Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
CANX RNF113A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VCP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
AURKA HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17604723
PRDX4 PDIA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
TBXA2R PRDX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17644091 5220101
PRDX4 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRDX4 PDIA6 â—¼   COLOCALIZATION 2.0 0.8 intact 8090267 21057456
P4HB PRDX4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
PRDX4 PDIA6 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
KDM2B PRDX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18838535
RYBP SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR4A1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ESR2 TBXA2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17660955 16199482
GRN RYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
EP300 PRDX4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
AGR2 PDIA6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30575818 31436131
AGR2 PRDX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30575818 31436131
AGR2 PRDX4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30575818 31436131
AGR2 PDIA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30575818 31436131
ESR1 CLIC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
BMI1 PRDX4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 AURKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21761334 31527615
GRP78 PDIA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33957083
CFTR PDIA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
PRDX1 PRDX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
ATX1 PRDX4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32814053 25959826
PRDX4 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33957083 32457219
ESR1 PRDX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
RYBP FADD â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11395500 16189514
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
PRDX1 PRDX2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 22939629 26344197
ESR1 PDIA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
ERP44 PRDX4 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ENSG00000259040 PRDX4 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
GRP78 APOB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12397072 19164805
CFTR CLIC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
CFTR PRDX1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
CFTR GRP78 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22038833 29924966 26618866 17110338
CFTR PRDX2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
PRDX4 PRDX1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 33961781 9388242 21988832
CUL3 PDIA6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26949739
PRDX2 PRDX3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27173435 26344197
NCF1 PRKCZ â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TERF2 H2AX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21824286 21044950 22157895
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PDIA6 PRDX4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PRDX4 TXNDC5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CFTR GRN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26618866 31324722 29924966 17110338
PRDX1 PRDX2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EP300 NR4A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21988832 12082103 16713569 20438716
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
RYBP KDM2B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 23395003 27705803 22325352 33961781 24981860 26186194
CANX VCP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FADD TNFSF10 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
DUSP23 PRDX4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NCF1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
INS P4HB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25091901 31184304 21308844
NR4A1 PRDX4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP4K2 PRDX4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRDX4 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
GRP78 PDIA6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22939629 30021884 33957083 24189400
TNFSF10 FADD â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 10894160 5212774
KDM2B RYBP â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CANX RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PRDX4 RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
COL1A1 P4HB â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733
EP300 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 20438716 12082103 16713569
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
AURKA FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21978935 26563258
PRKCZ FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 11739185
PRKCZ NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626435 12734380 96198102 11145703 12056906 94375440 8089108
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21486948 23892277
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21233487