Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EWSR1 ACTL6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ETV4 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18510939 15466854
SMAD3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11906909 16603637
FOXO1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15817464 15632117
STAT3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17089128 20422978
SMARCA5 BAZ1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19092802 19234442
SMARCA1 BAZ1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMARCA5 BAZ1B â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19092802 19234442
MITF BCL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23447565
BRD7 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12489984 6546635
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
PML CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10356361 16007146
HNF4A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17885207
ATF3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22046379 18644986
SMARCA4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
CDKN1A POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678112
CDKN1B CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PAX6 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20053773 17157287
MAX CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313917 18393360
FLT3 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28522571
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
KMT2A CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997566
MRGBP DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
DMAP1 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
DMAP1 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16917507 5218981
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
EP300 CCNT1 â—¼   ACETYLATION ✅ 2.0 0.8 intact 7265510 19387490
EP300 H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
EP300 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
H2AC4 EP400 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RUVBL2 EP400 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218484 16601686
SIX1 EYA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12783782 20110314
FOXO1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17717603 17922034
FOXO1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20338229 15632117
CREBBP FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10973497
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
SMARCA4 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
ETS1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11424091
FOS MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10348347 12173040
FLI1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592502 20153576
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
MDM2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 23839035
CEBPA MYC â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 11340171 20581311
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
NR1H3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10890879 12551904
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
CEBPE MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12947005
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21925595 23722468
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
MYC H2AC7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
PML STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12506013 16189514
H3-4 POLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17099721
SMARCA4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7914327 20224553
SMARCE1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18238828 19785031
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
H2AX SMARCA4 â—¼   COLOCALIZATION 2.0 0.8 intact 7914327 20224553
SMARCA4 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
SP1 SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16288722 15187086
SMAD1 SMARCE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
IL6 STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8662591 8662795
SPI1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24429361
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
CEBPA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24429361
STAT3 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16048438
STAT3 ETV6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15229229
STAT3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 12947115
STAT3 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11889125
TAF9B RUNX1T1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MYOD1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10835425 9448005
RELA TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 8524315
H3C14 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16774833
H3-4 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16774833
TP53BP1 HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16945145
RUNX1 HHEX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28213513
HHEX HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22068426
KMT2A CDKN2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16997566
RELA GADD45G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23681230
SMAD1 GADD45G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
NFKB1 GADD45G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23681230
SF3B4 SS18L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
JUP BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ACTG1 REL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAPK1IP1L EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ETV6 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17606295 19829305
MYCN ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12670915
SMAD3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11711431
FOS PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11774399
RARA PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10361124
PLAU PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721771 16189514
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD3 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15339794
SMAD3 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11331591 21612856
SMAD3 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15044954
SMAD3 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14623893
RUNX2 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19915614 16166639
ETV7 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16722933 11556732
PAX6 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10885745 14673159
CREBBP MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15894584
PTK2 ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16874740 10592173
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HDAC1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16431920
BCL11B HDAC1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
HDAC2 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
HDAC2 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
MAX CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11511535 10508165
RELA REL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211837 10498867
FOS RELA â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
RELA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10488148
SPI1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18227805 12393465
CEBPA CD14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 IL2RB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15084276 18003603
SP1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199305
ETS1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8413220
SPI1 CEBPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8695841 22474248
FOS SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9988737
SPI1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22105598 12032776
SPI1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24503536 19423615
SPI1 CSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SPI1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689920
SPI1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8264604
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EWSR1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8552387 12459554
SS18L1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14716005 15488321
CREBBP TCF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9774110 9388250
CREBBP H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
GZMB ELANE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6796478 9404514
MITF GZMB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1999537 9558376
CEBPA IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10453008
RUNX1 IL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9036972
EPC1 MRGBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 MRGBP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
MRGBP ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
ATF1 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7499271
SP1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12706891 8247540
SP1 PAX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 18314536
SP1 MTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11368903 24010737
SP1 RLIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23650532
SP1 HDAC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16280357
SP1 H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7880446
SP1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10373535 12049196
SP1 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11574690
SP1 SMARCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18243132
ETV4 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8247540
RARA ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11327309
