BAX
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11709054
|
ARAF
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18039929
|
ARAF
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18039929
|
CHEK2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19001859
12364621
|
CHEK2
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16651405
10724175
|
BCL2L11
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
BCL2L11
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
AHR
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11455387
11479581
|
BAX
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0912742107
20080742
|
BCL2L11
|
BAX
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
7034061
19427863
|
PRKACA
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21151042
8142029
|
CDK1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
22071694
|
EP300
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23353771
23285190
|
CDC25A
|
CHEK2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
11298456
5213933
|
MAPK14
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19289404
|
CDC25A
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15672448
|
MAPK1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17205132
|
AHR
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17070097
15111621
|
ESR1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24559156
10851069
|
CHEK2
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32187724
|
CLOCK
|
CACNB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16006522
14563928
|
CLOCK
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20930143
19922678
|
MAPK1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
CLTC
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
EP300
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
EP300
|
BIRC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20660371
19102934
|
EP300
|
CDKN2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22000024
19419955
|
EP300
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828133
24058639
|
MAPK3
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24530506
|
AP2A1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
CLTA
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
AP2A2
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
MAPK1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
MAPK1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10608864
10818153
|
MAPK1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
ESR1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23250869
22430216
|
MAPK1
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8941362
|
ESR1
|
MAPK12
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16885352
22399296
|
MAPK11
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23602568
21900206
|
MAPK3
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
CALM3
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
CALM3
|
CAMK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8340352
20668654
|
CALM2
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
CALM2
|
CAMK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8340352
20668654
|
CCR4
|
CACNA1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
COX7C
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX7C
|
COX4I2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
ESR1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12603855
26790618
|
HSPA5
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
AP2B1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
ESR1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
CREBBP
|
POU1F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10931853
9751061
|
BIRC3
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23070005
18485876
|
SOX9
|
COL9A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12399468
17264118
|
CREB3
|
ACSL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
CREB3
|
SLC19A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
CREM
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18721873
12533437
|
PRKACA
|
CACNA1D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19074150
|
MITF
|
ATP6V1B2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19321441
23379601
|
ESR1
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11060032
21610700
|
CCND3
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16609025
|
MITF
|
BRAF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23831555
16001072
|
CAMK2A
|
ATP1A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CAMK2A
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9768837
8798667
|
POU1F1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18653622
9702189
|
ESR1
|
BDNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16262660
7479947
|
ARHGDIB
|
CASP7
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
ANAPC4
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC23
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC2
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC2
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
ANAPC4
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CDC23
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10500174
|
CD3E
|
CD3G
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CREB3L1
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15572842
15665855
|
HSPA5
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11943137
|
ATP6V1G2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14667819
5216829
|
CAMK2D
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20668654
1000426
|
CAMK4
|
CREM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8523736
7799965
|
ATM
|
CHEK2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
10973490
|
ATF4
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
ESR1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
1204073
5215931
