Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 GTF2IRD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 NOTCH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DLX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 SLC22A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FOXO3 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20211690 19807657
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17581882
CASP3 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18362891
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
KLF8 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21518760 12820964
TP73 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16526280 22842668
EGFR CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7945309
CLOCK PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15828232 15500444
CLOCK CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20930143 19922678
GRB2 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DHX9 DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 TOP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313881
E2F1 SP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18342022
E2F1 ETV4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687701
E2F1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18396012
MAPK3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14967450 22802261
EGFR E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16299810
E2F1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15574337
E2F1 MYCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12438307 18319725
E2F1 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15867358 18319725
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
E2F1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15867357
E2F1 HSPA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18840615
E2F1 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11857079 18319725
SHC3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
TBP EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9699517 8152794
SP3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20435036 20407012
EGR1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11830539
EGFR PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499
EGFR ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12196520
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16917507 5218981
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
HIPK2 EP300 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
FOXO3 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18268343 0706790105
FOXO3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12391153 15509806
FOXO3 SIRT1 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome 14976264 23665396
FOXO3 ABCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18347152
DVL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
GRB2 NR1H4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DLX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRB2 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
MECP2 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19820693 19225110
RUNX1 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
RUNX1 HIPK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
PRKCB MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 SOS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK3 GAB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217186 15356145
EGF MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17081983 16024629
PRKCB MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
MCL1 BMF â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 11546872 23850759
MCL1 BMF â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 11546872 23850759
AHR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114727 16091746
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
MYC SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18809243
MYC CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1321339 11266125
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
MYC EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18365874 11509655
E2F2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9988278
GATA3 NKX3-1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22848398 20855495
HSPA5 POLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17099721
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
SIRT1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24416313 12837246
SIRT1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16998810
SSRP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23613959 9687513
TBP TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7666533 17967894
TP63 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22496369 15750631
TNF RACK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080539 0908486107
HNF4A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20621834 16771709
ARNT TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15627257 23359428
NR1H4 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19028791 19864602
TP73 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21933882 17725714
TP63 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23071313 21933882
ETV4 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7896795
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
TP63 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15578720 15466179
TP63 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17632082 19719829
RACK1 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12692135 15467455
YBX1 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22361279 12963034
RUNX1 CDK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17431401 5219852
TCF3 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21788410
DNMT3B JUP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16887905 17998942
GLI1 JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21059263
JAK2 CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11443118 11124936
CRKL SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
CRK SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK DLX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GNAS ADCY4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
SOCS1 JAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10421843 6731094
JAK2 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
SRC JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 17158356
SP3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18065760 15554904
ARNT IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20511231 21104991
WNT3A AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10428961 8666229
SP1 KLF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18353772
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
HIF1A CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17382325 5219810
SP3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12200429 20096088
ETS2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12658630 18319327
CREBBP VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10406465
CREBBP TCF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9774110 9388250
CREBBP ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573436
SKP2 RUNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26778333 26091038
WNT6 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857724 8717036
GLI1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11719506
IGF2BP1 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19887615
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
HIF1A ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15922656 19828131
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20003295
DLX4 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16781829 10625617
LNX1 SRC â—¼   COLOCALIZATION 2.0 0.8 intact 6504434 17936276
TCF7 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16585583 24836425
DNMT1 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18586981 20223637
RUNX3 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
RUNX1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
E2F2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15574337
SP1 ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20045441 12560478
ETS2 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9639404 18059336
ETS2 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9207063
