VDAC1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907555106
19706527
|
FKBP8
|
BCL2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
10409669
20139069
|
MCL1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8095158
21139567
|
MCL1
|
HRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15031724
23850759
|
MCL1
|
BMF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
11546872
23850759
|
MCL1
|
HRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15031724
23850759
|
MCL1
|
BMF
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
11546872
23850759
|
BAX
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
32064756
25241761
21712378
25115399
|
BIK
|
MCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
B2L11
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22516262
19427863
|
BAD
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19427863
17274640
|
BAX
|
PRKN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28760928
32929329
|
RNF4
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29180619
32296183
|
CFLAR
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21474069
18559494
|
VDAC1
|
BAP31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31206022
26344197
|
BNI3L
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10467396
16189514
9973195
|
B2CL1
|
DYL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10198631
33961781
|
BAD
|
BCL2
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15694340
|
NALP1
|
CASP9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11113115
11076957
|
B2CL1
|
PDS5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
B2CL1
|
PINK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24999239
32088314
|
CASP1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9435230
9027312
|
B2L14
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
11054413
|
RTN4
|
RTN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
MOAP1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11060313
16713569
|
PRKN2
|
BECN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24386307
29330382
24879156
|
CFLAR
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10197438
16189514
9326610
|
B2CL1
|
DNM1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23792689
18250306
|
PP1A
|
APAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
17274640
|
DNM1L
|
PINK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
MCL1
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
17525735
5219960
|
CASP9
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9539746
16189514
25241761
|
MOAP1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11060313
16189514
16713569
|
RAF1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8929532
25241761
|
NALP1
|
CASP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18511561
17418785
|
B2CL1
|
PRKN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24999239
32088314
28038320
|
B2CL1
|
CYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9192670
16189514
25241761
16713569
|
NALP1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19223583
17418785
|
RAD9A
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18794804
10620799
|
B2CL1
|
RAD9A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10620799
16189514
|
PRKN2
|
DNM1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
30629163
21292769
|
RTN1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11126360
16189514
|
RTN4
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11126360
16189514
|
NALP1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19223583
17418785
|
BCL2
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
BAX
|
VDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
RTN4
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11126360
17191123
|
IKZF3
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16189514
11714801
|
BNIP3
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16189514
10625696
|
SPNS1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12815463
16189514
|
BNIPL
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9973195
12901880
|
APAF
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9539746
9488720
12963020
|
APAF
|
NALP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17418785
11113115
|
BBC3
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BCL2
|
FKBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BAD
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
BBC3
|
MCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
BNIP3
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10381623
7954800
23504944
10625696
|
BNI3L
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10467396
9973195
|
MCL1
|
BECN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17446862
21139567
22219388
|
MCL1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10837489
15077116
7937747
|
B2CL1
|
MTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
26593251
20080789
|
CFLAR
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
16537561
10837247
21988832
|
DYL1
|
BMF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14561217
32296183
31505170
|
PSN2
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
10446169
|
BCL2
|
BIK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
BAK
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
15901672
16439990
17289999
33961781
21712378
11571294
|
VDAC1
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9843949
16189514
15637055
28760928
12767928
|
BNIPL
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9973195
12901880
|
HRK
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9130713
10075695
15694340
|
BAP31
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9334338
31206022
|
FKBP8
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15733859
16189514
12510191
|
BNIP3
|
BNI3L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
10381623
16189514
25416956
30217970
33961781
26186194
21516116
24981860
27107012
19060904
|
CLUS
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21527247
21567405
|
B2CL1
|
BAP31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9334338
12594175
|
B2CL1
|
ASPP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21900206
18719108
|
APAF
|
CYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9267021
16713569
16979168
12147322
10206961
|
BAD
|
MCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
B2L11
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23235460
23374347
21199865
17289999
19427863
26186194
17525735
18948948
|
BAX
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
15574335
20956295
23374347
17289999
|
BBC3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15574335
|
FKBP8
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15905180
15733859
17942410
12510191
17379601
33961781