ETS1 HPGD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10650939
ETS1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7731694
FOS ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8557686
MAF ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9566892
CEBPA IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7708053
RARA IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14715249 9153223
EWSR1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21531709 15282325
MEF2C RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
HDAC4 MEF2C â—¼   COLOCALIZATION 2.0 0.8 intact 5215014 11792813
RARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19546303 9507016
MITF FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14737107
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
RUNX1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19686049
NFKB1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100018
NFKB1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21790895
NFKB1 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9294162 9733516
LMO2 LDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17964543 24874989
LMO2 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20676125 21536859
RLIM LMO2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5215168 11882901
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
PAX6 MAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12128206
CEBPA RUNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17431401 5219852
RUNX1 LGALS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19020999
KMT2A RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23817177 22012064
RUNX1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17431401
RUNX1 MPO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
RUNX1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPA ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPA CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
CEBPA MPO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SMAD1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19664780 24692107
SMAD1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17215250 22298955
MET PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521801 16782899
RLIM LDB1 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5215168 11882901
KMT2A MLLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7900984 18952892
KMT2A HOXA10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15941828
KMT2A HOXA11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15941828
FLI1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
LYL1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
RXRG NR1H3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
RXRG RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RXRB RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RARA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11585914
RARA CEBPE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14576045 12032776
CHD3 CSTF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H3-4 GATAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PAX5 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21549805 16482219
PAX5 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15676205
ATF1 ARNT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12527906
CEBPE ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10233885 17347301
EWSR1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16206264 10975680
FLI1 EWSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16206264 10975680
H3C14 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H3C2 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
PAX6 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19651775
PAX7 PAX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18513381 17954266
EWSR1 ATF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9569031 12527906
H3-4 H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC4 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H3-4 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC12 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC21 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC21 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H2AC12 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BCL7B SMARCE1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CCNT1 MYC â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HDAC1 SMARCA5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 PAX5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31941781 21357426
MDM2 ATF3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15933712 29225035 31796886 20592017 34114479
HNF4A SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
MTA2 MTA3 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
ARID2 SS18 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BRD9 SMARCD1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ACTG1 RUVBL2 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
MORF4L1 RUVBL1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CREBBP RXRA â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
BRD7 DPF3 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CREBBP FOXO1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ACTL6A MRGBP â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ACTB ARID1A â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
MYC AATF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
NSD2 BAZ1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22751105 31248990
BRD7 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20215511 35140242
ERG EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 28536097
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
NR1H3 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25962847 33742100
EPC1 EP400 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29028833 27153538
ING3 EP400 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29028833 26496610
BCL7A INO80 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MBD3 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24048479 30415952
MYC RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC SRCAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC MRGBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 35140242
MYC PHF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
H2AX HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31504778 28242625
ETV6 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12527908 11439334
SMAD3 RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10531362 15897867
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 25123934
MYCN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYCN HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31856871 20697349
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
PCGF6 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 12167161
BMI1 CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
AFF1 CCNT1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
RXRG RXRA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
INO80E MCRS1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
DPF3 SS18L1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ACTL6A DPF2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
MORF4L1 SIN3A â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BCL7A ARID2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
BRD7 ARID2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30940648 18809673 24657164 24981860 26344197
DPF3 ARID2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
BCL7A BRD7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
DPF3 BRD7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MAX DMAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 25609649 20946988
DMAP1 SRCAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 24981860 14966270 20946988
DMAP1 EPC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27153538 33961781 14966270 29028833 20946988
DMAP1 MYC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 20946988
MRGBP EP400 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 15647280 33961781 29028833 12963728
MYC EPC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 20946988
H2AX EYA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19234442 27795300
MCRS1 INO80 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17721549 16230350 33961781 24981860 21303910
INO80 NFRKB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17721549 33961781 24981860 25194926 22939629 26344197 21303910
MCRS1 NFRKB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16230350 24981860 17721549
ACTB MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24583282 24798327 17373842
SMAD3 MEN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11274402 16189514
MYC PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 29467282
PML SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 15356634
MTA2 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11602581 12920132 24981860
MAX SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 33961781 25609649
HDAC4 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17011572 10220385 17210713
MAX PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 22325352 33961781 25609649 24981860 29028833 20946988
FOS MITF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 9918847
NR1H3 RXRB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 15604093 33961781 26871637
BCL7A BRD9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
DPF3 BCL7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
DPF3 BCL7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ERG RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
FLI1 RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
DPF1 SMARCD1 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
