Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
FGF2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9490736 12750158
ABHD5 PNPLA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17189257 23297223
PPARG BCO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24071514 16504037
PPARG CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
PPARG PNPLA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17848638 18189154
PPARG GSTA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15150131
IRS1 LEP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15316008 17565041
PIK3CD IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
LEP IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15316008 17565041
TFE3 IRS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23885019 17279346
GAPDH PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ENPP1 INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10615944
AGPAT3 CREB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TFE3 ACP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21209915 11818452
PPARD LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10634806
AMACR FKBP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LPIN3 LPIN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ABHD5 PNPLA2 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ACO2 CKB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
NDUFA12 NDUFB1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
EGFR GAPDH â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
NDUFB1 NDUFB9 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
AKR1C2 AKR1C3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ACO2 GOT2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
INSR IRS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8662806 8626379 9195949
ENPP1 INSR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11289049 10615944
MAPK1 ALOX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12670876 12205041
GSTM3 GSTM5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 25416956 33961781 26186194
PPARD PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20097210 10991946 20176998
IRS2 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9113989
GOT2 GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CGA CHST8 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11445554 18431515 10988300
IRS1 PIK3R3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
INSR IRS1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 7651388
INSR IRS1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
GSTM3 GSTM5 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
NDUFB1 NDUFB5 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
NDUFA12 NDUFB5 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NDUFB5 NDUFB9 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
INSR IRS1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11781100 25667086 16582879 17167487 7935368 10455177 11606564 7499194 15629149 8662806 8626379
NDUFB7 NDUFB9 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NDUFA12 NDUFB9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPARG EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15486348 18332871 18288266 23370527
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
EGFR PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17496910 31980649 25241761 16273093 24658140 25402006
EGFR GSTP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19254954 26429914
MAPK1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 25409419 11733495 16574647 9099735 9030579 15507114 26670611 17570479 17998334 18596912
MAPK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 15001544 17081983 18949383 16123357 27014871 16914728 17360977 16099428 30401435 16131083 17640984 12510059 15613682 21850561 14579029 20594869 8626671 9395471 19651622 15576463 22289259 14769130 16020478 17242212
NDUFB1 NDUFA12 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA12 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB5 NDUFA12 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA12 NDUFB7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB5 NDUFA12 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFA12 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFA12 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA12 NDUFB7 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFAF2 NDUFA12 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15526035 16200211 16218961 17344420 20025615 20816094
NDUFB5 NDUFB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFB7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB5 NDUFB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB1 NDUFB7 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFAF2 NDUFB1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15526035 16200211 16218961 17344420 20025615 20816094
NDUFB9 NDUFB5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB5 NDUFB7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB5 NDUFB7 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFAF2 NDUFB5 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15526035 16200211 16218961 17344420 20025615 20816094
NDUFB9 NDUFB7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB7 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFAF2 NDUFB7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15526035 16200211 16218961 17344420 20025615 20816094
NDUFAF2 NDUFB9 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15526035 16200211 16218961 17344420 20025615 20816094
PPARG TNFRSF11B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11485016 20150512 12056809
PPARG LEP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9030601 20473515 15764598 19954946 23254958 19689798
PPARG LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17658475 10098492 8895578 18948972
INSR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 10655627 7651388 25472611 1385403 18083107 12220227 23331499 28328746 7504175 19534553 7499194 7537849 7935368 11572799 11781100 10592173 17570479 17575262 18988627 12446583 15629149 10455177 15870194 11416002 12101187 17167487 8530377 8626379 8662806 11606564 2159922 8626723 16020478 16582879
IRS1 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16931767 12175651
IRS1 PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 9415396 16931767 12175651 10417350 7542745 25814554
INSR IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 19901323 7629118 9195949 18083107 23331499 19534553 7537849 17570479 18988627 7675087 11584304 7526222 12101187 8626379 8662806 8626723