Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15837784 11466608
MCPH1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16217032
XPC ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16849332
RAD23B BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16712842 5218673
BRCA2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19369211 0811159106
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
FANCD2 BRCA1 â—¼   COLOCALIZATION 2.0 0.8 intact 11239454 5213674
SMAD3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768112 15735739
MCPH1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15220350
BRCA1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15574597
BRCA2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MCPH1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19549900
BRCA2 POLH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24485656
CDK1 RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12930972
RPA2 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
NBN CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25558984 22231403
CHAF1A CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CDK2 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDK2 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDK2 MCM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
PCNA CHAF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CHAF1A CCNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CHAF1A XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
PARP1 CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
XPC CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
RAD23B CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
XPA CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
CHD1L DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
CHEK1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20639859 8010047
RPA2 CHEK1 â—¼   COLOCALIZATION 2.0 0.8 intact 20639859 8010047
CHEK1 FANCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19861535
PARP1 DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
XRCC5 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
GTF2H3 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8652557 10734072
GTF2H4 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9118947 10734072
ERCC5 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8652557
ERCC6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16319174
TOP3A FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8140640 21240188
FANCA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FANCB FANCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16720839 17396147
VIM FANCG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PCNA FANCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20937699
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SPTA1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12700044 2809592
POLD1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DROSHA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GTF2H1 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259578 26278177
SIRT1 HSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23349863 19229036
HUS1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TAF1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17085686 9285713
TOP1 LIG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 13679147
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
CDKL5 MLH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
POLL MUTYH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0907280106 19820168
PARP1 RAD23B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 SPTA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PARP1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16647857
POLA1 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 PCNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660172 2165567
POLA1 PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
POLA1 POLA2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
RPA1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17666013 9214288
PRIM1 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
PRIM2 POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
PCNA POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660172 2165567
PRIM1 POLA2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
PRIM2 POLA2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
POLD1 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 10852724
POLE2 POLE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 32296183
SP1 POLI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22509890 21787586
LMNA POLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17099721
POLL XRCC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18971944 7294748
XPA PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0915085107 20304803
VIM RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAD9A CLSPN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20424596 7897378
RPA1 PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5222806 17673209
TIPIN RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17644383
MCM5 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
MCM5 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
DLD TAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VIM TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VRK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22621922
PCNA XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
SMAD3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XRCC6 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PCNA PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660172 2165567
PCNA PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660172 2165567
ACTB POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10773068 435297
SMAD3 DGCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21102523
SMAD3 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15292219
PRIM2 PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
PRIM2 PRIM1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
PRIM2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
LRRK2 AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ARRB2 KIF3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23074268 16908539
DROSHA SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SP1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11133225 7499419
SP1 SRF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10602487 10330138
SP1 PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8476854
LMNA YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SRF GATA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11003651 11158291
IRF2 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9625761 9490737
BLM RPA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
GATA4 NKX2-5 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
AURKB CENPA â—¼   PHOSPHORYLATION 0.8 0.8 Signor 11756469
CCNA2 PCNA â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RAD1 RAD17 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
GINS1 POLE â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
BRCA1 SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19768112 15735739
CDC5L MCM5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15232106 20467437 16189514
CDK1 CCNA1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 7799941 1628647 14681455 8565853 16009130
FANCL FANCF â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 27986371 16474167 24910428 16720839
MSH4 RAD51 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11950880 15489243
RAD51 MCPH1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19549900 20107607 32735676
CHEK1 RAD51 â—¼   PHOSPHORYLATION ✅ + 0.81 0.81 Signor 15665856
GTF2H2 POLR2A â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
RAD18 TP53BP1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
BLM PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24239288
BRCA1 ETAA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27723720 29656893
CDC5L LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 25948554
CDC5L RAD18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 31076518
VCAM1 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CDK2 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
LRRK2 CHD1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 26496610
CHD1L XPC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CHD1L XRCC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19661379 19666485
CHD1L HLTF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CHD1L PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19661379 19666485
ERCC6 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16107709 32355176
SPTA1 FANCA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16889989 12571280
FANCA RMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22343915 12973351
VCAM1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
GTF2H3 POLR2A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
KAT2B KAT2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10373431 24981860
SP1 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16050810 15647279
SMAD3 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 15994459
MDC1 DGCR8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34188037 29656893
BMI1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20668194 34316702
RAD18 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31076518
VCAM1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VRK1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28927264
POLH ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RFC4 RAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARRB2 RAD18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
XRCC5 RFC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12393188 26344197
RFC1 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30585729 26344197
VCAM1 TOP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 TOP2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
XRCC6 XPC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 XRCC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CENPA XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20080577
VCAM1 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 CDK5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 26268594
LRRK2 SFXN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
