Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 NFATC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
PRKCD APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CREB1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11116137
STAT3 GAP43 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26865625
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
TP53 ANKRD11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18840648
TP53 ID2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16557594
PRKCA ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCF12 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16549780 0600168103
PRKCA GAP43 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2562806 7891109
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CEBPB PCK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8093246
DRD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEUROD2 NEUROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816493 21593321
NEUROD1 GAP43 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816493 12562512
NEUROD1 NEUROD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8816493 17924961
DRD4 GAP43 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LYPLA2 GAP43 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14978216 21152083
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
NEUROD1 TCF12 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CALM1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CUL4B EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23238014 24292684 27634302
APP NCSTN â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
PRKCB PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
ID2 TCF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9242638
ID2 TCF12 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
APP PSEN1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NCSTN PSEN1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
PRKCD STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 76.0 1.0 Omnipath 8272872 19413330 11335711 15677447 9343414 15465816 8140422 12576423 11350938 7678052 20068231 12754507 9880505 12763138 9872331 18491316 18669648 8662591 10521505 18691976 27036017 27458446 7537214 8626374 20058876 25280942 16951338 14551213 8164674 12754506 10446219 12361954 12754505 16418226
PRKCA PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14576165
NCSTN PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 12603837 23331499 21071413 14572442 12471034 10993067 18201567 18988627 12032140
STAT3 CEBPB â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
CEBPB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11134330 18266962
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
TP53 LITAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10321740 21836606 17283168 15197774
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
CSNK2A1 CALM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 25108821 11827172 8206911 1520270 17173306 17329434 26675311 8639568