11244506
|
CDK1
|
CCNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
7799941
1628647
14681455
8565853
16009130
|
GSK3B
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
25241761
14536078
8861947
|
ATP6V0A2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
809.0
|
0.81
|
STRING
|
36370105
|
ATP2B4
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
C8B
|
C9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
COX4I1
|
COX8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
COX7C
|
COX8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
APC
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
20936779
|
BRCA1
|
ASH2L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
26831064
|
BAD
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19427863
17274640
|
ARRB2
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32962859
17620599
|
ATP6V0A1
|
ATP6V0E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
CNGA3
|
ADCY3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ATM
|
CHEK1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
20068082
|
CDK1
|
CDC25A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
12411508
|
CDC25A
|
CDK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
10454565
|
ATP6V0B
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
CDC20
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
CCND3
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
26496610
|
CCNE1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9053846
9891079
1388288
|
CDK1
|
BIRC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11861764
17681274
|
CDC20
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
16319895
|
CCR5
|
CCL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9334377
10477718
10498628
8663314
23597562
12427015
9468473
|
CDK5
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23455922
33961781
23602568
|
ATP6AP1
|
ATP6V0A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
CCND3
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ARRB2
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
BRAF
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
AP2B1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
CALM3
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CALM2
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
CDK1
|
CDC20
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
10799291
26912231
|
COX4I1
|
COX6A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
ACTN4
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21078666
19805454
25604459
|
ESR1
|
ASH2L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21502505
16603732
31527615
|
EP300
|
SOX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15623506
35140242
12732631
19828133
|
C8A
|
C8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
ATP6V0A2
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
APC
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17145773
21311754
|
BRCA1
|
CCNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
9244350
10373534
|
ATF4
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
14630807
17872950
10350644
12471036
16219772
|
BIRC5
|
BECN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26148234
20638385
|
CCR4
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8573157
12270118
|
ATP6AP1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
CCNA1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
COX4I1
|
COX6A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
BECN1
|
AMBRA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
23974797
|
CDC26
|
CDC20
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26811472
23443559
20360068
25306918
25723520
|
AP2A1
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
33961781
26344197
|
CDC23
|
CDC26
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26496610
20360068
|
BRCA1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CACNA1B
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CACNA1B
|
CALM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CCND2
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
ARAF
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
AHR
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ATM
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CHUK
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
AP2B1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
CLTB
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CREBBP
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CLTB
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CAMK2D
|
CAMK2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
AHR
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10999956
17392787
21988832
|
AP2A2
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12086608
16189514
33961781
34079125
26344197
|
CASP7
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16339151
30948266
9384571
|
COX4I1
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
COX6A1
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
ANAPC11
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
MAPK1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
AP2A1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
C1QB
|
C1QA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14681455
21054788
12960167
|
CDC20
|
CDC23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18997788
27114510
26811472
23443559
24464857
20360068
25306918
26496610
28404789
|
BIRC5
|
CASP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11024045
16189514
11170436
9850056
|
AP2S1
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
12086608
16189514
33961781
34079125
26344197
|
CDK5
|
CCND3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
33961781
26186194
23602568
23455922
|
CASP7
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
16339151
9384571
11084335
33961781
15580265
19258326
|
AHR
