TP53
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24366007
21552291
|
TFRC
|
TF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20404192
0914898107
|
TP53
|
SAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
ATG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1218395
22499945
|
TP53
|
SLC31A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24799195
21422812
|
TP53
|
PRNP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24339999
19064990
|
TP53
|
STEAP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
19302216
|
TP53
|
VDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
STEAP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
PCBP2
|
PCBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
PCBP1
|
ALOX15
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20884783
|
SAT2
|
SAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
SAT1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ATG7
|
ATG5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11265251
|
TFRC
|
FTH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0913192107
20133674
|
FTH1
|
GOLM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MAP1LC3B
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HMOX2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
ATP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
VDAC3
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MTF1
|
SLC30A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12716893
10952993
|
SLC40A1
|
GOLM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SAT1
|
SAT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
16189514
33961781
|
HAMP
|
SLC40A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
APP
|
PRNP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
FTH1
|
TFRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
FTH1
|
NCOA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
VDAC2
|
VDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
22939629
30021884
|
PCBP1
|
PCBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27684187
23640898
16713569
26344197
|
ATG7
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
ATOX1
|
ATP7A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10557326
12679332
31932435
10497213
|
BACH1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19897490
15734732
|
TP53
|
VDR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16462763
16651407
18431400
|
TP53
|
HAMP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17593032
|
GCLC
|
GCLM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
26653790
26794443
27048822
|
GCLC
|
GCLM
|
â—¼ PROTEIN_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
26653790
26794443
27048822
|
NFE2L2
|
GCLC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9601066
11909699
|
NFE2L2
|
SLC7A11
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17113054
12235164
25092871
|
ATP7B
|
ATOX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17919502
12968035
10557326
16573520
12763797
10497213
|
ATOX1
|
ATP7A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
23028306
22389498
26055706
|
NR1I2
|
SLC40A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19129222
|
TRPM6
|
TRPM7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24385424
14976260
26563869
|
SAT1
|
SAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
ACSL3
|
ACSL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
22939629
26496610
|
FTL
|
FTH1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
8153045
21516116
|
ATG7
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
ATP1A1
|
FXYD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
ATOX1
|
ATP7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
TF
|
TFRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ATOX1
|
ATP7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ATP1A1
|
ATP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
BACH1
|
HMOX1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
4.0
|
1.0
|
ACSN
|
10821856
10874044
12356737
12511571
|
BACH1
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
12511571
17942419
22107958
20083128
14747657
18550526
20501657
23737527
17257585
12356737
18771089
22698995
20345481
14580148
23479260
19439223
22735309
17409198
21982894
15233805
20643109
21555518
|
BACH1
|
HMOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12356737
10874044
10821856
12511571
|
NFE2L2
|
HMOX1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10441483
10821856
10874044
11279008
11909699
12356737
12511571
15521073
16219762
17512463
18761713
19027064
19747488
23850759
|
NFE2L2
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
72.0
|
1.0
|
Omnipath
|
24211276
21382013
23000247
21908612
17942419
18381655
31257023
12745069
22107958
18586007
23904790
24434148
21622983
21808062
22245129
16951197
22370642
23571756
24844779
21658364
11274184
20083128
14747657
15870071
17313370
24759106
20558128
14688281
23525690
21597468
22541814
21443188
21635873
18704831
22521774
16407140
22793650
18006113
22459801
24035498
24140584
23413426
22901690
18771089
24755082
20345481
16551619
23294286
23046979
15122755
16945925
23347118
23738042
21037234
23479260
19056485
19679681
22484158
18202225
24024136
16480751
19931411
20402460
17408602
21982894
25337552
24503931
19454702
23826208
20643109
18567745
|
NFE2L2
|
HMOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10874044
18241676
12356737
18535259
12511571
10821856
|
TF
|
TFRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
11027676
21788477
9546397
6270680
16271884
29302006
14691533
12210842
20404192
16354665
6268632
|
NFE2L2
|
SAT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12020345
10419538
9852135
12804587
11256947
16647090
23943804
|
FTH1
|
FTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
17603935
26653790
26794443
27048822
|
FTH1
|
FTL
|
â—¼ SHARES_COMPLEX
|
|
|
4.0
|
1.0
|
ACSN
|
17603935
26653790
26794443
27048822
|
NFE2L2
|
GCLC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10441483
10821856
10874044
11279008
11909699
12356737
12511571
15521073
16219762
17512463
18761713
19027064
19747488
23850759
|
NFE2L2
|
GCLC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
19282378
14978030
17173895
22212472
19540342
17109620
14500406
15988009
18458092
9601066
16054171
10741850
22459801
15629866
19133322
18721845
16426233
11118612
14985508
18926903
23633659
24024136
18845239
11909699
|
NFE2L2
|
GCLM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10441483
10821856
10874044
11279008
11909699
12356737
12511571
15521073
16219762
17512463
18761713
19027064
19747488
23850759
|
NFE2L2
|
GCLM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19808663
12070177
18535259
16485034
10441483
|
SLC3A2
|
SLC7A11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
18250477
20028852
20414655
26653790
26794443
27048822
2880923
3115975
|
SLC3A2
|
SLC7A11
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
18250477
20028852
20414655
26653790
26794443
27048822
2880923
3115975
|
ATG7
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20562859
22170151
16303767
|
ATG7
|
MAP1LC3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20562859
17145710
11890701
16303767
22170151
11100732
|
PPARA
|
ACSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19710929
10777552
17150915
23426369
|
VDR
|
S100G
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15866228
10417310
11913978
11687634
12520535
|
VDR
|
TRPV6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20227497
16574738
17556365
22563729
17293108
|
MTF1
|
MT2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9084098
11746217
12716893
17363595
|
MTF1
|
MT1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8026472
18337454
18230604
8824273
10952993
11444530
12764133
21035574
16615093
9582278
14998373
8467794
10605938
14627804
16847313
11230134
12716893
12417732
15142038
|