Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HDAC3 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
CCND1 RBL2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
NCOA2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21505052 22581837
NR0B2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18537191 12571228
H1-1 CDK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EP300 COPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8414198 23441852
EP300 COPS2 â—¼   ACETYLATION ✅ 2.0 0.8 intact 8414198 23441852
EMD ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0020231 15328537
SUMO3 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7941484 19680224
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EP300 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12371907 11796223
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
TP53 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8200620 21821029
UBE2I HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GRM1 KPNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19084525 6979076
LIG3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
F2R MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
MAPK3 PARP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
TP53 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
NCOA6 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
SUMO3 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
SUMO1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
PRKDC H1-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18250087
TDG SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218717 16763556
SUMO1 MEF2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
SUV39H1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
TDG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
TRIM24 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0813177106 19556538
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
TP53 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18812399 8008642
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 P2RX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 SCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 ABCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10783169
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
CREB1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721872 12658356
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
UBE2I NMI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
RARA SCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11397803
NR0B2 HDAC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
YWHAE NCOR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8007916 17630505
NCOR1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934400 12072427
NR0B2 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18385139 16213225
MED4 CDK8 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 25281560
MED21 CDK8 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
NCOA2 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 10454563
YWHAQ PDPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12177059 5215652
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
POU2F1 TXNRD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11375392
NR3C1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16303956 3611064
CREB1 HLA-DQB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1324879
CREB1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23466342 21054339
CREB1 ADCYAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16006741 24018543
CREB1 NTRK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15234351 17553693
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
NCOR2 TBL1XR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15601853 14980219
RBL2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15467457 8204372
PPP2CA RBL2 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 15467457 8204372
PPP2CA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10644691 19061640
RXRB RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12767074 1310351
RARB CYP26A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16261163 16012519
NR0B2 RARB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11368516
NCOA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
RARA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10607566 23331499
RARA MED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17641689 5220098
RXRB RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RARA ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22353356 19752193
RARA UCP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22561685 10600643
RARA HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20724538 10766818
NCOA3 SRA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 11358796
NCOR2 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17456789 20137375
NCOR2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934400 12072427
SAP30 GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR3C1 MED25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17641689 5220098
NR3C1 TRIM63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18615595 18612045
NR3C1 RXRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10860926 12573484
NR3C1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18524938 17572486
RXRA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
MED14 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10508170
NR3C1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
NR0B2 GPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
ABCA1 RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18782758 21507939
RXRA ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14527955 24007921
NR0B2 SCT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16888194 19372104
NR0B2 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12198243 22424975
NR0B2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22982774 16455805
NR0B2 THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11368516
NR0B2 ESRRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11705994
THRA MED17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14576168 5216777
HR MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23684955 22314224
ELP1 TAC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GATA2 P2RX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
PENK OPRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082510 32196115
KCNE1 KCNQ4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16301825
