Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RPA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
RPA3 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR MCM6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21070963 20068231
CCND1 ORC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CCND1 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CTCF CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18625744
CDT1 CDC5L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC5L MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC5L CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC5L MCM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC5L MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
RPA2 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDK2 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
CDK2 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDK2 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDK2 MCM6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
CDK2 CDC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
CDK2 MCM7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
CDK2 MCM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
MCM10 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC45 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC7 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CCDC85B CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM7 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16289477 5218065
CDC6 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDKN1A CCND3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM10 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC7 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM5 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ORC4 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC45 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC6 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDKN2A CDK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDKN2A MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
DAPK1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11146619
E2F4 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12766778 18319725
DDB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 CDT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F1 CDC45 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10692433
E2F1 MCM10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15195143
E2F1 MCM6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10327050
E2F1 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F1 MCM5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 17210690
E2F1 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F1 MCM10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15195143 18319725
E2F1 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766737 18319725
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
MCM7 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC IKBKG â—¼   COLOCALIZATION 2.0 0.8 intact 20970423 8045055
RPA3 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
RPA2 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM3 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ORC4 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDK6 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CCDC85B MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM7 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
TNIP1 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CEP70 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RPA1 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC6 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
DAPK1 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
RPA4 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM6 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ZBTB8A MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DPPA2 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CEP72 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM2 MCM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM10 NINL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM10 CALCOCO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM10 ZBTB43 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM10 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM10 ORC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM10 HOOK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM10 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
MCM10 TRIM37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
E2F2 MCM10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15195143
E2F4 MCM10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15195143
E2F4 MCM10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15195143 18319725
ORC4 MCM7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
ORC3 MCM7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM7 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
MCM7 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM7 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
E2F2 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F2 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 14990995
E2F4 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 14990995
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
E2F2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
RPA1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17666013 9214288
CDC45 RPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM3 RPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC7 RPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
RPA1 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC7 RPA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
RPA2 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC7 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM5 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM4 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM3 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC45 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
RPA3 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM2 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC45 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM4 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM3 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM5 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC7 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
RPA4 MCM6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
RPA4 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
RPA4 CDC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDK6 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDK6 CCND3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
ZBTB8A CEP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CEP70 CCDC85B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ORC4 ORC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ORC2 MCM6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
ORC2 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ORC2 CDT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
E2F4 MCM3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10766737 18319725
E2F4 MCM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
E2F4 MCM6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
E2F4 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
CDC7 CDC45 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660782 10518787
CDC45 ORC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDC45 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660782 10518787
CDC7 CDC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
