Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
3C-like proteinase ATP6V1G1 â—¼   CLEAVAGE ✅ - 0.2 0.2 Signor
A2M ADAMTS12 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
A2M ADAMTS7 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
A2M CTSE â—¼   CLEAVAGE ✅ - 0.39 0.39 Signor
A2M MMP2 â—¼   CLEAVAGE ✅ - 0.64 0.64 Signor
A2M MMP9 â—¼   CLEAVAGE ✅ - 0.46 0.46 Signor
ABL1 PARK7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
ABL1 PARK7 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
ACAA1 TYSND1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ACAN ADAMTS4 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ACAN ADAMTS5 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ACAN ADAMTS5 â—¼   CLEAVAGE ✅ - 0.73 0.73 Signor
ACAN HTRA1 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
ACAN MMP19 â—¼   CLEAVAGE ✅ - 0.4 0.4 Signor
ACAN MMP20 â—¼   CLEAVAGE ✅ - 0.47 0.47 Signor
ACAN MMP3 â—¼   CLEAVAGE ✅ - 0.71 0.71 Signor
ACE AGT â—¼   CLEAVAGE ✅ + 0.74 0.74 Signor
ACE AGT â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome
ACE Angiotensin-2 â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
ACE2 AGT â—¼   CLEAVAGE ✅ + 0.73 0.73 Signor
ACE2 AGT â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
ACE2 ALB â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ACE2 APLN â—¼   CLEAVAGE ✅ + 0.38 0.38 Signor
ACE2 Angiotensin 1-7 â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
ACE2 Angiotensin-1 â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
ACE2 CSN2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ACE2 CTSL â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
ACE2 FURIN â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome
ACE2 TMPRSS2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
ACIN1 CASP3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ACOX1 TYSND1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ACOX1 TYSND1 â—¼   CLEAVAGE ✅ + 0.65 0.65 Signor
ADAM10 APP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
ADAM10 BTC â—¼   CLEAVAGE ✅ + 0.34 0.34 Signor
ADAM10 CD44 â—¼   CLEAVAGE ✅ + 0.32 0.32 Signor
ADAM10 CDH1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
ADAM10 DLL1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome
ADAM10 DLL4 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome
ADAM10 EGF â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM10 ERBB2 â—¼   CLEAVAGE ✅ + 0.31 0.31 Signor
ADAM10 JAG1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome
ADAM10 JAG2 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome
ADAM10 NOTCH1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome
ADAM10 NOTCH2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
ADAM10 NOTCH3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM12 EGF â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM15 CDH1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
ADAM17 APP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAM17 APP â—¼   CLEAVAGE ✅ + 0.52 0.52 Signor
ADAM17 AREG â—¼   CLEAVAGE ✅ + 0.4 0.4 Signor
ADAM17 BTC â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 CD163 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
ADAM17 EGF â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 ERBB4 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 EREG â—¼   CLEAVAGE ✅ + 0.52 0.52 Signor
ADAM17 EREG â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 FURIN â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome
ADAM17 GHR â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 GP1BA â—¼   CLEAVAGE ✅ - 0.27 0.27 Signor
ADAM17 HBEGF â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 MUC1 â—¼   CLEAVAGE ✅ - 0.28 0.28 Signor
ADAM17 NGFR â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
ADAM17 NOTCH1 â—¼   CLEAVAGE ✅ + 0.72 0.72 Signor
ADAM17 NRG1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 NRG4 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAM17 SHH â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
ADAM17 TGFA â—¼   CLEAVAGE ✅ + 0.49 0.49 Signor
ADAM17 TNF â—¼   CLEAVAGE ✅ + 0.68 0.68 Signor
ADAM17 TNF â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
ADAM30 CTSD â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAM9 FGFR2 â—¼   CLEAVAGE ✅ - 0.24 0.24 Signor
ADAM9 MMP14 â—¼   CLEAVAGE ✅ - 0.31 0.31 Signor
ADAMTS12 A2M â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAMTS12 COMP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAMTS12 COMP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAMTS13 VWF â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAMTS13 VWF â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAMTS4 ACAN â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAMTS5 ACAN â—¼   CLEAVAGE ✅ - 0.73 0.73 Signor
ADAMTS5 ACAN â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADAMTS5 TIMP3 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAMTS7 A2M â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADAMTS7 COMP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ADCYAP1 DPP4 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
ADCYAP1 FAP â—¼   CLEAVAGE ✅ 2.0 0.8 intact
ADCYAP1 FAP â—¼   CLEAVAGE ✅ 0.44 0.44 mint
ADD1 CASP3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
ADPRH H1-1 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
AFG3L2 PMPCB â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
AGPS TYSND1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
AGT ACE â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome
AGT ACE â—¼   CLEAVAGE ✅ + 0.74 0.74 Signor
AGT ACE2 â—¼   CLEAVAGE ✅ + 0.73 0.73 Signor
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
AGT ANPEP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
AGT AOPEP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