H1-1 THRAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NCOA3 RXRA â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
MED6 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16204234 15808511
PARP1 RARA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19377461 25303530 15808511
RARA MED25 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17641689
GPS2 NCOR1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
MED12 MED24 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
EMD HDGF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21907836 17620012
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
MED21 SRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GPS2 CREB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
MED25 MED13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14657022 29568061
MED13 MED31 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 29568061
NCOA3 NCOA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18267973 11971985
NCOR2 RXRA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 9415406 9878542 12665583 15604093 10082574
TKT MED17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MED6 MED16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED27 MED16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
LPAR3 SLC16A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
MED1 MED31 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
MED12 MED25 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 20133760 26496610 33961781
MED12 MED31 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 20133760 26496610 24981860
MED1 CCNC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 18391015 20098423 33961781 24981860 26186194 20133760
MED21 MED31 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
MED21 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
MED25 MED14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 24882805 25792360
MED14 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 9989412 26344197
MED14 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9989412 18418385 33961781 24981860 22939629 26344197
MED6 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED25 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 14638676 33961781
MED17 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED17 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED21 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
MED24 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED25 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 24882805 25792360
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CCNC MED16 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MED25 MED6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MED16 MED27 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 CUL1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
EP300 ILF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20808282 33742100
EP300 XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15023334 33742100 21988832
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
TAF11 TAF7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14580349 29111974
PCNA XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12171929 11239001 24695737
HDAC3 NR0B2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15835920 17895379
RARA RARB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 22022577 33961781
MED4 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 25281560
MED4 MED10 â—¼   PROXIMITY ✅ 0.84 0.84 mint 25281560
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
KPNA1 LMNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
MED13 MED27 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EP300 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
NCOA6 XRCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10823961 12519782 30585729
HDAC3 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
NCOR2 NCOR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16033423 10944117 11013263
RARB RXRB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 25416956 1331778 20211142 15604093 26871637
RARA NCOA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 9430642 12503607 12612084 9192892 20543827
SAP30 NCOR2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9702189 11013263
MED4 MED31 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 24981860
MED6 MED14 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24981860 9734358 26344197
MED24 RXRA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9653119 16189514
RXRA MED25 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17641689
MED4 AMOT â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 25416956 33961781 25281560
MED16 MED4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED12 MED17 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
NCOA6 RARA â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CCNC MED17 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
EMD ACTB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 17620012 12670476 15328537
EP300 NCOA2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10490106 9920895 15731352 20448036
SUMO1 PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23871147 15576338 19779455 15561718 19596686
PCNA PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20129057 20302655 12930846 21690293 20303835
RARA SUMO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15171703 24819975
SUMO1 SUMO3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 15576338 17938407 21098080
SRC RXRA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17363140 15116119 10517671 15140878
RARA AKT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16417524 23693014
CTNNB1 TBL1X â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
MED13 MED6 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EMD LMNB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 17620012 12670476
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
NCOA6 PRKDC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10823961 12519782
HDGF PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21907836 34079125
TDG RARA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24394593 12874288
XRCC6 ILF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31536960 30585729 21969602
HDAC3 GATA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 11567998
MED12 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 20133760 26344197
MED12 MED6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 27684187 22939629 20133760 26344197
MED12 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 27684187 22939629 20133760 26344197
