Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LMNA EMD â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 30488537
EMD ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0020231 15328537
SMAD9 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LMNB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
LMNB1 LMNA â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SMAD9 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15231748
LMNA PDCD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
H3C2 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19766566 8009287
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 CKB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17272396 10411295
RYBP LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H1-1 RIPK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMAD9 YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
EMD HDGF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21907836 17620012
SMAD2 SMAD9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15231748 33961781
IPPK LPAR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LPAR1 REEP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
LEMD3 SMAD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SMAD2 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20207742 11555647
EMD ACTB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 17620012 12670476 15328537
LEMD3 RABAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
LEMD3 SMAD9 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
EMD LMNB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 17620012 12670476
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
SMAD3 SMAD9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15231748 33961781 26186194
SMAD3 SMAD9 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMAD2 SMAD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9111321 28628118 18729074 28205554
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FOXH1 SMAD2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
LMNA LMNB1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
EMD LMNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22412018 16189514 25948554 21346760 11587540 12755701 10673356 29568061 17620012 12670476 11313760 34079125 11173535 24927568 30488537 14597414
PRKCB EMD â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 22986494 8463284 8034666
LMNB1 LMNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22412018 16189514 19727227 21346760 25948554 24623722 21988832 31467278 26264872 29997244 32814053 33961781 34079125 30021884 30419336 26524528 29568061 11792809
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
ESR1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
LMNA PRKCB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 22986494 8463284 8034666
LEMD3 SMAD2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
LEMD3 SMAD1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FOXH1 SMAD3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32296183 9858566 21828274 15750622
FOXH1 SMAD2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9389648 9858566 11371641 32296183 10199400 12732634 10938097 16916642 9702198 21828274 15750622 9288972
EMD LMNA â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
FOXH1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9389648 23331499 21828274 9858566 9288972 16916642 10199400 10938097 12191473 15750622 32296183 12374795 11371641 9702198 12732634
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
PRKCB ILF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18097023 20870937