ACTL6A INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ACTR8 INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ACTR8 INO80B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
INO80B INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
INO80C INO80E â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GATAD2A GATAD2B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DEFA1 DEFA3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF3 MDM2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DPF3 PBRM1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ACTB SMARCD1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DOT1L MLLT1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ETV4 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9194565 14976201 35140242
EP300 FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19064921 21937452 11287611 24069158
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
PML FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9671405 16189514
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
CEBPA HDAC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15713621 22355045 23898169
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6613464 18451879
RUNX2 SMAD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10531362 10962029 17215250 20851880
HDAC2 PML â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HOXA9 KMT2A â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ARID2 DPF3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ETS1 RUNX1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD1 MEAF6 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
BCL7A DPF3 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ACTL6A ACTR5 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SMARCA4 SP1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RUNX1 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14752096 16917507
PAX8 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10924503 35140242
MEF2C EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21556048 9001254
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
PML RXRA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16540467 10610177
SMARCD1 SMARCC1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
SP1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17471507 24396070 21184768 16931573
HDAC1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15653507 22750444 15870198 22116549
IL2RB STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 10602027
RXRA MYOD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9692544 16713569
MYCN SP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18003922 21123453 20697349
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
EP400 MORF4L2 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
MORF4L2 MRGBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
SMARCD1 SS18L1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RUNX2 SMAD1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CHD3 MTA3 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
BCL7B DPF3 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
ACTR8 RUVBL1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
EP400 MAX â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
RSF1 SMARCA5 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ETS1 PAX5 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CHD3 MBD3 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
EP300 FOXO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15890677 24419059 25609649 18786403 11896584
EP300 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10205054 15653507 16713569 33531691 26504087 18782771 30110629 11923478 15735682 15649887 33742100 22116549
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
PER2 MDM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34257372 25103245 30425162
HHEX PML â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10597310 16189514
ID2 MYOD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21209940 9242638
SPI1 CEBPA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16983342 12091339
CREBBP ETS1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
MAF FOS â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21163924 8108109 23661758
DMAP1 EP400 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
ACTL6A ACTR8 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CREBBP MDM2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CDKN1A GADD45A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ACTB ACTL6A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EPC2 MORF4L2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EPC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
ING3 EPC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16387653 33961781 26496610
MRGBP EPC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15647280 17573780 16230350 33961781
HNF4A FOXO1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12519792 19740748
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MYC EPC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 35140242 30415952 20946988
HDAC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
ETV7 ETV6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26186194
SMAD3 MAX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 25241761 12551947
PCGF6 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22325352 33961781 27705803
PCGF6 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
MRGBP EPC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15647280 27153538 17573780 16230350 33961781 12963728
MRGBP ING3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15647280 26496610 16230350 33961781
LDB1 RLIM â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
MTA3 CHD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12705869 28977666 24981860 26344197
RXRA FUS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32814053 9440806 16713569
MTA3 MBD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21258344 24981860 26344197
MTA3 MTA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21258344 24981860 26344197
ACTR5 INO80E â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARID1A ARID1B â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRD7 SMARCE1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
INO80 INO80E â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
INO80E NFRKB â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD1 MORF4L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ACTG1 RUVBL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DPF3 SMARCC1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SMARCC1 SS18 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DPF3 SMARCC2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SMARCE1 SS18 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD2B MTA3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD2A MTA2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SMARCC2 SS18 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDK2AP1 GATAD2B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
IGF1 IGFBP3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ARID1B SS18 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRD7 PBRM1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PBRM1 SMARCE1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GATAD2A MTA3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF1 MLLT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF1 CDK9 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDKN1A STAT3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
DPF2 SS18L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
INO80E RUVBL1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
SMARCE1 SS18L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDK2AP1 MBD2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDK2AP1 MBD3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ACTR5 NFRKB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARID1A BCL7A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCL7A DPF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
INO80E RUVBL2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCL7A SMARCA4 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ING3 MEAF6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ETS1 FOXO1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PML RARA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ACTB SMARCC2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RARA RXRB â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BCL7B DPF2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ARID1B BCL7A â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BCL7B SMARCD1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ACTL6A ARID1B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DPF2 SMARCD2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRD9 SS18 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DPF3 SS18 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HDAC1 RUNX1T1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDK2AP1 GATAD2A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDK9 MLLT1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MYC CDK9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944920 19818711 26687678 11673469 17700062 30415952
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
IGF1R MDM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 12821780 20195357 28092675 18632619 19165858
STAT3 PML â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12506013 16189514
MYOD1 STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12947115 16713569
GATAD2B HDAC1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
GATAD2B MTA2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
NSD2 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18172012 18156491
HDAC2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17312152 18059533 16713569 15713621 17894944 12091390 16036112 12151407 21159880 12176973 20697349
