Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HLA-DRA CD74 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CD74 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CD74 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CD74 LGMN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 8134367 18292509
HLA-DMB CD74 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2391366 8574855
HLA-DMA CD74 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2391366 8574855
HSP90AA1 LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17188549 16641196
CALR TAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
CREB1 TNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFYC NFYB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215853 12401788
NFYB CIITA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10913187 12697811
AP1B1 CLTA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8909539 11050117
PSME2 PSME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RFX5 HLA-DPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
IGF2R GGA3 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
CREB1 HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
HLA-A KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9405670 9295021
HLA-DRB3 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TAPBP CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
CD8A CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
CALR KLRC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HLA-C B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211709 10429675
HLA-C KIR2DS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24078689 11172020
HLA-C CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12899833 10809759
HLA-G KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21115737 21746965
M6PR GGA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11387475 5214102
HSP90AB1 LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17188549 16641196
KIR2DS4 B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19858347 15265913
CD4 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CREB1 CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9765424
HLA-DQB1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11535811
HLA-DPA1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12899833 16189514
GABARAPL1 ATG7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20562859
TAPBP PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
HLA-DRA LGMN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 8134367 18292509
HLA-DQA1 LGMN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 8134367 18292509
HLA-DPA1 LGMN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 8134367 18292509
HLA-DQA2 LGMN â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 8134367 18292509
HLA-B CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9331948 10809759
CREB1 HLA-DQB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1324879
CREB1 HLA-DOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12938212
HLA-DRA HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
SOD1 LAMP2 â—¼   COLOCALIZATION 2.0 0.8 intact 8141566 21252941
RFX5 HLA-DMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7495736 11258423
CIITA HLA-DMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7495736 9300700
HSPA5 PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFYA HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22530004
NFYC NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12857858 22969033
HLA-DQB1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11376336 5214072
HLA-DQA2 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
RFX5 HLA-DQA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
HLA-DQB1 HLA-DQA1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HLA-DQA2 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
RFX5 HLA-DQA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
RFX5 HLA-DPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
RFX5 HLA-DMB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7495736 11258423
RFX5 HLA-DQB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18723135 11258423
RFX5 HLA-DOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
RFX5 HLA-DRB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
RFX5 HLA-DOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
RFX5 HLA-DRB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
RFX5 HLA-DRB4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11258423
RFX5 HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18723135 11258423
HLA-F KIR2DS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27649529 24018270
RFXANK HLA-DOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12938212 11258423
RFXAP HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18723135 11258423
RFXAP HLA-DQB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18723135 11258423
CSTA CTSV â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HSPA2 HSPA8 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ATG7 GABARAPL1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
HSP90AB1 HSPA1A â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
IDS AP3M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
AP3M1 AP3B2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M1 AP3M2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TAP1 CALR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11823531 17055437
DEF1 LGMN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M2 AP3B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M2 AP3D1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP4S1 AP4B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
AP1G2 AP1S1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16713569 9733768
NPC1 LAMP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33144569
DEF1 NPC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3S1 AP3M2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP3M2 AP3S2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DEF1 MANBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DEF1 ARSB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARSG SUMF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GNS SUMF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ATP6V0B ATP6V1H â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HLA-DQA2 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
IGF2R GGA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5214130 11390366
LGMN ATG7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LGMN PDIA5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ARSA SUMF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ARSA GALNS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IDS PPT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IDS SUMF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 15962010 33961781 26186194
IDS GALNS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
AP1B1 AP1G2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
AP1G1 CLTC â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ATP6AP1 ATP6V0A2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HLA-F KIR3DL2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CIITA RFX5 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CD74 CTSL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