PPARA CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20146263 15314095
ESR2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138116 16423895
ABCB1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 15498565 5217256
CAV1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15976327
TBP EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15169879 9679659
EGF SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499 17673906
SP1 EGR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20121949 7384875
SP1 SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10801817 12816880
SP1 TFPI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12446683
SP1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9875228
SP1 ATP1A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 15462673
SP1 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20644166
SP1 PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12105191 20179320
SP1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15486968
SP1 CDC25B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23160377 21242964
EGR1 AKR1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12890669
EGR1 TFPI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12757776
TBP PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18204072 10196169
ESR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797124 20819530
RUNX2 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16476583 22713854
STAT5A SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23716134 24018353
RUNX1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16995417 12835475
RUNX1 LGALS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19020999
KMT2A RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23817177 22012064
E2F2 MYCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12438307 18319725
HDAC5 GATA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607926103 17075044
HDAC5 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 16613856
ESR1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11060032 21610700
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
TFCP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21655924 19966177
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
ESR1 HOXC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21683083 18414489
ESR1 TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23031797 18414489
ESR1 SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21820658 23192982
TBP GATA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17495528 14675539
HNF4A TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805548
SOS1 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
GAB1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
HSPA5 WNT9B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 SLC22A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNF4A SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12763030 22190905
NR1H4 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24498169 11706036
NR1H4 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14527955 24007921
NR1I2 CYP3A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21733184 15252010
NR1I2 CYP2A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19702528 17827782
TRPS1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16140555
ZNF354C RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16415564 12070276
VDR HR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847098 5216521
VDR ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18602086 19460946
VDR CYP3A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11991950
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MDM4 UBB â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
EP300 ETS2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14722092 10942770 10358095 15572696
HNF4A SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
PHB2 HDAC5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21081666 15140878
ESR1 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 21182205 19805454 20348541
EP300 KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
MYC RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC PHB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC TOP2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC SSRP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC ANXA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30081903
CRKL SOCS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25814554 29991678
SKP2 UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT2 UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
SP1 MECP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15109260 20385708
WNT7A WNT7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
WNT16 WNT11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CREBBP FOXO3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
LNX1 UBB â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
KMT2A UBB â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
GNAS SCTR â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
SHC3 GRB2 â—¼   RELOCALIZATION ✅ + 0.82 0.82 Signor 16829981
DHX9 TOP2A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12711669 15034300
EGFR ANXA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25136068 26320552
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
DNMT1 RUNX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15735013 28533407
NR1H4 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17333335 25675114
WNT3A WNT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BRAF MAPK1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SRC CBL â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6538879 18273061
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
ETV4 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9194565 14976201 35140242
FOXO3 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19592618 25609649 11896584
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
MYC TERT â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32140074 28628118 28205554
RUNX1 CDK6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17431401 25241761
CRK SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23397142 10962563 12615911
SRC LNX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17936276
EGR1 SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20121949 12569082
HDAC5 RUNX3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24229708 15138260
HNF4A NR1I2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15331348 16455805
CREBBP TCF3 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
JAK2 STAT5A â—¼   PHOSPHORYLATION ✅ + 0.84 0.84 Signor 9575217
RUNX1 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14752096 16917507
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
CRKL SOS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9162067 26496610 33961781 32203420 23397142
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
MYCN SP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18003922 21123453 20697349
EGR1 EP300 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
SOCS1 EGFR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22973453 29991678 12070153
EP300 RUNX3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24229708 15138260
MTOR MAPKAP1 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 21045808 8088164
MYC TBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15723054 8755740
VDR SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20371703 15919723 12796488 12893883 15604093 16434701 21917910
GAB1 CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 31980649
AXIN1 CSNK1A1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ESR1 FOXO3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NEDD4 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NEDD4 EGFR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR PIM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
ESR2 FOXO3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29509190 18312651
ESR1 FOXO3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18312651 11435445
SOCS1 GRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
MYC CDK6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22094256 28628118 28205554
CRK SOCS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10022833 25814554
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
