Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RIT2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
RIF1 MAD2L1BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRRK2 RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
AP2A1 RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIT1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791108 15632082
NTF4 BDNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
NTF4 BDNF â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
DLST RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PTN MAD2L1BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTN RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIT1 IFRD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAC1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
LRRK2 RIF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
NTRK2 NTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 8621424
NTF3 MD2BP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RIT1 MD2BP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RIT1 RIT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RIT1 CAMKV â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RIT2 LZTR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LZTR1 RIT2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
LRRK2 CDC42 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
RIT1 LZTR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 30872527 33961781
RAC1 LRRK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 21454543
NTF3 BDNF â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33961781 7703225
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
NTRK1 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11733534 25921289 10748052
NTRK2 BDNF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21651720 11855816 9312147
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NGF NTRK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10713102 10490030 9857023 1849459 9083066 14985763 11738045 11729324
NTRK2 NTF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11738045 29997244 25241761 11855816
NTF4 BDNF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10631974 9519408 16189514 25241761 29997244
BDNF NTF3 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
NTRK3 NTF3 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 9488719 10713102 9973222 8621424
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5220560 7744004
NTF4 NTRK2 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
BDNF NTF4 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
PAK1 CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9535855 11157984 21029865 16678097 19596003 23455922 9705280 31871319 25150978 12879077 12606577 10360579 31478661 10684602 8107774 21048135 23175184 18057010 10802735 21167153 15548653 12650940 18426980 7744004 20936779 24276241
NGF NTRK1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
PAK1 RAC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 24625804 19327867 15143066 9535855 17245428 11134022 15673687 15289329 16492808 16551621 21029865 16678097 19596003 26175416 17389360 31871319 24056087 25843002 25150978 12879077 15212766 19693014 11030651 16630611 20810653 8107774 11130076 25468898 29615491 19732720 19270716 21474670 10706722 19277120 10802735 21167153 24172987 21454543 15548653 16002993 12650940 18426980 19961560 11950930 24792722 15688026 7744004 20936779 25819133 15075243 22581261
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GRB2 BRAF â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 BRAF â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
AP2A1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12577067
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
PAK1 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17081983 14580336 21481793 23162742 22105362 18071304 20068231 19036346 18669648 20302846 15378014 27285107 28090172 27345717 19165420 14981079 26555075 19651622 19691289 22567403 11719502 25893302 11782491
PAK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17192257 15710605 10205168 25733387
NGF NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17145710 8155326 9083066 11729324 27908981 22666365 17404842 24224055 25611061 14985763 9290260 9857023 28090201 12067229 23772401 10490030 11114882 27229480 1706478 11738045 10713102 9547236 1849459 9775403 17409494
NTF3 NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27908981 17439940
NTF4 NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11114882
NTF4 NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11738045 767991211855816 25241761 7679912 27908981 9775403 11855816
NTF4 BDNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 7703225 29997244 16189514 10631974
NTF3 BDNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 7703225
BDNF NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 76445409312147 7679912 21849472 27908981 9312147 23331499 9648856 11855816 26899129 7644540 1645620 26740873 9775403 21651720 28679669
BDNF NTF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 7703225
NTF3 NTRK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 1653651 23331499 10713102 7679912 27908981 9488719 9775403 9973222
NTF3 NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27908981 8621424
RALGDS RIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10545207
RLF RIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10545207
AFDN RIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10545207