SIN3A MBD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10950960 24981860
SP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18083845 16740634 33572115 7933095
FOS RUNX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11641401 11274169
RXRB RARA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 29892012 16189514 25303530 32296183 16713569 21988832 20211142 15604093 26871637
MTA2 CHD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19703393 28977666 10444591 24981860 22939629 11297506 26344197
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
SMARCD1 SMARCD2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
GATAD2B HDAC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RARA RXRG â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IGF1R MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDK2AP1 MTA3 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GATAD2A MBD3 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
DPF3 SMARCD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MBD2 MTA3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BCL7A SMARCD1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ACTL6A SMARCD2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CCND2 CDKN1B â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ARID2 SMARCE1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DPF3 SMARCA4 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SMARCD1 SS18 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SMARCD2 SS18 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DPF1 SMARCE1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CHD3 GATAD2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
GATAD2B MBD2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ARID1A DPF3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ARID1B DPF3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ARID1B DPF2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ARID2 BRD7 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BRD7 SMARCD1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GATAD2A HDAC1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
DPF2 SS18 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MRGBP RUVBL2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DPF3 SMARCE1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC1 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15454082 9627120 9753732 16147992 10611298
HDAC4 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16147992 11929873
AFF1 CDK9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32707033 32479599 20153263 33961781 21729782 21030982 23602568 26186194 27684187 23455922 24367103
MRGBP DMAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15647280 17573780 16230350 33961781 12963728 26344197
ING3 DMAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 16387653 33961781 14966270 20946988
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
MAX EP400 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11509179 33961781 25609649 29028833 20946988
MYC SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11274368 18003922 17418410 15780936 32115405
MYC PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17146439 15735755 21150319 32592588 30415952
RARA PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11050004 1311253 16189514 16713569 16540467 10882117 17560333 18073335 10610177 12935927 20159610
CCNT1 PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28555140 12727882
PML HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25812002 18073335 11259576 18644863
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
ATF3 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 12718878 20930144
SP1 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11432852 10878024 12228247 22227581 16714330 11114293
SMAD3 RUNX2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10531362 10962029 21986102
HDAC1 NSD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18172012 16197452 18156491 22972034
HDAC1 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 9804427 20585571 28977666 27068747 26496610 33961781 17827154 22939629 9885572 11784859
HDAC1 SPI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 16331260 11593411
HDAC1 MTA3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12705869 23752268 28514442 34026424 22075476 26028330 26496610 21258344 33961781 24981860 18451879 26344197
SPI1 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 9478924
ING3 EPC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16387653 14966270 26496610 27153538
RARA SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18270252 10361124 19401466 16713569
SP1 RXRA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18270252 10361124 10393239 16713569
RUNX2 FOS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11641401 11274169
AFF1 CCNT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20153263 21030982 27684187 19956800 24367103
MBD2 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 24981860 11297506 10444591
CHD3 MBD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 28977666 25123934 24981860
MTA3 MBD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12705869 25123934 26028330 21258344 24981860 26344197
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MORF4L1 RUVBL2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
SMARCA4 SS18 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDK2AP1 HDAC1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ACTL6A MORF4L1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
REL RELA â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
INO80 NFRKB â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK2AP1 HDAC2 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
GATAD2A HDAC2 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
MRGBP RUVBL1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ING3 RUVBL1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC4 MEF2C â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
GATAD1 HDAC1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
DMAP1 MEAF6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
DPF2 SMARCC1 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
ARID1A SS18 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ING3 MRGBP â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ETS1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17213822
SIN3A BCL6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16147992 9765306 9753732
BCL6 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21106671 12594267 15507530
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
MYC BRD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19111069
ACTB CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMAD1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19819988 11786386
EWSR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12560328 18757425 20153576
ETS1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18955504 12740370
MBD2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22241836 22371483 19738071
RUNX1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10617663 23487742 23150456
KMT2A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16169901 19318494 19031738
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20364308 12665587 20037778 17964260 35140242 10944526 9862959 9001254 8621548
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11796223 11062529 9001254
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
MYC EP400 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18413597 17314511 11509179 21150319 35140242 29467282 30415952 20946988
EPC2 MEAF6 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
FOXO1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21471200 21281751 20650891
FOXO1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12391153 15613482
FOXO1 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20088826 17599040 15632117
HOXA10 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12493691 18391971
GADD45A CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A JMJD1C â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAX GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15021909
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
MDM2 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22869143 16713569 12915590 23169665 14507915 19150978 20972456 15195100 12759344
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ING3 MORF4L1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CCNT1 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12944920 19818711 11673469 17700062 29467282 30415952
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
MYC ACTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20123981 17382917 22550094
MYC RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CEBPA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
MYC CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12873812
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
HDAC1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11259576 18644863 25812002 11430826 23563092
SP1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9819401 21360626 24728382 16713569
SMARCC1 SMARCE1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 20829358
NFKB1 STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12057007 25241761 16713569
STAT3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24287565 12147685
CREBBP STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15649887 11773079
H2AX ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HHEX FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20176809 22844093 22874537
NFKB1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11689575 17407600 20352621
RARA SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310893