MCM5 CDC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
CDC6 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
E2F2 CDC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12411495
E2F2 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766737 18319725
ORC4 CDT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
CDT1 ORC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
E2F2 CDT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14990995
E2F2 CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 14990995
MCM6 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MCM5 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ORC4 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
MCM2 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
MCM2 ORC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
ORC4 MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM6 MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
MCM3 ORC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
MCM3 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
ORC4 MCM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
MCM4 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
ORC4 MCM6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
MCM6 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
MCM6 ORC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
E2F2 MCM6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10327050
MCM5 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
DAPK1 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
E2F2 CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12611887 18319725
ORC4 MCM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25231993 11125146
CTCF NCBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
PCM1 KRT15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDK2 MCM3 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 21965652
CDC45 POLA1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CDC5L MCM5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15232106 20467437 16189514
MCM10 CDK6 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15232106 16189514 16713569
CDK6 MCM2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15232106 16189514 16713569
DBF4 MCM4 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
MCM4 RPA2 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
MYC CDC5L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CDK2 E2F4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25852190
IKZF5 MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TPH1 MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CAV3 MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NINL MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16189514 26638075
MYC MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CCG5 MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RELL2 MCM10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MCM3 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC NXF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
MYC MCM6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CCND3 CDK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16782892 33854235 26496610 9716181 33961781 26186194 23455922
TX264 MCM10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TM171 MCM10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MCM10 MCMBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CDC7 MCM7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12614612 10846177 22540012
MCM3 CDC45 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12614612 27621311 23364835
CDC7 MCM4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12614612 10846177 22540012
CDT1 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22451935 15448697
CUL4A CDT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17079684 14578910 15448697
CDC45 CLSPN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 23910567
CDK2 MCM3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CDC7 MCM3 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MCM10 A4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 21832049 33961781
CDT1 MCM7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25990725 18162579
CDC45 MCM7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16912045 12614612 10518787 23364835
VPRBP CUL4A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17079684 17630831 20870715 18606781 30590706 31973889 17609381 25532805 21145461 19295130 30166453 33355139 16949367
MCMBP MCM3 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24299456
MCMBP MCM4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24299456
MCM4 ORC4 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
MCMBP MCM6 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24299456
MCMBP MCM5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24299456
CCND1 CDKN2A â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CEP72 PCM1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MCM10 POLA1 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 19608746
RPA1 RPA4 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MCM2 RPA1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
MCM3 CDK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15232106 16189514 21965652
CDK2 CDC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9566895 9889196 10339564
PCM1 MCM10 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26638075
CDC7 MCM3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15232106 9250678
MCM6 ORC2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCND3 MCM10 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ORC2 CDK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15232106 16189514 11931757
KBTB5 MCM10 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
MCM10 MCM3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15232106 11095689 16189514
MCM10 CCND3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15232106 16189514
MCM10 MCM2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15232106 11095689 16189514
MYC CDK6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22094256 28628118 28205554
MYC MCM4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
MCM5 MCM4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 26344197 11248027 33961781
CDK6 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 16508017
MCM2 MCMBP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDC7 MCM10 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDC5L ORC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15232106 20467437 16189514
MCM10 MCM4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 11095689 33961781 26186194
CDC7 MCM7 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MCM5 ORC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12614612 26344197
MCM3 ORC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12614612 11046155 12364596
CDC45 MCM6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12614612 19805216 23364835
MCM2 MCMBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25036637 25963833 22540012 33961781 24299456
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DBF4 ORC2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CDK2 ORC2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
E2F1 CDK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8458319 7969176 9199321 1530885 11245432
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
CDC45 MCM2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22374673 26167883 23364835 19805216 30392930
CDT1 CDC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15232106 25990725 14672932 18162579
CDC6 MCM3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15232106 10464337 11046155
