Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
CHK1 MDM4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16163388 16511572
CHK1 HS90A â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21566061 22939624 16330544
SNX11 CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CUL1 HS90A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939624 21145461
RGAP1 CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ERC6L CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NAT9 CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PA2GX CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
I13R2 CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEK9 CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29262732 20562859
ARH CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CATE CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
B2L14 CHK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ACHA9 CHK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DRB5 CHK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TCAL1 CHK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CHK1 CUL1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19808933 17290223 34237211 23109433 30428154 16137618
PRKDC BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25223785 10608806
CSK21 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16713569 10403822
CHK1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17380128 11836499 28430840
BRCA1 CLSPN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15096610 22863316 16713569
CHK1 RAD51 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15665856 22665067
PRKDC CHK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10608806 12756247
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PRKDC P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9765199 19918261 10470151 10713094 9363941 9744860 10601022 11551930 11709713 10951572 16713569 8940078 25362358 11751391 12756247 10673501 10747897 9679063 11883897 10608806
CHK1 CSK21 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12902976 15225637
CSK21 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15358769 10884347 10747897 12628923 10348343 24725084 25241761 11883897 22975381 11709713 10951572 12393879 23443559
ATR CHK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21566061 15775976 11390642 10608806 32357935 17686975 11252893 23696651 19330022
CLSPN CHK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16123041 23109433 12766152 16963448
ATR P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20798688 10435622 10673501 16293623 10747897 15775976 9765199 11883897 11551930 15159397 10608806 11709713 10951572 11459832 15082766
CHK1 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10673501 16511572 11896572 9765199 11551930 15364958 11709713 16713569 12756247
MDM4 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 31462704 10827196 19255450 22745160 23671280 31066983 10075736 10629057 11528400 15604276 24445145 19521340 19075013 12370303 30598450 21965653 19432880 16024788 31152661 21088494 22807444 17301054 30832340 17875722 16713569 20724842 28628118 16227609 30672125 25464845 25825738 22266850 24659749 20515689 21075307 20174603 18316739 17110929 20705607 10608892 24127580 29023092 26876197 24667498 9226370 18677113 27114532 28514442 22374672 17080083 8895579 12393902 29523541 32511789 30045945 19305137 23028042 18485870 11223036 26148237 25609649 19153082 26186194 21925390 28205554 23946421 28487147 15916963 12874296 25961923 27249653
P53 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15358769 31152661 30911017 32097779 15004035 11707401 10557093 32807901 11507088 11297531 12427754 16713569 21268072 21460846 22939624 15001357 16189514 23443559
P53 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14978302 9582019 14710355 21742769 18501503 9482880 14636569 9926942 16677609 26140185 19509300 15571721 16713569 16969499 31073355
P53 RAD51 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16983346 15064730 8617246 11948396 14636569 16600179 12606585 26140185 16713569 11002423 9380510 12750285
CSK21 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19740745 2492519 22113938 16335536 7794926 22824801
CHK1 MPIP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9278511 12399544 12676583 17292828 12759351 27432908 12963847 18480045
CHK1 MPIP3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9278511 12660173 16330544 9278512 15705874 11390642 11836499 11016625 28430840 11551930 10557092 10681541 16705183 32357935 29735693 19330022 11333986 17035231
RAD51 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11498787 31270457 19369211 14636569 24085845 29656893 28319063 25659039 34408138 31009828 9774970 16713569 25499220 19766185 17302439 9008167 28976962
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
ATR CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18309293 24500207 19473886 12766152 18077418
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368