SMAD3 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15086314 23161884 16619037
SMAD3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055503 24416423
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
CXCL8 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18660381 17375198 11023497
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MBD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 12665568 10471499 10444591 26496610 21258344 33961781 27173435 24981860 27593931 11102443 17634443 11297506 12183469
MBD3 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10444591 21258344 11102443 12354758 19041848 27068747 26496610 25123934 24048479 21670149 17827154 22939629 23752268 12124384 16428440 33961781 24981860 26344197
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
HDAC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15647279 20072153 19062177 11909966 17894944 21636851 18003922 12176973 11896613 15557281 10409740 11517158 15713621 12665570 15722551 17906119 16478997 18850004 16121030 16883603 12091390 15155736 18948152 18059533 16713569 20385359 15528196 16734381 12200149 12847090
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
MBD3 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 20388487 25123934 19041848 26949739 21258344 24981860 17827154 22939629 12354758 26344197
MTA2 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 31980649 19703393 22939629 30737378 20714342 26949739 10444591 21258344 24981860 12493763 19686092 11102443 12920132 18451879 11297506 26344197
MTA3 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12705869 23752268 30737378 26028330 26949739 21258344 24981860 18451879 26344197
HDAC2 CHD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12198550 23752268 22939629 9804427 30737378 28977666 26949739 24981860 17827154 12493763 9885572
HDAC2 MBD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 26949739 10471499 10444591 16410616 21258344 24981860 11297506 25753662 12183469 26344197
RELA MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19530226 20186924
CEBPE SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12032776 12202480
PAX5 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10688639 11179673 21549805
RARA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23321499 16417649 21110951
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
SP1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7811231 8524292 11418664
SP1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8454603 23226269
ETS1 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16861237 18625704 10554042
FLT1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24043698 12023386 29435030
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
SP1 HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10558886 10471823 11802722
SP1 NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19656944 19643914 21123453
SP1 HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18632985 18850004
ETS1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11991951 19829305
ETS1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11857377 18181172 8934537
IGF1R IGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26027733 21645859 8452530
FLI1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21531709 15282325
HDAC4 MEF2C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 32296183 15743821 15964851 12709441 10523670 11504882 11792813 18332106 11486037 11279209
FOS MAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21163924
NFKB1 REL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 27609421 17962807 35140242 33961781 25609649 26186194 15143182
NFKB1 BIRC2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
MYCN HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
REL BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9372964 12414938 10049645
RUNX1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22451420 11283671 17894555
HNF4A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
CEBPA DEFA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10706719
H3C2 MEAF6 â—¼   ACETYLATION ✅ 3.0 0.9 Reactome 18381289 18623064 19187765
RXRA NR1H3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20682316 15722453 9013544 15604093 8621574 12117567
RXRB NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26871637 32296183 15604093
PAX6 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350962 16189514 12756174
RXRA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10744771 11027556
RXRA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19538480
RUNX2 LGALS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18438928 19020999
MBD3 MBD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15456747 10444591 15701600 10947852 24981860 11297506
MBD2 MTA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10444591 24981860 11102443 25753662 11297506 26344197
MTA2 MBD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12124384 19703393 25123934 10444591 26344197 24981860 22939629 11297506 12354758
TCF7 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16575901 16043491 24692107
PAX3 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8633043 20067553
HOXA11 HOXA10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17688409
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HDAC2 SMARCA5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SMARCC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACTB SMARCE1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MAX MYCN â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CCND2 CDKN1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
MEAF6 MORF4L1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
GATAD2B MBD3 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ARID2 SMARCC2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EPC1 MORF4L2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BAZ1B SMARCA5 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
DMAP1 MORF4L1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
NFKB1 REL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ARID1A SMARCD2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CHD3 HDAC2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ACTL6A SMARCC1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ARID2 SMARCD1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CHD3 MTA2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
PAX6 MITF â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16189514 11350962
INO80C RUVBL2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ARID1B SMARCE1 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MEAF6 MRGBP â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ACTB RUVBL2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 MORF4L1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ACTL6A INO80 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ACTR8 RUVBL2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CHD3 GATAD2A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
SMARCD2 SMARCE1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
ACTR5 ACTR8 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ARID1B SMARCD1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
INO80C RUVBL1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
EPC1 MEAF6 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HDAC2 MORF4L1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ACTL6A RUVBL2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EP400 MORF4L1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ACTB RUVBL1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ACTL6A EP400 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
HDAC1 MTA3 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
HDAC2 MTA3 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MBD2 MTA2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MBD3 MTA3 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EYA1 SIX1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
LDB1 LHX3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 12642495 32296183 35140242 33961781
MEF2C PTK2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
INO80 INO80C â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
ARID1B SMARCC2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ARID1B SMARCC1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
ACTL6A RUVBL1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
NR1H3 RXRG â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EPC2 MRGBP â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CDKN1A CCND2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 16765349 5218735
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
CHRAC1 SMARCA5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
MBD3 MTA2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
EP400 MRGBP â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
SMARCC2 SMARCD2 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ARID1A SMARCC1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ARID2 PBRM1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
SMARCC1 SMARCD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DMAP1 EPC1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
INO80B RUVBL2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ACTL6A DMAP1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
INO80B RUVBL1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ACTL6A ARID1A â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BPTF SMARCA5 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
MORF4L1 MRGBP â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ARID1B SMARCA4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
LDB1 LMO2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
EPC1 MORF4L1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EPC2 MORF4L1 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
SMARCA4 SMARCD2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
