ESR1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16144913
|
NR1I2
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
|
ESR1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16144913
|
RXRA
|
NCOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17673910
5223765
|
NCOA1
|
ESR1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
5222291
17627277
|
NR1I3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15268900
21389059
|
NR5A2
|
HNF4A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12069850
10799577
|
PPARA
|
NR1I3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20208394
17962186
|
NR1I2
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
16189514
23160820
9489701
15604093
9727070
26855179
22976785
|
NR1I3
|
PRGC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26407237
15572376
|
HNF4A
|
NCOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
NCOA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
17627277
5222291
|
ESR1
|
NCOA1
|
â—¼ PROXIMITY
|
✅
|
|
0.84
|
0.84
|
mint
|
17627277
5222291
|
ESR1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9717844
23403292
9121466
|
HNF4A
|
NR1I2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15331348
16455805
|
PRGC1
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10558993
|
NR1I2
|
PRGC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15331348
16455805
15604093
15322103
|
ESR1
|
ERR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9395481
23403292
9058380
12522104
|
ERR1
|
ERR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
32296183
17488637
15604093
18673300
33961781
17157980
|
NR1I3
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
ERR3
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11864604
15604093
|
NR5A2
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
23975195
22504882
15604093
|
NR1I3
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
15572376
15604093
33961781
26186194
|
PRGC1
|
NR5A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20133449
22504882
17283069
|
NR1I3
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8114692
12130689
15888456
19682433
|
ERR1
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15337744
23975195
11165056
15604093
|
PRGC1
|
PPARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10669761
21775429
|
PRGC1
|
NRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10412986
11943463
|
PPARA
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PRGC1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10748020
18441008
12522104
|
PRGC1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12522104
11714715
|
PRGC1
|
ERR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
19914244
18063693
12470660
15821111
12181319
19171140
|
PRGC1
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23178929
17704298
14636573
18469005
19596656
12522104
18674809
12502716
19631645
16373399
30595551
17011503
17468099
22070604
15026545
17785586
10558993
19846556
30651555
17513608
|
PPARG
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23178929
17704298
10944516
15604093
19596656
17312272
10731636
16373399
30595551
17011503
17468099
22070604
15026545
10339548
10347167
9121466
9041124
23975195
20717101
10848596
9744270
17449869
11500849
16713569
11027271
11877444
15888456
17513608
30813326
|
PPARG
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22363753
16189514
12763030
10944516
31547433
30404011
20211142
35140242
25609649
17312272
23703729
7838715
19047629
12966085
22205725
14587029
10882139
30595551
30699358
9065481
21833030
9568716
34081964
21478865
9121466
23275339
17579352
19147680
26260846
16713569
12591919
10854698
30651555
32929351
23711995
11877444
15888456
18217139
19043829
17980149
|
NR1I2
|
NCOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15331348
16455805
17429319
23160820
18096694
15604093
19171678
23602807
12909012
12072427
|
NCOA1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20608937
15604093
12738788
11003650
11250900
18451880
11867769
15140878
16282588
11165056
11376110
17627277
14715875
10731636
9259327
17363140
11113179
16606617
12630920
9121466
10760302
26487511
23975195
11682626
12714702
9192902
9192892
23874500
11358671
16713569
11014206
10454579
9773983
12554772
9427757
10598586
10409727
9774463
12574227
16957778
|
NCOA1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20682316
21478865
9121466
11124027
15604093
7481822
10454579
10517671
17673910
23975195
11027271
17363140
23602807
15140878
9171239
10082574
11438648
10935544
|
NCOA1
|
PPARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9407140
9626662
10731636
11698662
12163133
15888456
21775429
|
RXRA
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
ESR1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
HNF4A
|
PRGC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17636037
22009745
15331348
15744310
18552123
19846556
15826954
20926756
22155889
15322103
|
RXRA
|
HNF4A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10744771
11027556
|
RXRA
|
PPARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
22205725
7760852
34081964
23711995
10195690
15888456
12562861
|
ERR1
|
PRGC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
33450359
19462000
18063693
12522104
15337744
12181319
18441008
|
NR1I2
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
NCOA1
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
NCOA1
|
NR1I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
PPARG
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
NCOA1
|
PPARG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
ESR1
|
NCOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
NCOA1
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
PPARA
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12941763
16226723
20706641
17261671
18769491
|
RXRA
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
12763030
25609649
20211142
11877444
16504037
17579352
16713569
9065481
22205725
23331499
22363753
10854698
19147680
19043829
12591919
9568716
10882139
10935544
17980149
26260846
21478865
14587029
23711995
9121466
18217139
31547433
7838715
19047629
23275339
21833030
12966085
17312272
11237216
15888456
|
NCOA1
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11698662
10731636
9626662
12163133
21775429
15888456
9407140
|
NCOA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
18451880
9192892
16957778
11014206
16713569
17627277
23975195
15140878
15604093
12738788
17363140
11003650
10454579
16606617
26487511
11165056
10760302
10731636
12630920
14715875
9773983
9427757
9121466
20608937
12714702
9259327
9192902
11358671
10598586
12574227
11113179
12554772
11682626
9774463
|
NR5A2
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
15986123
17463000
23723241
15345050
21445275
24973012
17666587
11103799
|
ESR1
|
NRF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18048642
21486948
23892277
|
ESR1
|
NR5A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23911789
19376833
16091743
|
HNF4A
|
NR1I2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12774017
15331348
12601364
18305375
|
HNF4A
|
PPARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11981036
15912134
19933841
17022998
|
RXRA
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
10195690
12562861
16189514
11237216
10708554
|
NR1I3
|
NR1I2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10924340
15557560
14683479
22363234
|
NR1I2
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
9727070
15604093
11706036
9489701
16189514
26855179
23160820
22976785
|
NR1I3
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8114692
23331499
12130689
12896978
|