MCM6 ORC4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK2 CDT1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MCM7 ORC4 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
MCM5 ORC3 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
ATR IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21872579 18583959
ATR DBF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22123827
CCND1 CDK2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CCND1 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
E2F4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10594784 7929342 9584162
CDT1 CDK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15004027 26496610 31160578 15855168 14993212 23455922
CDKN1A E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CUL4A DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22952844 17079684 22118460 15448697 26613412 22910413 25349427 21145461 22474075 27462452 16473935 15811626 18606781 26231201 18593899 16678110 16964240 33536335 19295130 25982117 33759138 16260596 27113764 21113133 30898011 28886238 26976604 27203177 17392787 25795299 22939629 26344197 14739464 27294876 10585395 27573245 31911655 17041588 20870715 27203182 31973889 32235678 16861906 19966799 22342275 34251884 17626091 19287380 30945288 16949367 32140073
DDB1 VPRBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21957298 25499532 26613412 30166453 17314515 18606781 28416635 24558487 19295130 30590706 24412650 17609381 27571178 25532805 16949367 28202763 27354282 20870715 25557551 19287380 33355139 26344197
E2F4 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14576826 10208422
E2F1 POLA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18347061 7929342
E2F1 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12611887 16300731
E2F4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18328430 18319725 14990995
E2F1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15014447 11491305
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
E2F1 RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11313881
MCM7 MCM10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15232106 11095689 16189514 28514442 26186194
MCM10 MCM6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15232106 11095689 16189514 25416956 28514442 26496610 26186194
MCM10 ORC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15232106 11095689 16189514
CTCF MCM10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MCM10 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15494305 19608746
MCMBP MCM7 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24299456
MYC MCM7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 17314511 29467282 30415952
MCM7 MCMBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 25416956 24299456 25036637 22540012 26871637 17296731 26344197
MYC MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
E2F4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11564866 12150994 18319725
MYC CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10899308 17093053
E2F4 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15574595 18319725 16135806
RBX1 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16189514 15448697 10230407 12481031 17452440 22474075 11861641 18593899 30349055 19295130 22405651 33759138 30352932 27113764 26976604 27203177 26990986 19250909 27203182 31973889 32235678 29958295 22863883 33961781 33504946 19287380 30945288 32140073
CDK6 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CCND3 E2F4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
MCMBP MCM3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24299456 25036637 22540012 30108253 27621311 33961781 24190967 17296731 26344197
MCMBP MCM4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17296731 24299456 22540012 25036637
MCMBP MCM6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24299456 25036637 22540012 26496610 24190967 17296731 26344197
MCMBP MCM5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24299456 25036637 22540012 33961781 17296731 26344197
E2F2 MCM5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10327050 24038359
ORC4 ORC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15232106 15910003 11395502 10402192 11323433 17716973
PCM1 CEP72 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 23443559 26638075 34079125 26297806 19447967
CDK6 CDKN1A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DBF4 MCM7 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DBF4 MCM2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CUL4A VPRBP â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ATR RPA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MCM4 ORC3 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ORC2 MCM7 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 12614612 20808282 16189514
ORC3 MCM7 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 12614612 15232106
MCM10 MCM4 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
MCM10 MCM3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
MCM10 ORC2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CDC6 CDT1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
MCM4 ORC2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 12614612 12364596
CDC6 MCM2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 15232106 23405012
ORC4 MCM3 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 12614612 16189514 15232106
CCND3 CDKN1A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CDC6 ORC4 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CDC6 MCM4 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CDC7 MCM7 â—¼   PHOSPHORYLATION ✅ + 0.94 0.94 Signor 21070963
CDC7 MCM5 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CDK2 CDC6 â—¼   PHOSPHORYLATION ✅ - 0.94 0.94 Signor 10339564
MCM3 ORC4 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CDC7 MCM2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 23066029 10846177 16446360 16826239 12614612 11568184 22540012 17927916 18286467 10523313 30392930 16899510
MCM6 MCMBP â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
MCM4 ORC2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
MCM10 MCM7 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CDC45 MCM4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
MCM4 MCMBP â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
CCND3 CDK6 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CCND1 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9840943 28514442 8647086 33854235 8479754 26496610 33854239 33961781 23455922 21654808 9178893
RPA1 RPA2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24207024 22939629 26399832 26496610 24981860 16514417 19214185 26344197
ORC2 MCM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12614612 16189514 15232106
MCM4 MCM3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16902406 12614612 27621311 33961781 30108253 22939629 26344197
CDC7 MCM4 â—¼   PHOSPHORYLATION ✅ + 0.96 0.96 Signor 21070963
CDC6 MCM6 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MCM7 ORC3 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CDC7 MCM2 â—¼   PHOSPHORYLATION ✅ + 0.96 0.96 Signor 19647517
CDC7 MCM6 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CDC6 CDK2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDC45 MCM10 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDK6 CCND1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15232106 16713569 10022865 24855949 17517622 33854235 11739795 14681455 24953629 11360184 33961781 10580009 17420273 21654808 11160398 9178893 19075005
MCM4 MCM7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12364596 12694531 20808282 8631321 8798650 12207017 9099751 12614612 7601140 10748114 23764002 24299456 15232106 22939629 17296731 10567526 22540012 22863883 27173435 26344197
