Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRHL3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23291169 19136938
SMAD7 KRT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23475202 17499880
GRHL3 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11373277 16036112
VDR ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18602086 19460946
TFAP2A KRT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12024040
GRHL3 ARHGEF19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20643356
GRHL2 GRHL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IRF6 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
GRHL3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19798104 23303449 18676825
CDH1 IFNG â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
TFAP2A CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9328434 17224907 12391156 10523846 9632747 21377456 12903198
VDR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22213313 16061479 16804902
GRHL3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21315774 12714599 10949939 12769861 17379597 18524818
TFAP2A ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8610173 9571041 7559515
TFAP2A RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11835395 9632747 21850486 9776742