Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAD23B BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16712842 5218673
KPNA2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9497340 6547667
BRCA1 KPNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221252 8955125
EZH2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23624935 21406404
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
BRCA1 KRT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16241993 19882246
ELAVL1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19010922
MTA1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17922032
STK11 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 34591612
DCUN1D2 CUL4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
DCUN1D2 CUL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
CUL5 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DDB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
XPC DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
DHX9 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DHX9 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DHX9 DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSP90AB1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJA1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HNRNPK ELAVL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
ELAVL1 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17317627
ELAVL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19884656
EP300 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20660371 19102934
EP300 KRT16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12954631 16214953
LRRK2 FANCM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
HSP90AA1 GIGYF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
SNRPB GIGYF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16120600 5217924
HNRNPDL TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8200620 21821029
SYNCRIP HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX56 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TXN HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KPNA1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22500989 8328086
PCNA POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660172 2165567
POLA2 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
POLA2 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NCOR1 SNAI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18588516 20101232
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
CRBN SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
DNMT3B SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
EZH2 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980680 17584191
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
SALL2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082782 24040083
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 NFKB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808109 22701761
TP53 KRT14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22911849 22577164
TP53 MTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23552838 22286760
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
TP53 TXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16096367
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 ACTA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17409411
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
PCNA XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
YBX1 KPNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
ATP1A1 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PCNA ALDOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
PCNA ALDOA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
DCUN1D2 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
DCUN1D3 CUL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
DCUN1D2 CUL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
C1QBP HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPF TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DNMT3B JUP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16887905 17998942
FGFR3 OIP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCUN1D1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ILF2 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMAD7 KRT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23475202 17499880
SNRNP70 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HDAC1 GPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
MTA1 HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791785 16511565
NCOR1 PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCUN1D3 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
DCUN1D2 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
LRRK2 KDM4D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
EZH2 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21465172 19351856
RPL27A CAND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AB1 NLRP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29712950 17435760
TUBA4A ENO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HDAC6 TUBA4A â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
HDAC6 TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024216
SYNCRIP RPL24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPL27 RPL24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPL6 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM27 DNMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MYCBP2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
AHR HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2153080 18805402
HSPA5 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FBXW11 NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
HNRNPA3 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MICAL1 H2BC21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MTA1 MTA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26028330 18719363
EZH2 FBXO32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21546904 24213577
EZH2 KRT9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23933322 24652950
DDX1 ZFP64 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DDX1 RTRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 REST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYCBP2 LDHB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
JARID2 KRT9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19010785 22110129
H2BC21 NSD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 KDM4D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 SSB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 HSPA7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
COPS7A CRBN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
RPS6 TBL3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DDB1 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 34026424 25189618 24249678 26679995
DTL CDT1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21930785 30623174 24906324 26272819
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
HUWE1 PCNA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25147182 22203964 27146073
KRT24 KRT5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
GPS2 NCOR1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CCNE1 PCNA â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
PHF1 RBBP7 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
BRCA1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
WDR76 CBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
LRRK2 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
DNMT1 CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17470536 12867029
CBX5 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 28225217
CUL4B DCAF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31155351
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
CUL5 PRDX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33712558
DDB1 BRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 16964240
DDB1 AHR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19651607 17392787
GLMN DTL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
DCAF7 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35016035 31753913
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
FOXP1 CTBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30585266 25609649
EZH2 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
CUL4A WDR76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30655611 17041588
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
UBXN7 CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CUL4A GRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17079684 17041588
CUL4A DCAF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31155351
SART3 NOC4L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBXN7 WDR11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN7 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
UBXN7 BRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN7 BRWD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
BMI1 ILF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
MTA1 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12920132 24981860
LRRK2 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
NEDD8 DCAF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18247557
NEDD8 DDX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
BMI1 RTCB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