LGMN USP17L2 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ATP6V0D1 ATP6V1H â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
GGA2 GGA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14638859 31076515
HLA-DRB1 HLA-DRA â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220278 7477400
AP3B2 AP3D1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
AP3B2 AP3S1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 9118953 33961781
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ARSA GALNS â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
AP1M2 AP1S1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ATP6V0D1 TCIRG1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
B2M TAPBP â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
LGMN TRAF6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30906206 24610907
HLA-A KIR2DL3 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CD8A CD8B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
AP1M2 AP1S2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ATP6V0A2 ATP6V0C â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
GGA1 GGA2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ATP6V0D2 TCIRG1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
ATP6AP1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
CYTC LGMN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33961781 25630877
AP4M1 AP4B1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10436028 33961781
CD74 HLA-DRA â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
AP3S1 AP3M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781
AP3B1 AP3M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781 26344197
AP3S2 AP3M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 9182526
AP3M1 AP3D1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23144738 22863883 33961781 26344197
AP3B1 AP3S2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 9182526
AP3D1 AP3S2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15469849 9182526
AP4E1 AP4S1 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
AP4M1 AP4E1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10436028 33961781 26496610
AP4E1 AP4S1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10436028 33961781 26496610
NPC1 NPC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20674861 27238017
PSME1 PSME2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HSP90AA1 HSPA1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ATP6V0A2 ATP6V0D2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HLA-B KIR3DL1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSP90AB1 MAPT â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AP1G2 AP1S2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HLA-B KIR3DL2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TAP1 TAPBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ATP6V0A1 ATP6V0D1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AP3B2 AP3M1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
B2M KIR3DL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
B2M KIR2DL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
AP3B1 AP3M2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
AP4B1 AP4E1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CLTB CLTCL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HLA-A KIR3DL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
AP1B1 AP1G2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 33961781
CYTM LGMN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 25630877
HSPA4 MAPT â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ATP6V0C ATP6V0D1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HSPA8 MAPT â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AP3D1 AP3S2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
AP3B2 AP3S1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HLA-A PDIA3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
AP1B1 AMPH â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 9280305
PDIA3 TAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 9545232 17055437 11823531 30833792
GGA1 GGA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14638859 33961781 28514442
AP4B1 AP4E1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10436028 26496610 11409905 32073997 33961781
AP1M2 AP1G2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
AP1M2 AP1S2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
AP1M2 AP1S3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
HEXA HEXB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16698036 33961781
RFX5 RFXAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10938133 26496610 33961781 9118943 20732328
PDIA3 TAPBP â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CSTA CTSL â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CLTC GGA1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
HLA-DQA2 CD74 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
TAP2 TAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11133832 12213826 19297616 11381133 17055437 26789246 33961781 16828748 18802093 30833792 19201886
NFYB NFYA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 25416956 12857729 23332751 26496610 14681455 8051128 26344197 15243141 15831478 17098936 16959611
PSME2 PSME1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 8663520 16189514 9346951 22863883 33961781 19017543 22939629 9325261
KIR2DL2 IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C IFNG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
NFYA HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
PDIA3 CALR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 12052826 10436013 24981860 30021884 11823531 26344197
HLA-C KIR2DL3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 11513144 8574854 9751747
HLA-C KIR2DL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C KIR2DL2 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 11513144 21339333 9605119
HLA-C KIR2DL3 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 11513144 8574854 9751747
KIR3DL1 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
KIR2DL3 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
KIR3DL2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CD8A B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
KIR2DL2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
KIR2DS2 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
CD8B B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15136729 15534202 16551255
KIR2DL1 B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
B2M KIR2DL4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15580655 11861603 11955593
HLA-DRA CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA1 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DPA1 CANX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
RFXAP CIITA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12618906 15781111 11258423
RFX5 HLA-F â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14678199
HLA-DMA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
AP1B1 AP1M2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CLTA CLTCL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
AP1M2 AP1S1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 28514442 10535737 16189514 33961781 26186194
HLA-DPA1 HLA-DPB1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