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15837795
19460354
12612060
27420286
17392787
10620335
9611253
|
CDC26
|
CDC27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20360068
12956947
16364912
25723520
33961781
32152539
32076268
14657031
10922056
21043528
|
ATM
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
AMBRA1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
MAPK14
|
RPS6KA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CDC25A
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
BRAF
|
ARAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
25241761
31980649
28628118
17979178
20130576
34017080
33961781
28205554
|
ATM
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
29656893
10783165
11016625
10866324
10550055
15713674
18344987
10608806
17478428
|
MAPK3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19777442
10597268
12566304
|
MAPK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8929531
10597268
12566304
|
BAX
|
BCL2L11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
MAPK14
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15486195
17570479
16818494
|
ESR1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
1244506
11782371
15674350
29367421
27977889
17392432
16860316
10334989
16260778
11244506
16061635
12400015
17505062
20060929
25499220
16713569
31527615
11493692
|
EP300
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21102443
19887647
10655477
11782371
16713569
21212407
22787115
|
CREB3
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
MITF
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19067971
15623583
1999537
|
EP300
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
11782371
12738788
25728767
11867769
12479814
23065768
15308690
20388208
14761960
22227247
8799122
20348541
23403292
12714702
11581164
16713569
19838210
18765668
16645043
30418174
12574227
|
BRAF
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16508002
14654779
19933846
|
MAPK1
|
ATP1A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15069082
14976217
|
MAPK11
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK14
|
MITF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11792706
|
MAPK14
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15649893
|
BRAF
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
BRAF
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16508002
14654779
19933846
|
MAPK3
|
MITF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12819038
10841026
|
ESR1
|
C3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10418989
8961270
17478088
|
CCR5
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11449371
10477718
10488147
9334377
8663314
14637022
9207005
11116158
9289016
|
CDC20
|
CDC27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
24100295
20081372
24464857
20360068
16479161
24781523
25246557
17443180
18471975
18997788
18059335
23239745
23643811
25161877
20054826
14561775
22193957
25750436
20212161
21926987
22280307
21937719
19098431
25673878
26811472
27114510
29700288
25306918
12956947
9811605
23754430
18794143
9628895
17443186
32076268
21525009
22100920
23160376
24811168
20951947
9637688
23443559
9736712
22014574
9734353
18722180
30341343
25156254
17609108
28404789
29432156
26960431
21335556
12196507
32152539
23979597
21454660
17360335
23007861
|
AP2A2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20947020
17199046
12958364
|
ARRB2
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21118812
17620599
12070169
10097102
|
ARRB2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20947020
17199046
12958364
|
CCND2
|
CDK5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32707033
16189514
9422379
25416956
32296183
33961781
26186194
23602568
27107012
26871637
23455922
|
GSK3B
|
CDK5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17607942
15676027
15652488
|
ESR1
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11457657
10949931
17068199
|
PRKACA
|
CACNA1H
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19131331
|
GSK3B
|
ACTL6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
CDC27
|
CDC23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20360068
22792066
26496610
22193957
17942546
22280307
21043528
27114510
16648845
32934012
12956947
32076268
20686030
22939629
10922056
16364912
27173435
32152539
14657031
26344197
|
CDC23
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
10500174
|
ANAPC4
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25383541
10500174
|
CDC27
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25383541
10500174
|
CDC27
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
10500174
|
AKT1S1
|
RPS6KA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
C8A
|
C9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
C8A
|
C9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10346902
3624872
4063341
|
CREM
|
CAMK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9238860
7493991
7799965
|
BRCA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
CLTA
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
APC
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
CCNE1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V0A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
CANX
|
GANAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
CDC20
|
CCNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
19477924
10679238
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
ATP6V0A1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
ATP2B4
|
CALM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CD3E
|
CD3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ATP6V0B
|
ATP6V0C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATP6V0C
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
BAX
|
BCL2L11
|
â—¼ PROXIMITY
|
✅
|
|
0.94
|
0.94
|
mint
|
7034061
19427863
|
CD3G
|
CD3E
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
