Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
CHK1 MDM4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16511572 16163388
CHK1 HS90A â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 22939624 21566061 16330544
CUL1 HS90A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 21145461
RGAP1 CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARH CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
I13R2 CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SNX11 CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
NEK9 CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20562859 29262732
CATE CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ERC6L CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NAT9 CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PA2GX CHK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TCAL1 CHK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DRB5 CHK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ACHA9 CHK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
B2L14 CHK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRKDC BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10608806 25223785
CHK1 CUL1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17290223 19808933 34237211 30428154 23109433 16137618
CSK21 BRCA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10403822 16713569
CHK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11836499 17380128 28430840
BRCA1 CLSPN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15096610 22863316
CHK1 RAD51 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15665856 22665067
PRKDC CHK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10608806 12756247
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PRKDC P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11551930 10747897 25362358 9679063 11709713 9765199 10601022 11883897 19918261 12756247 10713094 11751391 8940078 10951572 10673501 10608806 9744860 10470151 16713569 9363941
CHK1 CSK21 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15225637 12902976
ATR CHK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32357935 21566061 15775976 11390642 11252893 19330022 10608806 23696651 17686975
CSK21 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15358769 25241761 23443559 11709713 10951572 11883897 10747897 12628923 10348343 12393879 24725084 22975381 10884347
ATR BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11114888 11278964 23901102 29656893 16713569 11016625 10608806 17478428
ATR P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16293623 15159397 11551930 11709713 9765199 10951572 15775976 10747897 11883897 10673501 20798688 15082766 10608806 10435622 11459832
P53 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14710355 16713569 21742769 15571721 26140185 9926942 9582019 14636569 14978302 16677609 18501503 9482880 19509300 16969499 31073355
RAD51 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 31009828 11498787 16713569 19766185 25659039 19369211 25499220 9774970 28319063 17302439 9008167 14636569 28976962 24085845 34408138 29656893
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
MDM4 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 29023092 30672125 31152661 17110929 19521340 10075736 30832340 22807444 12874296 25609649 11528400 24445145 17080083 18677113 20705607 27249653 9226370 17301054 18485870 26148237 27114532 16024788 22374672 24127580 18316739 26876197 29523541 21088494 23028042 24667498 30045945 20515689 25464845 22745160 19432880 21925390 28205554 20174603 21965653 25961923 21075307 22266850 8895579 28487147 32511789 10608892 30598450 25825738 19305137 19255450 11223036 15604276 16713569 28628118 16227609 10827196 12393902 20724842 24659749 12370303 23671280 17875722 33961781 31462704 26186194 23946421 31066983 19075013 15916963 19153082
P53 RAD51 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8617246 16713569 16983346 26140185 12606585 11948396 16600179 14636569 9380510 12750285 11002423 15064730
CLSPN CHK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12766152 16963448 16123041 23109433
CHK1 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11551930 9765199 11709713 11896572 15364958 16713569 10673501 12756247 16511572
P53 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32097779 16189514 15358769 16713569 21268072 23443559 31152661 11297531 21460846 15004035 22939624 30911017 11507088 11707401 15001357 10557093 12427754 32807901
CSK21 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 2492519 22113938 22824801 7794926 19740745 16335536
CHK1 MPIP3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10557092 11333986 16705183 9278512 32357935 11551930 11016625 16330544 11836499 11390642 17035231 28430840 12660173 9278511 10681541 19330022 29735693 15705874
CHK1 MPIP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9278511 12399544 12759351 18480045 12963847 17292828 27432908 12676583
ATR CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
ATR CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18309293 24500207 19473886 12766152 18077418
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723