CTNNB1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NFE2L2
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
NFE2L2
|
KEAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
NFE2L2
|
KEAP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19560419
23850759
|
HSP90AB1
|
KEAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20864537
26517842
|
RBX1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15983046
22872865
|
RBX1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15572695
19560419
|
SQSTM1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15983046
22872865
|
NFE2L2
|
CUL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21793854
20452971
|
NF2L2
|
ENC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
20511222
18981988
17875699
|
ENC1
|
NUDC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ENC1
|
ENC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ENC1
|
PLIN5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FBXL17
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ENC1
|
CUL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21145461
15983046
33961781
|
CUL3
|
ENC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
22578813
27664236
33961781
33130828
21145461
|
CUL3
|
NUDC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21145461
33961781
|
KEAP1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
ENC1
|
RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9566959
16189514
16306221
|
KEAP1
|
NF2L2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31541481
17822677
22558124
30122040
16790436
28533375
31257023
11439354
23727018
20027226
24844779
27212020
18757741
23722832
34526658
15572695
18417180
17462537
32911434
21262351
19706542
29423025
15985429
32206121
19920073
24011591
31169361
30793592
15475350
30765703
28638054
28186440
29792731
20463144
30778200
28534518
25628777
14585973
32159343
28939422
23382044
33391509
16785233
29255090
26536456
31941496
24704364
12145307
17015834
31262713
27091842
18387606
23645672
16449638
14517290
9887101
20484052
20599909
23066931
22448038
16888629
21383067
11909699
25582950
20486933
28416489
33393215
30473361
16006525
23986495
22331464
20421418
15601839
29033244
24512214
30383469
32605589
31695040
21988832
27621311
28617433
24130096
18981988
30126895
22245129
23857982
24322982
22302998
30692632
22215675
30576774
31891690
32057361
32854194
20864537
26078718
30465941
|
KEAP1
|
CUL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22911784
21357422
19818716
17822677
16449638
15367669
30765703
22558124
28186440
33130828
17439941
20599909
15282312
21145461
22448038
25742418
26757824
16790436
32296183
24896564
20534351
23727018
18251510
24127568
20027226
22245129
15983046
24322982
32341456
25628777
20421418
15572695
33391509
18417180
20865015
15601839
32854194
30273379
30383469
20864537
26219975
|
CTNNB1
|
TCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.93
|
STRING
|
36370105
|
TCF4
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5219694
17318191
|
CUL3
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
19818716
15448697
12481031
11861641
30349055
25270598
20027226
22405651
26100637
19256485
11311237
19250909
25278611
26286618
20865015
15601839
19617556
29958295
33504946
12684064
24145166
|
KEAP1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CUL3
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
KEAP1
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CUL3
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
SQSTM1
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
23850759
25002027
26587781
26653790
26794443
27048822
28574505
|
RBX1
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
SQSTM1
|
KEAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
23850759
25002027
26587781
26653790
26794443
27048822
28574505
|
CUL3
|
KEAP1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
RBX1
|
KEAP1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
SQSTM1
|
KEAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
20378532
35044719
20495340
25416956
25939382
23117207
32075457
20452972
24322982
20562859
25910212
26043024
33397898
23795962
27631370
33603948
20421418
32296183
23242280
19615732
31169361
20173742
24011591
21482715
|
KEAP1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
104.0
|
1.0
|
Omnipath
|
30122040
17020408
31257023
35380342
16449638
22245129
18417180
28939422
15475350
24130096
20421418
12145307
32057361
17462537
23727018
24704364
34894983
23857982
19920073
31262713
20599909
36038548
24997453
17015834
23722832
21988832
30778200
24322982
36333711
20486933
30465941
22448038
30576774
21262351
23645672
16888629
31169361
11909699
26078718
25582950
19706542
20463144
16006525
18694732
11439354
15985429
15572695
34815381
28186440
23066931
19560419
15601839
23986495
25628777
27212020
22302998
30793592
16790436
26536456
24512214
17822677
20027226
28533375
22215675
29423025
14517290
32911434
20484052
14585973
18387606
23382044
21383067
32159343
18757741
27091842
24011591
9887101
31941496
22558124
36165926
|
KEAP1
|
CUL3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20534351
30273379
15983046
24896564
15282312
17439941
32341456
26219975
32296183
26757824
|
RBX1
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
16790436
32284348
24366543
15601839
19321346
17081101
23986495
15367669
15572695
9887101
17785452
15282312
|
RBX1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
RBX1
|
CUL3
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
SQSTM1
|
RBX1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
14744430
15340068
16252010
18545270
19427028
20531300
21981924
25002027
26587781
28574505
|
RBX1
|
NFE2L2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
SQSTM1
|
CUL3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
14744430
15340068
16252010
18545270
19427028
20531300
21981924
25002027
26587781
28574505
|
NFE2L2
|
SQSTM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23382044
19762340
17189831
20452972
24416372
|
CUL3
|
NFE2L2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
CTNNB1
|
TCF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12086873
11943708
13679048
15806138
|
CTNNB1
|
TCF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
24532795
11713475
18281465
25402006
16724116
12799378
12944908
12727872
23331499
15060161
17412698
22080605
21743491
17875931
12657632
17983804
20126258
17318191
24798214
24876153
29361949
17909039
23449499
22699938
18595660
9308964
16007074
15331612
11713476
15665104
17072306
15525529
17962194
|