AGT CPA3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
AGT CTSG â—¼   CLEAVAGE ✅ + 0.64 0.64 Signor
AGT CTSG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
AGT CTSZ â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
AGT ELANE â—¼   CLEAVAGE ✅ + 0.27 0.27 Signor
AGT ENPEP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
AGT MME â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
AGT PRTN3 â—¼   CLEAVAGE ✅ + 0.26 0.26 Signor
AGT REN â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
AGT REN â—¼   CLEAVAGE ✅ 1.0 0.7 intact
AKT1 CASP3 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
AKT1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
AKT2 CASP3 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
AKT2 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
AKT3 CASP3 â—¼   CLEAVAGE ✅ 0.56 0.56 mint
AKT3 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
ALB ACE2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ANPEP AGT â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
ANTXR1 FURIN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
ANTXR2 FURIN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
AOPEP AGT â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APAF1 CASP3 â—¼   CLEAVAGE ✅ 0.65 0.65 mint
APAF1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
APAF1 CASP9 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
APC CASP3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
APH1A APP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1A ERBB4 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1A ITGB3BP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1A NGF â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1A NGFR â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1A TRAF6 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1B APP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1B ERBB4 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1B ITGB3BP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1B NGF â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1B NGFR â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APH1B TRAF6 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APLN ACE2 â—¼   CLEAVAGE ✅ + 0.38 0.38 Signor
APOA1 BMP1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
APOH F10 â—¼   CLEAVAGE ✅ - 0.39 0.39 Signor
APOH PLG â—¼   CLEAVAGE ✅ - 0.45 0.45 Signor
APP ADAM10 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
APP ADAM17 â—¼   CLEAVAGE ✅ + 0.52 0.52 Signor
APP ADAM17 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
APP APH1A â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APP APH1B â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APP BACE1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
APP BACE1 â—¼   CLEAVAGE ✅ + 0.76 0.76 Signor
APP BACE2 â—¼   CLEAVAGE ✅ + 0.52 0.52 Signor
APP CASP6 â—¼   CLEAVAGE ✅ + 0.73 0.73 Signor
APP CTSD â—¼   CLEAVAGE ✅ 0.44 0.44 mint
APP CTSD â—¼   CLEAVAGE ✅ 0.44 0.44 mint
APP KLK6 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
APP NCSTN â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
APP PITRM1 â—¼   CLEAVAGE ✅ - 0.38 0.38 Signor
APP PSENEN â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
AREG ADAM17 â—¼   CLEAVAGE ✅ + 0.4 0.4 Signor
AREG SRC â—¼   CLEAVAGE ✅ + 0.31 0.31 Signor
ARHGDIB CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
ARHGDIB CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
ATF6 MBTPS1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
ATF6 MBTPS2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
ATG16L1 CASP1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ATG16L1 CASP3 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ATG16L1 CASP6 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
ATG4B GABARAP â—¼   CLEAVAGE ✅ + 0.84 0.84 Signor
ATG4B GABARAPL2 â—¼   CLEAVAGE ✅ + 0.83 0.83 Signor
ATG4B MAP1LC3B â—¼   CLEAVAGE ✅ 0.95 0.95 mint
ATG4B MAP1LC3B â—¼   CLEAVAGE ✅ 2.0 0.8 intact
ATG4B MAP1LC3C â—¼   CLEAVAGE ✅ + 0.73 0.73 Signor
ATP6V1G1 3C-like proteinase â—¼   CLEAVAGE ✅ - 0.2 0.2 Signor
AXIN1 USP34 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
AXIN2 USP34 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
Angiotensin 1-7 ACE2 â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
Angiotensin-1 ACE2 â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
Angiotensin-1 REN â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
Angiotensin-2 ACE â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
Angiotensin-2 DPP3 â—¼   CLEAVAGE ✅ - 0.2 0.2 Signor
BACE1 APP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
BACE1 APP â—¼   CLEAVAGE ✅ + 0.76 0.76 Signor
BACE1 IAPP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
BACE2 APP â—¼   CLEAVAGE ✅ + 0.52 0.52 Signor
BACE2 IAPP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
BACE2 IAPP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
BACE2 INS â—¼   CLEAVAGE ✅ 1.0 0.7 intact
BAD CASP3 â—¼   CLEAVAGE ✅ + 0.5 0.5 Signor
BCAP31 CASP8 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BGLAP CTSB â—¼   CLEAVAGE ✅ - 0.33 0.33 Signor
BGLAP CTSD â—¼   CLEAVAGE ✅ - 0.32 0.32 Signor
BGLAP CTSH â—¼   CLEAVAGE ✅ - 0.3 0.3 Signor
BGLAP CTSL â—¼   CLEAVAGE ✅ - 0.2 0.2 Signor
BGLAP CTSS â—¼   CLEAVAGE ✅ - 0.32 0.32 Signor
BGLAP FURIN â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BID CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
BID CASP8 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BID CASP8 â—¼   CLEAVAGE ✅ + 0.89 0.89 Signor
BID GZMB â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BIRC2 CASP3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BMP1 APOA1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