15990872
|
RAF1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8929532
8910675
12488548
9194558
15849194
|
P53
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21624955
30683842
21597459
32064756
19521340
12667443
9194558
16443602
23316052
|
BECN1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22498477
21971985
20889974
20010695
23504944
23564079
23168911
25891078
29955058
23822101
32097085
23954414
19959994
28128446
22241963
16179260
23316280
31410188
18641390
29079782
29849149
28682313
27304906
20711182
25984893
22622204
19180116
20622903
33977871
23541952
24034250
22082873
21543763
19347031
31696776
9765397
16713569
24879154
24141421
17446862
24472739
24599950
28431397
20577262
19050071
32820146
21358617
21139567
23479509
|
BAK
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20836993
14980220
26004684
32064756
9463381
11728179
11206074
|
ASPP2
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18719108
16713569
8668206
|
APR
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10807576
15694340
21454712
|
SPNS1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12815463
|
BID
|
MCL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15694340
16697956
19074266
15637055
21613222
33961781
|
APR
|
MCL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22219388
16697956
15901672
26045051
15721256
19148187
32094511
21454712
21139584
27517746
15694340
22361683
21132008
23341456
20085765
21613222
33961781
29799788
32913203
|
MCL1
|
BAK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15901672
26045051
15637055
27818144
19148187
32296183
10579309
22516262
19968986
23680104
18040043
21132008
20836993
17097560
20023629
19483105
15077116
10837489
21613222
33961781
26186194
26004684
|
PINK1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20057503
|
PINK1
|
PRKN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20798600
22724072
26116755
20153330
26162776
25474007
32983119
27605430
24357652
27528605
33730565
19358826
19167501
23933751
19966284
19229105
29330382
25591737
23319602
17052189
23670163
19880420
28945249
|
ASPP2
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21513714
16713569
8875926
14985081
19246451
18275817
8016121
25502805
8668206
32828017
23606740
|
BAK
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
16713569
32064756
15077116
27818144
25408501
21712378
|
VDAC1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
10737788
10049775
15637055
20080789
12767928
10365962
|
HRK
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14596824
16697956
15694340
15031724
10075695
9130713
15721256
|
APR
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10807576
15694340
21454712
15721256
|
BAX
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
BCL2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
B2CL1
|
BMF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
32296183
25416956
15694340
16697956
16260615
26871637
15721256
|
MOAP1
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
11060313
16189514
16713569
|
SIVA
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
12011449
14739602
|
PP1A
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
17274640
10811615
|
BMF
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
17289999
16697956
11546872
|
PP1A
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
11390485
17274640
|
BECN1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
19180116
7014480
|
BCL2
|
BECN1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
8095158
21139567
|
MCL1
|
BIK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
15694340
16697956
21613222
|
PP1A
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
12115603
17274640
|
MCL1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11483855
10837489
15694340
10579309
|
BID
|
BAK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10950869
23782464
23604079
25408501
12624108
|
ASPP2
|
PP1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
21189257
32296183
16713569
22321011
27880917
29669786
23088536
21998301
33961781
26186194
24366813
15231748
28330616
|
MCL1
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
18981409
19968986
21458670
15077116
21199865
10837489
33961781
26186194
17525735
21566062
19148187
|
BAX
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
25241761
18981409
32064756
21199865
17289999
19427863
9824152
27684187
18547146
9194558
24814347
21671007
21458670
28202514
26496610
12853473
16151013
12137781
9388232
9742125
22072718
19074440
11283018
21567405
15131699
9111042
14963330
9153240
9027312
21852238
33961781
28760928
26186194
25115399
17525735
29749471
|
BBC3
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15694340
16697956
17177603
15574335
19074266
27684187
28202514
14681455
33961781
22516262
16151013
15721256
|
B2CL1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
14980220
11583631
12137781
7937747
33961781
26186194
18835031
|
BIK
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8816500
32296183
16697956
15694340
9525867
9463381
17289999
33961781
12853473
9488477
31387940
|
CASP9
|
APAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
27197231
9390557
9878060
19698783
28716524
15262985
11242052
19494828
16979168
9922454
9488720
9539746
20462491
10376594
11113115
21060833
21827945
9837928
27476169
20829884
10206961
|
BIK
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11342619
16189514
16697956
15694340
32296183
9525867
9027312
12853473
26871637
27107012
15721256
|
BECN1
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
18628207
22219388
19049976
22498477
9765397
16713569
24141421
17446862
19713971
19180116
18641390
20577262
33961781
33931087
24443581
|
B2CL1
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
21900206
16189514
14963330
16713569
30683842
32064756
16151013
26556313
20837658
24474649
25115399
24814347
12667443
|
BAK
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
15901672
32064756
10085290
11175750
14596824
32296183
31467278
15292519
23055042
22516262
26264872
12137781
23680104
19060904
20836993
9362454
34098062
17446862
29997244
9027312
32814053
33961781
|
B2L11
|
DYL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
14561217
15193260
12591950
33961781
26186194
10198631
18420585
|
BID
|
MCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
BAX
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
7834748
9388232
17446862
9463381
20603619
10611223
14681455
11483855
33961781
19168699
15990872
9305851
15849194
|
BAD
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
16189514
16697956
25416956
25241761
31980649
21988832
10620799
11494146
10611223
14681455
9824152
19667065
27684187
11206074
15721256
32296183
31467278
20837658
26871637
19427857
9389483
12115603
15694340
26264872
11583631
7834748
9388232
12137781
11077446
11483855
18628207