BMI1 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26468281 34316702
AIFM1 SFXN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27218139
VCAM1 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MCM5 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24623722 25963833
VCAM1 MCM5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ATM CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 20068082
ACTB H3F3A â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
BLM RPA3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
MSH3 PCNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
ATM RAD17 â—¼   PHOSPHORYLATION 0.82 0.82 Signor 10608806
FBXO18 PCNA â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BRCA1 RAD18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29656893 25184681 23901102
CHD1L XRCC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23926104 19661379 19666485 28514442
FANCA FANCB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27986371 20347428 22343915 17396147 22705371 17289582
FANCB FANCG â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17396147 27986371 16720839
CCNA2 HELB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LRRK2 PRKDC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19826009 31046837 17400507
VCAM1 PRKDC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22623428 33961781 19738201
RFC1 RAD17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12400013 18245774
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
RNF4 ACTB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29180619 32296183 32521226
SOX2 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21280222 35140242 23667531
BMI1 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20668194 24457600 34316702
CCNA2 CCNA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
BRCA1 FANCD2 â—¼   UBIQUITINATION ✅ + 0.83 0.83 Signor 12485996
CHEK1 CLSPN â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RPA1 XPA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HIST1H3A YWHAZ â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRCA1 CDK2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 25252691 26831064
PRKDC BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10608806 25223785
SOX2 CDK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23667531 30297536
FANCC CDK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9242535 14499622
LMNA MDC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30179224 22412018 30419336
MDC1 RAD51 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28973861 16186822
NBN MLH1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17121922 10783165
LMNA PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30419336 22412018 25948554 29568061
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
RAD9A PCNA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 11994305 12400013
XRCC5 TOP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28415827 21679440
TOP1 TOP2A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15848144 26344197
PCNA XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12171929 11239001 24695737
LMNA PCNA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30419336 24623722 29753763
PCNA CCNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 7903056 33961781 8101826
AIFM1 HAX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
FANCF FANCL â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KAT2B SMAD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
PCNA POLE â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
FANCA BLM â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12724401 23509288 22343915 12973351 22705371
BLM TOP3A â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 20711169 8048867
BRCA1 TOP2A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15965487 25184681
TOP1 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28415827 15848144
XPC XPA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17154534 12486030
MCMBP MCM5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24299456
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
RPA1 RPA4 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
BRCA1 FANCA â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
DDB2 HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
ATM PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10608806 10464290
NBN BLM â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29523790 10783165
BRCA1 RFC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 25184681 10783165
BRCA1 CLSPN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15096610 22863316
BRCA1 CCNA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 9244350 10373534
PRPF19 CDC5L â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 19633697 7262047
CHTF18 PCNA â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
FANCF FANCC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17082180 27986371 11063725 15262960 24469828 23303816 18550849 16720839
HUS1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 11077446
KAT2A WDHD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21987584 21725360
H3F3A KAT2B â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
MLH1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15225546 32814904 28439008
MLH1 AIFM1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20706999 17148452
SLX4 MSH3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19596235 31495888
OTUB1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26752685 18954305
PCNA PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20129057 20302655 12930846 21690293 20303835
PARP1 TOP2A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 20085707
RAD18 PCNA â—¼   UBIQUITINATION ✅ + 0.86 0.86 Signor 19706603
RAD23B PSMD4 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 20059542 7307429
RNF4 SP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34550526 10617653 21983342 26511642
XRCC5 TOP2A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12393188 20085707
SOX2 EHMT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
ERCC2 XPA â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CCNA1 CDK1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ISG15 UBA7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CCNA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25091198 16713569 9244350 10373534
CDK4 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17334399 16713569 9244350 12509456
SP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14710355 16713569 12706836 10720440 17766039
BRCA1 MSH3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14578343 11498787
CDC5L BCAS2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 20467437 7945687
CDC5L TOP2A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11101529 20467437
CLK2 SETD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 23602568
DDB2 XPC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22039351 23319653 28760956 27203177 29604309 15882621
XPA ERCC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8999876 20541997
FANCA TOP3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12724401 22343915 12973351 21240188 22705371
FANCB FANCL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17396147 27986371 16720839
UBA7 ISG15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 16189514 25416956 16009940 16884686 14976209 22693631 17597759 33961781 18356159 20975683
XPC PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 28760956
HDGF PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21907836 34079125
CLSPN RAD9A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12766152 20424596
XRCC6 XRCC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 30585729
CDK5 CCNA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 33961781
SOX2 FOXC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
FANCD2 FANCE â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FANCF FANCG â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PARK2 PSMD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BLM CHEK1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMD4 SHFM1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHAF1A PCNA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 MLH1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HUS1 RAD17 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
RAD1 ZBTB14 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HIST1H3A KAT2A â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CHD1L PARP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ATM RAD17 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10608806 11418864 18344987
BRCA1 BLM â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25084169 10783165 26831064 29656893
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
FANCG BRCA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12915460 20450923 18212739 16621732
BRIP1 MLH1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CDC5L PRKDC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11101529 20467437
CHD1L XRCC6 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CHD1L XRCC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 19661379 33053171 33961781
ERCC6 ERCC5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16916636 8652557 16713569 16246722
POLD2 POLD1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 31449058
POLH POLI â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16763556 23248005 12426396 12606586
RAD51 RAD18 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25893307 19396164
CDK5 CCNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23602568 33961781 26186194 25852190 32707033 23455922
GATA4 SRF â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11158291 11003651
ATM BLM â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BRCA2 SHFM1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RAD18 RAD51 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HUS1 ZBTB14 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
RPA2 TIPIN â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
FANCC FANCG â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BRCA2 FANCD2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CHAF1A HIST1H3A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
ACTB POLR2A â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