MED12 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 26496610 23563140 33961781 24981860 27684187 20133760 26344197
MED12 CCNC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 30099503 33961781 24981860 26186194 19047373 20133760
MED12 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760
MED12 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 24981860 22939629 20133760
MED12 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760 26344197
MED13 MED17 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
MED17 MED13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 29568061 26344197 24981860
MED13 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 29568061 26344197
MED13 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 24981860 22939629 29568061 26344197
MED13 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 26344197
MED13 MED6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 26344197
MED13 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 22939629 29568061 26344197
MED1 MED31 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 15989967 24981860
NCOA3 RXRA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9267036 16713569 9346901 15863722 11027271 11851396
RXRA FUS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32814053 9440806 16713569
MED14 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9989412 18418385 24882805 33961781 24981860 22939629 26344197
MED14 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 24882805 24981860 22939629 26344197
MED6 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 24981860 24882805
MED27 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 33961781 24882805 24981860
MED16 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 24981860
MED21 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 24981860
MED16 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24882805 24981860 33961781 22939629 26344197
MED25 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 25792360 24882805 33961781
MED12 MED4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED12 MED27 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED10 MED13 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED13 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED6 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED25 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED27 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CCNC MED10 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED10 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED12 MED16 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED12 MED6 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
GPS2 HDAC3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED12 MED21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED1 MED21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PCNA UBE2I â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED10 MED25 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RXRA THRA â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED16 MED24 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CCNC MED1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED27 MED6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED17 MED27 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RARA RXRB â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED14 MED4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED14 MED16 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED14 MED27 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NCOA6 RXRA â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED13 MED21 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED17 MED6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED21 MED24 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CCNC MED6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MED24 MED4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
EP300 MEF2A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12371907 20590529
AKT1 PRKDC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15678105 15262962
PRKDC ILF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20808282 9442054 21969602
C1QBP KNG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8710908 34804054
CDK8 MED27 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CDK8 MED25 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RARA SRC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17641689 10454579 12612084 20338915 17363140
RXRB RARA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 29892012 16189514 25303530 32296183 16713569 21988832 20211142 15604093 26871637
MED21 MED14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9734358 33961781 24981860 22939629
MED14 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED25 MED6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14983011 14657022 17641689 25792360
MED4 MED6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED27 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED24 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
GPS2 TBL1X â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED1 MED17 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED1 THRA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED1 MED16 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED14 MED24 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MED1 MED24 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MED1 RARA â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MED1 MED12 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CDK8 MED16 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MED12 MED14 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MED10 MED16 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MED17 MED24 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC3 CCND1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15713663 12048199 16461912 20484017 15558026
CD44 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RARA NCOA6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10823961 16713569 10866662 11158331 10567404
MEF2A SUMO1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19684601 17036045 16484498
ESRRA PPARGC1A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CDK8 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 29568061 26496610 33961781 24981860 26186194 23602568 32707033 25281560
CDK8 MED27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 33961781 24981860 26186194 23602568 29568061
MED13 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 29568061 26496610 33961781 24981860 27684187 20133760 26344197
