FADD
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15659383
25241761
|
TNF
|
SMPD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20080539
0908486107
|
TNFRSF1A
|
SMPD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12391233
20080539
|
TNFRSF1A
|
CASP8
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8095238
21157428
|
NSMAF
|
SMPD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12391233
20080539
|
SMPD1
|
CASP8
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8095238
21157428
|
YWHAZ
|
GDI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
MADD
|
NUP37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MADD
|
PTPRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
THRAP3
|
MADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
BBS7
|
RIPK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BBS7
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DOCK5
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SYT3
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MTMR8
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25659891
27880917
|
1433Z
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20936779
16959763
|
RIPK4
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26972000
33961781
|
LOX5
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ANM6
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
SNX21
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SYT12
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SYT6
|
SYT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NXPH2
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
SYT6
|
MADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CASP2
|
PIDD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
SYT3
|
SYT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9727492
15659383
9727491
12097160
11832478
12196516
11085743
|
CASP8
|
BID
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
9727492
|
TNF
|
NSMAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8663014
8808629
11435466
|
CASP8
|
FADD
|
â—¼ COLOCALIZATION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219431
17159907
|
FADD
|
CASP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21785459
23142077
21988832
23972990
17290218
24098568
14681455
20103630
33469115
18485876
22274400
22864571
25043603
27560715
25939870
29795330
19524512
17159907
30561431
27552911
19176810
15659383
9343261
22179575
22173242
25911380
27321185
8681376
15280356
21737330
26437781
31046799
21458669
12702723
11717445
21737329
19060883
21525013
23429285
20448643
12107169
17047155
9228018
12887920
29497034
12911633
14612908
23955153
33961781
20829884
26972597
21620750
|
CASP2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
16189514
11085742
11085743
16495337
|
CASP8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
12196516
18458084
9727491
11085742
11085743
12097160
9873064
|
PIDD1
|
CASP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15073321
16189514
19203584
16652156
|
CASP2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15262979
16193064
|
TNF
|
MADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
14716293
11577081
19289468
17314102
16682944
|
TNF
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNF
|
FADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
TNFRSF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNF
|
FADD
|
â—¼ SHARES_COMPLEX
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
NSMAF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNF
|
SMPD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNF
|
TNFRSF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
98.0
|
1.0
|
Omnipath
|
17145710
19084540
8288897
11448951
23746843
22801493
14732063
2848815
9568681
2158863
8182064
9488135
23070005
20080539
11239407
26670046
14743216
21724995
21133840
24070898
25911380
7852363
2170974
17151142
26186194
27560715
25241761
23032187
24726327
20103630
8805640
11502070
19442713
3034874
23955153
18067990
22099304
15485837
22675546
12753742
1310388
12887920
19287455
10634209
2170559
1331108
24980434
22028622
|
TNFRSF1A
|
MADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
14716293
11577081
19289468
17314102
16682944
|
TNFRSF1A
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
TNFRSF1A
|
SMPD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNFRSF1A
|
NSMAF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNFRSF1A
|
NSMAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12391233
10187805
17599063
8808629
|
TNFRSF1A
|
FADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21760970
15357952
15033800
21741934
9129204
|
TNFRSF1A
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15357952
12887920
21741934
8875942
15725726
|
TNFRSF1A
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12655147
21614932
12738796
11274345
18855897
|
RAB3A
|
MADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
1845915
27246931
7911226
20937701
21776405
16571673
25341920
11516400
12244319
9136770
9020086
8144603
|
CASP8
|
FADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
FADD
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11003656
15325588
17462996
20531300
23725295
24070470
26587781
26972597
28574505
9488730
|
FADD
|
CASP8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
11003656
15325588
17462996
20531300
23725295
24070470
26587781
26972597
28574505
9488730
|
FADD
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
82.0
|
1.0
|
Omnipath
|
22864571
17145710
11717445
19524512
34591612
15280356
17047155
27552911
12911633
25043603
21458669
11788820
19176810
21525013
21988832
22179575
25939870
12702723
21737330
21741934
26437781
25911380
9228018
21785459
20829884
23972990
21620750
12220669
9774341
17159907
10521396
27321185
17290218
27560715
20103630
24098568
20203691
14612908
8681377
18485876
12107169
15659383
22421964
20448643
9343261
20125124
8681376
12887920
19060883
21737329
23142077
22173242
26972597
22274400
19935698
16410793
|
RAB27A
|
MADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
21554507
20937701
16571673
23678941
16880209
18559336
|
NSMAF
|
SMPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11279185
11435466
12404124
12531547
1330325
16716889
24021978
28765050
8663014
|
NSMAF
|
SMPD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11279185
11435466
12404124
12531547
1330325
16716889
24021978
28765050
8663014
|
GDI2
|
MADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
21554507
20937701
16571673
23678941
16880209
18559336
|
GDI1
|
MADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
21554507
20937701
16571673
23678941
16880209
18559336
|
CHM
|
MADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
21554507
20937701
16571673
23678941
16880209
18559336
|
CHML
|
MADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
21554507
20937701
16571673
23678941
16880209
18559336
|