459 21245140 24177224 23277542
SKP2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17145710 24259667 12963825 12769844 17157259 23277542 20852628 16376880 35260179 26038816
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
ITCH YAP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157