ESR1 PHB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10938099 24051437 12943695 26052702 17932104 19805454 28555617 10359819 15140878
ESR1 TRPS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23403292 26153859 31527615
FZR1 SKP2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CSNK1A1 MDM4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC SKP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ESR1 PHB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CRK SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 SP3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
E2F1 SKP2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
JAK2 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24240702 9363897 10635327 16273093 23838182 10358079
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
AHR EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10999956 17392787 21988832
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
SKP2 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22770219 18243116 26593157
EP300 VDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 20089040 21988832
EP300 PPARA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9407140 10336495 18797151
SRC ESR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12095943 12630920 15604093 11013076 11032808
ESR1 GATA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
AHR TBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8794892 15641800 16713569
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRKL EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR STAT5A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRKL GAB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SHC3 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22973453 9685397 8610109 16273093 8662772 9507002
EGFR CRKL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 25402006 18271526 25754235 16729043 23397142
EP300 HIPK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16917507 29170424
ANXA2 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 12577067 7510700 9565634 19380743
MYC SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11274368 18003922 17418410 15780936 32115405
MYC SKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23277542 12769844 12963825 26038816 17157259 24259667
GAB2 CRKL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9660791 11334882 10871282
GAB1 CRK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12138161 16713569 24728074 19380743
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
SRC CAV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8910575 8632005 8621645 29720121
AHR ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15837795 19460354 12612060 27420286 17392787 10620335 9611253
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
ESR1 SP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10816575 16651265 31527615
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EGFR GAB1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
SRC ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11494128 17474147 12522270 11781820 17318191
CRKL ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16443220 22286129 7493940 14604282 8978305 9820532 18835194 9710592 33961781 8524328 19823681 7926767 16955467 24412932
ABL1 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23950177 16713569 17474147 14725908 9407116 9516488 8194526 19380743 19823681 7926767 16955467
ABL1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 16273093 25402006 7678409
ABL1 CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15556646 11494134 16713569 9174058 20675402 9195915 14604282 10829062 14725908 8626543 12475393 19380743 19823681 16955467
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
ABL1 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19783996
ABL1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26546517 25944899
VDR CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18832097 18259074
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
SRC CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29899407 17094785 16713569 18273061 7782294 12941616 10829062 31120930 15135048 17141222 18996392 8635998 11994282 22203672 19861161 16636290
CCND1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16061635 9039267 11073968
SP3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22334592 20435036
FOXO3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12391153 21294163
SKP2 E2F1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12097298 17471231 23868976 27720894 16170383 10559858
E2F1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18840615
E2F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24502362 17575144 15867357
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
SP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10547281 8657141 10850422
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
EGFR CRK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16729043 9642287 31980649 10595738 22973453 24658140 11956190 16273093 9617486 25402006 12198159 8875975 9480911
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
EGFR GAB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23066441 31980649 10913131 9890893 24658140 10648629 21278788 25402006 10734310 18271526 19401591 11432805
GATA3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
MYCN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
EP300 EGR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15225550 9806899 20089040 20018936
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
EP300 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12573436 10999956
FOXO3 RUNX3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16373335 16738314 12637528
MAPK3 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19282669
JAK2 GRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7500025 17474147 8536716 8950973
SHC3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16729043 12242309 16829981
BRAF MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
MAPK1 MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9867858 30225354
MAPK1 PCYT1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15788406
MAPK1 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19237534
MAPK1 ATP1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15069082 14976217
MAPK1 BMF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22258404
MAPK1 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
BRAF MAPK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
MAPK3 PCYT1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15788406
MAPK3 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
MAPK3 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19237534
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
MYC AKR1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC NOTCH4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10918582 18444242 11258956
MYC EPHX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC FGF9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC NFIL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
AXIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19131971 20399964
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
SP1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843607 20160399 23704280
SSRP1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15979198 8774705 24532586
STAT5A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402124 21356308 17525530
ETS2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10913190 22740135 12509451
ESR2 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP63 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19458633
TP63 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27132513 8258457 23071313
TP63 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
UHRF1 DNMT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20613874 22064703 19798101 33170271 17673620 29691401 19800870 21045206 29268763 33465813 21268065 21745816 24782312 27045799 19943104 17934516 28803780 31322780 27049577 26065575 24368767
CDK6 CCND2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 28628118 10022865 28205554 11360184 30217970 33961781 23602568 11358847 9178893
SP1 CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12840223 11297539
GNAS ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
JAK2 GAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15644415 12506011 10455108