MED4 MED13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12421765 29568061 33961781 24981860 22939629 25281560
MED13 MED21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 24981860 22939629 29568061
MED25 MED1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 14638676 15989967 17641689 20098423 25792360 33961781 14983011 14657022 20133760
MED1 MED21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 24882805 33961781 24981860 22939629
MED1 RXRA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21478865 15863722 9653119 11027271 11438648 10935544
MED1 MED27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 33961781 24981860 22939629 20133760 26344197
NCOA3 RARA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25303530 16713569 17475621 9346901 12665583 19144644 15604093 9192892 20413580 16456540
RARA NR0B2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8650544 16189514 16713569 9773978
NCOR2 GPS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24943844 33961781 26186194 21240272
RXRA TRIM24 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
ILF3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 29884807 16713569 11438536
MED10 MED24 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 17404243 24882805 14576168 33961781 24981860 10882111
MED6 CCNC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10993082 33961781 24981860 26186194
NR0B2 RXRA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12198243 16189514 21988832 10594021
MED21 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24882805 33961781 24981860 22939629 25281560
MED25 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 25281560 14638676
KDR SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MED1 MED10 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MED17 MED21 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK8 MED4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK8 MED17 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED13 MED16 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NCOR2 RARA â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED10 MED27 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED14 MED17 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NCOA3 RARA â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MED16 MED4 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MED10 MED12 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CDK8 MED10 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED1 RXRA â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED1 MED14 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED21 MED4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MED27 MED4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PCNA CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15681588 7908906 8101826 33961781 7903056 21654808
NCOA3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11358796 19095746 15808510
CDX1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15215241 14508520 10660624
EP300 NCOA3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16923966 10655477 9267036 23065768 16227615 20368990 11823864 10490106 25728767 33589584 10866661 15145939
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
NCOA6 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10847592 11158331 10567404 12482968
NCOA6 RXRA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10866662 11158331 10567404 10681503 11773444 14578865
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
XRCC5 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15941674 10750018 20023628 17308091 15758953 20085707 33005030 10446239 26496610 19303849 20711232 9312071 26446488 15520013 28154079 28345663 16857680 12393188 22404984 21679440 26344197
XRCC6 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20711232 21575865 33005030 28345663 15941674 10064605 26496610 26446488 15520013 10750018 8422676 26175416 22939629 17308091 30585729 19303849 21969602
SUMO1 TDG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 10961991 21284855 16763556 16524884 15959518 24637324 11889051 17060459
SUMO3 TDG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16620772 25027693 11889051
TP53 SUMO3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 25218447 21900752
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
PDPK1 XRCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SRC KDR â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
GPS2 HDAC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 17895379 11931768 21258344 33961781 26186194 24943844 16980585
HDAC3 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 10809664 28348241 11931768 10944117 18202150 21258344 16980585
HDAC3 NCOR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12205093 21624135 10809664 24449765 16924111 10944117 21258344 11509652 26728228 15837933 12628926 11804585 22230954 14527417 16980585 23752268 29523594 12502735 10860984 11013263 16481466 17126328
NCOR1 THRA â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
GPS2 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12628926 11931768 33961781 26186194 14527417
NCOR1 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 15601853 22294699 12628926 10809664 27880911 11931768 10944117 18202150
NCOR1 RARA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9531570 19377461 10336495 16606617 25303530 21988832 27107012 9121466 10882117 15604093 16469706 30532072 18978041 15336696 7566114 9486655 20543827
AKT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23940660
ESRRA PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23668787 16213225 21625432
NCOR2 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12502735 12628926 10809664 10944117 21240272
GPS2 TBL1X â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24943844 26070566 11931768 33961781 26186194 21240272
MED12 CDK8 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 30099503
MED21 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 9710619 10024883 9315662 26496610 33961781 24981860 23602568 10198638 11867769 10882111
MED25 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 14638676 26496610 20098423 25792360 26186194 14983011 14657022 29568061
CDK8 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 18418385 15989967 29568061 10024883 26496610 20098423 23322298 33961781 24981860 26186194 23602568 10198638 11867769 10882111
CDK8 MED24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 10024883 26496610 23322298 20098423 33961781 24981860 26186194 23602568 10198638 26344197 11867769 10882111
