Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
STAT1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10558875 22693070
TYK2 STAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15261459 23124025
JAK1 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
CTNNB1 IRS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592430 12782598
CTNNB1 NR4A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 21362399
EGFR CADH5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24658140 25402006
CADH5 PTPRU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CADH5 MACOI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
F19A4 PTPRU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SG1D1 PTPRU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PTPRU MACOI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 27880917
PCDGD PTPRU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZNRF4 PTPRU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CLC2D PTPRU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PTPRU PTPRK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PCDGD PTPRK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PTPRK EGFR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AAMP PTPRU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PTPRU GOLI4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 28675297
SGCA PTPRU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
JAK1 TYK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 8702790 7589562
PTPRU CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16574648 12501215 9054423
JAK1 STAT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32123171 11722592 34521819 32953130 11294897 10982844 15322115 12637327 7690989 14978237 15284024 10918587 7543024 32814877 12817007 34950606 7657660 11839738
EGFR STAT1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KIT STAT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25241761 9355737
EGFR CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9535896 24189400 9233779 11950845
EGFR STAT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 23956138 11294897 15322115 24658140 12637327 7690989 15284024 10918587 25402006 7543024 12070153 12817007 10358079 7657660 11839738
EGFR ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500850 25241761 30898150 17486068 11526509 9461599 23866081 17426253 10572067 11500516 24557338 8665853 15657067 19060928 16516204 19650109 20211985 25315821 23436906 21278786 25898135 32669362 1346931 24189400 21044682 18803307 16843263 28369073 7531698 16713569 17148612 21203579 17307140 1706616 16207817 7797556 12354693 11408594
PTPRK EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16263724
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
ERBB2 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7702605 11245482 11950845
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
JAK1 IRS1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11162588 7499365 9492017
CADH5 CTNB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22720799 17057644 28514442 23243000 22519731 12413882 12003790 18287330 33961781 20123964 9434630 20224040 18662404
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 23956138 12070153 11839738 10918587 11447289 11997436 14967450 25402006 12040186 24797263 15173823 7543024 15322115 10358079 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 24658140 7657660 12817007 31980649 22693070 9355737 19615955 11152457 15284024 15567848 7592750 16488589
STAT1 TNF â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
TYK2 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
TNF IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22328823 22869320 19808894 12110133 11160134 12409308 22266116 21478880 11684411 25352752 24966659 29425748 16754954 25355439 22823902 18443205 24648009 26976796 25645159 23592917
JAK1 STAT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
TYK2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
TYK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 11839738 10918587 15261459 8232552 7543024 15322115 23331499 8780896 10435617 24243840 11294897 7690989 14764663 18988627 12637327 11438544 10748192 14565860 7657660 12817007 23257612 29145629 9355737 11152457 23124025 18389480 10982844 7592750
JAK1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 132.0 1.0 Omnipath 35317858 11839738 10918587 15261459 34950606 11306517 8756628 12244150 8156998 9535918 10748192 7657660 12817007 23257612 27774606 25297818 22306691 8631301 7510216 14963018 15284024 24243840 7592750 10851062 11823427 23331499 7532278 11418623 11722592 18988627 12637327 27387064 8662591 10022928 19088846 32953130 7796299 7504784 23124025 19787091 24058793 20169197 7543024 15322115 18941194 19534553 15978943 14978237 11294897 14764663 21429244 14565860 34228987 25386349 18989459 34521819 9020188 19535621 10982844 21576360 12759422 18508557 8232552 12093291 12040185 20006573 8662795 7690989 20087684 11438544 20035788 11972023 29145629 9355737 11152457 12517932 18389480
KIT STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11839738 10918587 11447289 11997436 12040186 21135090 15173823 7543024 15322115 6321473 11294897 10358045 7690989 15567848 19568798 12637327 14585353 15199124 17496910 11438544 25241761 10748192 7657660 12817007 9355737 19615955 11152457 10982844 7592750 16488589
JAK1 TYK2 â—¼   PHYSICAL_INTERACTION 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK1 TYK2 â—¼   SHARES_COMPLEX 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK1 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702790 19901323 7504784 7589562 15659558 30029643
JAK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15001544 11591769 8756628 7544789 9305869 11162588 9233603 15592455 7499365 12220227
ERBB2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17496910 7702605 7999105 22558232 14517306 11245482 11950845 12040186 19568798 23576562 14585353 23640056
PTPRU CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9054423 19167335 16574648 12501215