AXIN1 DVL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10829020 29659741 23892894 21245303
APC2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9601641 10980707
SP1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353772
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
PGR ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
CAV1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11563984 23634843 22230296 19595769
ETV4 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15138262 19483189 17390339
ESR1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12138116 18414489
STAT5A EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18996136 12697691 21617857
SP1 CYP3A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11485307
SP1 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17376297 16304843
SP1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10919269 15664452 10845704
SP1 CD9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8760289
SP1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15100175 11495920
SP1 ABCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9865734 23765166
SP1 EAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18588995
SP1 EPHX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315822
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
EGR1 EAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18588995
RUNX1 PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14561740
SP3 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14567977 14645238
E2F2 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12438307
AKT2 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10869359
PRKCB BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1386920 17570479 12917261
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
ESR1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15358113 15499176 18299335
ESR1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17556531 12710998
AHR SOS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20950586
HNF4A ABCG8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21123766 17403900
ESR2 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17088408 17556531
ESR2 PBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
NR1H4 ABCC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22291955 21296199
NR1H4 UGT2B4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12806625
NR1H4 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16682417 21476904
SP3 EAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18588995
ARNT UGT1A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20854796 9466822
TFCP2 MECP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11865062 15549394 19000991
RUNX2 LGALS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18438928 19020999
TCF7 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16575901 16043491 24692107
SP3 EPHX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315822
SP3 CYP3A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11485307
SP3 SCTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14645499
SP3 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15922656 10884428
SP3 PCYT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12584202 10744779
GATA3 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
ABL1 CRKL â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SIRT1 FOXO3 â—¼   DEACETYLATION ✅ - 0.9 0.9 Signor 24003218
EGFR SOS1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
JAK2 SOCS1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
HNF4A HIF1A â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 12097158 14741200
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
EGFR SHC3 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
BAK1 MCL1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
DNMT1 UBB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EP300 TCF3 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
FOXO3 SIRT1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
GRB2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5220480 7642581
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
E2F1 SP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10850422 10409740 8657141 10547281 8657142
SOS1 EGFR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24797263 16713569 26005835 9447973 23956138 19531499 7510700 20473329 19289468 25754235 18271526 31959764 10675333 8621459
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
GAB1 CRKL â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 25241761 10871282 24728074 30480076 10753869 23397142
SOCS1 JAK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11314018 14517242 14522994 10421843 19287004 29674694 10064597 18508766 9202126 9344848 11971965 11713228 29991678 28258213 10455112
JAK2 STAT5A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
ABL1 CRK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 9747873 11380621 15696159 8875975 9480911 21602891 18835194 18619508 12384576 8194526 11956190 19380743 24412932 9642287 17474147 8978305 12097319 17515907 33961781 12198159 7926767
CRKL CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9162067 9129019 16982329 9590251 8621483 25814554 10907644 10608804 15107835 7545163 9092574 9195915 12244174 18835194 9311917 8524328 16503409 24886428 10657627 14604282 9820532 8662998 9461587 9851874 11399323 9344843 11157475 10204582 9660791 15556646 8978305 11553620 8626543 9988765 33961781 11263968 15358160 11133830
CBL CRK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 9129019 9416834 22974441 8621483 25814554 9178909 15581361 18835194 8943292 12393469 8524328 8683103 8662998 10962563 9461587 19380743 16289966 11792427 8626543 9988765 33961781 9617486 8626404
CDK6 CCND1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15232106 16713569 10022865 24855949 17517622 33854235 11739795 14681455 24953629 11360184 33961781 10580009 17420273 21654808 11160398 9178893 19075005
EGFR EGF â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8145580 21439278
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
EGFR EGF â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16274239 25241761 10085134 11684674 28988771 22729867 18271526 30083275 10788520 23597562 19531499 26280537 8663535 25453753 21822280 12297050 2790960 21439278 12093292 12620237 10970856 18427122 25080504 17697999 9135143 15620700
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5220480 7642581
GAB1 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11314042 22536782 10871282 31980649 10913131 11960376 9804835 9890893 20473329 21706016 33961781 20936779 19380743 9242692 8596638
GAB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25416956 31980649 21706016 10068651 16371368 10391903 32296183 15143164 10913131 19523899 19172738 11782427 19380743 11882361 9660791 16253990 33961781 20936779
CRK GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 8810325 10962563 8662907 19380743 10970810
SOS1 CRK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 31980649 8810325 17474147 8943292 33961781 19380743 32203420
HIF1A ARNT â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 17916562 9159130 24434214 20049704 9704006 11606485 27684187 19168635 11829741 23458834 19845609 16861921 9079689 19251694 11593383 27320910 15850782 15833858 20562859 14764593 12391259 26496610 17197389 8663540 15479785 26160453 14668441 24056783 11025203 28205554 23796364 23363003 20458141 23086815 17213817 21620138 15615775 7836384 15319539 12393189 11782478 15347669 20932347 21512126 10085255 21435239 26350169 15031145 20603618 28628118 20699359 10671489 33961781 34592152 16520375 12810720 16954218 18024476
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
AHR ARNT â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CREBBP KMT2A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
AXIN1 DVL2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ARNT AHR â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8065341 28514442 11768231 9704006 11259609 7488247 19380484 20006590 22138065 11025203 10617682 23477502 9887096 31675361 12024042 12139968 11551916 17392787 18096572 8384309 10619402 7628454 19390533 26350169 8631989 8621524 10671489 33961781 10395741 8619634
