Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F1 CDC45 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10692433
E2F1 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24076372 18439978
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
CDO1 TOPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CBLN4 TOPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PLK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25483079 24067368 31730000 29656893
PLK1 TOPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26811421
TOPB1 PML â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19023333 12773567
TOPB1 TP53B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11756551 29656893
PARP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 25252691 26831064
TOPB1 PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 17340632
ESR1 TOPB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
BRCA1 TOPB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23157317 19766185 29656893 33010150 25184681 16391231 11395493 12697828 23901102
TOPB1 TICRR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30695077 21700459 30295604 23704573 23696651 28439015
TOPB1 CDC45 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20065034 17887956 23364835
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TOPB1 MDC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21482717 24239288 27590578 29656893
TOPB1 FANCJ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23157317 33010150 24573678 30295604 16391231 21127055 20159562
TP53B BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22884692 31009828 12364621 17525332 26831064 21552324 18001824 29656893
MDC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 19766185 15569676 12611903 17525332 12607005 29656893
PARP1 E2F1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20133863 14627987
MDC1 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30179224 18986980 17925396 12607005 29656893
PLK1 TP53B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25659891 26291670 25607646 32707033 20126263
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
FANCJ BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17664283 19369211 17525340 30257991 25184681 22792074 17525341 28911102 23530059 15125843 26831064 14576433 29656893 18717574 15133502 15208681 18285836 20159462 25252691 14578343 21240188 11877378 18628483 28398198 19452558 17596542 17581638 14576432 23157317 17525342 27399284 16713569 20173781 24573678 22032289 20681793 15242590 16391231 11301010
TOPB1 E2F1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14576432 14576433 12697828 17006541 28439015 20413589
TOPB1 RAD9A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26312135 20545769 22925454 17575048 26088138 30295604 25091155 25602520 12941802 11395493 17006541
TOPB1 ZBT17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17006541 12408820 18923429
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 E2F1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 E2F1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
E2F1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10660629 23285190 18660752 19466541 17106239 20068145 23108140
E2F1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244350 18660752 18319725 11278247 12697828 16713569 12909625
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
PARP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14627987 20133863