MCM7 CDC6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23405012 12614612 25990725 10464337 23397142
CDK6 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8153045 21516116
CDK6 CCND3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 33854235 14681455 21516116 32296183 17517622 9716181 11360184 30217970 23602568 15232106 26264872 27107012 32707033 16782892 16713569 8114739 29997244 32814053 33961781 26186194
ORC3 ORC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15910003 20850016 12614612 26496610 16549788 31160578 11395502 17525332 10402192 11323433 12004060 22939629 17716973 26344197
CDT1 MCM6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 20202939 12192004 18184650 21099365 22140117 18162579 26496610
MCM3 MCM6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15232106 28514442 16189514 22939629 12614612 26496610 22863883 27621311 33961781 30108253 17296731 26344197
MCM7 ORC2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDC6 ORC3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MCM2 ORC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDC7 DBF4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
MCM7 MCMBP â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
MCM5 MCM6 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 22939629 25963833 11248027 17296731 26344197
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK6 CDKN2A â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MCM10 MCM2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
MCM3 ORC2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCND1 CDKN1A â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MCM5 MCMBP â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDC45 MCM7 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CDC7 MCM4 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CDC6 MCM3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MCM5 ORC2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CDC45 MCM3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CDC45 MCM6 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CDC45 MCM2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
MCM5 MCM7 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15232106 16189514 12614612 20808282 11248027 23993743 23764002 33961781 22939629 9099751 26344197
MCM3 MCM7 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 17296731 16189514 22939629 26264872 12614612 20808282 8631321 7601140 23993743 27621311 23764002 33961781 30108253 11779870 10464337 9099751 26344197
MCM7 MCM2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 12694531 20808282 8798650 12207017 14681455 9099751 12614612 10748114 23764002 15232106 25963833 30100344 22939629 17296731 10567526 22540012 22863883 33961781 27173435 26186194 16899510 26344197
MCM7 MCM6 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 22939629 12694531 12614612 20808282 16438930 26496610 12207017 23764002 27173435 17296731 9099751 26344197
ORC4 ORC2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15232106 9353276 16189514 15910003 20850016 31467278 12614612 16549788 31160578 11395502 11323433 12004060 17716973
CDC6 ORC2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12614612 11046155 15232106
MCM5 MCM2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15232106 16189514 22939629 25963833 12614612 24207054 22540012 11248027 14681455 23993743 16899510 17296731 26344197
MCM3 MCM2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15232106 28514442 16189514 26167883 31467278 25963833 12614612 22540012 30108253 14681455 23993743 27621311 33961781 16899510 17296731 26344197
MCM5 MCM3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15232106 28514442 16189514 12364596 26264872 25963833 12614612 22540012 11248027 23993743 22863883 27621311 33961781 25843623 30108253 22939629 26344197
MCM10 MCM6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CDC6 MCM7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDC6 ORC2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MCM2 ORC2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDC6 MCM2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MCM3 MCMBP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDC7 MCM2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MCM2 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM6 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ORC2 ORC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM5 MCM6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ORC3 ORC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM3 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM5 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM4 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM2 MCM3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM2 MCM4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM3 MCM4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ORC2 ORC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPA2 ATR â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM5 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDT1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM4 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM7 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC45 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RPA2 ATR â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM4 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM5 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM7 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDT1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC45 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATR â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDT1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC45 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM7 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM5 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR MCM4 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18309293 24500207 19473886 12766152 18077418
ATR E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22184068 11459832 15494392 15140942 26843428 27028861 20413589 27025900 24741006 23202967 25101673 27903963 27827925 15838517 22174788
ATR RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 28666352 23684611 19440044 20860841 18289945 24819595 25520194 19843584 10608806 26057167 17035231 24906880 27908669 22977173 25249630 25070753 26271993 23319600 26212458 29875999 24965470 26474068
ATR MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 18309293 22179839 18691976 15448142 16899510 30062004 19690332 18077418 16446360 24685613 15210935 17525332
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
CDKN1A CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 26203195 23443559 17145710 25416956 7478582 9837900 21988832 21516116 7777546 15232106 16082198 27107012 15695403 8657154 8242751 23007395 9106657 12383116 17556661 8756624 8662825 31515488
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
MYC CDK2 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
MYC CDK2 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 19887899 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 24954210 25002027 28536364 7575488 9618481
CDK2 MCM4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM6 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 E2F1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
CDK2 MCM7 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 RPA2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 CDC45 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 CDC6 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM5 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 CDT1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 CDKN2A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