20890284
9582308
2138083
|
ATP6V0C
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C2
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CNGA1
|
CNGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CACNA2D1
|
CACNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CALM3
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
CALM2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
COX6B1
|
COX7C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
CHEK1
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
ANAPC13
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
ANAPC11
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
COX4I1
|
COX6B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
CAMK2A
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
AP2S1
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
31353312
16189514
7593184
33961781
26344197
|
CAMK2B
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
CDC25A
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
COX6A1
|
COX6B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
C1QA
|
C1QB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
APC
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11166179
29045831
21118991
8638126
11251183
23602568
29568061
|
AP2S1
|
AP2A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
33961781
26344197
|
CAMK2A
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
ACTR10
|
ACTR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
AP2A1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CCL5
|
CCR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CDC20
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CDC23
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ARRB1
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ANAPC13
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
ANAPC4
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ANAPC13
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
AP2A2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ANAPC13
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ANAPC4
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
ATP6V1B2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CLTA
|
CLTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
ANAPC2
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
AP2B1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CDC20
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
AP2A2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDC23
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDC26
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC4
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
ANAPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
CDC26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC2
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ANAPC11
|
ANAPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ACHE
|
APAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11864614
12522243
14622304
15087373
17377525
18439902
22514517
|
ACHE
|
APAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15087373
14622304
12522243
17377525
11864614
18439902
|
CHUK
|
APC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
12799363
23430059
7542250
8666229
|
PRKACA
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11050185
11166179
15649893
11689703
|
GSK3B
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
16944320
11166179
16799642
11967263
14663202
8524413
12554650
8638126
17910481
15327768
10581160
11487578
17318175
15465828
10228155
15020233
10421629
10698523
9832503
|
BRCA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
CDK5
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
12556884
16332722
16858402
17303408
19151707
20724832
21727086
21922195
23589330
23850759
|
ATM
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
CHEK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
CHEK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
CDK5
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17303408
23589330
16858402
19151707
27470939
16332722
12556884
21600237
21922195
|
ATM
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20471956
15494392
15140942
29590107
26170237
21108945
15838517
27220480
|
ATM
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
176.0
|
1.0
|
Omnipath
|
26683224
17303408
28852018
10713094
20080130
27545311
9488723
15342622
23941746
26485758
28937603
15279786
24882580
10744722
15125777
25746763
18583988
28051860
17570479
16531125
21329876
23892398
19607708
16940182
26643553
20396397
28259974
25361978
17660363
15459660
19375317
25247188
16311512
23118481
20498628
22030216
25613496
22420423
9407949
17918214
12493754
20859824
26158765
15700044
27558808
11901158
27602502
20637859
16163361
20599567
23638118
16481012
12242661
23847781
12024051
15140942
11728459
12454775
16936775
25450480
28950914
26295265
20160490
22319212
24349411
18006705
20723763
18678890
12805407
20860841
23386996
24050180
11668173
27271602
29304495
12447382
24798733
9889122
23347679
18794134
21147465
21421565
26516160
17715138
21376743
19440053
12773400
10973490
17174984
26442630
15694385
11877377
29022904
18809224
11850621
18787700
12718885
19481982
22743550
20372057
15212693
16085488
19101576
29555944
25954303
24473398
18087292
16794575
24492479
24244353
19793801
25404613
21102523
29156743
23253087
16997395
7575488
25808488
20647331
18584027
21851590
21315088
23705030
15629715
29741650
21772273
11025670
18590585
26610585
15964794
29434792
20068082
23006513
19881958
19230643
12607003
24769180
25249630
15024084
19772495
25714019
18603484
25173936
23666059
19473886
27568553
22808196
|
ATM
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
69.0
|
1.0
|
Omnipath
|
29774099
20976184
26683224
25663895
12676583
17303408
14657349
29167438
27545311
10859164
19056039
15485915
28808226
12588868
16163361
15650047
12676962
17570479
