Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDC37 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KTN1 DCLRE1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EGFR RAB7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
FKBP5 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NR3C1 FKBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18524780 12519866
HSP90AA1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KTN1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ATF4 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATF4 DDR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20564243
KTN1 KIF5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10913441 15316074
HRAS NDEL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS FAM184A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KTN1 EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAC1 KLC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
RAC1 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31871319 8769096
RAC1 KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
RAC1 KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
RAC1 KTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8769096
RHOA KLC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
RHOA KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
RHOA KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
LRRK2 FAM184A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 KLC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
MYO9A CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDC42 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31871319 8769096
CDC42 KLC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KTN1 AKAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RHOG KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
KIF5A KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
RHOG KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
KLC1 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
HNRNPA1L2 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BCAP31 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SLC16A7 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CENPE KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 FAM184A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 KLC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
KTN1 AKAP17A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 SPATA9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 NEUROD6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 MYO9A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KTN1 PHRF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RHOG KLC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
HNRNPA1L2 TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ADRM1 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
CDR2 NEUL4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
YIPF3 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAC1 RAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LRRK2 RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 21454543
LRRK2 EF1G â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 ADRM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24947832
LRRK2 EF1D â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24947832
RAB7A CDC42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 31871319
BMI1 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 EF1G â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
BAP31 RAB7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31588230
RAB7A RHOG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26496610
DTBP1 KLC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RAC2 RAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NDEL1 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SPC25 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
NEUL4 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22261722 29426014
BAP31 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 30021884
VTNC KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CAN1 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LPAR1 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
EF1G KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RTN4 KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
F134C KTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
F134C RTN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MMGT1 BAP31 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27342126
HSP90AB1 NR3C1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
KIF5A KLC2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CDC37 FKBP5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
PSD7 CDR2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MMGT1 EMC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32439656 22119785 26496610 27342126 33961781 26186194
RHOC RHOA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781 31980649
RHOA MYO9A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 32203420
KTN1 CDC42 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9535835 31871319
CDC42 MYO9A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 21311754 20936779 16169070
SYNE4 KIF5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DTBP1 KIF5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SYNE4 KLC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DTBP1 ABI1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DTBP1 KTN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DTBP1 KLC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SYNE4 KLC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LPAR1 F134C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
KTN1 RHOA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8769096 12773565 31871319 11162552 11689693
LRRK2 CDC42 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
CDR2 KIF5B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
RAC1 LRRK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 21454543
KIF5B MEOX2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
LRRK2 CDC37 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18367605 22612223 20642453 26355680 16321986 23075850
EGFR EF1G â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20029029 31980649 28065597
ESR1 FKBP5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27483141 9222609
CDR2 KTN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27173435
CQ059 NDEL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194
PSD7 KTN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19615732 26186194 33961781
CQ059 KTN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
DTBP1 CQ059 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
KLC1 KLC2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDC37 LRRK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
RAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16331275 21217774
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR CDC37 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 12471035 24189400 23956138
EGFR ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
PSD7 ADRM1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24811749 28514442 22863883 33961781 26186194 19615732
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
NRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
PKN2 RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31871319 9121475 33961781 9446575 8910519
KLC1 KIF5A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 3130248 1607388 3134048
KTN1 EF1D â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33029523 33961781 12773547
KTN1 RHOG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31871319 11162552 11689693
KIF5B KLC2 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
HSP90AA1 NR3C1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
KIF5A KLC1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
KIF5B KLC1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
KLC2 KIF5A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10491391 22939629
KLC1 KLC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 26496610 22863883 33961781 17332754 22939629
EF1G EF1D â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 19293945 25416956 32814053 22863883 33961781 26186194 16169070 30021884 9407120 26344197
EMC2 MMGT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ADRM1 PSMA1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KLC1 KIF5A â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 10491391 33961781 9624122 22939629 26344197
ADRM1 PSMD7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMD7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
HSP90AA1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 16131566 8089152 10903152 26804907 31467278 8645634 15916966 24949977 21511880 19875381 9334248 12093808 16189514 20195357 24462205 10066374 14987994 8898375 8621522 8139547
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
EIF2S2 ATF4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
RHOA KTN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7787244 11933159 8769096 9822636 8912005 11689693
RHOA PKN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18835241 9446575 9121475 8910519
RHOA KTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12773565 11689693 8769096 11162552
LRRK2 SNAPIN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23949442
RHOC PKN2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14514689 21351730 10619026 9988689 18006505 24128008
RHOG KTN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7787244 11933159 8769096 9822636 8912005 11689693