Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDC37 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
MAVS IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
TRAF2 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF3 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IRF3 TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
IRF3 TBK1 â—¼   COLOCALIZATION 2.0 0.8 intact 17599067 5220070
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAVS CYLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
TBK1 CYLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
DDX3X TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
TRAF2 TRAF3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
IKKE IRF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19153231 34079066
MAVS CYLD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18636086 30410068
CYLD DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27591049 31762063
HSP7C MAVS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IKKE PSDE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 32476569
IKKE PSB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 30682859
HS90A TPM3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 16263121
MYL6 MYH10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
TM173 IRF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25636800 30018345 33086059 24622840
TRAF2 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
IKKE TRAF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22079989 19380580 26519536 23308279 27980081 34084167 29125880 29920243 32656094 24763515
TBK1 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939624 14743216
TM173 IKKE â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22312431 19433799 28346439
IKKE HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939624 14743216
IRF3 HS90A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20628368 16394098
TRAF2 TRAF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9718306 30561431 15383523 21903422
CLH1 HSP7C â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 29568061
CYLD TRAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27591049 12917691 23405219 28900035
MAVS IKKE â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19153231 21200404 29125880 16177806 19380491 32511263 24706939 21903422
IKKE TCPE â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 25852190
IKKE HSP7C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TPM3 IKKE â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 14743216
IKKE RUVB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 14743216
HS90A IKKE â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939624 14743216
IKKE ML12A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 14743216
IKKE MYL6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 14743216
IKKE CALM â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 14743216
IRF3 MAVS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16153868 22908223 25636800 24379373 21903422
TBK1 TM173 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21903422 19416887 32678307 21074459 28346439 29899553 33086059 30943264 33767426 31534043 28763789 33139700 19433799 32383759 23542348 22745133 24622840 18724357
MAVS DDX3X â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20127681 27980081
IKKE TBKB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21931555 17568778 21903422
TANK TRAF3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MAVS TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
IRF3 MAVS â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
IRF7 IRF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18641315 11162841
IKKE MYH10 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 14743216
IKKE CYLD â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18636086 23453969 29755980
TBK1 CYLD â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18636086 25923723 29755980
HS90A TBK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22939624 14743216 16394098 20628368
TBK1 IKKE â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25939384 31534043 17599067 32298923 29251827 30420664 21903422
TBK1 MAVS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23028469 16153868 32366851 28346439 21813773 29125880 32511263 24643253 25636800 33372174 21903422 29743353
MAVS TM173 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19416887 20080758 22908223 22000020 22312431 22911572 23542348 24622840 18724357
DDX3X IKKE â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20657822 27980081 18636090
IKKE CLH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 14743216
RUVB1 HSP7C â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27684187 17643375
MAVS TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
IKKE TRAF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 20449947 23453969 29125880 23007157 33961781 25852190
MAVS TRAF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 27348524 16153868 31806368 30527812 29125880 33582548 32877691 26221961 21516116 31390091 30561431 21903422
TRAF3 TBK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22330071 32324863 29125880 27135603 22792062 23986588 20174559 22079989 22908223 33608556 28049150 32779804 24763515 33372174 24622840 23717208 19380580 23308279 34084167 17991829 29920243 33187908 26928339 33411856 31404116
HS90B HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25864199 29930177 26344197
TANK TRAF2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
IKKE CDC37 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 14743216 25036637 21903422
IRF3 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20483755 15367631 15664995
MAVS IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950 16153868
MAVS TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