DMAP1 RUVBL2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
SMARCC1 SMARCD1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
ACTR5 INO80C â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PBRM1 SMARCD1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PBRM1 SMARCC1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
EP400 RUVBL2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
EP400 RUVBL1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
INO80 INO80B â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DMAP1 SRCAP â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
HDAC2 MBD2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 MBD3 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
BPTF SMARCA1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDK9 CCNT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9499409 11145967 15328539 17643375 20562857 9491887 20305087 15713662 19387490 11713532 27684187 14627702 23455922 16980611 26659056 15107825 12588988 12944466 14580347 20153263 22959624 16109377 12115727 21729782 23602568 11282025 30649429 19914168 18483487 24367103 20535204 12832472 19818711 12894230 9872325 23064645 30652970 15713661 21697490 22483617 22939629 32707033 11713533 15528190 15546612 10958691 10617616 10574912 18566585 10465067 24981860 33961781 11689688 17700062 26186194 26344197
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
HDAC1 MTA2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 31980649 19703393 10444591 21258344 12374985 17956988 11102443 27068747 26496610 20127688 11171972 11297506 20585571 21670149 11602581 22939629 18451879 23752268 9790534 26949739 16645043 22863883 28179136 27173435 24981860 33961781 19686092 12920132 26344197
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
RARA RXRA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 9415406 25241761 21988832 16540467 15604093 1310351 10698945 14521715 12052862 9582446 19345331 31700049 7760852 15528208 21478865 9121466 10882070 16769902 15171703 22539306 25303530 7705655 16713569 1314167 16224062
ACTL6A SMARCD1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PBRM1 SMARCA4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PBRM1 SMARCC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DMAP1 MRGBP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DPF2 SMARCC2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ACTR5 INO80B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DMAP1 RUVBL1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SMARCC1 SMARCE1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IGF1 IGF1R â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
NR1H3 RXRB â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ACTL6A SMARCE1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ACTB SMARCA4 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DPF2 SMARCD1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
DPF2 SMARCE1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6613869 18483487
DPF2 SMARCA4 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CREBBP KMT2A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
GATAD2A MBD2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ACTL6A SMARCC2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARID1A DPF2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARID1A SMARCD1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ARID2 SMARCA4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SMARCD1 SMARCE1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
NR1H3 RXRA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ARID1A SMARCE1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ACTR8 INO80 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
ARID1A SMARCC2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
MYCN MAX â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 2006410 23792191 26062444 24859015 10229200 1935896 18003922 18488021 27728805 10597290 29028833 25175806 17289033 20946988
SMARCC2 SMARCD1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ARID1A SMARCA4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RUVBL1 SRCAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RUVBL2 SRCAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 MBD2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTL6A SMARCA4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ACTR5 RUVBL1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ACTR5 RUVBL2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
INO80 RUVBL2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCC2 SMARCE1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ACTR5 INO80 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
INO80 RUVBL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCA4 SMARCE1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKB1 BAX â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 12676992 15613549 21725609 23178297 23572150 7834749
SP1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278953 10510469 11748232
RELA BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18034190 18158998 20056115
MYC BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8845569 11103792 12695333
BAZ1B H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22971774 27449264 26941327 20823147 20965415 19092802 19707781 21326359 25979708 31151422 30013081 19234442 26628370 27220480
NFKB1 BCL2A1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10049356 21725609 23178297 23572150
RELA BCL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10049356 19343319 17000776 11880364 15592513 10733571
NFKB1 BCL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19343319 12665576 17000776 11880364 15592513 10733571
SPI1 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19564417 15892171 31000603
BCL6 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19337254 18648506 15509806 22723377 17392284
SP1 BRD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16792505 18778484 19111069
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK9 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CEBPA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15466360 9442037 12502863 8846917
ID2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17639499 16557594 21900881 16428453 11706002
MYOD1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10373569 25211658 18211587 18521215 16351709 17959144 14749395
FOS CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12705898 12087103 14755691 16141357 10891399 11789587 21864583
RELA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18954936 22305266 23037503 18269916
RUNX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21913213 17438369 19179305 15107836 12391164
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
FOXO1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17609436 23574718 23918930 24769335
RARA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10356361 24821728 21383775
STAT3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23178160 19372587 15286705 18320073 15063116 16923815 9694869 22328012 12438313 11773079 20654581 10023678 19329556 21184768 11114718
SMAD3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10878024 9618481 14755691 10601254 16819512 17516505 10506225 14647420 14583455
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
SMAD3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 9618481 17550342 12545156 11013220 15155580 11074002
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
FOXO1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15084259 19380174 21708191 15084260 21613825 17940099 11154281
HDAC4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18632985 18850004
EP400 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17671089 20548951
CDKN1A CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23443559 26186194 25241761 27107012 8756624 15169570 25416956 16765349 31515488 16189514 32296183
CDKN1A STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 25241761 16189514 10764767
FLT3 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 17254966 28522571 19075005
SP1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9349726 12907235 18355800 10072762 19145069 21131823 22415074 15064717 15951157 16105842 23184467 15899840 12773549 12907249 10542271 16518840 11231912 19433067
FOXO1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21418583 17015685 12359217 12391153 11094066 18593906 19281796 18787071 23160481
FOXO1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11073996 19380174 10783894 20673124 11094066 15668399 17646672 21708191 15084260 21613825 17940099 11994454 11154281
CDKN1B CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25910212 16189514
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
LYL1 EP300 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18160048 21486943 15620361 11840323 27128622
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660747
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EYA1 SIX1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 15492887 28514442 32296183 11734542 12874121 33961781 26186194 15226428
SIX1 EYA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17035528 15226428 15492887 11734542 32296183 12874121
EYA1 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20965415 19351884 19234442 30013081
SMAD3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18391971 15084259
HNF4A FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12519792 19740748
MYC GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15721278 9190899 10913183 15021909 14519204 9811446 21835778
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
MYCN MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15917661 15644444 15927364 19649205
MDM2 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 25241761 28092675 12821780 18632619 17303558 19165858 36042202 20195357
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