CAND1 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 21145461
PRDX1 PRDX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
CTBP1 EZH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31041561 27634302
GLMN DCAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HSP90AA1 STK11 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
FUS SYNCRIP â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
AMBRA1 CUL4A â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
NOC4L RPS6 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
UBXN7 CUL4B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22466964 18775313 31973889
CUL4B PHF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23238014 29846670
DDB1 NEDD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16503656 18274552 16964240 21145461 18247557
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
PHF1 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18285464 18385154 27705803 29846670 33961781 24981860
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
WDR76 XPC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27248496 31353912
PCNA CCNE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CUL4A BRWD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 31973889 16964240
CUL4A GLMN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22405651 33961781
CUL2 GLMN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22405651 33961781
EZH2 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27634302 27705803
AP2A1 RBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 10764745 31980649
AMBRA1 DDB1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HNRNPF HNRNPH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
SNRNP40 SNRNP70 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
KRT1 KRT14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GNL3 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TP53 USP10 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
COMMD1 CUL2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBX1 SUV39H1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KRT10 KRT5 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
BRCA1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25531315 23624935
EZH2 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23238014 27634302
SUZ12 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23238014 27634302
CDT1 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22451935 15448697
CUL4A CDT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17079684 14578910 15448697
FUS ILF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27460707 29884807
DNMT3B EZH2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DNMT1 MTA1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
KRT1 KRT24 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
MTA1 TP53 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
C1QBP YBX1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
WDTC1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 27113764 31973889 33961781 16949367
MTA1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 26028330
GLMN CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 31973889
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B BRWD3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31753913 26496610 31973889
CUL4B SIN3A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
DDB1 PHF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23238014 29846670
FUS DHX9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807
ILF2 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
HDAC1 ERCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31722399 26496610 26030138
PHF1 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
UBXN7 NEDD8 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24076655 22466964 22537386
SMAD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10199400 11226163 31130994 14699069
NEDD8 AHR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12215427
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
CUL2 UBXN7 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CDT1 DTL â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CCNE1 CUL3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL4B SRSF3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B PPIA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B DHX9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B PRDX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
LRRK2 DDB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 24725412
FANCM PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 33961781 26825464
FUS HNRNPR â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
ELAVL1 HNRNPK â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
LRRK2 CDC37 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18367605 22612223 20642453 26355680 16321986 23075850
CUL4B GRWD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 30945288 17041588
CUL4B SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 27634302
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
DDB2 XPC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22039351 23319653 28760956 27203177 29604309 15882621
DHX9 ILF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 22939629 23986595
PHF1 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18285464 18385154 27705803 29846670 33961781 23273982 24981860 27634302 24457600
EZH2 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194 27634302 24457600
SUZ12 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 35016035 26186194 24981860 12435631 27634302 24457600 31281901 20075857
LARP1 ILF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 23986595
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
HDAC1 REST â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18806873 10491605
DNMT1 MTA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27728808 26344197 21670149 23708667
MTA3 MTA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21258344 24981860 26344197
GPS2 RBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 31980649 33961781 21516116
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS7A DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ERCC6 ERCC8 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SYNCRIP YBX1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SNRNP40 SNRPB â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CUL3 DCUN1D3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 NAP1L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CUL2 DCUN1D2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CUL2 DCUN1D3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDC37 LRRK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MDM2 RPS7 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CTBP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21102443 16713569 10196224 31636387 11751867
BRCA1 CBX3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 23074186 25634209 25184681
CRBN CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24292625 31973889 33961781 21145461 27142104 27294876
ERCC8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 26496610 33961781 21145461 22902626
DCAF4 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 21145461 30945288 16949367 32140073
DCAF8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33288900 33961781 31155351 21145461 16949367
CUL4B DTL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21628527 17041588 31973889 24962565 23555860 16861906 26496610 33961781 31155351 21145461 16949367
CUL4B PRDX3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 28225217 21795677
DTL CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21628527 17041588 23478441 31973889 23555860 16861906 29424068 30623174 31155351 33961781 30649446 21145461 16949367
AHR EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10999956 17392787 21988832
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
ERCC8 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 12732143 29225035 21145461 16751180 26826127 22902626
FOXP1 CTBP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14701752 31041561
MDM2 CTBP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12867035 21057548
DCAF8 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32235678 31973889 33288900 33961781 31155351 21145461 19295130 16949367
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
CUL4A DCAF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33961781 16964240 21145461 30945288 16949367 32140073
CUL4A WDTC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27113764 31973889 33961781 16964240 21145461 30945288 16949367
UBXN7 CUL2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26389662 22537386 22466964 18775313 21145461
NOC4L KRR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
CUL3 CCNE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31636116 27477274 10500095 17192413
DDX1 RTCB â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CUL4A ERCC8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTBP1 CTBP2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
COPS7A CUL4A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AHR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNRNPA1 HNRNPR â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
KRR1 RPS7 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21102443 10220405 16713569
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
