H2AX
|
PPP2CA
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8209912
18758438
|
NOTCH1
|
DLL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
20351093
22363487
|
NOTCH1
|
DLL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
20351093
22363487
|
NOTCH1
|
LFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15207708
22298955
|
POFUT1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12697902
12909620
|
NOTCH1
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22330899
22363130
|
B4GALT1
|
NOTCH1
|
â—¼ GLYCOSYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11707585
10935626
|
NOTCH1
|
POGLUT1
|
â—¼ GLYCOSYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18243100
21490058
|
ESR1
|
B4GALT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14605097
|
POFUT1
|
MFNG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15380241
|
POFUT1
|
LFNG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15380241
|
POFUT1
|
GALM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15380241
|
ESR1
|
PLOD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25604459
31527615
|
DVL1
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12650946
|
ESR1
|
NOTCH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19376833
|
ESR1
|
POFUT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
MFNG
|
DLL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12036964
|
JAG1
|
NOTCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
DVL1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
15888125
12650946
15955531
|
PPP2CA
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20704570
23331499
19951945
|
SMAD3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11555647
23331499
|
SMAD3
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
16713569
14638857
18988627
|
NOTCH1
|
JAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NOTCH1
|
JAG1
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NOTCH1
|
JAG1
|
â—¼ LOCALISATION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
DLL1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17537801
11006133
9819428
21685328
1006133
16140393
98194281
22353464
|
LFNG
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10935626
16713569
12486116
|
MFNG
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16713569
10935626
12486116
|
JAG1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18495817
16921404
15137944
769772111006133
16713569
23331499
21071413
23086448
22363130
18988627
21820430
18292500
18660822
22330899
17537801
11006133
7697721
10958687
22353464
|
NOTCH1
|
LFNG
|
â—¼ GLYCOSYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10734111
16385447
9187150
10935637
9207795
|
NOTCH1
|
POFUT1
|
â—¼ GLYCOSYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
18347015
11524432
21464368
12486116
15692013
|
MFNG
|
JAG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12036964
23331499
15574878
|
JAG1
|
NOTCH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
23331499
18660822
22330899
21071413
16921404
18988627
10958687
22363130
10551863
22353464
|
JAG1
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22330899
16921404
11006133
14714274
22363130
18660822
12482954
22353464
|
JAG1
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
29910816
22330899
22363130
24563863
22353464
|
DVL1
|
LRRK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
20006983
19625296
|
PPP2CA
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15367694
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
ESR1
|
CAV2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12711000
12138116
18414489
|
AKT2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11139588
11432835
11507039
9528769
7838153
|
LFNG
|
NOTCH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11346656
|
MFNG
|
NOTCH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11346656
|
DLL1
|
NOTCH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
21685328
10958687
22353464
23111325
9244302
|
NOTCH2
|
POFUT1
|
â—¼ GLYCOSYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
18347015
11524432
21464368
12486116
15692013
|
DLL1
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
21685328
11006133
12482954
22353464
|
POFUT1
|
NOTCH3
|
â—¼ GLYCOSYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
18347015
11524432
21464368
12486116
15692013
|
DLL1
|
NOTCH4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
29910816
22353464
|
NOTCH4
|
POFUT1
|
â—¼ GLYCOSYLATION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
18347015
11524432
21464368
12486116
15692013
|