MEN1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11526476 14508515 16713569
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16596619 21988832 10229200 17471507 26267534 15572685 18003922 20382893 35140242 17418410 25609649 16352593 31767764 17072308 17289033 10918583 9528857 14749374 21807113 19623651 18620061 25522242 32296183 16140957 16705173 19578763 26496610 12584560 17157259 17643117 24951594 20946988 10465786 12706874 12821782 9184233 17353931 10611234 32140074 8266081 20691906 16410719 21150319 10593926 12660246 27859590 12553908 8224841 10319872 2006410 16287840 16606833 23816886 9708738 17314511 9886493 27705803 33298911 33961781 20936779 12824180 9680483 17700062 29467282 30415952 12391307
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MMP9 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
MYC CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15681429 17082780 7556187 8076602 20097210 12695333 15867211 19259613
MYC H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18414489 22055461 12695333 11085504
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
TCF7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
PML SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 15356634 16189514 18988627
SMARCA1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23609547 24285714 20015969 17023429
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
RSF1 SMARCA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 18519663 20923775 26666816 12972596
IL2RB STAT3 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
IL6 STAT3 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
FLT3 STAT3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10477595 14670306 15253381 16418395 25215878 8920882 9268501
STAT3 MMP9 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 FOS â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
STAT3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17204573 14737107 12640143 12600988 11685114 8071311 15040450 16293640
STAT3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22927445 22363173 19797626 22547075 18765795 18616672 23954444 20493732 19751774 22105366 10391682 24315995 20930550
IL6 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 26291658 30185178 20185553 28222632 11322950 30143645 27074565 28687744 21538419 16278387 28128332 24496235 26166037 21625597 20371721 25750173 29330478 19962667 26010889 24513872 29702530 25881314 24078775 27866206 24619648 27840174 19380824 24661007 11728826 21619877 11056211 17142955 26417930 29270528 18611949 25452693 27795451 16520748 26843613 29807795 21442031 26893580 26061710
HDAC2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15653507 25241761
IL2RB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16189514 10602027
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
H2AX TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 20075863 18001824 21317870 12447390 17024177 18001825 21566653 12607005 12697768 21623170
SP1 CDKN2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18642058 15107822 22504641 12077144
KMT2A HOXA9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 15941828
ID2 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9242638 8380166 21209940 1922066
PAX7 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18854138 15501225 17548510 18508329
PAX3 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20605921 11262400 10529415 20978076 18508329 18854138 14732408
MYOD1 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10082523 1662816 9148896
CREBBP MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10944526 16713569 11463815 9238849 2176177
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
MEF2C MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15743821 9418854
KDM6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24561908 17713478 20123895
PLAU PTK2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
SP1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23978400 10361124 21567400 21076612
ETS1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16127276 15247905 11556732 20645833 9185999 10211993 8683934 18772901
RELA PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11689575 20352621 18226221 19165610 22797919 20018891 10467400 9914486 17407600
ETV4 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1330539 8570190 9295342 11676474 8761947 7760840
SMAD3 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 ETS1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14754879 12672795 18804287 12853969
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
SMAD3 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 25241761 16189514 12551947
SMAD3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21986102 10962029 15084595 11331591 10531362
ETS1 MMP9 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 10048576 15001984 15003528 15111329 15181457 16079281 16391805 16556862 16682805 17615296 17872466 18337545 19208835 19564415 20589835 21041997 21081489 21317430 22439866 22608498 23691193 24376839 7512751 7528107 8844971 9157999 9811054
SP1 MMP9 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
FOS MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16554298 11774399 21238464 18809380 23508111 21474819 15319566 10935492 21940623 24173318 16882662 21047770 9136992 23955082 23176293 12032150
NFKB1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 18298869 12105194 11376631 14600595 17673602 17922642 15605368 14755547 20332461 18357389 17186550 11060311 18566231 9679762 16687076 17121934 18843978 21963718 18056465 20103608 17174275 15536164 19303700 17158602 7860222 19539355 9500201 19783786 18567920 15175338 17498959 10359016 18801463 19454280 19662350 12193473 16014933
ETS1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22270366 15949416 16722933 11556732 22206665 10949659
RELA MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 18298869 12105194 11376631 14600595 17673602 23423566 17922642 15605368 14755547 20332461 18357389 21502320 17186550 11060311 18566231 9679762 16554298 16687076 17121934 15086314 18843978 21963718 18056465 20103608 21238464 17174275 15536164 18028425 17158602 17590163 19303700 7860222 19539355 9500201 22587999 19783786 18567920 15175338 17498959 19616091 10359016 18801463 19454280 24755270 19662350 12193473 16014933
SP1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8226872 24755270 18028425 9514098 9520415 23799155 20529870 21840940 7860222 17049831 21963718 18357389 9150367 11060311 19616522 11830485 9748266 20638438
ETS1 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10048576 16391805 17615296 15111329 19564415 9157999 16079281 21081489 21041997 15181457
CD14 IL6 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
REL IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17513725 17982049 11564778 11160296 1372388 19122653 12426000 9171095 8910763 16688168
ATF3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20203264 24317040 17785797 24951825 20351107 22105779 16688168 18942706 17766920
SPI1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15013752 23509362 18680724 19502584 25567680
FOS IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10037779 10542237 9671466 2511437 25567680 20351184 24994901 11356008 11028561 12667961 18502099
RELA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 114.0 1.0 Omnipath 26596471 19124729 10373597 9523851 23595969 28270510 21537341 17982049 15226358 18243142 12200447 20371366 24664372 23874122 14532843 18942706 10975857 21278793 10469356 22547075 17490702 11459775 23335080 10569191 19707556 19687301 7499267 8290595 23857586 24676671 18061164 11058167 12887736 15013753 15158360 22661093 20935672 20511231 17350185 10903137 16112536 27413250 21810609 16984731 16166627 18469854 12881425 24012417 23386688 22105366 8752656 12176740 27371733 22578249 18057724 20351184 10329846 19164127 10542237 11564778 20221401 15517885 19122653 20534538 7876168 27211851 9516466 18996370 8824277 18310089 21104991 25888873 12359431 11327783 20066113 20100571 19703987 19469019 21106671 16960103 18502099 16043358 21996739 20650996 22021035 11120852 12672795 12058956 18483242 22189669 14976218 17495236 11007957 21131967 11975924 27337441 9182853 10963848 17040605 11504280 15756023 10823821 17932106 19966855 20696864 12177065 8679226 9199307 17196927 20457835 21098092 17532054
CEBPA IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15158360 10748205 11975924
NFKB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 71.0 1.0 Omnipath 17513725 18061164 12058956 24337575 19124729 15611045 11058167 9523851 15517885 12887736 15158360 7876168 17495236 25549935 17982049 15241416 18243142 9516466 2405250 18996370 8824277 18310089 24664372 15749903 10903137 16112536 14532843 11327783 18942706 11975924 20066113 16984731 10975857 11160296 19703987 22895549 10963848 10469356 22547075 17040605 11459775 17490702 19469019 8247545 11504280 15756023 10569191 10823821 20696864 12907458 19707556 16043358 11035101 12176740 11302724 8679226 8725624 22578249 8752656 17196927 17532054 12727841 18057724 7499267 10329846 9199307 9502421 19164127 11120852 24676671 11098847
MAF ITGB7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14998494 17490615
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
RELA CXCL8 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15079071 15536066 17550372 19171876 23430059 8383323 9743347
CEBPA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22685373 25119735 8999951 18199703