MAPKAP1 MTOR â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GAB1 GRB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CREBBP HIF1A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CBL CRKL â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DNMT1 UHRF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CRKL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 23318434 10391235 21188172 25666857 20841568 11278685 23331499 27294865 25893286 21199784 17535448 21051857 10391250 18988627 10391249 28690977 25341038 19788416 26512706 10391251 20195489 12070014 15459660 20057499 15686624 21435002 11223036
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
ABL1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16705159 15923602 15793561 25821558 9111318 15143187 16705160 11593427 20841568
ABL1 RACK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27170279 21124943 20841568 21978545 19423701
ABL1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20651945 29262653 26148237 19075013 20841568 28690977 29348869
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 8978305 22581121 20841568 10837221 18768933 7493940 9710592 16955467 8524328 23331499 21199784 18794134 10592173 21051857 7926767 16443220 18835194 24165979 26500649 18809728 15459660 26192618 24412932 9053848 22286129 8083188 14604282 21435002 9820532 19823681
ABL1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15039778 20841568 8112292
ABL1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21071413 23331499 10753870
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ABL1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10837221 20841568
ABL1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24836440 8940193 20841568
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
MCL1 BAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 20501829 22039431 23430059 23850759
MCL1 BAK1 â—¼   PROTEIN_INTERACTION 4.0 1.0 ACSN 20501829 22039431 23430059 23850759
MCL1 BAK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 20501829 22039431 23430059 23850759
MCL1 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 17145710 18040043 17097560 22516262 26004684 19148187 15077116 19968986 23680104 27818144 15901672 10579309 10837489 21613222 20836993 26186194 17289999 32296183 15637055 26045051 20023629
NKX3-1 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21850191 15705778 24961145 20599703
E2F1 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18660752 12389032 18319725
CASP3 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15014070 15713684 15637055
EGF CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRKL CBL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
GRB2 CBL â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 31980649 8649804 8995445 25036637 23799367 11997436 8943292 9242692 10570290 8662998 11399323 10086340 7642581 9108392 20936779 11133830 8626404 17094785 8063801 9129019 8900205 15210722 8621483 25872741 25814554 9178909 16906159 8950973 17971399 10025673 9295052 19380743 9716598 16713569 11964172 9234717 8083187 7537740 8824292 9259313 9311917 7791764 17072306 14725908 33627783 9461587 9434624 9851874 8695851 12839496 17944804 11792427 10204582 8621719 11823423 9541596 33961781 169092 11263968 98621719 28514442 18273061 7592693 9174058 21706016 8995358 9872323 9233773 9367879 7544353 12941616 10829062 20124286 917890 15677445 9092538 10521482 8647120 19836242
CRKL CBL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
CRKL CBL â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
STAT5A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16155412 18927468 21719533 20372799 23223023 15885880 10064602 23504816 14645506 18024957 19426693
SP1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10497251 22911796 19850937 9236224 17617380 9407106 15870300 22415074 10850422 9584162 10908361 22734486 16267018 9637785 19755513 11410592 11024050 15922873 12794082 20435036 22334592
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
GLI1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19860666 23740243 18524848 23074268
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
PGR CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22396492 22892083 15282324 20479568 22542550
EGR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23872169 20590664 16926376 19850937 11502738 16267018 16547599 9407106
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
TCF3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
TCF7 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
KLF8 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
SP1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9054613 12697671 10446910 18440323
E2F1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21411498 22654424 18818403 11433024 19358274 22207128 16264179 12368233
E2F1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12438307 16931907 14645238
E2F1 UHRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24453336 12838312 15361834 23023523
E2F1 SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16331253 23352642 22372491 24574749 20424123 17471231 23348237 17483325
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12766778 11101847 11988839 14602923 18660752 19188449 18029729 18521084 15210709 11115495 17980704 19363520 12789260 21310950 22952705
CDK6 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCND2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CREBBP E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10753885 15126619 12748276 15123636 8932363
E2F1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15210709 11988839 17488475 11937641
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
PTGS2 EGFR â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18633355 20138012 21847358 23010081 23390297 25987127
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
YBX1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19036157 17595327 24211838 19648825 17875215 16651443
VDR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21458521 16087726 15218361 11967012
EGR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16750517 15863471 23763269 16170359 11830539 17230532
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
PGR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22542550 8347631 16449295 17074804
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
PRKCB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 7805884 17570479 12040186 19568798 15567848 14585353
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
EGFR GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 19901323 15231819 16497976 25402006 17389395 20068231 23066441 11432805 9658397 19509291 18669648 10978177 10753869 10734310 11896055 18271526 24658140 10648629 11779868 31980649 15212693 9890893 17016520
EGFR SHC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 24212772 9507002 16273093 11791173 8760305 8662772
EGFR STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 31980649 10358079 24658140 25402006 18586824 16729043
EGFR CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 23397142 18271526 24658140 25402006 16729043
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
EGFR SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9544989 19531499 9447973 16713569 12577067
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
EGR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20414733 18798221 15635605 15225550
EP300 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057991 17395887 17237818 12471036
AKT2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17964260 16926151
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 14726487 15509516 9989503 9773981 26504087
HIF1A FOXO3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
FOXO3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24062311 16807346 16809346 17575143
FOXO3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23525956 20816089 15604409 23262029
MAPK1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18204439 29445193 22128155 10102273
CSNK1A1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20110348 19188143
PIM1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15837797 21777391 33408118 26376801 10102273 18593906
AKT2 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 19951971 19216069 17680028 11756412 17646672 20214616 11463845 20452955 9829964 20398329 10102273 18593906 16680151 10217147 19188143
SIRT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 24003218 14976264 14980222 15126506 21713995 15917664
FOXO3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11435445 15367686 16807346 18312651