15131699
20603619
29997244
15705582
32814053
33961781
9305851
26186194
|
BAX
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21778226
18981409
15899854
32064756
10620799
21199865
17289999
9194558
8358790
21671007
16642033
21458670
22262057
9388232
10716992
20865015
14980220
9111042
24141421
17097560
15231068
9463381
33961781
17525735
29749471
23479509
26004684
|
BBC3
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
15694340
16697956
14681455
17289999
33961781
11463392
26431330
|
B2L11
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
16697956
15899854
21199865
14681455
17289999
9430630
10198631
9731710
19805519
21671007
17074758
17692808
15694340
20836993
17097560
9463381
23845444
33961781
26186194
26004684
|
BID
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
19074266
11583631
9727491
9463381
15520201
14681455
17289999
18835031
12624108
|
B2CL1
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16189514
15694340
16697956
14963330
15574335
25241761
14681455
17289999
33961781
19074440
24814347
15721256
|
MCL1
|
B2L11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
20074640
16697956
26045051
21199865
26859456
9731710
15721256
19148187
16213503
20159608
22516262
19150432
15694340
23245996
21507240
21132008
20836993
17097560
15989957
27013495
20085765
19622586
10837489
21613222
33961781
26186194
17525735
19483105
|
B2L11
|
B2CL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
16697956
21199865
14681455
17289999
19427863
9430630
10198631
9731710
15721256
14596824
32296183
21671007
11859372
22516262
15694340
23245996
20836993
27013495
16260615
33961781
26186194
17525735
|
BCL2
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
BCL2
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
RAF1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11532940
12107820
12566895
14764585
15516985
19289794
19565474
24027568
8929532
9069260
|
RAF1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
11983683
12444011
10880354
19030972
19667065
22096607
15849194
16931767
17535812
16103085
9381178
23162742
12107820
18402774
12767520
10826997
8929532
8929531
12175651
25241761
19565474
10949026
19165420
9069260
21540285
17242355
23397142
19289794
|
MCL1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11571294
10579309
11483855
10837489
|
BAD
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
9305851
17145710
11483855
16697956
9463381
15694340
15849194
20603619
15990872
11583631
8929531
7834748
9388232
17446862
19168699
|
BCL2
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BAX
|
MCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
20709625
21641962
22039431
23064052
23377657
23430059
23850759
26587781
7644501
8358790
|
BCL2
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BAX
|
MCL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
20709625
21641962
22039431
23064052
23377657
23430059
23850759
26587781
7644501
8358790
|
BAX
|
MCL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
20709625
21641962
22039431
23064052
23377657
23430059
23850759
26587781
7644501
8358790
|
BID
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20956295
17289999
25241761
19968986
15574335
10629050
19062087
10949027
12242151
23374347
14730312
17520191
8918887
|
MCL1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
21458670
18981409
26186194
14766748
17289999
19968986
15077116
19062087
21199865
17525735
10837489
14730312
19148187
21566062
15713684
|
BCL2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
22705850
18981409
9463381
21458670
17097560
17525735
8358790
10620799
26004684
29749471
9388232
21199865
17525161
22262057
21778226
15486085
17289999
9111042
12419244
9194558
15231068
10716992
8183370
14980220
9115213
21671007
16642033
23479509
10677502
|
BAX
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
16189514
10365962
9843949
12767928
|
MCL1
|
BBC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
11463391
11463392
23430059
23850759
|
BCL2
|
BBC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BBC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11463391
11463392
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
MCL1
|
BBC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
11463391
11463392
23430059
23850759
|
BBC3
|
MCL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
|
BBC3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
16697956
15694340
11463392
|
BCL2
|
HRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9130713
|
BCL2
|
BMF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11546872
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
HRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
9130713
|
BCL2
|
BMF
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11546872
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
BECN1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
RAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11463391
11463392
11532940
11704864
12566895
12667443
14764585
15516985
17446862
19289794
19565474
22039431
23064052
23377657
23430059
23850759
24027568
8929532
9069260
9872359
|
BCL2
|
MCL1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
8.0
|
1.0
|
ACSN
|
11704864
17446862
22039431
23064052
23377657
23430059
23850759
8929532
|
HRK
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10075695
9130713
|
FKBP8
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10409669
15990872
15733859
17942410
12510191
17379601
20139069
|
BMF
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16697956
11546872
|
BNIP3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
23504944
10625696
10381623
19136941
7954800
|
RAD9A
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10620799
18794804
|
BCL2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
18835031
17145710
9463381
16697956
17289999
19074266
12624108
11583631
9727491
15520201
8918887
|
BCL2
|
BIK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
17145710
22705850
9463381
16697956
17289999
9488477
9525867
12853473
8816500
9305912
32296183
|
BCL2
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
72.0
|
1.0
|
Omnipath
|
23504944
17643073
23168911
21971985
19273585
16713569
19050071
16179260
23316280
22205736
23115300
18641390
28128446
17446862
23954414
22241963
23541952
29955058
25891078
29849149
24034250
24599950
9765397
25984893
21358617
18570871
16799551
19180116
20889974
20622903
23564079
19959994
20711182
23479509
19347031
20010695
21543763
22622204
24472739
17438366
|
CASP1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11085743
9727491
|
BMF
|
MCL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16697956
11546872
|
MCL1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
21353614
17446862
21139567
|
FKBP8
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24205284
17991864
|