AP3D1 AP3M2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
B2M CALR â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
B2M HLA-F â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HLA-B B2M â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8624811 5220994
AP3B1 AP3D1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 22863883 15469849 22939629 26344197
CALR TAPBP â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ATP6AP1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V0C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V0A1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0C ATP6V0D2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
B2M KLRD1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
AP1B1 AP1S3 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 23415225 33961781
GGA3 M6PR â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NPC1 NPC2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RFX5 RFXAP â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
HSP90AA1 HSPA1B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ATP6V0B ATP6V0C â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
B2M CD8A â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ATP6V0C ATP6V1H â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
AP1B1 AP1S2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 26496610 33961781 22939629 26344197
AP3B1 AP3S1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22863883 33961781 22939629 26344197
AP1M1 AP1S2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 26496610 33961781 22939629 26344197
HEXA HEXB â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
AP1G1 IGF2R â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
AP1M1 AP1S2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AP1M1 AP1S1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
HLA-E KLRC1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
B2M KLRC1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HLA-DMA HLA-DRA â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
AP1B1 AP1M1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ATG7 GABARAP â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CSTA CTSB â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
GGA1 SORT1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
AP1B1 AP1S2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP1B1 AP1S1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP3B1 AP3S1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
AP1G1 AP1B1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10535737 10747088 9733768 7593184 23415225 11409905 33961781 22939629 26344197
AP1B1 AP1M1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7593184 22939629 33961781 26344197
AP1B1 AP1S1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 33961781 24843023 26344197
AP3S1 AP3D1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 15469849 23144738 22863883 33961781 26344197
AP1M2 AP1G1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 10535737 16189514 33961781 26186194 26344197
AP1G1 AP1M1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10535737 10747088 7593184 22939629 26344197
AP1G2 AP1S2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16713569 9733768 26496610 33961781
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HLA-DRA HLA-DRB5 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HLA-DMB HLA-DRA â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HLA-A TAPBP â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NFYC NFYB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 21988832 26496610 35140242 33961781 20936779 9388234 12401788 26344197
AP1B1 AP1G1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
AP1M2 AP1B1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 10535737 33961781 26186194 26344197
NFYC NFYA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 12857729 14681455 35140242 33961781 20936779 26186194 15243141 26344197 23332751
AP1G1 AP1M2 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3D1 AP3S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KLRC1 KLRD1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
TAP1 TAP2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
AP1G1 AP1S1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RFX5 RFXANK â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
AP1G1 AP1M1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
AP1G1 AP1S2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
HLA-DMA HLA-DMB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
AP1G1 AP1S1 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 10535737 16189514 10747088 9733768 7593184 15758025 22939629 26344197
B2M HLA-E â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M HLA-C â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
B2M HLA-G â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
B2M HLA-B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
B2M HLA-A â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
AP1G1 AP1S2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 29892012 16189514 25416956 9733768 26496610 33961781 22939629 26344197
GGA2 IGF2R â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HLA-DRA HLA-DRB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GGA3 IGF2R â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HLA-DQA1 HLA-DQB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GGA1 IGF2R â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NFYA NFYB â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYA NFYC â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
AP1G1 CD74 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CD74 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CD74 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CD74 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
CD74 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
TNF CD74 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10925299 11112697 11438547 11875494 12646658 12811837 1431106 14607933 14625680 15099563 15699106 16713974 17916596 18633355 19411070 20038811 20184663 20435894 21133840 21411734 21826665 22595692 22955274 23170255 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 8910423
CTSS CD74 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10072073 10562280 16286017 22157818 22424724
LGMN CD74 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10795737 12705852 12776207 16181339 17204652
CD74 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-DRA CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1S1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1S2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
TAP2 TAP1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179
TAP2 TAP1 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 10973281 11717192 14508489 16181333 17204652 22076556 22790179
TNF SMPD1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
LITAF TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22138218 12177065 11708771 10200294 16804395 16872372 17283168 12655064 21980379
HLA-DQA2 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
ATG7 GABARAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20562859 17145710 11890701 16303767 11096062
GABARAP ATG7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20562859 17145710 11890701 16303767 11096062
