TP53
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8200620
21821029
|
MPDZ
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22653443
8415349
|
TP53
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TP53
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15230856
8732672
|
UBE2V1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1551980
11057907
|
TRAF6
|
NR2C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14633987
|
UBQLN4
|
TRIM32
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
UBE2V1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213148
11057907
|
UBQLN4
|
PELI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
THAP7
|
MDFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
IRAK4
|
PELI1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0900774106
19264966
|
IRAK1
|
PELI1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0900774106
19264966
|
HYAL2
|
PELI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
PELI1
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12804775
16951688
29720226
12496252
|
PELI1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
IRAK4
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23381138
16189514
11960013
|
FN1
|
TGM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
PELI2
|
SP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
PELI2
|
TRIM32
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
NUP62
|
PELI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
IRAK4
|
IRAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20485341
21903422
|
IRAK2
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12138165
21903422
10383454
|
TP53
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
PELI2
|
TMEM79
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
IRAK2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
TRAF6
|
UBE2V1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
PELI3
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18326498
25027698
12874243
15917247
23042151
|
IRAK2
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33799071
21988832
9374458
33961781
26250868
10383454
17878161
21903422
|
PELI2
|
IRAK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12860405
17675297
|
IRAK1
|
IRAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
TRAF6
|
UBE2N
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18710948
17327397
15147900
17709375
21113135
27791197
19810754
24610907
29950522
27695001
27918549
31074699
34490261
18617513
30979779
25548215
11057907
19465916
29537486
31638574
15327770
19549727
31578830
27173435
28244869
29432170
23885119
|
PELI1
|
IRAK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
17675297
12496252
19264966
21204785
16951688
17997719
|
IRAK4
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24735611
12860405
19166926
18221795
12538665
17785851
11960013
16024789
16951688
17276401
21903422
|
PELI3
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16884718
17675297
18326498
25027698
12874243
15917247
19081057
|
PELI1
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16884718
26082489
17675297
12496252
19264966
21204785
15917247
16951688
17997719
19081057
|
IRAK4
|
PELI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
MDFI
|
PELI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
IRAK1
|
PELI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
IRAK1
|
PELI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
TRAF6
|
IRAK1
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18347055
|
UBE2N
|
UBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
31638574
14517261
18678647
25527291
27173435
30097011
33619271
27182664
29537486
|
IRAK1
|
PELI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
UBE2N
|
UBE2V1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
IRAK2
|
IRAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
IRAK1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
TRAF6
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
22033459
24735611
11397809
19716405
17197697
30872404
8837778
10346818
17785851
11960013
18234474
16951688
16024789
11287640
12034707
21220427
23381138
19166926
24434549
28882891
18056395
11259596
23244239
12496252
22447928
20043910
12566447
11518704
12242293
10920205
10383454
18347055
9374458
31921110
14625308
|
PELI2
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16884718
12370331
17675297
12860405
25027698
15917247
19081057
|
TRAF6
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
HNRNPK
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18472002
16360036
23092970
|
TP53
|
TP63
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
10606233
16931914
18388131
16516862
14576823
11382762
20442293
23019126
19858204
11238924
11423969
|
TP53
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11238924
18431400
16713569
|
TRAF6
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
TRAF6
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
TRAF6
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
12738796
14660645
15125833
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
|
UBE2N
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
18710948
1551980
17327397
11057907
15147900
18981220
21113135
17709375
31074699
19549727
18617513
24610907
27791197
29432170
19465916
23885119
15327770
27173435
21872579
25548215
|
IRAK4
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12496252
16189514
11960013
|
IRAK1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
10346818
17145710
17785851
16024789
14625308
11259596
10383454
18234474
9374458
11287640
23244239
21220427
11518704
19166926
16951367
15894263
10747026
35926385
18056395
12566447
12496252
22447928
12242293
8837778
10920205
11960013
19716405
24735611
20043910
24434549
17785432
11397809
18347055
22033459
12140561
23381138
17197697
|
IRAK2
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
21988832
10383454
21903422
9374458
12659850
17878161
26250868
24973222
33799071
|
UBE2N
|
UBE2V1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
15492226
29662619
10089880
1551980
11057907
16129784
25260751
15147900
22367539
18082144
18678647
26101372
20551964
16307917
17709375
19549727
18029035
21460221
24145445
16215985
20613989
25548215
|
PELI3
|
PELI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
17675297
12496252
12860405
15917247
17997719
|
PELI1
|
PELI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
17675297
12496252
12860405
15917247
17997719
|
IRAK4
|
PELI2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17675297
17145710
12860405
|
PELI2
|
IRAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
18326498
12370331
17675297
17997719
12860405
16884718
19081057
|
IRAK4
|
IRAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IRAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
IRAK4
|
IRAK1
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IRAK2
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
IRAK4
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
12738796
14504095
14660645
14662834
15099563
15125833
15802534
16252010
16878026
17704786
17948050
18264787
18758450
18855897
18922473
18977329
19161412
21614932
23070005
23681101
23811849
26885855
27048821
27066895
9469432
|
IRAK4
|
IRAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
17145710
17785851
18252867
17276401
16024789
14625308
15084582
21903422
15292196
25452754
19775907
18221795
15905496
19166926
12538665
12860405
14751757
12496252
11960013
24735611
26143580
17337443
|
IRAK2
|
IRAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
IRAK1
|
IRAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
10383454
21903422
16024789
12138165
24973222
|
PELI3
|
IRAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17145710
18326498
17997719
17675297
12874243
16884718
19081057
|
IRAK1
|
PELI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
17997719
17675297
16884718
16951688
19081057
26082489
12496252
19264966
|
IRAK1
|
PELI3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17145710
18326498
17997719
17675297
12874243
16884718
19081057
|
PELI3
|
PELI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
17675297
12496252
12860405
15917247
17997719
|