Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FMR1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17592139
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
KALRN COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
LNX1 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
COIL KALRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
KALRN RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9139723 21483438
GNA11 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA15 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNA11 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA11 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
KALRN GFI1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
GNA14 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
MYC CDC5L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CDC5L KALRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 17043677
CDC5L DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
EFNB2 EFNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KALRN NDEL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
KALRN DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
GNA11 GNB1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
RAC1 KALRN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9139723 21483438
DISC1 NDEL1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MAPKAPK5 MAPK6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 21900206 2001699 8089645
GFI1B MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19522008
MAPK6 SPTAN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KALRN MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12546821 22508986 18031682
MAPKAPK5 KALRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22508986
KALRN MAPKAPK5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12546821 22508986 18031682
MAPK6 MAPKAPK5 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
NDEL1 DISC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 20880836 12812986 29961565 90000000 12506198 14962739 33961781 31413325 17043677
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
PAK1 RAC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 24625804 19327867 15143066 9535855 17245428 11134022 15673687 15289329 16492808 16551621 21029865 16678097 19596003 26175416 17389360 31871319 24056087 25843002 25150978 12879077 15212766 19693014 11030651 16630611 20810653 8107774 11130076 25468898 29615491 19732720 19270716 21474670 10706722 19277120 10802735 21167153 24172987 21454543 15548653 16002993 12650940 18426980 19961560 11950930 24792722 15688026 7744004 20936779 25819133 15075243 22581261
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MYC FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14563113 20101459 20155283 12655294 14519204 10734130 11050389 15302589
PAK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21372320 21177870 18720373 21317288 18248330 17161475
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
DISC1 NDEL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 12812986 17043677 12506198 31413325 20880836 29961565 14962739 17202468