POLD1 RPA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RPA1 XRCC6 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HLTF RAD18 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MDC1 ATM â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29656893 14519663 28943310 12607005 26734725 18006705
NBN BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10426999 18171670 19244116 12124328 10783165 25659039 25184681 25939603 11504724 29656893
MDC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 19766185 15569676 12611903 17525332 12607005 29656893
CCNB1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11278247 23246971 9244350
KAT2B BRCA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28985013 9824164 12815053
MLH1 BRIP1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5220047 17581638
CDK1 CCNA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24302728 21308745 26496610 33422522 14681455 23602568 25852190 33961781 12853968 26186194 17679094 32707033 9053846 8463339 19483727
CHD1L PARP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19666485 33053171 22146311 34079125 23926104 19661379
XPC ERCC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26278177 10734143
ERCC3 ERCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 8652557 17643375
PCNA ERCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10408173 16189514 16713569 9305916
FANCA FANCL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16116422 16474167 20347429 20347428 27398742 21975120 22705371 17396147 18174376 22343915 12973351 26269593 18550849 17289582 16720839
FANCG FANCC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15299017 16189514 25416956 27986371 10373536 11438206 10627486 11750104 23303816 18550849 15299030
FANCF FANCE â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17082180 27986371 15262960 16127171 26277624 20064461 12093742
KAT2B IRF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10022868 11304541
MSH4 MLH1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32814904 16189514 10928988
MUTYH PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 26377631 11092888
POLH RAD18 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16824193 23345618 21396873 29590477 15359278 21098111 18363965
RAD18 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21227930 23345618 26170230 31160570 21858012 22904075 32701997 28924044 31887036 17720710 20600238 18363965 20064529 30700555 31873223 17108083 15359278 18245774 33508099 20675655 24958773 27377895 30563767 28831681 21967848
CCNA2 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 12853968 26186194 10930425
CDK4 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 8259215 11254741 8101826
SP1 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11432852 10878024 12228247 22227581 16714330 11114293
PRKDC RPA2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
FANCL FANCD2 â—¼   UBIQUITINATION ✅ + 0.89 0.89 Signor 17396147
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
GRB2 WAS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
RAD17 RAD9A â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
RPA1 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
ATM BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11114888 11278964 29656893 10783165 11016625 10866324 10550055 15713674 18344987 10608806 17478428
ATM NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24800743 10783165 25088203 11252893 30952868 10608806 17507690 22464731 25895060 10839545 15758953 10839544
ATM BLM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29523790 10783165 12034743
RMI1 BLM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20360068 20826342 23509288 24239288 26496610 15775963 20064461 20711169
BLM TOP3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12724401 20360068 11406610 23509288 24239288 10734115 26496610 30279242 11470874 15775963 10825162 20711169
BLM MLH1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12724401 10783165 11691925 11325959 21466675 11470874 19015241
BRIP1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21240188
RAD51 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 31009828 11498787 16713569 19766185 25659039 19369211 25499220 9774970 28319063 17302439 9008167 14636569 28976962 24085845 34408138 29656893
MLH1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10783165 17148452 25184681 16786532 21240188 29656893
FANCA BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21240188 29656893 16713569 12354784
BRCA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11477095 17664283 16713569 21135251 19369211 9774970 25184681 14636569 24085845 34408138 25652403 14499622 29656893
CDK2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 16713569 10373534 9244350 8764100
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
CHEK1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18317453 24627786
RPA3 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
CCNB1 CDK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 34224728 18337751 9891079 24508230 17431037 9560267 14681455 17283331 8662825 19162005 16159883 25852190 20360007 19879842 12397081 11331587 9247342 26496610 20228808 25750436 12612082 16784539 23602568 20733055 27626412 20367638 8397206 10973963 9001210 20956543 33037310 8397207 23543736 32707033 2570636 30674583 10716937 27030811 18408765 24358021 20974803 7799941 33961781 26186194 17679094 23799914 8463339 26344197
CDK1 LIG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12851383
PCNA CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10930425
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
ERCC1 ERCC5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14517266 19940136 17948053
SLX4 ERCC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19596236 28514442 23033263 21240275 19596235 25538220 32398829 26186194 19595721 31495888 23623386 22902628 23093618
ERCC1 RAD51 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 14734547 17962301 18541667
ERCC5 ERCC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 32245994 8652557 16713569
GTF2H3 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9118947 8652557 10734072
ERCC6 EHMT2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16186106 18656484 12419226
FANCA FANCE â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12239156 12724401 15262960 24469828 16116434 11157805 22343915 17396147 12093742 12973351 15082718 23303816 18550849 22705371 24451376
FANCA FANCG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15299017 17671210 11739169 16189514 12724401 10373536 28514442 11167740 11438206 25132264 20347428 21975120 10961856 24910428 11050007 10567393 12973351 11181053 14697762 12210728 22705371 31467278 20347429 18212739 11157805 12444097 22343915 15082718 15192709 18550849 12649160 12239156 11063725 19109555 28215707 26264872 11918676 11161829 15138265 17396147 10652215 23303816 17289582 11297559 10468606 15367677 12692539 10627486 19321451 32814053 33961781 20450923 31980815 16621732 16720839
FANCA FANCC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17671210 16189514 27986371 12724401 10373536 11167740 10961856 20864535 12973351 12210728 22705371 15299030 12444097 11750104 22343915 15082718 18550849 9398857 9742112 12239156 11063725 28215707 17396147 10551855 23303816 11297559 10210316 16116422 12692539 10627486 19321451 9789045 33961781 16720839
FANCA FANCF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27986371 12724401 24469828 20347428 12973351 22705371 17082180 12444097 11750104 22343915 15082718 18550849 12649160 11063725 28215707 15262960 17396147 20064461 23303816 21109493 16116422 19321451 16720839
FANCE FANCC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12649160 12239156 27986371 16513431 15262960 24469828 16127171 11157805 14625294 26277624 12093742 33961781 23303816 18550849 24451376
FANCG FANCE â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12239156 15262960 11157805 12093742 24451376
FANCF FANCG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12649160 17082180 27986371 11063725 15262960 18212739 11157805 20450923 16621732 16720839
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
GTF2H3 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8652557 15790571 10734072
PCNA HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
HLTF PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18719106 26350214
HSF1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12919958 9325337
RAD9A HUS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 14611806 14624239 14681455 11907025 12628935 32296183 9872989 10852904 19464297 10777662 10359610 11994305 11340080 15314187 26088138 33961781 26186194
RAD17 HUS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 12578958 33961781 19535328 26186194 10884395 27387238
KAT2A KAT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23667505 23555303 21559432
KAT2B IRF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022868 11304541
SP1 MACROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18206366 15691879
MDC1 NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15377652 30179224 12607003 18678890 29656893 27590578 25064736 20460517 19804756 23115235 14519663 15201865 12607005 20224574 18001824 18583988
NBN RPA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NBN RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
XRCC1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 15555565 9584196 18971944 24778456 15044383 34111398 14500814 30260704 20302655 12897160 34079125 20303835
TOP1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 15247263 15848144
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
POLA1 POLE â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLA1 POLE2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLA1 POLE4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLA1 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLA2 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 8223465
POLE POLA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLE2 POLA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLA2 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
POLA2 POLE4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLA2 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLD2 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16000169 10852724 16510448
PRIM1 POLE â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
PRIM2 POLE â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
PRIM2 POLE2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