14988723
14681223
26516160
10608806
26069190
29741650
12676925
23847781
17118344
11252893
20376879
15964794
15149599
18691976
19059218
20068082
15707391
12607003
25450480
17525332
11553781
19646247
15870257
15459660
20798862
19716789
11877377
12660173
11390642
15674326
16782033
28396830
28228262
12446774
15533933
15212693
29555944
|
ATM
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
26927092
17303408
15159397
24746700
12024016
10866324
30197789
12919958
11114888
26745677
26383678
34301763
12427729
11313470
16163361
28035057
20068231
25939603
26320175
17570479
19683496
22743550
10608806
23802008
23847781
21203981
15964794
12183412
12607003
17525332
19996295
15459660
11278964
19651622
21706030
11877377
20952512
10373534
19622773
10550055
27170701
15212693
23704879
|
CDK1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12049737
14551205
15279786
17303408
17660363
18414028
18590585
21725609
7575488
|
PRKACB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15280015
10611223
12954615
9346240
10949026
11493700
10230394
10558990
8929531
9381178
17270021
10837486
|
PRKACG
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
15280015
10611223
10230396
12954615
9346240
10949026
11493700
10230394
10558990
8929531
9381178
17270021
10837486
|
CDK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
18071308
16166315
24677263
12965220
15907327
26287183
21858202
25618528
12049737
16009721
19124971
16403219
17498878
|
PRKACA
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
11983683
10880354
20166139
9346240
11493700
9381178
18794113
12931191
15280015
10230394
10558990
8929531
18669648
10837473
10837486
10611223
12954615
10949026
10851172
15123689
18707149
16403219
17270021
|
RPS6KA5
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
11983683
15280015
10880354
10611223
12954615
9346240
11493700
10230394
10558990
8929531
9381178
12213813
17663748
17270021
10837486
|
BCL2L11
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10198631
12419244
15486085
15724238
23430059
23850759
9430630
|
BCL2L11
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
22492984
26186194
17289999
12419244
11301022
12198137
17525735
21199865
18948948
23235460
11997495
15486085
12242151
23374347
19427863
15721256
|
GSK3B
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
29379583
27762303
15525785
20976235
26287183
17911107
16709574
|
MAPK3
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
15486195
25915848
17604722
14555991
28474232
19150432
18174237
12646560
12818176
15486085
15212693
14681225
|
MAPK1
|
BCL2L11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
15486195
17604722
14555991
28474232
19150432
12646560
16282323
12818176
17570479
15486085
15212693
|
CHEK2
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11438669
15459660
15810020
15867354
17296736
17464182
17568790
18048416
18566216
18756267
18931676
18971944
19686080
19788416
20019063
20126263
|
BRCA1
|
CHEK1
|
â—¼ REGULATES
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10367887
10779360
10962562
11877377
12024039
12170778
12496474
12771027
15242590
15459660
15485915
16818604
19004803
19357644
19686080
19788416
19793801
20029420
21060331
21337561
9346961
9892649
|
CHEK2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
18566216
15810020
24492479
20860841
16713569
26383678
10724175
12049740
24986639
23388117
14701743
30327455
33397362
22921572
18804494
24348208
20364141
22941656
15459660
17464182
20952512
24069304
15485917
22193408
12111733
27170701
|
CDK1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9244350
21706030
10550055
17570479
19683496
16713569
26745677
32193285
26719576
|
BRCA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11244506
12400015
15674350
10334989
16713569
11493692
|
CHEK2
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11438669
15459660
15810020
15867354
17296736
17464182
17568790
18048416
18566216
18756267
18931676
18971944
19686080
19788416
20019063
20126263
|
CDK1
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
1075565
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17568790
17596790
17660363
18073536
18414028
18543256
18590585
18786381
18995830
19652693
19686080
7575488
9892021
|
CHEK1
|
CDC25A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
15459660
15798197
17102137
17116885
17296725
17384638
17568790
17582221
18677104
19793801
20126263
|
CHEK2
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
52.0
|
1.0
|
Omnipath
|
18566216
12676583
15810020
18285803
12759351
14681206
20860841
16682204
9836640
10724175
29725502
23855452
20126263
18480045
11298456
20587702
15459660
20514219
22263797
27038604
17464182
14559997
12399544
17568790
24882577
19101576
|
CHEK1
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
75.0
|
1.0
|
Omnipath
|
12676583
22040655
29435105
12759351
14681206
18677104
20860841
15798197
19793801
22655267
12963847
16682204
14752276
16647857
15736430
29725502
17116885
17582221
20126263
16697662
18167338
19075565
9278511
18480045
17384638
21148633
21252624
27493659
12110582
17030123
23335075
20068082
11298456
27908669
27213455
25936524
15459660
28150240
20798862
22263797
27038604
17296725
14559997
12399544
17102137
17568790
16488126
|
GSK3B
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
27038604
20348946
29725502
22655267
19230643
17570479
18167338
18480045
28680535
|
CDK1
|
CDC25A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17303408
18073536
1075565
19413330
15279786
7575488
17172867
17570479
12411508
18167338
27580187
18927152
19652693
18590585
12124778
18786381
17660363
21379580
15917306
22263797
27038604
17568790
|
CDC25A
|
CCNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
18073536
10926775
1075565
17568790
16189514
18786381
17660363
15279786
|
CDC25A
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
8617791
17303408
18073536
1075565
17568790
18786381
17660363
15279786
|
CDK1
|
CDC20
