Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JAK2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213490 11163768
JAK1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213490 11163768
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
SHC1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
CBL ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
TLR2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17126326 5219377
EGFR CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EPOR CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11443118 11124936
ERBB4 CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
JAK2 CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11443118 11124936
JAK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9670964
EPOR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 8400282
ERBB4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16912174
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
PDK3 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
STA5A PDK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STA5A PDK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PDK3 ODPX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR2 ODP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 25604459
BTK STA5A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 7925280 11413148 8617237
STA5A KLHL7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STA5A ODP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
STA5A ODPX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
TLR2 STA5A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
SHC1 EPOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 8400282
ODPB PDK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ODPB PDK3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PTN1 EPOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14527337
STA5A CD3Z â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 9880255
STA5A ODPB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
STA5A ODPA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
BTK CBL â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
STA5A BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12459499 26970274 16713569
PTN11 CBL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17330819 18519587 11157475
CBL STA5A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23533197 12193575 25814554 33767425
SHC1 STA5A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23397142 10996427
STA5A JAK3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18250158 10037026 9047382 16189514
EPOR STA5B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15644415 8977232
PTN1 STA5A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12237455
PDK3 PDK2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
ESR2 STA5A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11682624 16189514
PTN11 EPOR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7534299 8639815
JAK2 BRCA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 11163768
JAK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 11163768
ODP2 PDK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12816949 16189514 11978179
PDK2 ODPX â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12816949 16189514 12573248
PDK2 ODPA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11485553 27505672 12676647 34079125 11486000
EGFR STA5B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16729043 10558875 11751923 22729867
EP300 STA5A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21988832 26504087 9989503 30110629 9773981 14726487
CRKL PTN11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9660791 9344843 23397142
MK01 ESR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9528769 11358671 12093745
IL2RB JAK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
JAK2 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24240702 9363897 10635327 16273093 23838182 10358079
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
SHC1 CD3Z â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8647168 16189514 8656061 7544002
STA5A IL2RB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20816854 16189514 10602027
STA5A ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15304355 11682624
STA5A ERBB4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16729043 22584572 15534001
ERBB4 PTN11 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16729043 22973453 28065597
JAK3 CD3Z â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11349123
ODPA ODPX â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 22939629
CRKL EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBL SHC1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
NMI BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11916966 16713569
TLR2 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17126326 24658140 25402006 31980649
EGFR ERBB4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25140053 23153581 25315821 16061658 10572067
EGFR CRKL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 25402006 18271526 25754235 16729043 23397142
NMI STA5A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 9989503
SHC1 IL2RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 8294403 10602027
SHC1 MK01 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23584453 10996427
STA5A JAK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11722592 9047382
PDK3 ODPA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 11485553 27505672 12676647 33961781 34079125 11486000
ODP2 ODPX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14638692 16189514 21988832 31536960 22939629
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
BTK CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10826882 10427990 9408950 7629518
STA5A EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24135280 31980649 24658140 22729867 25402006 16729043 10358079
PTN11 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9756944 22973453 20473329 7673163 28065597 14560030 24935154 11223155 16273093 8959326 12270932 16729043 7588774
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
CRKL STA5A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9837784 9845531 9657743 11167825
ERBB4 SHC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9019162 22973453 24658140 16273093 16729043
SHC1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
PTN11 JAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8995399 9794795 11036942 12270932 12403768
JAK1 IL2RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7973658 9774657 7973659 8700888 8041779 9553136 20816854 12133952
JAK1 BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9178903
JAK2 STA5A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8617237 11413148 9575217 7925280 34197875 9047382
ODP2 PDK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 11978179 33961781 17683942
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
STA5A MK01 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10194762 25241761 10996427
PTN11 STA5A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10617656 12237455 16189514 12060651
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ODP2 ODPA â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 14638692 16189514 34079125 22939629 26344197
ERBB4 SHC1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
SHC1 JAK2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 7535773 9126968
STA5B STA5A â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 28514442 9528750 33961781
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
JAK2 STA5B â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9575217 24354892 9047382 12538627
ODPX ODPB â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 16189514 33961781 26186194 7864652 22939629
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
SHC1 CBL â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10570290 10025673 16713569 8621719 9541596 8662998 9461587 9434624 9234717 8950973 19380743 15677445
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
CRKL EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11443118 9344843 9129019
PTN11 JAK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7559603 8995399 9442080 8639815 8912646
PTN1 JAK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11694501 11970898 15821101
JAK2 EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 14982882 12441334 11779507 8343951
STA5A EPOR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15644415 8977232 10374881
CRKL CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9162067 9129019 16982329 9590251 8621483 25814554 10907644 10608804 15107835 7545163 9092574 9195915 12244174 18835194 9311917 8524328 16503409 24886428 10657627 14604282 9820532 8662998 9461587 9851874 11399323 9344843 11157475 10204582 9660791 15556646 8978305 11553620 8626543 9988765 33961781 11263968 15358160 11133830
SHC1 EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7518560 8034616 31980649 23956138 9544989 8610109 7542744 25402006 16729043 8665853 15657067 9742218 24797263 10049786 12577067 9756944 23799367 25187647 20935677 10766863 18271526 11408594 7506413 10635327 10595738 24189400 19531499 7542991 20473329 24430869 8662998 9020193 8887653 16273093 25754235 9388490 31959764 26551075 16713569 22973453 24658140 11196191 28065597 20067773 8810340 21278788 30544639 9130710 11370743
EPOR JAK2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
SHC1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
EGFR PTN1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 25796184 12573287 31980649 7693694 8621392 9050838 24658140 9355745 11506178 7540771 25402006 10889023
ODPA ODPB â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 16189514 31536960 12651851 33961781 34079125 26186194 7864652 19081061 22939629 29128334 26344197
ODP2 ODPB â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 14638692 28514442 16189514 18206651 33961781 26186194 26344197
CBL CRKL â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CRKL CBL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL CBL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL CBL â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
EGFR CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 23397142 18271526 24658140 25402006 16729043
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
SHC1 CRKL â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 CRKL â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
IL2RB SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8294403 8700888 8643566 10602027 16189514 24737791
ERBB4 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16273093 16729043 24658140
JAK2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9126968 7535773
JAK1 IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
JAK3 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11641425 19901323 20135364 17259970 12207328 10825200 11909529 15659558 12559972 9553136
JAK1 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9774657 7973658 8700888 12133952 8643566 10373548 7499411 8041779 7973659 9553136 7973657
JAK2 EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10660611 12441334 7559499 8343951 18672044 11779507 12027890 11443118 12524467 9030561 9573010 15212693 10579919
JAK3 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 7693677 16189514 10825200 7973659 9553136 7973657
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
TLR2 BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518