Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
PRIM1 CTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
POLA2 CTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
PRIM2 CTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
POLA1 CTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
POLA1 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
POLA1 PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 TEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
POLA1 PRIM2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
POLA1 POLA2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
PRIM1 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
MFHAS1 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PRIM2 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA2 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
POLA2 TEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
PRIM1 POLA2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
PRIM2 POLA2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
PRIM1 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
MFHAS1 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PRIM2 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
GOLGA2 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
STN1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
STN1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TERF2IP ORC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16799465 5218770
TERF1 ORC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16799465 5218770
TERF2 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
PRIM1 TEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
TEN1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRIM2 TEN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 30026550 29774655
PRIM2 PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
PRIM1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRIM2 PRIM1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
GOLGA2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LGALS14 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TXN2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TERF2IP TERF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
TERF1 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
C14orf119 STN1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
ORC2 BRCA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17525332 25184681
CCG5 CTC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CNPY2 CTC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI CTC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TFAP4 CTC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TFAP4 STN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CCG5 STN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GEMI STN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CNPY2 STN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STN1 PRI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
STN1 DPOA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STN1 GRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CCG5 GRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MKRN3 STN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
BRCA1 TERF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34112789 19797051 29656893
BRCA1 TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34112789 25184681 19797051 29656893
STN1 SMC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 SMC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 UBP33 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 CYTSA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 ORC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 MAGG1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 NSE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 CL069 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 UBP47 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 LRWD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 UBP15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 NCOAT â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 YQ023 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19854130 32296183 28514442 33961781 26186194
STN1 KIF3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 F136A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 UBP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STN1 ORC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CTC1 TEN1L â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19854130 28514442 22763445
MAGG1 SMC5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 29225034 26344197 18086888
STN1 TEN1L â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19854130 32296183 28514442 22763445
ACD TERF2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15231715 16880378 15383534
TPP1 CTC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25172512 22763445
TPP1 STN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25172512 22763445
ARH STN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 25910212 33961781 26186194
LRWD1 ORC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20850016 22935713 26496610 31160578 33044890 22939629 26344197
LRWD1 ORC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31160578 22939629 26496610
LRWD1 ORC3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ACD TERF1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ACD TERF2IP â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ACD TERF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15383534 15231715 16880378 26496610 33961781 26186194
LRWD1 ORC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
STN1 CTC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19854130 28514442 22763445 33961781 26186194
MAGG1 SMC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29225034 27427983 26496610 18086888 33961781 26344197
TERF2 ORC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16799465 18761675
MKRN3 TCHP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
POLA2 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 8223465
MAGG1 NSE1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 29225034 27427983 26910052 18086888 33961781 26186194 32389690 21364888 26344197 20864041
STN1 TEN1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
LDLRAP1 STN1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CTC1 TEN1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
NSE1 SMC5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 18086888 33961781 26186194 16055714 26344197
NSE1 SMC6 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 14701739 26496610 18086888 33961781 26186194 32389690 26344197
SMC5 SMC6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15601840 26496610 18086888 33961781 32389690 11408570 26344197
ORC3 ORC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15910003 20850016 12614612 26496610 16549788 31160578 11395502 17525332 10402192 11323433 12004060 22939629 17716973 26344197
TERF2IP TERF2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8286516 21829167
NSMCE1 SMC5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NSMCE1 SMC6 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
DPOA2 PRI1 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 16189514 14681455 33961781 12138179 22939629 26344197
TERF2 TERF2IP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SMC5 SMC6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PRIM1 PRIM2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
POLA2 PRIM2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLA2 PRIM1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ORC2 ORC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
NSMCE3 NSMCE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 21364888 32389690 20864041 27427983 18086888 26910052
SMC6 SMC5 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 15496928 15549137 15655342 16697054 18001825 18171670 18212739 19217833 19270065 19490890 19772495 19847258 20021983 20064462
SMC6 SMC5 â—¼   PROTEIN_INTERACTION 14.0 1.0 ACSN 15496928 15549137 15655342 16697054 18001825 18171670 18212739 19217833 19270065 19490890 19772495 19847258 20021983 20064462
TERF2 TPP1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TERF2 TPP1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TERF2 TERF2IP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 17145710 19651898 15316005 27214791 10888888 21217703 19287395 15383534 26496610 23086976 19164295 15100233 16880378 26450775 21829167 10850490 28082411 23307557 21044950 14565979