CDK8 MED31 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10024883 26496610 24981860 23602568 10198638 29568061
CDK8 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 30695077 29568061 19047373 26496610 20098423 23322298 33961781 24981860 26186194 23602568 10198638 11867769 10882111 23746844
CDK8 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 26496610 20098423 33961781 24981860 26186194 23749998 23602568 10198638 11867769 10882111
CDK8 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 30695077 20098423 23322298 19047373 27684187 11867769 20720539 10882111 15175163 30099503 26496610 23602568 29568061 23749998 32707033 23746844 33961781 24981860 26186194 10198638
CDK8 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 18418385 10024883 26496610 20098423 11416138 33961781 24981860 26186194 23602568 10198638 29568061 10882111
CDK8 MED16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 26496610 20098423 33961781 24981860 26186194 23602568 10198638 11867769 10882111
MED1 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 26496610 20098423 23322298 23563140 33961781 24981860 27684187 20133760 26344197
MED10 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 17404243 26496610 14576168 33961781 24981860 26344197 20133760 10882111
MED4 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21293490 26496610 20133760 33961781 24981860 22939629 25281560 26344197
FN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
SRC PPP2CA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
PDPK1 AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9368760 11825911 14500673 10698680 31467278 12149249 27563096 11313365 11278835 22569334 26264872 10226025 32876514 26256536 21775285 11438723 11445557 23397142
AKT1 TKT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24981175 31534226
CREB1 RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
MED10 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 10882111 14576168 33961781 24981860 29568061 26344197
MED1 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 29568061 20098423 23322298 23563140 33961781 24981860 20133760 26344197
THRA RARB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
RARB THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
CTNNB1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15592430 10987283 12154096
RARA MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19377461 25303530 16713569 17641689 21478865 10760302 9653119
MED10 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 15989967 24882805 14576168 33961781 24981860 10882111
MED1 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 24882805 20133760 33961781 24981860 22939629 25281560 26344197
MED1 MED6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 33961781 24981860 22939629 20133760 26344197
MED1 MED24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 9653119 33961781 24981860 22939629 20133760 26344197
MED1 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 33961781 24981860 17967894 20133760 26344197
MED1 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 9989412 18418385 15989967 20098423 33961781 24981860 22939629 20133760 26344197
MED1 MED16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 20098423 33961781 24981860 22939629 17967894 20133760 26344197
RARA NCOR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19377461 9415406 25303530 16713569 17475621 9380707 16219912 15604093 9256429 7566127 11929748 10082574 20543827
RARA MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15246741 10415749 1682056
THRA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
RARA THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
NCOA2 RXRA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15657427 9430642 21478865 24561505 11514567 11851396 11981034 17947383 10748178
NR3C1 RLN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15149733
MED10 MED31 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860
MED10 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 12149480 17404243 24882805 14576168 33961781 24981860 26344197 10882111
MED10 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 15989967 24882805 14576168 33961781 24981860 22939629 25281560 26344197
MED10 MED27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 26344197
MED10 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 26344197 10882111
MED10 MED25 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781
MED10 MED16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 26344197 10882111
RXRA NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23546875 19111018 15202934
POU2F1 PTGIR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19118563
OXT OXTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 4065330 2991279 1313946
TACR3 TAC3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1374246 10866201 17561251
EP300 MEF2A â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CDK8 MED6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
MED4 MED6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CDK8 MED21 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MED1 MED13 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
CDK8 MED24 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
COPS2 CUL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
UBE2N UBA1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 31638574 14517261 18678647 25527291 27173435 30097011 33619271 27182664 29537486
CCNC MED12 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MED10 MED17 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MED13 MED14 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CDK8 MED1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CCNC MED13 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 28514442 33961781 24981860 26186194 19047373 29568061
RARB RXRA â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 15528208 22022577 7565739
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
CDK8 MED14 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MED10 MED4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PPARGC1A ESRRA â—¼   UP_REGULATES ✅ + 0.93 0.93 Signor 18074631
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
AKT1 PDPK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MED10 CCNC â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 15175163 17404243 33961781 24981860 26186194 10882111
MED6 MED17 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 26344197 33961781 24882805 24981860
MED17 MED21 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 24981860
CCND1 RB1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