PRIM1 POLE2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
PRIM2 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
POLE4 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 6693436 10801849 9405441
PRIM1 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
PRIM2 POLE4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
PRIM1 POLE4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
SPRTN POLH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 22681887
POLI PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23248005 26903512 18931444 16763556 33166398 11724965 15342632 34165573
XRCC5 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15941674 10750018 20023628 17308091 15758953 20085707 33005030 10446239 26496610 19303849 20711232 9312071 26446488 15520013 28154079 28345663 16857680 12393188 22404984 21679440 26344197
XRCC6 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20711232 21575865 33005030 28345663 15941674 10064605 26496610 26446488 15520013 10750018 8422676 26175416 22939629 17308091 30585729 19303849 21969602
RAD17 RAD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 12578958 33961781 19535328 11418864 10884395 27387238
RAD17 RFC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14624239 33961781 14605214
RAD17 RFC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 14624239 33961781 14605214
RAD17 RAD9A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 20424596 14611806 12578958 11572977 25091155 19535328 10884395 27387238
RMI1 TOP3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20360068 20826342 16537486 15775963 20064461 24509834 26186194 33961781 20711169
SP1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843607 20160399 23704280
SIRT1 XPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20670893 30327428
XRCC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 15107487 34111398 30260704 20227374
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
PDPK1 XRCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMAD3 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16469949 12207925 15525600
SP1 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14561739 16452190 9295358
MCMBP MCM5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24299456 25036637 22540012 33961781 17296731 26344197
ATM RAD17 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ERCC1 SLX4 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
RMI1 BLM â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711169 8048867
BLM RMI1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 20711169 8048867
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CHTF18 RFC4 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FANCD2 FANCL â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
POLA1 POLD3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ERCC5 GTF2H1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
POLD2 POLD4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
REV1 POLI â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 30886224 19170759 15189446
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
TOP1 TOP2A â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
RPA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ERCC2 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC6 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
POLI REV1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
POLD3 POLD4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
GTF2H4 POLR2A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
FBXO18 RAD51 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
GINS1 POLE2 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
REV1 POLK â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 26903512 15380106 15189446 19170759 26982350
CHTF18 RFC5 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
POLE2 POLE4 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
GTF2H1 POLR2A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CHTF18 POLE â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
POLD3 REV1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
POLE3 POLE4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
MLH1 MSH3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 29892012 25416956 17148452
DROSHA DGCR8 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 22222205 8308421
BLM MLH1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHTF18 RFC2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RAD17 RFC5 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HLTF PCNA â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18719106 26350214 22904075 30696947 32701997 28924044 18316726 31973093
RAD51 RPA1 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ERCC5 ERCC2 â—¼   PHYSICAL_INTERACTION ✅ + 0.95 0.95 Signor 20840796
POLA1 WDHD1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PPP4C PPP4R2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PCNA POLL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PCNA TOP1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BLM TP53BP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CDC5L RNF113A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GTF2H1 XPC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PRPF19 RNF113A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
POLE POLE4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CCNB1 CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 20733051 28514442 9891079 7799941 8397207 25852190 26496610 33961781 26186194 23602568 10995390 23455922 30674583 18471975
PCNA CDK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12361598 28514442 26496610 29510343 9545286 33961781 26186194 7903056 21319273 10930425
FANCA FANCG â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 17396147 5219816
HLTF RAD18 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18719106 23555860 21396873 25023518 18316726
RFC2 PCNA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9228079 12171929 24958773 26496610 8093561
RFC5 PCNA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9228079 12171929 16189514 24958773 8999859
RPA1 RPA2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24207024 22939629 26399832 26496610 24981860 16514417 19214185 26344197
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
POLR2A SETD2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
MCM5 WDHD1 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
ERCC3 POLR2A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CHEK1 TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RAD17 RFC2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
BLM RAD51 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19671661 29523790 12606585 17984114 11309417 11278509 19956565 18562274 15064730
BRCA2 RAD51 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9405383 19875419 23935068 14580352 9774970 15937124 11239456 21076401 10551859 16513631 21601571 25585578 12815053 16793542 11477095 26833090 21670257 26145171 18264088 15713648 9811893 12941707 25282148 20729832 26387543 24835992 18429819 15800651 17515903 21399666 18317453 22116401 11313963 33476590 14636569 15897881 15800615 10373512 9523196 9126738 27941124 17541404 12442171 9560268 20729859 12619154 16914443 28765325 17515904 31113933 28757209 15065660 19303847 28168276 19628690 12606939 24013206 24981860 20871615 15671039 22293751 21789034
XPA ERCC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 25416956 18597777 11058119 7598728 24036546 9013642 9653453 7876167 8972858 19056823 8197174 16491090 26186194 33961781 17948053
ERCC3 ERCC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15220921 9118947 8652557 19934020 16669699 33381997 8152490 22939629 22678362 26340423 27193682
HUS1 RAD1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 20847938 14624239 10359610 9872989 14681455 15122316 33961781 19464297 26186194 11944979 10777662 11340080
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
MSH3 PCNA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12171929 25416956 32296183 11274057 11005803
REV1 POLH â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16824193 15380106 15189446 19170759 21690293 22828282 22691049
POLH PCNA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 23345618 27770570 24474685 30963698 15149598 31796584 16763556 23388460 15342632 25766642 21855803 21791603 20129057 23042605 30563767 26988343 22989887 28831681 11585903 20159558 23761444
RAD9A RAD1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 14611806 15314187 10359610 11572977 11340080 26088138 9872989 25091155 25602520 11907025 10852904 33961781 26186194 10777662 11994305 12628935
RFC4 RAD17 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 14624239 11907025 33961781 14605214 12400013
PCNA RFC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12171929 12192049 22939629 9649448 15225546 24958773 12045192 26496610 10353443 8861969 30301766 9092549 8999859 12400013 26344197
RFC1 RFC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9488738 14681455 15655353 18245774 22939629 26344197
PCNA RFC4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9228079 12171929 16189514 22939629 24958773 26496610 10051561 12400013
HLTF PCNA â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
GINS1 TIPIN â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
POLE2 POLE3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
LIG3 XRCC1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
BRIP1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5220047 17581638
RAD51 BRCA2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219969 17541404
RFC1 RFC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 22939629 14681455 33961781 18245774 9092549 26344197
RFC1 RFC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 14681455 33961781 18245774 22939629 26344197
CDK4 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK5 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BLM RPA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BRCA1 BRIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
HIST1H3A KAT2B â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
POLE POLE3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PCNA RAD18 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MCM5 MCMBP â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
LIG1 PCNA â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