RELA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 129.0 1.0 Omnipath 12820969 24337575 15289496 9405619 9698090 20038977 15057743 21665565 24260304 10817569 14631383 10969814 15005855 19668231 16325549 19732956 8207232 18281166 27856305 23894194 9388261 26340924 10975857 10745031 20194077 10928981 16553947 17565687 16764699 22848596 15531761 16105834 16803583 9510190 15355994 18221537 12643600 20053934 11716760 8617886 12218154 12707271 23637609 27076634 8878392 17917246 12163591 16829531 16818736 14670967 12038622 15958549 18362169 8413215 19734226 23386688 11297551 15950427 17362989 16455661 27371733 11953364 8413306 18074095 11973337 18786178 19376732 19837667 17276517 15517885 11342414 18669446 7876168 15350531 14645117 22891766 18034886 11564889 12748173 17586662 18996370 15223809 17041011 12485925 16004996 15079071 21343296 26618242 18435575 17636245 22340043 19173296 24634218 11120852 10477716 21343177 12058956 17045242 19786024 24048734 24770886 10202011 18309103 11864912 21131967 19064995 10530453 12716652 16418726 28283022 18723827 17040605 21255844 15615716 17932106 19966855 20696864 15387324 21451502 15722553 15879558 12855659 12883201 15688424 18045535 10506755
FOS CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11973337 18317936 12218154 22095787 12748173 10969814 15005855 17586662 16818736 24048734 14686613 16846747 15057743 15615716 8999951 25567680 19173296
NFKB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 9510190 12058956 11973337 18786178 17045242 15289496 16701870 19376732 19837667 9698090 17276517 11512674 19786024 20038977 10202011 15057743 15517885 12643600 11342414 7876168 15350531 18034886 11716760 11564889 11864912 12218154 12707271 10969814 12748173 14631383 16325549 17586662 18996370 19732956 17041011 10530453 18281166 12716652 16418726 12485925 16004996 9388261 8878392 17917246 10975857 10745031 10928981 16553947 16818736 14670967 18435575 12038622 15958549 17040605 8413215 21255844 22340043 1401924 9452482 16764699 11297551 15950427 15387324 15879558 16105834 11953364 15688424 18074095 8413306 11096450 16803583 10506755 11120852 10477716
MAX CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
RELA CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9414129 7636192 9190901 11418664 18230685 9596659 8135780 21071440 14741709 11395507 8934574 18285351 10608823 18056447
RELA BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15231833 15050749 19343319 17673602 18226221 23250755 17000776 11880364 21279667 21765477 10733571 18566231 12010810 15723831 10823821 11297551 16291753
RELA BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 12714587 15756023 12010810 18566231 16453001 20103608
RELA CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10586028 12574356 15949284 19164127 15895390 18929846
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
RELA CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11313274 17031478 19164127 9733827 10075983
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
CD14 ITGAM â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10201950 16751103 3537192 2462607
CD14 FLT3 â—¼   DOWN_REGULATES ✅ - 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
SP1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11698458 17203216 12213324 7512565
ETS1 IL2RB â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15001984 15111329 15181457 16391805 17615296 21041997 21081489 22608498 9157999
SPI1 FLT3 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10734131 11672593 11964313 12032143 12803886 12811837 16283355 16418395 20510871
RUNX1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23817177 19339695 20972335 24037986 18316480 19208846 17994017 12576332
SP1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12706891 22734486 10446912 7478579
CEBPA SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17671233 24429361 14636649 20972335 12949251 14592841 12032776
SPI1 FCGR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12393465 7869026 8035786 12130529 15304324 14734612 10820245
SPI1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10823830 11481336 14962802 19801646
SPI1 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17116688 8264604 9506963 8302571
SPI1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10523830 9858537 23056458
SPI1 ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9689920 8756629 16247445 9192779 14732495
SPI1 ITGAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8955212 19747912 12393465 19502584 9295016 15163413 8095266 25005557
CEBPA SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10397723 12091339
SPI1 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8095266 15676205
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
SRCAP CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11581372 10347196
ETS1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9190901 7478534 8611694 15907486 12475968 15123671
NFKB1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 11418664 12760745 8135780 8934574 14741709 18285351 10608823
FOS CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 1900839 8135780 11509589 9028942 12432566 7579683 8631792 9862439
REL CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9414129 11418664 8152309 8662666 8934574 8660380 9185524 24899500
IL3 CD86 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
IL3 CD40 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
RUNX1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11997340 9036972 20506188 15735013 10023677 8180380
ETS1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8704203 12387738 25861992
CD40 CD86 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
NFKB1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10586028 15949284 19164127 15895390 18929846
SP1 MPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057865 17521322 8662930
SP1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10720440 21447702 7497000 15345673 17170218 7491107 17049831 17014845 10982795 17486080
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
SP1 PDGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15297375 9453298 9321833 9351401 22964636 7499234 10364563 11823426
SP1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160217 9339900 19753117
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
SP1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8940191 8184747 11026572 14593001 12217897 8910531 7896792
SP1 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10452548 21437359 2172788 18419748 9851700
SP1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17626239 10082538 9528985
SP1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12200149 11517158 15247904
SP1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14567977 22815527 21123453 14645238
SP1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11910354 12473536 9223667 15067326 21831840 17283128
ETS1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9349499 8262053 1722028
IGF1 IGF1R â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11237532 12181198 17145802 19631971
IGF1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21798082 23331499 8452530 21071413 12067807 1852007 21645859 8408032 14604834 19258508 11287679 23675206 19029956 2877871
IGFBP3 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10823924 11600567 22578544 1383255
HDAC4 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12709441 15743821 11279209 15964851 10523670 23752268 11792813 11504882 18332106 10737771
NFKB1 BIRC3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21725609 23178297 23572150 9294162 9733516
NFKB1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15231833 15050749 19343319 17673602 17000776 11880364 10733571 9733516 18566231 12010810 15723831 10823821 11297551
NFKB1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513725 11313274 19164127 11027342 17031478 9733827
NFKB1 BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 15756023 9733516 12010810 18566231 16453001 20103608
RSF1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15242768
CD40 BIRC2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
CD40 BIRC3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
MITF CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14962802 11481336 17105730 11425859 10750559 11818452
PAX6 MAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11222774 21998302 14521912 19223471
RUNX1 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16007221 17589498 9209363 8577711 8585955
CEBPA ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17360796 19620402 8756629 16247445 12949251
MET PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15611085 29435030 30134553 22188814 24043698 16782899 14572662 15247219 15561106 20802513 15598735
HDAC4 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22298955 15537544 16613856
TCF7 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
KMT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12453419 20210320 24680668 29897600 31485071 20541251 24235145 20452361
RXRA NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20682316 12117567 23331499 15722453 15604093 21071413 9013544 18988627 10890879 8621574
RXRG NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25910212 15604093 25416956 21516116 31515488 32296183
RARA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7556191 19538480 12935977
RXRG RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 25910212 25303530 23331499 20211142 15604093 21071413 10529278 21516116 25416956 31515488 16189514 32296183 16713569 18988627 29892012
RXRB RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 26871637 25303530 23331499 20211142 15604093 1310351 21071413 10721822 31515488 16189514 32296183 16713569 18988627 29892012 1310259
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
PAX3 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10982026 22290434 10480898 19074888 19403660 9500554 19026785 20925909 11237412 10942418 10644012 21965087 21519923 11830592
MITF PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9466887 23610061 17277739 15978250
MITF MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1999537 17371876 19067971 20068147 20067553
REL BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12414938 23271966 11880364