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17596790
17660363
18414028
18543256
18590585
18995830
19652693
19686080
7575488
9892021
|
CDK1
|
BIRC5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11069302
12124778
12792650
14551205
15279786
15917306
17303408
17466630
17660363
18414028
18590585
19016842
19081073
19586613
19652693
7575488
|
GSK3B
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9832503
17359287
|
CDK1
|
BIRC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
16565220
24281185
18676872
11149963
12529428
24478433
19287963
18936249
18949405
16170024
20068231
28536639
16189514
33710603
20462440
29371939
18691976
15894279
12517802
11861764
11069302
33211707
28392503
21765467
23433354
18931693
15735703
34034636
25468890
26918045
32373497
|
CDK1
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
15279786
15917306
|
CDK1
|
ANAPC11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
15279786
15917306
|
CDK1
|
CDC26
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
15279786
15917306
|
CDK1
|
CDC23
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17570479
17660363
14657031
15279786
15917306
|
CDK1
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
20798862
19837665
18691976
21765472
21907702
29092815
18983824
16629900
22686412
24242917
|
CDK1
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
16565220
17303408
29084198
33819340
12124778
17570479
17660363
14657031
15279786
15917306
|
CDK1
|
ANAPC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
14657031
15279786
15917306
|
EP300
|
CDKN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
32284348
19273602
32601262
10821856
28985506
33043019
31597407
|
CDKN2A
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
32284348
19273602
32601262
10821856
28985506
33043019
31597407
|
CHEK2
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26516160
24804719
26437226
29555944
|
CDK5
|
CLOCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24235147
|
MAPK1
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17623675
24530506
|
EP300
|
MITF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9660747
|
EP300
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17306568
17666529
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
MAPK14
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
11157753
22521293
17255949
11238443
11274345
12697810
|
MAPK13
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12975377
23602568
16424009
19058874
23397142
21707490
|
MAPK1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16039586
28646232
18451303
|
MAPK1
|
MITF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
21887372
10952390
16162175
29121864
9440696
10673502
12819038
20701798
27428965
16246839
|
MAPK1
|
RPS6KA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
20506250
15547943
18267068
15302935
12697810
11940578
12414794
17117922
23331499
21071413
23047924
20068231
16393692
9687510
17255949
15187187
19541618
19565474
17052211
15568999
19651622
14578350
11018520
15684425
11994045
11274345
|
MAPK1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
15655247
10949034
15528270
18372406
15461668
12118371
12466266
7495695
17615152
15059947
16076840
7491495
12093745
10409727
9528769
7838153
|
MAPK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
14654779
21478863
19541618
16508002
19710016
19933846
15664191
29335436
8621729
|
MAPK1
|
RPS6KA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15187187
19541618
19565474
20506250
18813292
17052211
15547943
16393692
17570479
9687510
17255949
11274345
12697810
|
MAPK1
|
ARRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19651622
19153083
18767875
17322306
15456867
10347142
20068231
19413330
9388255
|
MAPK12
|
RPS6KA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
11274345
|
MAPK12
|
RPS6KA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
11274345
|
MAPK14
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
26822034
17726008
21303975
18451303
|
MAPK14
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
23397142
11238443
11274345
12697810
|
MAPK14
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23216744
22431515
12138194
15879307
|
MAPK14
|
RPS6KA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
10806207
17145710
23602568
20506250
11035004
23331499
21614932
20068231
9792677
16393692
10922375
17570479
25852190
15187187
26186194
15140942
18691976
18813292
19651622
19436832
11157753
16964243
11274345
|
MAPK14
|
ARRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK14
|
RPS6KA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
20506250
15302935
17117922
23047924
21614932
20068231
10922375
16393692
9687510
15187187
20936779
26186194
19940164
15140942
18813292
15568999
19651622
19436832
14578350
11157753
15684425
11994045
11274345
|
MAPK14
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17486076
27843138
|
MAPK11
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK13
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK3
|
RPS6KA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15187187
17145710
23331499
19541618
19565474
20506250
17052211
15547943
9792677
16393692
17255949
11274345
12697810
|
MAPK3
|
RPS6KA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
20506250
15547943
15302935
12697810
12414794
17117922
20068231
16393692
19251839
17255949
15187187
19541618
19565474
18813292
17052211
15568999
19651622
14578350
11891214
11018520
15684425
11994045
11274345
|
MAPK3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10949034
18372406
15461668
9528769
12118371
14680484
17615152
15059947
16076840
7491495
12093745
15212693
15528270
7838153
|
MAPK3
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
14654779
21478863
19541618
21135229
16508002
19933846
15664191
8621729
|
MAPK3
|
ARRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
19651622
19153083
18767875
17322306
15456867
10347142
20068231
19413330
9388255
|
MAPK3