STAT5A GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
GRB2 GAB1 â—¼   PHYSICAL_INTERACTION 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
GRB2 CRKL â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 BRAF â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SOS1 GRB2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 16520382 31980649 32062451 8493579 21988832 14679214 7510700 7514169 21706016 10319320 32203420 9872323 9797459 34407391 16906159 10716926 12577067 8810325 7629168 11960376 7664271 8626525 15192046 7629138 11997436 8943292 10207103 8695800 10570290 10025673 8112292 11726515 8816480 20473329 7559490 7773779 9447984 19380743 7642581 7527391 9716598 9344843 10477741 16713569 19323566 7516467 17474147 9569023 8188688 16893902 11964172 9478994 33961781 8479541 28166272 9009162
GRB2 GAB1 â—¼   SHARES_COMPLEX 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
GRB2 CRKL â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 BRAF â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
GRB2 GAB1 â—¼   ENZYMATIC_REACTION ✅ 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
EGF GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17081983 19531499 17673906 10973965
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
GRB2 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 12766170 21706016 9242692 10913131 11445578 22536782 8596638 11027663 10592173 20936779 11960376 15010462 19523899 20005866 19380743 10871282 9804835 14685170 11314042
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
HIPK2 MECP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19820693 27689990 28835516 22500635 27213019 27941951 25568644
ETS2 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 8552081 10358095 20534573 11782450 15572696
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9804779 25241761 18775330 10194762 8226933 10996427 9604935 8388392 12091337
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK1 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 8702648 17173941 18202149 10628747 15798179 17717077 12529413 15212693 10655479 11110801
MAPK1 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12223490 18220336 15241487 25324174 16543145 18676833
MAPK1 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20058876 15253667 25162926 27049728 18669648 17209041 18088087 20068231 11604491 23602949 18701649 23678047 28554535 19415658
MAPK1 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16046550 17015473
MAPK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10197981 8816480 9922370 8626428
MAPK1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16954218 10551817 18519666 18687685 26784107
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 14654779 21478863 19541618 16508002 19710016 19933846 15664191 29335436 8621729
MAPK1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12008033 15356145
MAPK1 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12008033 26538579 15379552 10593929
MAPK1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10187842
MAPK1 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 14592976 12810726
ETS2 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 8552081 10358095 20534573 11782450 15572696
MAPK3 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9804779 20508164 23331499 24263804 18775330 10194762 12407017 8226933 17502367 34188118 9604935 18988627 31932645 8388392 12091337
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10551817 18519666 24099156
MAPK3 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12008033 15356145
MAPK3 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12529413 10655479 10628747
MAPK3 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15241487 21507240 25324174 16543145 18676833
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK3 ETV6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12435397 15060146 18022807
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
MAPK3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27687725 19264160 29057206 25867060 19801668 25122769 21965325 25187572
MAPK3 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10187842
MAPK3 TCF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 14592976
MAPK3 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 7478566 23331499 8816480 7739560 17570479 9922370
MAPK3 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12008033 15379552
SP1 MCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22406829 18599869 17198743 22734486 18208354 23877711
BMF MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16697956 11546872
CSNK1A1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23028042 33667384 31462704 16511560 29793495 16024788 27114532
MTOR MAPKAP1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR MAPKAP1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20338882 17517883 18372248 19203586 27418134 17277771 15718470 26491696
MYC AXIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC AXIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
PGR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8701093 9408078 22396492 9305935 22892083 10651641
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18586674 12695333
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
MYC WNT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19609274 22710352 17485441 20945354 19149881
MYC TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 76.0 1.0 Omnipath 16287840 15655249 12821782 16880523 21807113 19047367 14744757 16489011 12941894 10786671 14519204 19360348 10723141 12970752 15595642 18365874 15665468 22207128 14611815 10022128 15226182 11274400 10491298 11606399 17070091 19787269 19806010 20454512 19762557 21132266 21553143 18818322 10914736 17934056 19148473 11435602 12695333 12802280 21995449 11287602 12044867 21627565 23860446 17942561 19649288 23759068 10606235 12807729 15958520 17141225 20723213 16402390 16785237 18093727 21855630 24705139 18367227 14563552 16205635 19003324 9988278 17706770 17967894 18226852 18754863 10637317 18586674 14612409 19912441 15371341 11916966 12646176 11279234 18158869
MYC SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24259667 12963825 12769844 23792459 21245140 24177224 23277542
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
TCF3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
TCF7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
SKP2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17145710 24259667 12963825 12769844 17157259 23277542 20852628 16376880 35260179 26038816
PIM1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25749412 28505071 25280219 27775704 18438430 29472550
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MAPK7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22046506 9461566
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
SSRP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15171726 23810005 1406642 19946334
SSRP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18218727 10722927 17725714 12437983 8774705 16489119
ETS2 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18586674 14611815 21763315 17986575
SP1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 24074563 19843528 19047367 15951564 10778946 21536653 19287963 12019268 11452025 19360348 18365874 14577922 19318640 14611815 12368233 15226182 15656906 21553143 15067344 21132266 11342218 16452190 21590772 19649288 17141225 12151407 16234237 17325661 18093727 19106100 18754863 1236823 10637317 21693539 22554713 19912441 11279234
TP73 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15734740 22496369 16234237 16205639
SP3 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11342218 16452190 12151407 19047367 15951564 17548428 11279234
ESR1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21411498 12122114 21693539 18519947 16690106 10805720 19360348 23409030 18754863
ESR2 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12122114 10805720
HIF1A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18754863 15048086 17699105 16961934
SRC TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12808100 20211239 24413564 26908447 18829466
HIF1A TNF â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 10754326 10804084 10952726 11875494 12907458 14660645 15465827 15644117 16110315 16127144 16878026 17404308 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 23390297 24006507 25043024 25103413 25732824 7594497