KIR2DL4 IFNG â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
KIR2DS2 IFNG â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 9490415 9625766 9655483
HLA-G IFNG â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
CREB1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20979795 11907114 20006311 12928400 16713974 22413812 7759501 12626576 9834094 15879136 20685939 18641343 9503023
HLA-E KLRC3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
HLA-E KLRC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
HLA-E KLRD1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 15728498 15884055 20814939 22464172 23715743 24586048 24935923 2731048 8478617 9485206 9486650 9625766 9655483
HLA-E KLRC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
HLA-E KLRC3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
HLA-E KLRD1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 15728498 15884055 20814939 22464172 23715743 24586048 24935923 2731048 8478617 9485206 9486650 9625766 9655483
RFX5 HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8717517 10779326 12618906 12697811 14678199 9401005 9806546 11258423 17611194
RFXAP HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10779326 12618906 9806546 9118943 11258423
RFXANK HLA-E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16236793 12215433 10779326 12618906 9806546 16166641 11258423 7935401
B2M HLA-E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9605335 16189514 10064069 9660937
HLA-E KLRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26697006 9486650 9103421
HLA-E KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9486650 9886400 14734748 16189514 9815261
HLA-E KLRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9486650 24223577
KLRD1 KLRC3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
KLRD1 KLRC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
KLRD1 KLRC3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11015446 12731048 15728498 15884055 23715743 24586048 24935923 2731048 9486650 9625766 9655483
KLRD1 KLRC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11015446 12731048 20814939 23715743 24586048 2731048 9486650 9625766 9655483
HLA-B KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8046333 16189514
HLA-G KLRD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9405670 9295021 16189514
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CALR PDIA3 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CALR B2M â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
HLA-C KIR2DL1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C KIR2DL1 â—¼   PROTEIN_INTERACTION 6.0 1.0 ACSN 11513144 12515815 12917349 16606694 18835194 9751747
HLA-C KIR2DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 30761133 11955593 15580655 10190900 10850706 28484462 18322206
HLA-C KIR2DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 58.0 1.0 Omnipath 15580655 11163076 10429675 28484462 9686591 9768753 9378975 11323700 12454284 16141329 28546555 11955593 15607823 18624290 11009104 12794140 31519864 19858347 10820396
HLA-C KIR2DS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 28546555 31210416 28484462 18624290 9464792 7650491
HLA-C KIR2DL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 11955593 15580655 10497191 9768753 18322206 28484462 15607823 19858347 16189514 8692965 31210416
HLA-C KIR2DS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 28484462 9521070 15265913 31210416
KIR3DL1 HLA-B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
KIR3DL1 HLA-B â—¼   PROTEIN_INTERACTION 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HLA-F KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27649529 27455421 28484462
HLA-B KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11955593 15580655 22020283 25480565 8046332 15607823 17182537 25740999 16189514
HLA-A KIR3DL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28484462 17182537 31210416
HLA-G KIR2DL4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G KIR2DL4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 9625766 9751747
HLA-G KIR2DL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11955593 15580655 26973020 17056715 10190900 16487070
HLA-G CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1908512 10843658 10809759
HLA-G KLRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9560253 9295021
PDIA3 B2M â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CD4 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DRA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
HLA-DPA1 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-DQA1 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-DRA CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-DQA2 CTSS â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11684289 12078484 12748383 8687433
HLA-B KIR3DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23857132 23804219 28484462 17407096 23440420
HLA-B KIR2DL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 28514659 7931060 8760827 19858347
AP1G1 HLA-DRA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DRA CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CIITA HLA-DRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10886240 11889043 11429551 9300692 9600954
RFX5 HLA-DRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7744245 11258423 10586057
HLA-DQA1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1M1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1S1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTB HSPA8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9100026 6146630 17978091 26042225 20033059
HSPA8 CLTCL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9100026 6146630 17978091 26042225 20033059
HLA-DQA2 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1S2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-A CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9177355 10809759
HLA-A KIR3DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11955593 25033772 15580655 15719024 8760804 8617928
HEXA GM2A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2970528 1720305 527942 16698036 2971395
HLA-DQA1 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DPA1 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DMA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA1 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DOA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 HLA-DOB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DQA2 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
RFX5 CIITA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12618906 12697811 15247294 9177217 10913187
CIITA HLA-DMB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11889043 9300700 7495736 9600954 11332992
CIITA RFX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12697811 11003667 9177217 26871568
HLA-DOB HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DOA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DPA1 HLA-DMB â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 9606180 7481823 9075930 9311912 7667286 8046351 10631952
HLA-DPA1 AP1S3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-F KIR3DL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27455421 24018270 28484462
HEXB GM2A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2970528 1720305 527942 16698036 2971395