BMP1 CHRD â—¼   CLEAVAGE ✅ 2.0 0.8 intact
BMP1 CHRD â—¼   CLEAVAGE ✅ 0.62 0.62 mint
BMP1 COL1A1 â—¼   CLEAVAGE ✅ + 0.67 0.67 Signor
BMP1 COL3A1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
BMP1 COL5A1 â—¼   CLEAVAGE ✅ + 0.62 0.62 Signor
BMP1 COL5A2 â—¼   CLEAVAGE ✅ + 0.6 0.6 Signor
BMP1 COL7A1 â—¼   CLEAVAGE ✅ + 0.6 0.6 Signor
BMP1 HSPG2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
BMP1 LAMA3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BMP1 LAMB3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BMP1 LAMC2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BMP1 LOX â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
BMP1 LOXL1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
BMP1 MSTN â—¼   CLEAVAGE ✅ 0.62 0.62 mint
BMP1 MSTN â—¼   CLEAVAGE ✅ 0.62 0.62 mint
BMX CASP3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
BRCA1 CASP3 â—¼   CLEAVAGE ✅ - 0.46 0.46 Signor
BTC ADAM10 â—¼   CLEAVAGE ✅ + 0.34 0.34 Signor
BTC ADAM17 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C1QA C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QA C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QA C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QB C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QB C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QB C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QBP F12 â—¼   CLEAVAGE ✅ 8.0 1.0 Reactome
C1QBP PRCP â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
C1QC C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QC C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1QC C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1R C1S â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C1R C2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1R C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1R C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1RL HP â—¼   CLEAVAGE ✅ + 0.38 0.38 Signor
C1S C1R â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C1S C2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C1S C2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C1S C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1S C4B_2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C1S SERPING1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C2 C1QA â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 C1QB â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 C1QC â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 C1R â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 C1S â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C2 C1S â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C2 C5 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C2 COLEC10 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 COLEC11 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 IGHG1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 IGHG2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 IGHG3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 IGHG4 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 IGKC â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 MASP1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 MASP1 â—¼   CLEAVAGE ✅ + 0.53 0.53 Signor
C2 MASP2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C2 MBL2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C3 C5 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C3 CFB â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C3 CFD â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
C3 CFI â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C3 CFI â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C3 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
C3 CPN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
C3 CPN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
C3 CTSG â—¼   CLEAVAGE ✅ + 0.59 0.59 Signor
C4A C1QA â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A C1QB â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A C1QC â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A C1R â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A C1S â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A C4B_2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C4A C5 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C4A COLEC10 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A COLEC11 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A IGHG1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A IGHG2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A IGHG3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A IGHG4 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A IGKC â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A MASP1 â—¼   CLEAVAGE ✅ + 0.56 0.56 Signor
C4A MASP1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A MASP2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4A MASP2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C4A MBL2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B MASP1 â—¼   CLEAVAGE ✅ + 0.65 0.65 Signor
C4B MASP2 â—¼   CLEAVAGE ✅ + 0.8 0.8 Signor
C4B_2 C1QA â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 C1QB â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 C1QC â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 C1R â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 C1S â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 C4A â—¼   CLEAVAGE ✅ 1.0 0.7 intact