IL6 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK2 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
PPARA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11009565 17463321 17260462 15669179 19039651 10377130 19640904 19576184 15891579 19225884
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
DNMT1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21765477 24875904 23335796 22742857
SP3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14555463 12759366 19109523 11390427 11500175
AHR TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11470802 17588258 25690886 19703987 15627257 20181658
HIF1A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21386799 17451682 15604270 17548584 17884817 15925386 22320863 23359428 23085511 19766100 16007254 12479793
EGR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 24337575 20653771 12509451 18675783 21841136 20332214 8773576 14767560 23872552 14722058 11856733 11739517 15640148 12560487 11997234 17537727 7918637 9407088 18157146 23632636 16317093 15659537 18651635 11520792 10913190 10419778 23184950
HR TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11490006 10933163 12724409 14638848
UHRF1 TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10646863 12530060
PRKCB TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19007248 12569090 19691289 17081983 8939955 96081879 18691976 9804834 7499337 11940573 15212693
TP63 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16462763 22521434 17716971 19622632
EGR1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17822668 16990849 10574463
TP73 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648616 21245298 11172610 10435630
UHRF1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19798101 22064703 20210320 17673620 24368767 19800870 27049577 20613874 21268065 24782312 26065575 17934516 21045206 21745816 19308066 27045799
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
CDK6 RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18261462 20478528 25241761 17023045 16046550 17431401 17015473 21059642 15475366 22531928
SRC JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8081883 14517306 23911551
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
GAB1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10753869 25241761 24728074 31585087 10871282 10592173 23397142
CRKL GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10753869 25241761 24728074 31585087 10871282 10592173 23397142
ETV6 STAT5A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 31066629 17764812 19345670 23168613
ETV6 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19345670 23168613 27795560 31066629 17764812
SRC RACK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 21685945 12400005 23652203 22174419 16849317 9584165 11279199 17574549 16189514 21978545 21677780 22523568 18596232
CRK GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 24728074 20619534 12138161 19380743 11146548 10592173 19350053 16713569 10618718
JAK2 IL6 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK2 IL6 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
SRC JAK2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
JAK2 IL6 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK2 TIMP3 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20856220 21115385 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
SOCS1 JAK2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10485906 12193701 12223527 12811837 21469115 23124025
STAT5A JAK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10882725 7744007 21719533 19036881 9343435 9698919 11713228 19638583 16847321
SOCS1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10421843 23331499 21071413 10455112 14522994 10064597 28258213 19287004 18508766 11314018 18988627 11971965 11713228 10975987 9202126 9344848
JAK2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18644434 21183952
JAK2 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17081983 34197875 7925280 16497976 15795318 18083107 17389395 23331499 15504549 19534553 9047382 21071413 11641791 18988627 8617237 18250158 19088846 15256422 12529425 28676702 11413148 17016520 9575217
HIF1A IL6 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10804084 15749903 16110315 16127144 16243976 16413922 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 9743347
HIF1A IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17548584 20003295 21258402 15913932 18791496
EGR1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18281687 24453276 23632636 15517885 23184950
NR1H4 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19028791 18981289 19118524 19864602
KLF8 AXIN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
AXIN1 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 WNT3A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 FRAT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
KLF8 AXIN1 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
AXIN1 FRAT1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 10428961 16288291 16940750 19751508 22270359 8666229
KLF8 AXIN1 â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
DVL2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10329628 10829020 21245303 23892894 16713569 17529994
CSNK1A1 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11487578 11955436 11884395 12554650 8638126 19244247 15327768 10581160 10421629 12051714 17318175
ARNT CREBBP â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 11959990 11063749 7836384 11959977 9632793 17804822 9822602 10202154
HIF1A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12542982 20547241 17452336 15907483 19489936 15342390 15184875
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
SKP2 CDC25B â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SP1 SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16969077 16883603 19329185
PIM1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23226679 23807222 20663873 28446188
DVL2 WNT11 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
DVL2 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
DVL2 WNT3A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
PRKCB DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
WNT11 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10862746 20006983 17433286 23396967 15143170 15169958 21316585 16495441 20940229 23140633
WNT3A FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT3 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10557084
WNT3A FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21078818 10557084 11029007 10601008
WNT2 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10557084
WNT7B FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15923619
GLI1 PRKACG â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 17283082 16421275 19056373 16705181
GLI1 MYCN â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257
GLI1 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18813803 19219074 16406505 16880536 21059263 16054035 11001584 17000779 17439715 19190345 8545107 16396903 11274345 20107231
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HIF1A CAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824
HIF1A PGK1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
EGR1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18506761 20448047
HIF1A PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19106818 16397226 21149600 14507857 16818642 23144021
HIF1A ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12067980 20099200 17452336 19128456 17433259
HIF1A PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15794924 19828020 8089148 18024476
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
HIF1A PGK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16585195 8089148 8702901
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
PRKCB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
ESR2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11013076 12095943 12630920 11032808
EGF SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23349873 19481075 15845350 22927910 27462789
SRC SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 9856337
SRC GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26706435 15574420 19881549 12941962 21442024 12808090
SRC HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 22308320
SRC ANXA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 30081903 15302870 24239898 23594883 18083107 2415974 26716413 17389395 27821486 11106497 88296872 16189514 25574848 25303710 2456953 24727000 17287340 2143014 15212693