E2F4 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 22447046
CDK2 MCM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 17081983 17303408 19793801 15279786 7575488 11454864 16517729 20068231 17116885 17582221 16519687 10748114 18669648 18590585 12714602 17660363 19651622 17296725 17924679 17102137 16964243
CDK2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8386367 27653698 17081983 19966300 18669648 29896817 17570479 20713526 17558397 15103331 22348395 20445224
CDK2 ORC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7575488 18590585 17296725 17303408 11931757 17102137 17116885 19793801 17582221 15232106 16189514 17660363 22334659 15279786 24732362
CDK2 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7575488 18590585 17296725 17303408 21965652 30062004 17102137 17116885 19793801 17582221 15232106 16189514 17660363 15279786
CDK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17570479 25101673 16213134 17660363 12006580 11420722 15279786
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 17303408 23129444 19793801 15279786 7575488 20068231 17116885 17582221 17570479 9889196 27207654 16153703 18590585 29760377 18691976 10339564 14749377 19343071 17660363 16707497 17296725 24216307 23479742 17102137 15212693
CDK2 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7575488 18590585 17296725 17303408 16899510 17102137 17116885 19793801 17582221 16446360 17570479 26549452 17660363 15279786
CDKN1A CDK6 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517297 17092340 9106657 18710949 24515438 20843055
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
E2F1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9748148 9191053 16923815 17008321 10030670 10702805 15048076 17167174
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
RBX1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11278750 15340381 12820959 15688063 18381890 19440234
CDK6 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 25121590 20102411 15964852 22375140 15232106 16713569 16508017 19440234
CDKN1A CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 21988832 23443559 26186194 25241761 27107012 8756624 25416956 16328436 31515488 16189514 15232106 32296183 23880157 26496610 9716181
CDKN1A E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
E2F1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11314038 12766778 20664976 10914734 16211008 10594030 11062467 11705881 11526499 15716352 19641316 21765927 22621932 19115249 11870517 12695664 20580656 15175242 17912037
CTCF CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22025288 12524457 19340300
E2F2 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18319725 11883935
E2F1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11314038 16135794 11883935 12446760 18319725 15175242 11034215
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
CDKN2A CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17881001 26186194 23602568 9751050 11739795 11556834 9380698 15232106 16713569 17955473 10491434 16915296 17909018
RPA3 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
E2F1 MCM7 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15279786 17218262 17303408 17660363 18328430 18590585 7575488
E2F1 CDC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11799067 18541154 12411495 19633359
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F1 DBF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18503552 12015319
CDK6 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCND3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
E2F1 CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18319725 14990995 19541929
E2F1 DBF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18503552 18319725 12015319
TNIP1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 16684768 18212736 20010814
RPA1 MCM7 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
CLSPN MCM7 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 MCM7 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM7 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
MCM7 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDT1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
RPA2 MCM7 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM7 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM7 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
MCM7 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDT1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
RPA1 MCM7 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM7 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
CDC7 MCM7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
RPA2 MCM7 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
CLSPN MCM7 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM7 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
E2F4 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 14990995
DBF4 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7575488 18590585 17296725 17303408 12614612 10846177 17018296 17102137 17116885 17582221 19793801 16189514 17660363 15279786
CDC7 MCM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7575488 18590585 17296725 17303408 12614612 10846177 17018296 17102137 17116885 17582221 19793801 21070963 17660363 15279786
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
E2F4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24573694 17132729 17699159 11689553 12757710
MYC CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682794 22395148 12835716
RPA3 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC45 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CDC6 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM6 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM5 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDT1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 MCM4 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM6 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDT1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM5 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM4 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC45 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC6 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
DBF4 RPA1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
CDC7 RPA1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM5 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM4 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC6 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM2 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC45 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM6 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 MCM6 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC6 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM5 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 CDT1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC45 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM4 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM6 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC6 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM4 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM5 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC45 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDT1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
DBF4 RPA2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 RPA2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