CUL4B EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23238014 24292684 27634302
ERCC8 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16949367 22232169 28416769 29531219 17392787 12732143 31970402 16751180 26826127 22902626
DCAF8 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32703400 31257023 32235678 33288900 31391242 19966799 33961781 24500646 31155351 16964240 19295130 16949367
DDB1 DCAF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19966799 33961781 16964240 30945288 16949367
DDB1 DTL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21628527 17041588 23478441 16861906 29424068 30623174 33961781 31155351 30649446 16964240 33536335 16949367
DDB1 WDTC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27113764 19966799 33961781 16964240 16949367
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EZH2 PHF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 18285464 18385154 26496610 27705803 29846670 28068325 33961781 23273982 24981860 11571280 23142980 27634302 24457600
MTA3 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26028330 27705803 21258344 33961781 24981860 26186194
PCNA DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20940144 20613874 24958773 9302295 26496610 30301766 12354094 23708667 22606318 10888872
CUL4A CRBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24292623 24292625 31973889 32235678 23983124 26231201 25860244 26990986 27029275 33961781 16964240 32132601 21145461 27142104 20223979 27294876
HDAC1 MTA3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12705869 23752268 28514442 34026424 22075476 26028330 26496610 21258344 33961781 24981860 18451879 26344197
CDT1 GRWD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25990725 18162579
CTBP2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31041561 16189514 25416956 16713569 21988832 28947780 30585266 26496610 33961781 35016035 26186194 24722188 27107012 9858600 26344197
DNMT1 EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31130994 16357870 22094255 28068325 21378168
RTCB DDX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24608264 22863883 33961781 27173435 24981860 29395067 22939629 30833792 26344197
CBX5 SUV39H1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
KRT16 KRT5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
RBBP7 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11394910 10220405 16713569 11746496
DHX9 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9662397 26831064 16713569 12592385
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
EZH2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19079346 20574448
CBX1 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 27705803 33961781 21888893 24981860 34079125
CBX5 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 20850016 27705803 20231385 33961781 21888893 24981860 15306854 34079125 20562864 19498464
TP53 CDC25A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18281511 17001315 19060337
CDC37 STK11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25036637 14676191 20562859 12489981 21860411 33961781 14668798 32707033
CETN2 XPC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21962512 17154534 28514442 11279143 26638075 27880911 28760956 33961781 22939629
ERCC6 CUL4B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
ERCC6 DDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CUL4A DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22952844 17079684 22118460 15448697 26613412 22910413 25349427 21145461 22474075 27462452 16473935 15811626 18606781 26231201 18593899 16678110 16964240 33536335 19295130 25982117 33759138 16260596 27113764 21113133 30898011 28886238 26976604 27203177 17392787 25795299 22939629 26344197 14739464 27294876 10585395 27573245 31911655 17041588 20870715 27203182 31973889 32235678 16861906 19966799 22342275 34251884 17626091 19287380 30945288 16949367 32140073
DDB1 CRBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23983124 29370161 28425720 24292625 26909574 26231201 25108355 25860244 16964240 27142104 24292623 26990986 30190590 27294876 26131937 32235678 29892083 27338790 32132601 20223979
DDB1 DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22118460 28035050 12050362 24249678 26410533 22822215 28416769 29262658 16473935 18593899 30923324 16678110 16964240 20368362 12812979 19295130 16751180 19109893 17360488 16260596 27203177 17392787 10777491 12151405 32985517 14751237 22039351 17041588 12732143 11564863 9418871 19966799 33961781 26186194 34251884 16949367
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
CUL4A DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 28514442 22118460 28035050 11564859 21145461 29262658 16473935 15811626 18593899 26496610 30923324 16964240 20368362 19295130 16751180 33759138 16260596 27203177 17609381 32985517 10585395 17041588 31973889 12732143 33961781 26186194 17626091 30945288 16949367
PCNA DTL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25154416 21725088 16861906 29424068 30301766 30623174 20129063
HDAC6 ELAVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18644987
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10801418 15342649
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
ERCC6 CUL4A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
ERCC6 ERCC8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32355176 29531219 20541997 22032989 29225035 7664335 16916636 31970402 16751180 26826127 22902626
GNL3 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24769896 18426907 19033382 21132010
HSP90AA1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14614132 15894266 15218035
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
PHF1 SUZ12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24457600 18285464
POLA2 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SIN3A RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9651585 17255935 27705803 33961781 24981860 26186194 12453419 15451426 11784859
TP53 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
TP53 HNRNPR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 CDCA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 KRT9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24492005 21617703 22466965
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
YBX1 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24832798 24446247 19261809
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
CDT1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407242 30018425 24423875 16861906 16482215 18162579 26272819 16362051 30301766 30623174 16407252 21930785
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMAD2 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21990365 17303001 15306544
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
MTA1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 27098840 21258344 33264408 9885572 26028330 26496610 14722073 20585571 21670149 22939629 18451879 34026424 23752268 29997244 16511565 26949739 10840944 33961781 11146623 24981860 17922035 12920132 26344197
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
GPS2 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12628926 11931768 33961781 26186194 14527417
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
TXN PRDX1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 21385867 10514471 17519234
LRRK2 PRDX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31046837 21850687 24459295
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
RBBP7 SIN3A â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CDC25A FBXW11 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ARID4B SIN3A â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
KRT1 KRT16 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NOC4L RPS7 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
MTA1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 6613464 18451879
BIRC5 CDCA8 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
PHF1 SUZ12 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HNRNPA1 HNRNPH1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
KRT16 KRT71 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRT24 KRT71 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
EZH2 PHF1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
MTA3 RBBP7 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CUL4B DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CUL4A DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
NOC4L TBL3 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
EZH2 RBBP7 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
HDAC1 MTA3 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CDCA8 BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219326 17099693
EZH2 JARID2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SUV39H1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RBBP7 SUZ12 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
NCOR1 SIN3A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17210713 11430826 16713569
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
MTA1 RBBP7 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DCAF4 DDB1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
MTA1 RBBP7 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 27098840 18067919 26028330 27705803 33961781 24981860 26186194 12920132
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
KRR1 TBL3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DHX9 PCNA â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CBX1 CBX5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17314413 11336697 27705803 24981860 21888893 20562864