GINS1 WDHD1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
GINS1 MCM5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CCNA2 CDK2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 8475101 28514442 16431923 33854235 11940657 10559988 15189033 17361108 16290148 14681455 17254966 8662825 25852190 15557281 23455922 19483727 18471975 11141566 10924145 15828833 21241890 19631451 11377199 18177895 8684460 26496610 9716181 12853968 11907280 23602568 9724724 15647383 14656438 19773423 12941338 15239650 24302728 25669885 15890360 7630397 8756328 8397207 21447625 22231403 20733051 9660939 24358021 12044161 33422522 11983168 33961781 26186194 7553852 16209941 12244298 9380407 8463339 15455144 10930425
RFC2 RFC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9228079 9751713 28514442 9488738 22939629 8692848 15655353 33961781 24981860 16582606 9092549 26344197
BLM RAD51 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POLH REV1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RAD17 RFC4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RMI1 TOP3A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDK2 PCNA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ERCC2 GTF2H4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA FANCG â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA FANCC â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FANCA RMI1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HUS1 RAD9A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BRCA1 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
DGCR8 DROSHA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RAD1 RAD9A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMD4 RAD23B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
USP1 WDR48 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ERCC2 GTF2H3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
POLD1 POLD4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PCNA RFC5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PRIM1 PRIM2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC5L PRPF19 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLA2 PRIM2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLA2 PRIM1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLD2 POLD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLE POLE2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BCAS2 PRPF19 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RFC1 RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RFC2 RFC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
BCAS2 CDC5L â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H3 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
CDK2 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
MLH1 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
CDK5 ATM â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12556884 16332722 16858402 17303408 19151707 20724832 21727086 21922195 23589330 23850759
ATM RPA2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM CHEK1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM FANCD2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
MLH1 ATM â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
AURKB ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22099307 27493659
CDK5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17303408 23589330 16858402 19151707 27470939 16332722 12556884 21600237 21922195
ATM BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 18662573 16122425 25077544 16122426 21113148 17525332
ATM SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23148884 18619531 22826432 27156884 29144413 29294106 23046908 17609267 18171990
ATM RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 29875999 15964794 11877377 17303408 9725899 16163361 14872059 23847781 9139719 10713094 9295339 20860841 16731533 12607003 22977173 7171818 15459660
ATM FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 16280053 17303408 15057286 12427531 15607958 25891850 16163361 21466974 20068231 14499622 17570479 12086603 19774700 23847781 14599770 15964794 22057367 28825622 12607003 17525332 15459660 16943440 15979372 11877377 27094386 15279770 28552166 12612651 19101576
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM RAD17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11418864 14500819 27364693 17570479 10608806 17110331 11687627
ATM RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17525332 11359916
ATM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16199871 11146546 25766002 17984114 14643436 20719863 17363339 14729972 18054789 12034743 30496191 16880735 11375976
ATM RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11278446 26658951 17570479 22453082 12709442 18669648
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17525332 19109555
ATM CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 69.0 1.0 Omnipath 29774099 20976184 26683224 25663895 12676583 17303408 14657349 29167438 27545311 10859164 19056039 15485915 28808226 12588868 16163361 15650047 12676962 17570479 14988723 14681223 26516160 10608806 26069190 29741650 12676925 23847781 17118344 11252893 20376879 15964794 15149599 18691976 19059218 20068082 15707391 12607003 25450480 17525332 11553781 19646247 15870257 15459660 20798862 19716789 11877377 12660173 11390642 15674326 16782033 28396830 28228262 12446774 15533933 15212693 29555944
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATM SLX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21655083 17525332
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
CSNK1E BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11583622 12598529 20356928
MAPK8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18594987 25326334 25077544 27374471
NBN BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM FANCG â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM TOP3A â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCC â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCA â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCG â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM TOP3A â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCC â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 22973052 23253856 24089143 24095737
BLM FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19622405
RMI1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 15775963 23509288
CHEK1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21050475 20719863 25015292 25906194 15364958
BLM CHAF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15143166
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 BRCA2 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 FANCD2 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 BRCA2 â—¼   SHARES_COMPLEX 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 FANCD2 â—¼   SHARES_COMPLEX 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
USP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
BRCA1 DDB2 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
BRCA1 CHEK1 â—¼   REGULATES ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
SP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15252835 17373631 18377656 19466541
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
CDK2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8764100 10373534 10550055 19683496 16713569 26719576 15212693
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
BRIP1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 22032289 21240188 34591612 18285836 16713569 14576432 17596542 17525342 17525340 15242590 25184681 19369211 18369654 28911102 17581638 15125843 11301010 15133502 19452558 27399284 18717574 17525341 22792074 14576433 20173781 11877378 20681793 14578343
CDK4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9244350 16713569 17334399 20932174
BRCA1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12887909 12485996 11239454 25652403 14499622 16713569
PCNA BRCA2 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 BRCA2 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 FANCC â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
BRCA2 FANCG â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
BRCA2 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 BRCA2 â—¼   SHARES_COMPLEX 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA BRCA2 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 FANCC â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
BRCA2 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 FANCG â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 15496928 15549137 15655342 16337602 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 22266823
USP1 BRCA2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
FANCD2 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17145710 19861535 15115758 18212739 15199141 10749118
BRCA2 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 17145710 21601571 15937124 17541404 11313963 16914443 26145171 21670257 18264088 19303847 25585578 12815053 16793542 21789034 25282148 17515904 9126738 20729859 15703751 21076401 15065660 22293751 19875419 12606939 22116401 12619154 23935068 15800615 33476590 15800651 15671039 11477095 16513631 9811893 10551859 20729832 9523196 14636569 17515903 12442171 9405383 26833090 21399666 19628690 9560268 10373512 14580352
TOP3A BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRIP1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RPA1 BRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17596542 19419957
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
LMNA CDK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 RPA3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK1 MCM5 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK1 RPA1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK1 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17243194 17303408 17660363 18414028 18590585 7575488
CDK1 RPA2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
CDK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 7575488 18590585 17243194 17303408 21524151 17570479 25607646 29603287 20126263 17660363 30685087 15279786
CDK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 82.0 1.0 Omnipath 19007248 16565220 17081983 22120848 18767875 9168797 19690332 27603133 15766329 12761892 19413330 21465480 19664995 16260496 19415658 25960391 18578522 20068231 15713670 17570479 24073199 18491316 18669648 18691976 17287340 15345747 20068230 19651622 20058876 19691289 17924679 16542212 19369195 25184044 18707149 7983050 19584300 16964243 21422740 18212344