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16039586
28646232
|
ATF4
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11564156
9295363
25241761
|
CALM3
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
CALM2
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
CCL4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10498628
16298345
8663314
10477718
9468473
20219869
23597562
10699158
9334377
9790730
16467191
22633458
12427015
12964882
|
AMBRA1
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
21358617
22441670
23030059
23377657
23974797
|
AMBRA1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20562859
23974797
20711182
20417604
21358617
25438055
23954414
20921139
24587252
17589504
25499913
33562550
|
CCL5
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8573157
12270118
|
COX7C
|
COX4I1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX7C
|
COX4I1
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
CCL5
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
16298345
10488147
28381538
10699158
22633458
9289016
12213786
8663314
11449371
10318947
12964882
25923671
9207005
23480650
11116158
10477718
14637022
9334377
9790730
|
CDC20
|
CDC27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
BIRC5
|
CDC20
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12925766
14767480
15249581
16571674
17956729
|
CDC27
|
CDC20
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
25156254
12956947
9736712
17443186
22014574
9637688
24781523
16189514
14561775
12196507
|
CDC20
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
25156254
12956947
9736712
17443186
22014574
9637688
24781523
16189514
14561775
12196507
|
CDC20
|
ANAPC11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25241761
27509861
18997788
26387737
9734353
|
BIRC5
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9384571
11024045
9850056
16189514
11170436
|
CHUK
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
21674813
17145710
14597638
17434128
22435559
12789342
27220480
|
AP2A2
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
AP2A2
|
CLTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
CLTCL1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
CLTCL1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
CAMK4
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11970865
|
CREBBP
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9192902
18765668
16417649
11113179
8616895
11782371
14766010
17400812
|
ARHGDIB
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16714282
7512369
9113980
23434736
11306516
|
BIRC2
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16339151
9384571
16189514
11084335
|
AP2A1
|
CLTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
AP2A1
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
PRKACA
|
SOX9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
27929080
19470758
10805756
15889150
|
PRKACA
|
AKAP13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15383279
15229649
15324660
|
PRKACA
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22266331
9891036
15193262
|
PRKACA
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11510412
10931830
|
PRKACA
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
16543730
15845746
18691976
19836308
8524413
12054501
16039586
12147701
16522636
11035810
18669648
|
PRKACA
|
CACNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10567342
10441130
|
CAMK2A
|
CACNA1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16982421
9278528
|
GSK3B
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17486076
11152665
20537194
10385618
11124803
12969793
19757160
16732330
10486203
16039586
14536078
18167338
12459251
12615961
|
GSK3B
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
11152665
20537194
10385618
15252116
11124803
16331257
12969793
19757160
16732330
10486203
16039586
14536078
18167338
15326477
12459251
12615961
17092340
15212693
|
GSK3B
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
16944320
11967263
14663202
8524413
8861947
16039586
17570479
14536078
12615961
19561641
15465828
25241761
18691976
18319725
12459251
15020233
20537194
11124803
16131838
9832503
15364936
|
GSK3B
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10428798
10949034
17609434
15461668
9528769
12118371
15059947
16076840
17570479
7491495
12093745
8308015
15212693
15528270
7838153
|
MAPK11
|
RPS6KA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15187187
19436832
23331499
15140942
21071413
20506250
21614932
16393692
9687510
11274345
|
MAPK11
|
RPS6KA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
11274345
|
AHR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12612060
17392787
10620335
|
ANAPC2
|
CDC27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
10922056
10500174
|
CDC27
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
10922056
10500174
|
ANAPC2
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ANAPC11
|
ANAPC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12956947
24163370
11739784
10230407
|
ANAPC2
|
ANAPC11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12956947
24163370
11739784
10230407
|
ANAPC4
|
CDC23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ATF6B
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17522056
14973138
11256944
|
BIRC3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16339151
9384571
|
CAMK2D
|
CACNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20194790
|
C9
|
C8B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9038722
16999828
7691959
17505110
16079145
|
C9
|
C8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9038722
16999828
7691959
17505110
16079145
|
CAMK2G
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
9768837
8798667
|
MAPK13
|
RPS6KA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
11274345
|
MAPK13
|
RPS6KA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
20506250
21614932
16393692
11274345
|