DDB1 DTL â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
DCAF12 DDB1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
DTL PCNA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KRT1 KRT10 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KRT14 KRT5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CETN2 XPC â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
SART3 USP15 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DNMT1 PCNA â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
KRR1 NOC4L â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
DDB1 WDTC1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DDB1 ERCC8 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CRBN DDB1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CDT1 PCNA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EEF2 RPS25 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL15 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL27A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL27 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPLP1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPS20 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
EEF2 RPS6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPL6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SNRNP70 SNRPB â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPS7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HDAC1 MTA1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
JARID2 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27 RPS25 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL15 RPL27 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27 RPL27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27A RPS7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPS7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPLP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL24 RPL27 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27 RPS6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27 RPS20 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27 RPLP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPLP1 RPS20 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL15 RPS7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL15 RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL27A RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL27 RPL6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL27 RPS7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS20 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL6 RPS7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS20 RPS7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL27A RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL15 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS20 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS25 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL15 RPL24 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL15 RPL27A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL15 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL15 RPL6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL15 RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPL27A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPL6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPL6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPLP1 RPS7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL6 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS20 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS6 RPS7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPLP1 RPS25 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS25 RPS7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 APAF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12883670 11559530 15077176 18951482 11896574 17043642 15972851 11591730 11389439
TP53 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11591730 11559530 11423996 11389439
NLRP1 APAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11113115 17418785
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
BRCA1 DDB2 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
CTBP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20818429 21681822 23303449
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
CDC25A CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 7575488 18590585 8617791 17303408 18073536 1075565 17568790 18786381 17660363 15279786
XPC CETN2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
XPC CETN2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
ERCC8 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
CUL4B COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PCNA DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
ERCC8 DDB1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CAND1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 21463634 12504026 12609982 23535662 21863050
DDB1 COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB2 DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 54.0 1.0 Omnipath 9418871 17145710 16751180 27203177 22118460 17041588 20368362 18593899 16964240 12050362 19295130 22039351 11564863 16473935 16678110 17392787 24249678 19109893 12151405 26186194 12812979 16949367 18936169 22822215 14751237 10777491 26410533 16260596 19966799 17360488 12732143
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
PCNA DTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
DTL CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21145461 19231300 16949367
ELAVL1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18680106 12963828 18519672
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 12408818 10887155 15831498 21269274
ERCC8 ERCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22902626 16751180 7664335 20541997 16916636 26826127 22032989
ERCC6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 10882116 19221478 18784753
ERCC8 CUL4A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
GNL3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20664182 12464630 16713569
MDM2 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19249676 16360036 23092970
HNRNPK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18472002 16360036 23092970
HNRNPK MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19249676 16360036 23092970
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
HSP90AA1 AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9083006 9390191 7961671 8089152
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
SNAI2 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
SNAI2 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
SNAI2 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
RBBP7 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
SIRT1 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15205477 15744310 15989956 18687677 19590512 19960022
SIRT1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21071413 23331499 17098745
SIRT1 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18004385 19218236
SIRT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22395773 15175761 16713569
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
HDAC1 SNAI2 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
SNAI2 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SNAI2 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
SNAI2 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SNAI2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
SNAI2 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
SNAI2 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
AHR TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17070097 15111621 11191113 20478272
TP53 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 19363521 19470765 19067706 17124180 11714700 16432013 18698017 21443519 12235242 20236666 22266808 16595680 15361831 23838170 17916908 15087401 15377848 19018856 19439469 22503977 17699779 11965534 15657147 18022393 18027854
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
FBXO11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17145710 17098746
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
TP53 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19211844 11965534 11714700
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17991895 18384127 31235252 28073635 12354094 9302295
PCNA CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16407242 19231300 16362051 24423875 16482215 16407252 16861906
CUL4A COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
NCOR1 SMAD2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
TLE2 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
NCOR1 TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1XR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17620012 15060155 15601853 14980219
BIRC5 BUB3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
LRRK2 PRDX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21850687 24459295
NEDD8 COMMD1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
NEDD8 USP15 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 USP15 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 USP15 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
NFKB2 FBXW11 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
SUZ12 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170