CDK1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20798862 19837665 18691976 21765472 21907702 29092815 18983824 16629900 22686412 24242917
CDK1 RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 9139719 17303408 9295339 19793801 15279786 7575488 20068231 17116885 19671522 17582221 26237679 18590585 1318195 22977173 17660363 20932174 17296725 17102137 21664290
CDK1 RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20021694 12734188 18940270 12709442 24098381 26860083 23028682
CDK1 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19107194 17570479 24011073 28756945
CDK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25398907 28831131 20150555 22266860
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDK1 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 19007248 16565220 20166139 17081983 18767875 20393185 23870088 17137347 19413330 18187866 19194518 30190500 19664995 19415658 15302935 7925482 16083285 95010153 24741066 20068231 18452278 18077418 17570479 18491316 18669648 32071079 23427156 2344612 18691976 26922519 17287340 18815303 20068230 19651622 20058876 19691289 17924679 22367880 19165338 19664994 18707149 21389115 16964243 18212344 24556839
CDK1 FANCG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15367677 9242535 18212739
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK2 MLH1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
CCNA1 CDK2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16189514 15583032 25241761 16777603 10559988 14681455 9636170 16159883 9041194 10652300 8565853 12970441 14701826 8397206 14681231 11264176 8397207 15601848 12191604 12190313 7799941 19423708 12800980 16009130
CDK2 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10197981 11283614 12193595 14536078 15147722 15241418 15279786 16156666 17055429 17303408 17660363 18590585 18636226 20027199 20713526 2191300 28536364 7575488
CDK2 RPA2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM5 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
CDK2 LIG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17040896
CDK2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 10197981 15241418 19218245 25241761 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 15212693 19114991
CDK2 HIRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20068231 11238922 19413330
CDK2 LIG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12851383 10930425
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21765472 21965652 21907702 18983824 24242917
PARP1 CHD1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22146311 19666485
HUS1 CHEK1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RAD1 CHEK1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
PCNA CHEK1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
RAD17 CHEK1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM5 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
CHEK1 RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
HUS1 CHEK1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RAD1 CHEK1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD17 CHEK1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
PCNA CHEK1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
HUS1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD17 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 FANCE â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17296736 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 FANCG â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 FANCD2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14988723 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 FANCA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CHEK1 RPA2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM5 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 CHEK1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 CHEK1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 CHEK1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM5 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 26610585 27685627 18285803 22730303 18317453 22705496 29977027 19473886 22665067 25852742 25909291 24847116 24204313 15665856 24238855
CHEK1 CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18451105 15707391 16123041 21680713 22655267 12766152 16963448
CHEK1 FANCE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17296736 17296725 18995830 19686080 27094386 18677104 19473886 15798197 17102137 17116885 17582221 19793801 19061902 17384638 18931676 15459660
CHEK1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23321637 22024163 17276342
CHEK1 FANCG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17296725 19686080 18677104 15798197 17102137 17116885 17582221 19793801 17384638 18931676 15459660
CHEK1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17296725 19686080 22057367 19861535 18677104 15798197 17102137 17116885 17582221 19793801 14988723 17384638 18931676 15459660
CHEK1 FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17296725 19686080 18677104 15798197 17102137 17116885 17582221 19793801 17384638 18931676 15459660
POLK CHTF18 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
XRCC1 CHTF18 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA CHTF18 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 CHTF18 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
XRCC1 CHTF18 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA CHTF18 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
POLK CHTF18 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 CHTF18 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
XPA DDB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
CLSPN DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17196446
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
RPA2 ERCC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 XPA â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 MLH1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 10882712 11900249 12648680 12947387 15703371 16612326 16697054 17036055 17884153 18157157 18406444 19473888 19595721 19596235 19596236 19686080 19805513 19809470 19847258 20478261 21376743 22101340 22257761 22373527 22743550 22824526 23085398 24050180
RPA2 ERCC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 XPA â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 MLH1 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 10882712 11900249 12648680 12947387 15703371 16612326 16697054 17036055 17884153 18157157 18406444 19473888 19595721 19596235 19596236 19686080 19805513 19809470 19847258 20478261 21376743 22101340 22257761 22373527 22743550 22824526 23085398 24050180
XPA ERCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19056823 26186194 8972858 18597777 25416956 9653453 7876167 11058119 17948053 7598728 8197174 16491090
ERCC2 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC5 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8652557 16713569 20840796
GTF2H1 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9130708 8652557 10734072
ERCC2 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10734072 8652557 10024882 16669699
ERCC2 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12820975 10734072 9771713 8652557 16189514 19934020
ERCC3 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H1 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10403766 10734072 9173976 8194528 15220921 9118947 9130708 8652557 11259578 26340423 17643375
ERCC3 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9118947 8652557 16189514 10734072
RPA2 ERCC5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17000769 9699634 7700386 15590680 9716411 17466625
RPA1 ERCC5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17000769 9699634 7700386 15590680 9716411 17466625
ERCC5 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17000769 9699634 7700386 15590680 9716411 17466625
ERCC6 ERCC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16916636 8652557 16713569 16246722
ERCC5 GTF2H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15195146 16713569 8652557 11259578
ERCC5 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 18079701 10408173 16713569 19279666 9305916 20713449
FANCC FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCA â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCA â—¼   PROTEIN_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCA â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCA FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 16116434 12724401 22343915 24451376 11157805 22705371 12239156 12093742 18550849 17396147 15262960 12973351 15082718
FANCA FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCL FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCB â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF FANCB â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCB FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCG FANCC â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15496928 15549137 15655342 16337602 16697054 17035102 18001825 18157158 18171670 18212739 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19270065 19282663 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCC â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 15496928 15549137 15655342 16337602 16697054 17035102 18001825 18157158 18171670 18212739 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19270065 19282663 19490890 19622404 19686080 19772495 19793861 19793862 19841479 19847258 20021983 20064462 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCC FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 26277624 17145710 24451376 12649160 11157805 16127171 12239156 12093742 18550849 16513431 15262960 14625294
FANCC FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 22615860 19622404 11751423 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
PCNA FANCD2 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA FANCD2 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
USP1 FANCD2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
FANCL FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCL FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 17396147 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 19622405 18985065 18550849 21948210 22657828 20832754 19686080 12535671
