Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PPP2CB PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PPP2CA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PPP2R1A PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PTPN11 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
PTPN11 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
ACTB PPFIA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPFIBP1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PPP2R5A PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
PPP2R1A PPFIA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R1A PPFIA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R5A PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8287037 7592815
PPP2CA PPFIA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
MBIP PPFIA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PPP2R5D PPFIA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PPFIA1 TNNT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PPFIA1 AGTPBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PPFIA1 DNAJC5 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PPFIBP2 DTNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YWHAZ CDK18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ PPFIBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
PPP2CB PPP2R5A â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
PPFIA3 PTPRD â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
PPP2CA PPFIA1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 27880917
DTNB TXLNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956
LRRK2 YWHAG â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
ESR1 NCOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 0.83 0.83 Signor 11477071
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ESR1 CCNH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12527756 31527615
PPFIA1 PPP2R5D â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
BRCA1 TUBG1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 NCOA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14578343 11085509 16860316
PTPRD PTPRS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9566880 22357843 28675297
LRRK2 YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPFIA1 PTPRF â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ERC2 RIMS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14734538 12163476
PPFIA3 PTPRF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
PPP2R1A PPP2CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936019 16039140
MAPK6 PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RIMS1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12871946
PTPRD PPFIA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
PTPRF PPFIA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
PTPRD PPFIBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
PTPRD PPFIBP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
PTPRF PPFIBP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
PTPRF PPFIBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
PTPRS PPFIBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
PTPRS PPFIBP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7796809 15750591 9624153
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PPP2R1A PPP2CB â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217765 15936019
PPFIA2 PPP2CA â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
NCOA2 ESR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14766010 12612084 11250900 12837248 17697320 11376110 9430642 11265755 20348541 19460354 18499756 12630920 12714702 9192892 15657427 11014206 16645043 11937504 12554772 26487511 9774463
ESR1 NCOA2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
PPFIA1 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPFIA2 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPFIA1 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPFIA3 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CB PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
RHOC ACTB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21576392 15507212 22275430 16439214 23222643 24914801 22094460
KRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
NRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA PPP2R5A â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ESR1 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18499756 9192892 9430642 11014206 19460354 15657427 23331499 11477071 26487511 16645043 12612084 20348541 12630920 14766010 17697320 11937504 12714702 12554772 9774463
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
UNC13B PPFIA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
TSPOAP1 PPFIA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
PPFIA1 RIMS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
PPFIA1 PTPRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9624153 16713569 8524829 7796809
PPFIA3 RIMS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
PPFIA3 TSPOAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
UNC13B PPFIA3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
UNC13B PPFIA2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
PPFIA2 TSPOAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
PPFIA2 RIMS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
KRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
UNC13B RIMS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
TSPOAP1 RIMS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
RIMS1 UNC13B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11797009 31679900 11343654 12163476
UNC13B TSPOAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12871946 17891149 17478680 11278839 12519779
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501