KPNA1 KPNB1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
PCNA SUMO1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 21167178 22457066 22153967
NCOR2 HDAC3 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24449765
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
MED21 MED6 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 9734358 33961781 24981860 22939629
MED4 MED17 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 25281560 26344197 24981860
MED14 MED31 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
MED31 MED6 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
RARB RXRA â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
NCOR2 RXRA â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CREB1 EP300 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12665587 21268077 10506141 21212407 11313407 7870179 17476304 22787115 26944191 33846793
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
SAP30 NCOR1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9702189 16713569 11013263
CCNC MED13 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
MED10 MED21 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 15175163 24882805 14576168 33961781 24981860 10882111
NCOR2 TBL1X â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
NCOA2 RARA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
HDAC3 NCOR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16917504 11466315 10944117 21258344 11509652 16195251 16469706 14722073 15601853 12628926 11931768 11804585 14527417 16980585 23752268 29523594 16713569 10860984 11013263
MED10 CDK8 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 15175163 15989967 29568061 10024883 26496610 33961781 24981860 26186194 23602568 10198638 11867769
MED6 CDK8 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32707033 29568061 10198638 10024883 15808511 26496610 11416138 33961781 24981860 26186194 23602568 14983011 26344197 11867769 10882111
RARA RXRA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 9415406 25241761 21988832 16540467 15604093 1310351 10698945 14521715 12052862 9582446 19345331 31700049 7760852 15528208 21478865 9121466 10882070 16769902 15171703 22539306 25303530 7705655 16713569 1314167 16224062
MED10 MED6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15175163 12584197 15989967 24882805 10993082 14576168 33961781 24981860 22939629 26344197
NCOR1 NR3C1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SUMO1 TDG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MED21 MED31 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
NCOA2 NR3C1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NCOR1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA2 RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
HDAC3 NCOR2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
MED14 MED6 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
MED10 MED31 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED10 MED21 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED14 MED21 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED21 MED6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MED10 MED14 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MED10 MED6 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCNC CDK8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RB1 CCND1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CCND1 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
POU2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14645506 12391146 15282324 15885880
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
CTNNB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16628468 10318916 12095419 15111320 15735151 18679417 17360646 12782598 10201372 14557550 19778454 20300972 19662654 12589056 11943708 10915780 17693601 15592430 17109766
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CTNNB1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 11836555 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 17208333 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
CDK7 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7533895 19847258 12814430 17386261 16782892 17884153 19667075 15703371 12648680 11900249 12459251 16697054 19809470
CCND1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 9190208 7575488 10385618 9736735 8490963 26225123 19237565 7736585 19075565 18590585 27507850 26121043 20068082 9425340 18786381 17660363 10778858 9380698 27430527
CCND1 RBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16600870 10498883 10385618 9736735 12006580
CCND1 SUV39H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10385618 9736735 12006580 10498883
CTNNB1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18483247 12782598 17724465 10027409
FN1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1730778
CDK7 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23637584 15670742 15249124 33902658 22135230 12054865 19917671 30532072 11955452 19078967 16713569 21297158 16769902 9230306
CDK7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17591690 11709713 12064478 1088347 16083285 9372954 11483158 9620776 10348343 10884347 16552184 9315650 11007451 9571186 10747897 17898864 1454855 11585729
SRC EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25008017 24609268 19789182 29684168 24365856 17637040
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11864601
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
SRC HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7516469 17178840 24642125 12052863 7592945 16854432 16713569 21184736
MAPK3 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11259409 16564677 11231586
HNRNPK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18472002 16360036 23092970
IQGAP1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11319218 8226933 1330321 16135787 17563371 7992057 8248196
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
KPNA1 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11032817 26491019 10523667 26496610 9922449 9102465 17596301
PARP1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 10383391 12048211 10377179 15688020 18003614 27852823 17604322 11606411 20432439 16551633 12824162 15212693 17900311
MAPK3 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12351702 17440046 9199329 20047289
MAPK3 MED1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12356758 16314496
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 SUMO3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19779455 25218447 23750026 24782567
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PARP1 H1-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18250087 18851700 18927583