WDR48 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19264559 19686080 18082604 23589330 19622404 19075014 18082605 19217432 18931676
USP1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19264559 19686080 18082604 23589330 36170365 19622404 19075014 16633336 18082605 19217432 18931676 15694335
FANCF FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCE FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 22615860 24451376 12649160 17308347 19622404 12972610 23253856 15136767 19282663 12093742 14988723 8020957 24095737 18931676 26277624 22266823 16697054 24089143 16513431 19704162 23444773 19772495 19847258 15115758 16127171 18550849 21948210 22657828 20832754 19686080 12535671
FANCD2 SLX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21464321
FANCG FANCE â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCE â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCE TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL FANCF â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL FANCF â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCF TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 20450923 12649160 11157805 16621732 17082180 11063725 18212739 16720839 15262960
FANCG TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCG FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCL TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
WAS GRB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
GTF2H1 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H1 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21988832 10734072 11062469 9130708 8652557 8194529
GTF2H2 GTF2H4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H2 GTF2H3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
MAPK8 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 19651622 17081983 10747973 20166139 18767875 20068231 18669648
RAD17 HUS1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RAD1 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
HUS1 TIPIN â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RAD17 HUS1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RAD1 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
HUS1 TIPIN â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 TIPIN â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA3 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA2 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 MCM5 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 TIPIN â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11077446 16189514
UBE2L6 ISG15 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11157743 15485925 18583345 15131269
KAT2A SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11058129 15009097
SP1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20130956 20144149 17882273 15647279
KAT2B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11058129 15994459
PARP1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
XRCC1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
XRCC1 LIG3 â—¼   PROTEIN_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
LIG3 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9705932 20227374 17353931 11163244 26496610 16713569 8264637 11352725 9136882
XRCC5 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
PCNA MLH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20154325 22118461 11274057 23840062
NBN TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBN RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN PARP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
SIRT1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17612497
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 XPA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
CDK5 PARP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12556884 16332722 16858402 17303408 19151707 20724832 21727086 21922195 23589330 23850759
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PARP1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9563011 9518481
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
POLA1 POLD4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA1 POLD2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA1 POLD1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA1 POLD1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLA2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLD1 POLA2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA2 POLD4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA2 POLD3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLD2 POLA2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLA2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
LIG1 POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
POLD4 POLD1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD1 PRIM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLD1 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD1 PRIM1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLD4 POLD1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD1 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 PRIM2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 PRIM1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9286699 12403614 16510448
POLD1 POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12403614 16510448
POLD4 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PRIM1 POLD3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
LIG1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
PCNA POLD3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PRIM2 POLD3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLD3 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD3 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD3 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PRIM1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PRIM2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD3 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
LIG1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
PRIM1 POLD4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
PRIM2 POLD4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
PCNA POLD4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA POLD4 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PRIM2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PRIM1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24022480 9038370 16510448
REV1 POLH â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10884424 11756412 12466554 14624239 14657033 14726013 15189446 15688063 15703371 16337601 16337602 16611994 16697054 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 1974050 19847258 20129063 20675655 22021614 22266823 22562137 23065650 23414611
PCNA POLH â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15703371 16337601 16337602 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 22021614 22266823 22562137 23065650 23414611
POLH RAD18 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
REV1 POLH â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10884424 11756412 12466554 14624239 14657033 14726013 15189446 15688063 15703371 16337601 16337602 16611994 16697054 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 1974050 19847258 20129063 20675655 22021614 22266823 22562137 23065650 23414611
PCNA POLH â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15703371 16337601 16337602 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 22021614 22266823 22562137 23065650 23414611
POLH RAD18 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
PCNA POLH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20129057 20159558 24474685 16357261 16189514 19208623 30963698 15342632 21855803 15149598 23042605 21791603 23761444 23345618 16763556 11585903 23388460 25766642 26988343 27770570
POLH REV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22828282 19170759 15189446 34725419 24409475 22691049 19157994 16824193 21690293 15380106
PCNA POLI â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
REV1 POLI â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
PCNA POLI â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
REV1 POLI â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11756412 12466554 14624239 14726013 15189446 15703371 16697054 17035102 17652783 18196958 18931676 19258535 19622404 19686080 1974050 19847258 22021614 23065650 23414611
PCNA POLI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16763556 26903512 15342632 23248005 11724965 19208623 16357261 18931444
XRCC1 POLK â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 POLK â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA POLK â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11900249 12466554 12648680 12930902 14624239 14657033 14726013 15189446 15189466 15459660 15703371 16697054 17035102 17116885 17296725 17582221 17652783 17884153 18087292 18157158 18196958 18584027 18677104 18809224 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22266823 22743550 23065650 23414611 24050180 8264637 8978692
POLK REV1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 23065650 23414611
RPA2 POLK â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA POLK â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11900249 12466554 12648680 12930902 14624239 14657033 14726013 15189446 15189466 15459660 15703371 16697054 17035102 17116885 17296725 17582221 17652783 17884153 18087292 18157158 18196958 18584027 18677104 18809224 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22266823 22743550 23065650 23414611 24050180 8264637 8978692
XRCC1 POLK â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
POLK REV1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 23065650 23414611
PRKDC POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC5 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PCNA POLL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12368291 11784855 16174846 16189514 12081642
PRKDC MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11749722 16319174
PRKDC RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 26811421 9139719 9295339 21300785 28046023 27999209 23684611 19704001 24332808 18289945 15703371 21558276 21731742 20016603 19473888 24819595 21175350 8760901 33826602 19843584 32989256 24830725 19808869 20154705 17570479 25733714 33636182 18669648 23677613 21376743 14872059 22057367 24639502 17035231 31527085 30030458 20691907 17928296 21107010 22977173 11731442 15060176 23319600 19772495 19847258 26166705 29875999 28506294 10064605 34385259 16731533 33357448 19346677 16697054 8943020
