Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PSEN1 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CDC37 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRAM1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 DYNC1H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9781666 9627114
FXR2 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
A2M LYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
SUMO1 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PSEN1 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
SUMO1 SP100 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
KLK6 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
TP53 DLST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17916908 21191025
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
PRAM1 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRAM1 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 PRAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRAM1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RNF32 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RNF32 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRAM1 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEK7 PRAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRAM1 MAST1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRAM1 KLK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRAM1 A2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
H1-4 PRAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RNF32 PRAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
PRAM1 CDK5R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H1-4 RNF32 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP100 SUMO1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
APP CALR â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
SKAP1 SKAP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NEK6 NEK7 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RARA SUMO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15171703 24819975
SUMO1 MBD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17066076 24654937
APP KLK6 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
APOE APP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PML RARA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PML HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11259576
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RARA PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11050004 1311253 16189514 16713569 16540467 10882117 17560333 18073335 10610177 12935927 20159610
SUMO1 SP100 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11313457 16189514 25416956 32296183 16524884 21880768 24654937 15017387 24637324 10212234 17491593 9412458
NEK6 NEK7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17353931 32814053 33961781 26186194 32707033
FXR2 LCP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BCAR1 LYN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9581808 9020138
SUMO1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11948183 16189514 9885291 19015637 21305000 23028697 28851805 23604351 15017387 22155184 21057547 19380586 24190887 20826694 20972456 23830076 17027752 24654937 25497731 9756909 21779164 31879127 17081986 18625722 8806687 17081985 17344210 19217413 17036045 18474224 9452416 20188669 16501610 22406621 22875967 9427741 15561718 21098080 11080164 11160742
NCOR1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11430826 10882117 16713569
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
NCOR1 RARA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9531570 19377461 10336495 16606617 25303530 21988832 27107012 9121466 10882117 15604093 16469706 30532072 18978041 15336696 7566114 9486655 20543827
SKAP2 LYN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 29568343 9837776
HDAC3 NCOR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16917504 11466315 10944117 21258344 11509652 16195251 16469706 14722073 15601853 12628926 11931768 11804585 14527417 16980585 23752268 29523594 16713569 10860984 11013263
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOR1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
LYN BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9581808 9020138 10428862
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
PSEN1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10635315 11226248 16126725 11953314
TP53 CDK5R1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10604467 17591690 12064478 18490454 10500146
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
HDAC3 NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11509652 11013263 16195251 11931768 16469706 21258344 17694085 10860984 16917504 10944117 23752268 16713569 14527417 11466315 11804585 12628926 15601853
APOE APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202294 10559559 10428074 10842709 17116874