PRKDC HNRNPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27303920 25986610 19351595 25030905 19844162
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
PRKDC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 318.0 1.0 Omnipath 27120806 14555685 20028775 20176926 11287317 27542271 26740621 11731414 12393602 34197700 17993646 21940452 21946537 11278872 22975685 16908595 18316359 34073781 24735537 18039660 24652283 20856200 26170313 21300025 15388791 19144640 26297026 17545609 33941854 16280327 10625301 33845796 25918246 34385295 17537996 14645219 20804212 15084259 12169689 21795477 22071574 23913047 34021259 21695150 15684384 33958720 14530366 16670089 19487463 19223464 17303569 25481872 15475446 17116771 28967905 33753495 12438236 29562639 16753042 33836561 19073147 15169778 16891474 19477925 16338973 16397245 34562454 15821749 33767437 34087103 11409731 18381446 15737995 27481935 11313365 26700621 17210635 25447541 33931486 17827393 17126298 15262962 28542588 33574930 11821945 20471940 15461589 17077177 33579227 26921343 17386266 33744230 26848618 12944390 33566837 26902421 21042280 21763421 34380642 18321849 14593122 25775124 25739674 17229808 26351843 24102046 23757022 33532186 16043647 24632620 12781924 25738875 10864894 17974989 25719244 15806160 16497987 25851605 20501647 18439899 28209968 10973320 24819169 25745998 34383763 19592491 19244117 19204084 29088759 26871475 34257082 26755732 17237292 17709744 17640984 34405859 18480058 33995548 22310280 20211239 12052823 22580611 31937616 19920202 26745759 15905173 12499277 15028555 27162341 21106850 33562475 30065170 23462102 15678105 15642728 27065332 28558072 28977846 15319269 21339742 15855334 21045808 20145118 21297104 18632646 17379600 15471950 23474758 26887938 11375271 20013032 18701889 16540596 15314172 28515473 15964826 19638206 25892239 28692056 20530876 27505672 25100728 21242970 17297446 10542266 14670178 15548374 33741342 12429574 11002428 15831486 17116756 25435370 32833881 11402048 25361894 15207915 20729916 15625077 18677106 12869565 11250155 21356307 15967841 31936857 25943101 18394555 12644590 14500543 18691549 27197158 15623569 33477794 12062056 16754797 15383526 21909137 21949775 20085797 16807298 15899889 33868961 23940660 23434580 33927349 23899556 14990993 12000752 27880719 26065416 19060924 34520759 14679308 15334055 17283158 25257795 17548608 30586628 24437487 20124472 15289327 23325788 21208159 33664452 31679687 12791703 15047712 17166829 26146988 17329400 20660158 21532621 21806543 20179209 25661488 20957047 17562705 19915805 12606948 17277771 10377409 25893295 17270736 16407838 20597130 15047168 28658616 16357520 15537647 12818176 11425855 17210830 19800394 12506011 21310961 16963136 21996732 15695828 33835469 11701613 19010331 26686089 28915558 15467762 17586693 18456663 34381564 18765673 20233713 34208786 11029403 22084251 20622007 12077256 11313948 16917505 19448664 27391337 15792956 21172654 15608670 12438239 19875458 22014578 25071014 11809760 18728186 31391321 33891611 19805619 33407730 25868858 25320242 34348155 20832730
PRKDC POU2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17213819 9368058 14612514
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
SUMO1 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16763556 15959518 17060459 21284855 20504299 16189514 16524884 11889051 10961991
SUMO1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 12193561 12144530
TAF11 TAF7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 1346476 18234965 8554604 8898977 10745175 19714248 9988237 10029407 11096091 11172607 11920581 17952118 8679460 9112432 11350951 8502478 11483599 7949467
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
TP53 HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15289308 16230375 11382926 15964798
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
MED1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15848166 9444950 16713569 11118038
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
XRCC6 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2N PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655
UBE2N PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 18772547 12820959 18525240 19459846 19258535 19440234 17652783 15147722 10880451 15169778 19851286 10722742 18647995 18006823 18157158 16224103 20675655 16518696 18196958 15340381 10721693
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
NR3C1 CRH â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 8491092 24346134 15112058 10517666 22039522 18006628 24065704 23671328 9099914 22232675
SRC KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19050761 18662404 18194650 10749680 12509223 18377662 10455194 16966330 12214271
HDAC3 NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1X â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1X â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR2 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11509652 17694085 11804585 22230954 10944117 16924111 17126328 15837933
NCOR1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11509652 11013263 16195251 11931768 16469706 21258344 17694085 10860984 16917504 10944117 23752268 16713569 14527417 11466315 11804585 12628926 15601853
NCOR1 TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1X â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 TBL1X â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1XR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17620012 15060155 15601853 14980219
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 PDCD4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
PPARGC1A ESRRA â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16314495 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A ESRRA â—¼   PROTEIN_INTERACTION 23.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16314495 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
PPARGC1A ESRRA â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16314495 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
CREB1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20359506 17451429 17018277 21156859 11557984 22980225 15653680 19583954
AKT1 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17554339
PPARGC1A ESRRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12181319 18063693 15337744 12522104 32296183 18441008 15100410
TBL1X TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TBL1X TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TBL1X CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11389839 25241761 20181957 33054136 18193033