PRKDC SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 8407951
RAD17 RAD1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 TIPIN â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RAD17 RAD1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 TIPIN â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 TIPIN â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA2 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 MCM5 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA3 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 TIPIN â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD17 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA3 RAD17 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 RAD17 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RAD17 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 TIPIN â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD17 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD17 TIPIN â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD17 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD17 TIPIN â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA2 RAD17 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 RAD17 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 RAD17 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 MCM5 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD17 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD17 TIPIN â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA1 RAD17 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RAD17 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 RAD17 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16189514 12578958 18082599 10884395
RPA3 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD2 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
REV1 RAD18 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
RPA2 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
REV1 RAD18 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
RAD18 PCNA â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10884424 15280666 15688063 16611994 16824193 17652783 18157158 18196958 18363965 18498753 19013543 19258535 19396164 20129063 20675655
RAD18 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18363965 19706603 17652783 18196958 18498753 20129063 21227930 10884424 19013543 18157158 15280666 19258535 16611994 19396164 20675655
XPA RAD23B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
PCNA RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
USP1 RAD51 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
RPA3 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RPA2 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RPA1 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
PCNA REV1 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16337601 16337602 16697054 17035102 17517887 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 22562137 23065650 23414611
PCNA REV1 â—¼   PROTEIN_INTERACTION 30.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16337601 16337602 16697054 17035102 17517887 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 22562137 23065650 23414611
PCNA RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8999859 12400013 15225546 19285992 10353443 12192049 9649448 26496610 12045192 12171929 24958773 8861969 9092549
RFC5 RFC2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 28514442 9488738 8692848 33961781 24981860 22939629 26344197
RFC5 RFC4 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 16189514 9488738 25416956 22939629 28514442 29892012 32296183 26264872 8692848 33961781 24981860 30021884 9092549 26344197
TOP3A RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
TOP3A RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
LIG1 RPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
TIPIN RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 MCM5 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM5 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 MCM5 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
TIPIN RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
XPA RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12527904 19446504 7665601 8972858 7876167 20304803 7565690 9535929
TIPIN RPA2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 XPA â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 PCNA â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 MCM5 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 SPRTN â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23042605 16139798 24768535 23042607
RPA2 LIG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RPA2 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 PCNA â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 MCM5 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XPA â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 MCM5 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
TIPIN RPA2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
XPA RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12527904 19996105 10982866 8972858 20304803 7876167 11081631 7565690 32296183 20670893 9535929
TIPIN RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
LIG1 RPA3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RPA3 SPRTN â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23042605 16139798 24768535 23042607
RPA3 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 MCM5 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM5 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 MCM5 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
TIPIN RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
MAPK8 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 29578371 17081983 19007248 23434668 21540183 22622703 17924679 18187866 24296261 18838864 19413330 20027304 21471201 19107194 16964243 18669648 15302935
SIRT1 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17334224 16189514 15205477
TAF1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10086334 22711989 11287574 9334328 9388200 17166848
CLSPN TIPIN â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
TIPIN CLSPN â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15707391 20233725 12545175 22977173 21680713 16885023
TIPIN MCM5 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN TIPIN â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11877377 12086603 12766152 12875843 14988723 15136767 15175241 15459660 15798197 16713580 16805667 16880517 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 20051983
TIPIN MCM5 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TIPIN MCM5 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TOP1 LIG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14699148 13679147
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
UBE2L6 UBA7 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11157743 15485925 18583345 15131269
CDK5 USP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12556884 16332722 16858402 17303408 19151707 20724832 21727086 21922195 23589330 23850759
USP1 PCNA â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
WDR48 USP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32951278 18082604 34128540 23116119 23463011
USP1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19264559 35324534 19686080 18082604 23589330 20353596 19622404 19075014 16531995 18082605 19217432 18931676 33619839
LMNA VRK1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 Reactome 16495336 16704422 12493765 11285238 10908652 15546916 22770216 17170708 7937898 16371512 9465049 11792822 16339967 15681850
PCNA XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA CLSPN â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA CLSPN â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA POLD2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
LIG1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12171929 9649448 28073635 10559261
LIG1 POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
POLD2 PRIM1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLD2 PRIM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLD2 PRIM1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 PRIM2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
SRF ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18804439 15837932 1762920 9571041
TCF7L2 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22552774 12750294 26947016
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
AURKB VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 14762106 14722118 11895474 17081983 19007248 11420699 15676024 12458200 18669648
SMAD3 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
CDK4 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10197981 12193595 15241418 16156666
SMAD3 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
CDK4 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 34003249 10197981 15241418 25241761 19920136 15520018 20068231 17099224 16156666 16189514 19413330 14512875 12193595 33051597 19114991
MAPK8 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10601313 25714018
CLSPN MCM5 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM5 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN MCM5 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
AURKB CENPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14667408 18239465 11756469 15108802
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
SP1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14603527 15739164 11133225 12905482
SP1 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15922873 10196209
SP1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15908479 16341057 9671487 1845987 8803927 2542772 7565693 15608673 9566920 1404598 2170405 10421838
MAPK8 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28831131 22266860 18199680 19245816 25398907 17570479
SP1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15737644 15710382
LMNA CCNB1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
MAPK8 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18985696 25862939 15696159 11956222 19788416 21081103 15071501 18559254 7890696
ATG101 RB1CC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20562859 23392225 19597335
NKX2-5 GATA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19479054 15653675 16137232