RPA2 MCM2 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM4 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC45 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC6 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM6 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM5 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA3 CDC45 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 MCM5 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM4 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDT1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDC6 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM6 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM5 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDT1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDC6 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM6 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM4 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDC45 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
DBF4 RPA3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 RPA3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
RPA3 MCM5 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDC45 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM6 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDC6 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM2 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM4 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
E2F4 RPA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 11799066
CCND3 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17517622 8114739 26186194 27107012 23602568 10477583 16782892 21516116 25416956 29997244 31515488 32814053 15232106 32296183 11360184 16713569 9716181
ORC2 CDC6 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 15707891 25762138 28112645 22405012 23851460 29899147 15684404 34131285 32848132
E2F4 CDT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 14990995
E2F4 CDC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 11799067 17671431
E2F4 E2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 21247883 9149906 15718499
E2F4 MCM5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 11799067
E2F4 CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18319725 16135806 17251008
E2F4 CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18319725 16144839 14990995
CLSPN MCM5 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM4 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDT1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC45 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDT1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM5 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC45 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM4 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM5 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM4 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDT1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC45 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
MCM3 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC45 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC45 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC45 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC45 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC7 CDC45 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 CDC45 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
MCM6 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
ORC4 CDC6 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 15707891 25762138 28112645 22405012 23851460 29899147 15684404 34131285 32848132
MCM4 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 CDC6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC6 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 CDC6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC6 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC7 CDC6 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 CDC6 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
MCM5 CDT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14672932 16824194 23603117 25231993 23851460 19896182
MCM3 CDT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14672932 16824194 23603117 25231993 23851460 19896182
MCM4 CDT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14672932 16824194 23603117 25231993 23851460 19896182
MCM2 CDT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14672932 16824194 23603117 25231993 23851460 19896182
CDT1 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDT1 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC7 CDT1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 CDT1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
MCM3 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16902406 12694531 22939629 12614612 25963833 10567526 22540012 8798650 14681455 22863883 33961781 27173435 16899510 17296731 26344197
MCM6 MCM2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16189514 25416956 12694531 20211142 14681455 12207017 12614612 26496610 25963833 30100344 22939629 17296731 26167883 10567526 22540012 22863883 33961781 27173435 16899510 26344197
MCM3 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC7 MCM2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7575488 18590585 17296725 18286467 17303408 12614612 10846177 17018296 17102137 17116885 17582221 19793801 16189514 26167883 17660363 15279786
CDC7 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 17303408 12614612 19647517 17018296 19793801 11568184 26167883 18286467 17062569 15279786 7575488 30062004 17116885 17582221 10523313 16446360 18669648 23066029 18590585 16826239 16899510 10846177 24902048 17660363 17927916 17296725 16864800 17102137 20177074
MCM4 MCM3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
DBF4 MCM3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 MCM3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 7575488 18590585 17296725 17303408 17018296 17102137 17116885 17582221 19793801 15232106 9250678 17660363 15279786
DBF4 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7575488 18590585 17296725 17303408 12614612 17018296 17102137 17116885 17582221 19793801 16189514 17660363 15279786
DAPK1 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18283219
MCM4 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM6 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16902406 12694531 12364596 12614612 22939629 26496610 8798650 12207017 22863883 27173435 17296731 26344197
MCM4 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
DBF4 MCM4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 MCM4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7575488 18590585 17296725 17303408 17018296 17102137 17116885 17582221 19793801 17660363 15279786
CDC7 MCM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7575488 18590585 17296725 17303408 12614612 10846177 17018296 17102137 17116885 17582221 19793801 21070963 17660363 15279786
MCM6 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
DBF4 MCM6 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 MCM6 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7575488 18590585 17296725 17303408 17018296 17102137 17116885 17582221 19793801 17660363 15279786
CDC7 MCM6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7575488 18590585 17296725 17303408 17018296 17102137 17116885 17582221 19793801 17660363 15279786
DBF4 CDC7 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 CDC7 â—¼   PROTEIN_INTERACTION 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM5 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 MCM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7575488 18590585 17296725 17303408 17018296 17102137 17116885 17582221 19793801 17660363 15279786
CDC7 MCM5 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 MCM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7575488 18590585 17296725 17303408 12614612 17018296 17102137 17116885 17582221 19793801 17660363 15279786