CDK8 MED12 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 MED13 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 CCNC â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 25416956 30695077 15328539 14681455 20098423 19047373 11867769 10882111 21806996 26496610 23602568 19914168 29568061 26502155 25344755 9710619 10024883 32707033 10353252 23746844 9150135 29997244 11416138 33961781 24981860 26186194 7568034
CDK8 MED12 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 MED13 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 CCNC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21806996 23746844 26186194 19914168 20098423 19047373 23602568 7568034 25416956 29997244 10882111 15328539 25344755 9150135 11416138 10353252 26502155
MED12 MED13 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
MED12 MED13 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
SRC PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21780115 15032589 11526404 23109003 22880054 10488096
SRC PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20643654 14585963 16314505 11481331 15212693 12738763 1148133 15302935
SRC PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 25003662 10978272 21292165 23796501 24676687 22771321 24395787 17635907 26378614 16286244 27013170 23222956 25726524 24997451 31992581 12921784 1325671 17303700 23251465 20558158 21554241 23926298 25931585 22299660 18208556 21791414 23436320 32130916 17394530
SRC RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10322133 23331499 15140878
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
SRC GLRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11882681
PDPK1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11687500 11747822 12670391 15802604 17680028 18802401 19109239 19122654
PDPK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 156.0 1.0 Omnipath 15505410 12538620 12176337 19951971 24352480 11752451 19401591 11369519 10698680 10601311 15718470 24950409 20481595 24169049 10570282 16798838 14993273 11500365 9368760 19844585 17680028 7637810 9169478 26256536 7722458 9094314 12750173 11438723 18802401 9252186 23331499 18456494 9104825 10592173 16189514 20361045 18988627 11278835 20163786 20333297 20041157 12808134 19602588 8630736 10207050 11241670 10438924 9868760 25912234 20153221 25582703 11445557 21775285 12149249 14666721 18596232 9512493 23397142 11809791 12167717 21798082 16033886 10679787 16787925 29562639 15550174 21071413 8978681 10833263 19203586 10226025 26937223 14500673 20161206 11136732 11825911 11042193 9642236 22569334 18662999 9736715 12242303 11313365 11598012 11134526
MEF2A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10973962 12138087 15931671 21689744
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16417524
AKT1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27997540 24291004
AKT1 GATA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 27053161 15837948
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
AKT1 PDCD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17053147 17081983 18296647 18187866 17287340 16357133 16964243 18669648
AKT1 ILF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20870937 18097023
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
NR0B2 ESRRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11705994 15604093
CREB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 2170405 22357921 8648265 15908479 1845987 8803927 2542772 15608673 1404598 1320003 12372774
CREB1 SST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1655749 8794339 1974651 7745688 1350057 8393039 1352885 7799950 1347642
CREB1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17526027 19155497 19750005
CREB1 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21406501 20688914 10854692 20022930 1655770 16803882 8093246 20797423 20137375 24046422 10085123 23058912 9593667 8386317 11092886 19583954
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
PPP2CA RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10921877 21159657 16885030 12370081 19890961 16916641 10702384 21376459
RARA RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10929206 16613989 7969156 8388240 2164682 1316240 8001825 1650576 16832676 16782888 10629053 2153268 9108446 1318502 10629091 11839811 11497266 9184230 14528273
RARB RXRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26871637 23331499 15604093 1331778 1310351 12112017 25416956 32296183 1310259
RARB RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20102612 12576329 23331499 7565739 1310351 23180781
CTNNB1 CDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10934025 11997022 12242722 12446687
RXRA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12771132 25241761
NCOA2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12612084 20543827 23331499 9192892 9430642 16713569 12503607
RXRB RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 26871637 25303530 23331499 20211142 15604093 1310351 21071413 10721822 31515488 16189514 32296183 16713569 18988627 29892012 1310259
NR0B2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 8650544 9773978 16713569 11368516
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
RXRA NCOA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11266503 29170386 12151000 9920895 9590696
NCOA2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12612084 11981034 15657427 23331499 21071413 9430642 10748178 11514567 18988627 11851396 17947383
NR3C1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18805405 7499421 17572486 10772626 11602528
NR3C1 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17095578 16100117 11557972 11333185 11069927 12560325 26652733
RXRA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19712670 18400206 16608838
THRA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11018031 23331499 15604093 1331778 1314167 19422879 11117530 16189514
NR0B2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 23331499 16189514 12198243 10594021
RB1 TRIP11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9256431 16713569
NR0B2 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15358835 20688914 18505831 18459945 19720831 17094771 22977252 12324453
NR0B2 RXRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 16189514 10845098 10594021
RXRB THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 10976919 1331778 10721822 16189514
OXT OXTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 10519430 8955347 12660315 10698266 16158071 7774575 7475979 1313946
TAC3 TACR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 7557266 8990205 10866201 9190866 1312036 11226387 10189055 2176308