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
SRC STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11413148 17081983 10358079 22090359 7925280 16189514 15702476 11641791 15212693 8617237
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10391903 12464621 11640929 9885561
RUNX3 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19917777 16034110 23310955 12796513 14500656 24836425 17878336 15034051
GATA3 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 24167278 19542428 23310955 19602726 20696860 24813204 18776904 20706986 20809492 20065998 19801513 21341258
STAT5A GAB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
NR1I2 GADD45B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129222 21127053
ESR1 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11773442 17535799 15033483 22031296 15496458
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
EGR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22198386 22593802 19913601 10395376 18844239 22433566 20472833 24470481
ESR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10894157 15075211 20889718 8770893 19423651
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 CYP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12801909 23376040
SP1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16840740 17616668 17012241 15767339 23635401 10825178
SP1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160217 9339900 19753117
SP1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12554796 12706304 15019994 20087433 10894148
SP1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20427719 18044710 9282327 8349585 10826704 10082539 12637574
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
SP1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18234965 7565762 10411657 23133566 10860921 9458366 17363581 7621073 8103518 10644769
SP1 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12464626 16464174 19064501 16760259 21600882 19303862 11841999 17540780
SP1 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9778040 16410262 21569840 20478378
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 PCYT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10216289 12794070 16484221 20096375 10744779 17384411 16157598 15247247
SP1 SCTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23168245 14645499
SP1 UGT1A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15933209
SP1 TNXB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10631113 18588874
SP1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14567977 22815527 21123453 14645238
EGR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15517885 20624458 20546888 17032742
EGR1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7565762 10392899 10860921 11488907 23478574 11734301
EGR1 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21600882 16464174 21537610
ETV4 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11901151 24983502 21150337 11274170
PPARA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11840453 12388637 11971025 18648741 11578780 11412039 11007963 20022932 21323895
SP3 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16840740 17616668 10825178 17012241
STAT5A PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9551919 21617857 10433370 16585602
AHR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18001219 12548657 15213229 19056653
RUNX3 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17488194 15688019 19403666
STAT5A CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11160217 12586844 14660677 15509806 22723377
TCF7 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
PHB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15140878 17932104 26052702 10938099 12943695
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
STAT5A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11731618 22201800 11682624 11682625
ESR1 PBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19376833 18414489
ESR1 CYP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16010691 17511620 15126349 22761658 18414489
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
ESR1 UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10854430 23714156 9773976 12114525
AKT2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11139588 11432835 11507039 9528769 7838153
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
CSNK1A1 LGALS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8253806 15121858 10961987
HNF4A CYP2D6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8810289 1324931 24318876 11752221
HNF4A CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19077665 20926756 21952236 14742674 17764444 15698577 17344340 12514743 16455805 19934400
HNF4A NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12774017 15331348 12601364 18305375
HNF4A WNT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10549281 20019092 22517624 16809766 22767186 19149881 15695365
HNF4A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 23626788 23038264 17920062 10627496 17603092 21963511 15933209 9013589 16488887 16492670 9799805 15331348 17660447 16049268 11402042 17636037 15322103 16323215
HNF4A PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11981036 15912134 19933841 17022998
ESR2 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16293641 12761896 11014241 19001520 9717846
AHR UGT1A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9466822 9762354 19525444 8068691 11368516 19831498
AHR CYP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17012224 9478971 19287966 17709388 23275542 21742528 12801909 19376845 17511620 19805408 12376470 12859982 18059014 17785579 14728982 19789301 16115918 10051545 21703235 24299737 22138065 22187486 19126602 12213569
ARNT AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8621524 8384309 9887096 20006590 10395741 18096572 12024042 7628454 9704006 19380484 17823304 11259609 19390533 22138065 8631989 8619634 8065341 11768231 7488247
PPARA ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16530456 17026988 12595494 20606297 20346718 19201410 18498712 18758514
PPARA SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12763030 16530456 16584836 12511553 10821819
PPARA CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10744771 11042130 10777541 17660447 14960721
NR1H4 ABCB11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18270374 15471871 16819395 17135343 12135489 16371446 23546875 22345554 11387316 18668687 19833092 12052824 11870371
NR1I2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 18805405 17526937 15499176 18299335 20538721 15367577 18096673 12542705 15269186 10935643 18784074 11329060 12417264 16013442 11602528 19171678 16455805 19077665 19934400 23732298 23807564 23928187 23891548 21920351 17293382 11991950 9727070 15180306 15698577 17764444 21292004 11602521 11336976 12781341 12606758 10403778 12167569 19712670 12664659 22982774 21311750 20736322 16219912 21342487 21733184 19129222 19138736 19232333 23179081 22976785 19686701 15650019 11581012 23536728 12130689 12601364 15523048 16608838 17035600 12072427 17429319 10570062 18332045 12851153 10772626 11114890 20171174 15100175 12514743 10611146 20942813 19074998 18540626
NR1I2 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21733184 24498169 11836020 11706036
NR1I2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15629111 15322103 15331348
ARNT CYP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24299737 12801909 19376845 19287966 16115918 10051545 19255421 21742528 12376470
PRKCB MARCKS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17081983 20166139 18767875 17322306 11162562 19413330 19664995 18578522 91317794 20068231 11930178 16116087 18669648 8557118 17287340 8422248 19651622 20058876 18707149 7588787 18212344
VDR CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22939842 11991950 18400206 11723248 19712670 12167569 19581388 15358113 12147248 15205382
VDR CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19106115 17054913 20371703
SP3 SLC9A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12464626 16464174 16760259 19303862 17344314 19064501 17540780
STAT5A PIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14695224 16146838 11564778 15498859
WNT7A FZD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15705594
WNT2 FZD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 12138115 19038973