IKKE TANK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21931555 17568778 23007157 21212807 25852190 33961781 10759890 17823124
TANK TRAF3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22079989 14743216 26779844 19380580 14517219 34084167 12005438 33961781 8710854 17823124 30561431 21903422
IRF3 IKKE â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12692549 15695821 19380580 28346439 19153231 18636086 27622505 32656094 22072751
IRF3 TBK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23028469 31534043 25636800 16394098 30267576 21903422 22079989 15695821 32241891 20628368 18636086 15841462 19380580 28346439 18583960 25803835 17599067 12692549 19153231 22388039 24807708 19656901 22072751
IRF3 TBK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843640 20304918 18636086
TRAF3 MAVS â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
HSP7C HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27708256 16189514 25864199 22504172 26344197 9269769 21360678 20039095 19875381
IRF3 TBK1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
TBK1 TANK â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5220020 17568778
TBK1 IRF3 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 17599067 5220070
TBK1 IRF3 â—¼   PHOSPHORYLATION ✅ 0.92 0.92 mint 6948053 18583960
TBK1 IRF3 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 17599067 5220070
PSB1 PSDE â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 17323924 22939629 27428775 28821611
MAVS TRAF3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
TBK1 TRAF3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TRAF3 MAVS â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 27348524 27980081 32366851 32324863 29125880 22792062 22022264 30267576 22079989 31806368 20080758 21200404 22908223 30527812 33608556 31390091 26221961 24622840 16858409 33582548 19419966 22901541 32511263 19893624 26519536 23545497 33411856
TBK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 14743216 32707033 20449947 20562859 29125880 23007157 27135603 30420664 33961781 10990461 30561431 21903422 32041822
TANK TBK1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDC37 HS90B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25036637 28215707 24189400 23428871 26496610 22939624 33961781 27339980 11036079 25486457
CDC37 HS90A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 24292678 24462205 22939624 14718169 15647277 16335536 21871133 25036637 26496610 21745565 25486457 12176997 22729780 24189400 22504172 22315411 26804907 11413142 12930845 20159553 15001580 19875381 27353360 9685350 33961781 16611982 21360678
TBK1 TANK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21931555 16189514 31114588 21988832 30420664 21903422 14743216 10581243 29395067 30561431 23286385 27035970 25409927 17823124 32707033 17568778 24488098 23007157 33961781 18307994 29251827
TANK TRAF2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 14743216 16189514 16713569 21988832 20562859 10581243 23007157 12005438 33961781 8710854 10759890 28155233 30561431 21903422
TBK1 TBKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21931555 14743216 17568778 29395067 27035970 30420664 32707033 21903422 23286385
HS90A HS90B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 25036637 31536960 20353823 26496610 22863883 26344197 33961781 21360678 19875381
TANK IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
TRAF3 IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
TBK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 17599067 9786932 15210742 22787218 26712804 16127453 12702806 15367631 12692549 16380379 17706453 16199137 16914100
MYH10 MYL6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
TANK TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20562859 21988832 21903422 8710854 12005438 14743216 10581243 16713569 23007157 10759890
TANK TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16127453 17568778 27035970 25409927 23286385 18307994 24488098 21419663 21988832 21903422 15210742 14743216 16189514 19820708 21931555 10581243 23007157 17823124 17468758 17327220
TRAF3 IRF3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
MAVS IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17020950 25636800 21903422 16153868 22750291
TBK1 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 24549848 18583960 22072751 16380379 26811330 16127453 17618271 23478265 19153231 12692549 28618271 17599067 22388039 15841462 25636800 21903422 15210742 33990776 20532218 16699525 20170763 30842273 12702806 16306043 17018283 20628368 16914100 33411856 23746807 28159912 16394098 18356163 22904301 34379517 22810896 14703513 22750291 27548204 29800227 22079989 24056301 14679297 17706453 20511230 24396068 19211767 18440553 16281057 12524442 16625202 9463386 19893624 18636086 15749911 18818105 27125670 24807708 15695821 9566918 30496178 17526488 19656901 23028469 32351706 24371060 15367631 16199137 25803835 24622840 16155125
CYLD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12917691 23405219 17851586
TRAF3 TBK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12692549 15210742 16306936 16281057 14530355 17526488 17047224 14703513 23453971
MAVS TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22901541 19893624 17020950 18818105 21200404 16306936 18207245 19546225 22844514 22792062 19193783 34610835 16858409
TRAF3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 27135603 15210743 16127453 15210742 16306936 12702806 23986588 22792062 16177806 20389019 17991829 20174559 16858409 23717208 34084167 22330071 17468758 17327220 24622840
MAVS TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 21813773 15210743 16127453 33372174 17020950 25636800 21903422 15210742 16753195 16306936 12702806 24643253 16177806 27419230 16153868 16858409 29743353 17468758 17327220