C4B_2 C5 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C4B_2 COLEC10 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 COLEC11 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 IGHG1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 IGHG2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 IGHG3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 IGHG4 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 IGKC â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 MASP1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 MASP2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C4B_2 MBL2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
C5 C2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C5 C3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C5 C4A â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C5 C4B_2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C5 CFB â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C5 CFP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
C5 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
C5 CPN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
C5 CPN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
C5 F2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CAPN1 CAPNS1 â—¼   CLEAVAGE ✅ 0.73 0.73 mint
CAPN1 CDH1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CAPN1 CDK5R1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CAPN1 EZR â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CAPN1 EZR â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CAPN1 F2R â—¼   CLEAVAGE ✅ + 0.4 0.4 Signor
CAPN1 F2RL1 â—¼   CLEAVAGE ✅ - 0.31 0.31 Signor
CAPN1 FLG â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
CAPN1 GSK3A â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
CAPN1 GSK3B â—¼   CLEAVAGE ✅ + 0.28 0.28 Signor
CAPN1 MAPT â—¼   CLEAVAGE ✅ - 0.3 0.3 Signor
CAPN1 PTPN1 â—¼   CLEAVAGE ✅ 0.68 0.68 mint
CAPN1 TIRAP â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CAPN2 CDK5R1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CAPN2 F2RL1 â—¼   CLEAVAGE ✅ - 0.31 0.31 Signor
CAPN2 GSK3A â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
CAPN2 GSK3B â—¼   CLEAVAGE ✅ + 0.27 0.27 Signor
CAPN2 MAPT â—¼   CLEAVAGE ✅ - 0.43 0.43 Signor
CAPN2 TNS1 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CAPN2 TNS1 â—¼   CLEAVAGE ✅ 3.0 0.9 intact
CAPN3 CDK5R1 â—¼   CLEAVAGE ✅ + 0.25 0.25 Signor
CAPN3 GSK3A â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
CAPN3 GSK3B â—¼   CLEAVAGE ✅ + 0.26 0.26 Signor
CAPN3 MAPT â—¼   CLEAVAGE ✅ - 0.3 0.3 Signor
CAPNS1 CAPN1 â—¼   CLEAVAGE ✅ 0.73 0.73 mint
CAPNS1 CDH1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CAPNS1 CDK5R1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CAPNS1 FLG â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
CAPNS2 CDK5R1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP1 ATG16L1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP1 CTSG â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP1 GSDMD â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP1 IL18 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
CASP1 IL1B â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP1 PSEN1 â—¼   CLEAVAGE ✅ + 0.38 0.38 Signor
CASP1 PSEN2 â—¼   CLEAVAGE ✅ + 0.33 0.33 Signor
CASP1 RNF31 â—¼   CLEAVAGE ✅ - 0.2 0.2 Signor
CASP12 CASP9 â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor
CASP14 CDSN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP14 FLG â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
CASP14 LCE1A â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP14 LCE3D â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP2 MDM2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 ACIN1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 ADD1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 AKT1 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP3 AKT2 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 AKT3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 AKT3 â—¼   CLEAVAGE ✅ 0.56 0.56 mint
CASP3 APAF1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 APAF1 â—¼   CLEAVAGE ✅ 0.65 0.65 mint
CASP3 APC â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome
CASP3 ARHGDIB â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 ATG16L1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 BAD â—¼   CLEAVAGE ✅ + 0.5 0.5 Signor
CASP3 BID â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 BIRC2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 BMX â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 BRCA1 â—¼   CLEAVAGE ✅ - 0.46 0.46 Signor
CASP3 CASP6 â—¼   CLEAVAGE ✅ + 0.64 0.64 Signor
CASP3 CASP6 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 CASP8 â—¼   CLEAVAGE ✅ + 0.77 0.77 Signor
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP3 CDH1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 DBNL â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 DCC â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome
CASP3 DFFA â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 DFFA â—¼   CLEAVAGE ✅ + 0.74 0.74 Signor
CASP3 DFFB â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 DFFB â—¼   CLEAVAGE ✅ + 0.65 0.65 Signor
CASP3 DSG1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 DSG2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 DSG3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 DSP â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 FNTA â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 GAS2 â—¼   CLEAVAGE ✅ + 0.43 0.43 Signor
CASP3 GAS2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP3 GATA1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 GORASP1 â—¼   CLEAVAGE ✅ - 0.4 0.4 Signor
CASP3 GRIPAP1 â—¼   CLEAVAGE ✅ + 0.41 0.41 Signor
CASP3 GSN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP3 GSN â—¼   CLEAVAGE ✅ - 0.63 0.63 Signor
CASP3 IKBKB â—¼   CLEAVAGE ✅ - 0.34 0.34 Signor
CASP3 KDM4C â—¼   CLEAVAGE ✅ - 0.2 0.2 Signor
