Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BAX P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32064756 25241761 21712378 25115399
BAK CH60 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12070120 16189514
MCL1 BAX â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17525735 5219960
B2CL2 BAK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 25416956 10381646 25115399
MCL1 B2CL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10837489 15077116 7937747
BAK BAX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15901672 16439990 17289999 33961781 21712378 11571294
BAK VDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 12881569 16189514
BAX BID â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 15574335 20956295 23374347 17289999
P53 BCL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21624955 30683842 21597459 32064756 19521340 12667443 9194558 16443602 23316052
BAK BCL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20836993 14980220 26004684 32064756 9463381 11728179 11206074
B2CL2 BID â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15694340 16697956 17289999 33961781
BID MCL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15694340 16697956 19074266 15637055 21613222 33961781
MCL1 BAK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15901672 26045051 15637055 27818144 19148187 32296183 10579309 22516262 19968986 23680104 18040043 21132008 20836993 17097560 20023629 19483105 15077116 10837489 21613222 33961781 26186194 26004684
BAK P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 32064756 15077116 27818144 25408501 21712378
BAX BID â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
BCL2 BID â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
B2CL2 BAX â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 18981409 21199865 17289999 33961781 10381646 25115399
BID BAK â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10950869 23782464 23604079 25408501 12624108
MCL1 BAX â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 18981409 19968986 21458670 15077116 21199865 10837489 33961781 26186194 17525735 21566062 19148187
BAX B2CL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25241761 18981409 32064756 21199865 17289999 19427863 9824152 27684187 18547146 9194558 24814347 21671007 21458670 28202514 26496610 12853473 16151013 12137781 9388232 9742125 22072718 19074440 11283018 21567405 15131699 9111042 14963330 9153240 9027312 21852238 33961781 28760928 26186194 25115399 17525735 29749471
B2CL1 BCL2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 14980220 11583631 12137781 7937747 33961781 26186194 18835031
B2CL1 P53 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21900206 16189514 14963330 16713569 30683842 32064756 16151013 26556313 20837658 24474649 25115399 24814347 12667443
BAK B2CL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 15901672 32064756 10085290 11175750 14596824 32296183 31467278 15292519 23055042 22516262 26264872 12137781 23680104 19060904 20836993 9362454 34098062 17446862 29997244 9027312 32814053 33961781
BID MCL1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
BAX BCL2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BAX BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21778226 18981409 15899854 32064756 10620799 21199865 17289999 9194558 8358790 21671007 16642033 21458670 22262057 9388232 10716992 20865015 14980220 9111042 24141421 17097560 15231068 9463381 33961781 17525735 29749471 23479509 26004684
BID BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16697956 15694340 19074266 11583631 9727491 9463381 15520201 14681455 17289999 18835031 12624108
B2CL1 BID â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 15694340 16697956 14963330 15574335 25241761 14681455 17289999 33961781 19074440 24814347 15721256
BCL2 BAX â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
BAX MCL1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
BCL2 BAX â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
BAX MCL1 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
BAX MCL1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
BID BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 20956295 17289999 25241761 19968986 15574335 10629050 19062087 10949027 12242151 23374347 14730312 17520191 8918887
MCL1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 21458670 18981409 26186194 14766748 17289999 19968986 15077116 19062087 21199865 17525735 10837489 14730312 19148187 21566062 15713684
BCL2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 22705850 18981409 9463381 21458670 17097560 17525735 8358790 10620799 26004684 29749471 9388232 21199865 17525161 22262057 21778226 15486085 17289999 9111042 12419244 9194558 15231068 10716992 8183370 14980220 9115213 21671007 16642033 23479509 10677502
BCL2 MCL1 â—¼   DOWN_REGULATES ✅ - 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BCL2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18835031 17145710 9463381 16697956 17289999 19074266 12624108 11583631 9727491 15520201 8918887