CASP3 MAPT â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 MDM2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 MYL3 â—¼   CLEAVAGE ✅ - 0.38 0.38 Signor
CASP3 NFKBIA â—¼   CLEAVAGE ✅ + 0.4 0.4 Signor
CASP3 NMT1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 NMT2 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 NUCB2 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP3 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 OCLN â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 PAK2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 PANX1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 PARP1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 PARP1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP3 PKP1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 PRKCD â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 PRKCQ â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP3 PSEN1 â—¼   CLEAVAGE ✅ + 0.44 0.44 Signor
CASP3 PSEN2 â—¼   CLEAVAGE ✅ + 0.4 0.4 Signor
CASP3 PSIP1 â—¼   CLEAVAGE ✅ - 0.36 0.36 Signor
CASP3 PTCH1 â—¼   CLEAVAGE ✅ - 0.29 0.29 Signor
CASP3 PTGES3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 RAD51 â—¼   CLEAVAGE ✅ - 0.47 0.47 Signor
CASP3 ROCK1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 SAV1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 SPTAN1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 STK24 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP3 STK26 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 STK3 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 STK4 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP3 TJP1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 TJP2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 TXN â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP3 UNC5A â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 UNC5B â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP3 VIM â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP4 GSDMD â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP5 GSDMD â—¼   CLEAVAGE ✅ + 0.59 0.59 Signor
CASP6 APP â—¼   CLEAVAGE ✅ + 0.73 0.73 Signor
CASP6 ATG16L1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP6 CASP3 â—¼   CLEAVAGE ✅ + 0.64 0.64 Signor
CASP6 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP6 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP6 CASP8 â—¼   CLEAVAGE ✅ + 0.77 0.77 Signor
CASP6 CASP8 â—¼   CLEAVAGE ✅ + 0.77 0.77 Signor
CASP6 LMNA â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP6 LMNA â—¼   CLEAVAGE ✅ - 0.65 0.65 Signor
CASP6 LMNB1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP6 NUCB1 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP6 NUCB1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP6 NUCB2 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP6 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP6 PARP10 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP6 PARP10 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP6 PSEN1 â—¼   CLEAVAGE ✅ + 0.37 0.37 Signor
CASP6 PSEN2 â—¼   CLEAVAGE ✅ + 0.36 0.36 Signor
CASP6 SATB1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP6 VIM â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP7 ARHGDIB â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP7 CASP6 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP7 CASP8 â—¼   CLEAVAGE ✅ + 0.78 0.78 Signor
CASP7 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP7 CASP9 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome
CASP7 CLSPN â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP7 GAS2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP7 HTRA4 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP7 NUCB2 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP7 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP7 PANX1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP7 PARP1 â—¼   CLEAVAGE ✅ - 0.7 0.7 Signor
CASP7 PSEN1 â—¼   CLEAVAGE ✅ + 0.35 0.35 Signor
CASP7 PSEN2 â—¼   CLEAVAGE ✅ + 0.33 0.33 Signor
CASP7 PTGES3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP7 PTK2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP7 STK24 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP7 VIM â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 BCAP31 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 BID â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 BID â—¼   CLEAVAGE ✅ + 0.89 0.89 Signor
CASP8 CASP3 â—¼   CLEAVAGE ✅ + 0.77 0.77 Signor
CASP8 CASP6 â—¼   CLEAVAGE ✅ + 0.77 0.77 Signor
CASP8 CASP6 â—¼   CLEAVAGE ✅ + 0.77 0.77 Signor
CASP8 CASP7 â—¼   CLEAVAGE ✅ + 0.78 0.78 Signor
CASP8 FADD â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 IL1B â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome
CASP8 NMT1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP8 NUCB1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP8 NUCB1 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP8 NUCB2 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP8 NUCB2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP8 PARP10 â—¼   CLEAVAGE ✅ 0.44 0.44 mint
CASP8 PARP10 â—¼   CLEAVAGE ✅ 2.0 0.8 intact
CASP8 PLEC â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 PSEN1 â—¼   CLEAVAGE ✅ + 0.37 0.37 Signor
CASP8 PSEN2 â—¼   CLEAVAGE ✅ + 0.34 0.34 Signor
CASP8 RIPK1 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 RIPK1 â—¼   CLEAVAGE ✅ - 0.9 0.9 Signor
CASP8 RNF31 â—¼   CLEAVAGE ✅ - 0.29 0.29 Signor
CASP8 TRADD â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 TRAF2 â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP8 VIM â—¼   CLEAVAGE ✅ 1.0 0.7 Reactome
CASP9 APAF1 â—¼   CLEAVAGE ✅ 1.0 0.7 intact
CASP9 CASP12 â—¼   CLEAVAGE ✅ + 0.2 0.2 Signor